IMGT Repertoire (IG and TR)


Locus representation: Bovine (Bos taurus) TRG locus on chromosome 4 (4q3.1 and 4q1.5-2.2)

In cattle (bovine, Bos taurus) and sheep (ovine, Ovis aries), the TRG genes are organized in two separate loci on chromosome 4:

Bovine (Bos taurus) TRG locus on chromosome 4 (4q3.1 and 4q1.5-2.2)

Locus representation bovine TRG

Legend:
Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.
A double slash // indicates a gap in genome assembly. Distances in bp (base pair) or in kb (kilobase) associated with a double slash are taken into account in the length of the lines and included in the numbers displayed at the right end of the lines.
A dotted line ... indicates the distance in kb (kilobase) between the locus and its bornes (5' borne and the most 5' gene in the locus and/or 3' borne and the most 3' gene in the locus) on the top and bottom lines, respectively. These distances are not represented at scale and/or are not included in IMGT-LOCUS-UNIT and may not be included in the numbers displayed at the right ends of these two lines .

Arrows indicate the TRGC cassettes and the transcriptional orientation of their genes.

* In AY644518 TRGV5-2 is rearranged with TRGJ2-1 and TRGV6-2 is rearranged with TRGJ6-1.

Locus representation with only the functional genes: Bovine (Bos taurus) TRG locus on chromosome 4 (4q3.1 and 4q1.5-2.2)

Locus representation bovine TRG

* When needed, indicate the presence of allele(s) with another functionality: see above Bovine (Bos taurus) TRG locus on chromosome 4 (4q3.1 and 4q1.5-2.2)

IMGT references:
  1. [1] Ishiguro, N. et al., Immunogenetics, 38, 437-443 (1993). PMID:8406615
  2. [2] Hein, W. R. et al., Immunology, 91, 58-64 (1997). PMID:9203966
  3. [3] Lahmers, K.K. et al., J. Leukoc. Biol., 77, 199-208 (2005). PMID:15522917
  4. [4] Herzig, C. et al., Immunogenetics, 58, 138-151 (2006). PMID:16541255
  5. [5] Conrad, M. et al., Vet. Immunol. Immunopathol.,115, 346-356 (2007). PMID:17141331
Created:
25/06/2009
Last updated:
22/09/2023
Authors:
Joumana Jabado Michaloud and Marie-Paule Lefranc