IMGT Repertoire (IG and TR)

Sumatran orangutan (Pongo abelii) TRB locus on chromosome 6

The Sumatran orangutan (Pongo abelii) TRB locus is on chromosome 6. The orientation of the locus is forward (FWD).
The Sumatran orangutan (Pongo abelii) TRB locus spans 703 kilobases (kb), from 10 kilobases (kb) upstream the most 5' gene in the locus, TRBV1-1 (P), to 10 kilobases (kb) upstream of the most 3' gene in the locus, TRBV30 (F). The Locus representation encompasses 800 kilobases (kb) including the 5' borne MOXD2 and the 3' borne EPHB6.
The Sumatran orangutan (Pongo abelii) TRB locus consists of 96 genes : 78 TRBV genes belonging to 33 subgroups, 2 TRBD genes, 14 TRBJ genes belonging to 2 sets and 2 TRBC genes .
The TRBV genes span 640 kilobases (kb), the TRBC genes, the TRBJ genes and the TRBC genes spans 63 kilobases (kb).

MOXD2 (5' borne) has been identified 83 kb upstream of TRBV1-1, the most 5' gene in the locus.
EPHB6 (3' borne) has been identified 42 kb downstream of TRBV30, the most 3' gene in the locus.

References:

[1]	Calvas P. et al., Scand. J. Immunol., 49, 595-610 (1999) PMID: 10354371
[2]	Scinicariello F. and Attanasio R., Immunology, 103, 441-448 (2001) PMID: 11529934
[3]	Sumiyama K. et al., Mol. Biol. Evol., 19, 1093-1099 (2002) PMID: 12082128
[4]	Fortenfant F.et al., Unpublished (2002)
[5]	Scinicariello,F. et al., Immunology 111 (1), 66-74 (2004) PMID: 14678200
[6]	Gibbs R.A. et al., Science. 316(5822):222-234 (2007) PMID: 17431167
[7]	Rogers K.A. et al., Immunology 118(1):88-100 (2006) PMID: 16630026

More information:
Gene table: Sumatran orangutan (Pongo abelii) TRBV
Gene table: Sumatran orangutan (Pongo abelii) TRBD
Gene table: Sumatran orangutan (Pongo abelii) TRBJ
Gene table: Sumatran orangutan (Pongo abelii) TRBC
Potential germline repertoire: Sumatran orangutan (Pongo abelii) TRBV genes on chromosome 6