IMGT Repertoire (IG and TR)

Locus representation: Sheep (Ovis aries) TRG locus on chromosome 4 (4q3.1 and 4q2.1)

In cattle (bovine, Bos taurus) and sheep (ovine, Ovis aries), the TRG genes are organized in two loci on chromosome 4:

The TRG1 locus at 4q3.1 is syntenic to the human TRG locus at 7p14, whereas the TRG2 locus at 4q2.2 is a peculiarity of the cattle and sheep.

Sheep (Ovis aries) TRG locus on chromosome 4 (4q3.1 and 4q2.1)

Locus representation sheep TRG

Legend:
Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.
A double slash // indicates a gap in genome assembly. Distances in bp (base pair) or in kb (kilobase) associated with a double slash are taken into account in the length of the lines and included in the numbers displayed at the right end of the lines.
A dotted line ... indicates the distance in kb (kilobase) between the locus and its bornes (5' borne and the most 5' gene in the locus and/or 3' borne and the most 3' gene in the locus) on the top and bottom lines, respectively. These distances are not represented at scale and/or are not included in IMGT-LOCUS-UNIT and may not be included in the numbers displayed at the right ends of these two lines .

Arrows indicate the TRGC cassettes and the transcriptional orientation of their genes.

Locus representation with only the functional genes: Sheep (Ovis aries) TRG locus on chromosome 4 (4q3.1 and 4q2.1)

Locus representation sheep TRG

* When needed, indicate the presence of allele(s) with another functionality: see above Sheep (Ovis aries) TRG locus on chromosome 4 (4q3.1 and 4q2.1)

IMGT references:
  1. [1] Vaccarelli, G. et al., Gene, 357, 103-114 (2005). PMID:16125878
  2. [2] Miccoli, M. C. et al., J. Mol. Evol., 57, 52-62 (2003). PMID:12962306
  3. [3] Vaccarelli, G. et al., BMC Genomics., 9:81 (2008). PMID:18282289
Created:
19/10/2006
Last updated:
22/09/2023
Authors:
Yan Wu and Marie-Paule Lefranc