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In cattle (bovine, Bos taurus) and sheep (ovine, Ovis aries), the TRG genes are organized in two loci on chromosome 4:

The TRG1 locus at 4q3.1 is syntenic to the human TRG locus at 7p14, whereas the TRG2 locus at 4q2.2 is a peculiarity of the cattle and sheep.

Sheep (Ovis aries) TRG locus on chromosome 4 (4q3.1 and 4q2.1)

Locus representation sheep TRG

Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.
A double slash // indicates a gap in genome assembly. Distances in bp (base pair) or in kb (kilobase) associated with a double slash are taken into account in the length of the lines and included in the numbers displayed at the right end of the lines.
A dotted line ... indicates the distance in kb (kilobase) between the locus and its bornes (5' borne and the most 5' gene in the locus and/or 3' borne and the most 3' gene in the locus) on the top and bottom lines, respectively. These distances are not represented at scale and are not included in the numbers displayed at the right ends of these two lines.

Arrows indicate the TRGC cassettes and the transcriptional orientation of their genes.

Locus representation with only the functional genes: Sheep (Ovis aries) TRG

Locus representation sheep TRG

* When needed, indicate the presence of allele(s) with another functionality: see above Sheep (Ovis aries) TRG locus

IMGT references:
  1. [1] Vaccarelli, G. et al., Gene, 357, 103-114 (2005). PMID:16125878
  2. [2] Miccoli, M. C. et al., J. Mol. Evol., 57, 52-62 (2003). PMID:12962306
  3. [3] Vaccarelli, G. et al., BMC Genomics., 9:81 (2008). PMID:18282289
Last updated:
Yan Wu and Marie-Paule Lefranc