Channel catfish (Ictalurus punctatus) IGH locus
Legend:
Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.
A double slash // indicates a gap in genome assembly. Distances in bp (base pair) or in kb (kilobase) associated with a double slash are taken
into account in the length of the lines and included in the numbers displayed at the right end of the lines.
A dotted line ... indicates the distance in kb (kilobase) between the locus and its bornes (5' borne and the most 5' gene in the locus and/or 3'
borne and the most 3' gene in the locus) on the top and bottom lines, respectively. These distances are not represented at scale and/or are not
included in IMGT-LOCUS-UNIT and may not be included in the numbers displayed at the right ends of these two lines
.
not sequenced genes.
There are two clusters containing IGHV, IGHD, IGHJ and IGHC (IGHM and IGHD) genes (Greg Warr, personnal communication 13/06/2002).
The IGHV genes belong to seven different subgroups.
The IGHV gene number and organization are not known but the average distance between genes is about 3 kb.
IMGT references:
- [1] Ventura-Holman, T. and Lobb, C.J., Mol. Immunol., 38, 557-564 (2001).
- [2] Ghaffari, S.H. and Lobb, C.J., J. Immunol., 162, 1519-1529 (1999).
IGHV genes
- [3] Ghaffari, S.H. and Lobb C.J., J. Immunol., 143, 2730-2739 (1989).
- [4] Ghaffari, S.H. and Lobb C.J., J. Immunol., 146, 1037-1046 (1991).
- [5] Warr, G.W. et al., Eur. J. Immunol., 18, 393-397 (1991).
- [6] Ventura-Holman, T. et al., Mol. Immunol., 31, 823-832 (1994).
- [7] Ventura-Holman, T. et al., Eur. J. Immunogenet., 23, 7-14 (1996).
- [8] Wilson, M. et al., Proc. Natl. Acad. Sci. USA, 94, 4593-4597 (1997).
- [9] Ghaffari, S.H. and Lobb, C.J., J. Immunol., 162, 1519-1529 (1999).
- [10] Hayman, J.R. and Lobb C.J., J. Immunol., 164, 1916-1924 (2000).
IGHD genes
- [11] Ghaffari, S.H. and Lobb, C.J., J. Immunol., 162, 1519-1529 (1999).
- [12] Hayman, J.R. and Lobb, C.J., J. Immunol., 164, 1916-1924 (2000).
IGHJ genes
- [13] Hayman, J.R. et al., J. Immunol., 151, 3587-3596 (1993).
- [14] Ghaffari, S.H. and Lobb C.J., Mol. Immunol., 29, 151-159 (1992).
- [15] Ghaffari, S.H. and Lobb, C.J., J. Immunol., 162, 1519-1529 (1999).
IGHC genes
- [16] Magor, B.G. et al., J. Immunol., 153, 5556-5563 (1994).
- [17] Wilson, L. et al., Proc. Natl. Acad. Sci. USA, 94, 4593-4597 (1997).
- [18] Ghaffari, S.H. and Lobb, C.J., J. Immunol., 162, 1519-1529 (1999).
- [19] Bengten, E. et al., Unpublished (2001).