Table of alleles: Human TRBV

Print of this table: Folch, G. and Lefranc, M.-P., Exp. Clin. Immunogenet., 17, 42-54 (2000). PMID:10686482

Click here to seePart 1 - TRBV genes at 7q34

Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

The IMGT allele table refers to the V-REGION polymorphism. It does not include polymorphisms in the other parts of the V-GENE. V-REGION alleles are only described for genes which have at least one Functional or ORF allele. The accession number of a reference sequence is given for each allele.

Click on a gene name to get the alignment of the corresponding V-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).

Part 2 - Orphons on chromosome 9 (9p21)

TRBV
subgroup		 TRBV
gene name		 Fct TRBV
allele name		 Accession number Confirmed
by genetics
and/or data		 Description of mutations
20 20/OR9-2 ORF V20/OR9-2*01 L05149 + a1  ,S1  |a163  ,55T  |a277  ,93S  |
[ORF] V20/OR9-2*02 X72718   a1>g,S1>G|a163>g,55T>A|a277>t,93S>C|
ORF V20/OR9-2*03 AF029308            |a163>g,55T>A|
21 21/OR9-2 P(2) V21/OR9-2*01 AF029308 +  
23 23/OR9-2 P(3) V23/OR9-2*01 AF029308 + c253  ,P85  |
ORF V23/OR9-2*02 L27615   c253>g,P85>A|
24 24/OR9-2 ORF V24/OR9-2*01 L05153   c14  ,5T  |a65  ,22E  |a91  ,31R  |c147  |a152  ,Q51  |a164  ,Y55  |              |g181  ,D61  |g205  ,G69  |c238  ,R80  |c248  ,A83  |t278  ,S93  |t284  ,I95  |              |               |g327  ,L109  |
P V24/OR9-2*02 L27613   c14>t,5T>I|a65>c,22E>A|a91>g,31R>G|c147>g|            |a164>g,Y55>C|180^181>ins^a#|g181>t,D61>Y|g205>a,G69>R|c238>t,R80>*|c248>a,A83>E|
P V24/OR9-2*03 AF029308   c14>t,5T>I|           |a91>g,31R>G|c147>g|a152>g,Q51>R|a164>g,Y55>C|180^181>ins^a#|g181>t,D61>Y|g205>a,G69>R|c238>t,R80>*|c248>a,A83>E|t278>c,S93>P|t284>c,I95>T|300^301>ins^t#|303^304>ins^agg|g327>c,L109>F|
26 26/OR9-2 P (1) V26/OR9-2*01 AF029308   t22  ,S8  |
P (1) V26/OR9-2*02 AL356489   t22>c,S8>P|
29 29/OR9-2 ORF V29/OR9-2*01 L05150   c148  ,L50  |
ORF V29/OR9-2*02 AF029308   c148>g,L50>V|

IMGT note:
(1)
 In frame STOP-CODON.
(2)
 No INIT-CODON: ATG is replaced by AGG. AF029308 being longer than L05151, and therefore showing the defect, has been selected as reference sequence (IMGT annotation 28/05/2009).
(3)
 No INIT-CODON: ATG is replaced by ACG.

Created: 21/06/99
Last updated: 28/05/09
Authors: Géraldine Folch, Fatena Bellahcene