IMGT Repertoire (RPI)

IMGT Collier de Perles for Norway rat CD8A (V-LIKE-DOMAIN)

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CD8 alpha chain (P07725)
CDR-IMGT lengths: [6.2.9]

Collier CD8A V-LIKE-DOMAIN

This figure has been generated with the IMGT/Collier de Perles tool initially implemented by Gérard Mennessier (LPM, Montpellier, France, 25/05/1997) and further developed by Manuel Ruiz (08/09/1999) and Quentin Kaas (15/11/2001).

Legend:

Amino acids are shown in the one-letter abbreviation.
Hydrophobic amino acids (hydropathy index with positive value) and Tryptophan (W) found at a given position in more than 50 % of analysed Ig and TcR sequences are shown in blue.
All Proline (P) are shown in yellow.
Arrows indicate the direction of the beta sheets and their different designations in 3D structure. This information has to be used carefully if not supported by experimental data.
Hachured circles or squares correspond to missing positions according to the IMGT unique numbering.
Missing positions in IMGT Colliers de Perles based on 3D structures may be due to incomplete experimental data.
The CDR-IMGT are limited by amino acids shown in squares, which belong to the neighbouring FR-IMGT.

IMGT note:

3D structure is needed to confirm that the five amino acids between 46 and 47 "SSELL" belongs to an extended CC' beta turn by homology with the four additional amino acids of the human CD8A CC' beta turn (PDB: 1cd8 and Collier de Perles: Human CD8A).

See also:

IMGT Repertoire:
- IMGT Collier de Perles for Norway rat CD8B (V-LIKE-DOMAIN)
IMGT Scientific chart:
- Collier de Perles is described using the IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN
- Definition of the FR-IMGT and CDR-IMGT regions
IMGT Index:
- IMGT Colliers de perles
IMGT Education (FR):
- La superfamille des immunoglobulines (IgSF)
Tools: