Here you are: IMGT Web resources > IMGT Scientific chart > 2. Numbering

Correspondence between V numberings

Correspondence between numberings for CDR of different lengths (horizontal display)
(without gaps, without correspondence)

Click here for:

CDR1-IMGT

There are no gaps and therefore no correspondence between the numberings shown in this table.

Brackets indicate the limits of the CDR in each numbering.
Click on the protein name for the CDR1-IMGT 3D structure.
For more information on the proteins, see Protein with known 3D structures Identification and Colliers de Perles: Human Immunoglobulins 


IMGT                      FR1-IMGT                     CDR1-IMGT                     FR2-IMGT
unique               C                                                                       W
numbering [1]        23  24  25  26 [27  28  29  30  31  32  33  34  35  36  37  38] 39  40  41
                                                                                                                      CDR       CDR1-
                                                                                                                     length[2]  IMGT[1]
IGHV  [2]            22  23  24  25  26  27  28  29  30 [31  32  33  34  35          35A 35B]36                        7          10
                     22  23  24  25  26  27  28  29  30 [31  32  33  34              35  35A]36                        6           9
                     22  23  24  25  26  27  28  29  30 [31  32  33                  34  35 ]36                        5           8

                                                                                                      H1"canonical    H1        CDR1-      Example
                                                                                                      structure"     length[5]  IMGT[1]    of proteins

IGHV  [5]            22  23  24  25 [26  27  28  29  30  31  31a 31b 32] 33          34  35  36           3            9          10
      [5]            22  23  24  25 [26  27  28  29  30  31  31a 32] 33              34  35  36           2            8           9
  [3] [4] [5]        22  23  24  25 [26  27  28  29  30  31  32] 33                  34  35  36           1            7           8       Kol, Newm,
                                                                                                                                           McPC603, J539






IMGT                      FR1-IMGT                      CDR1-IMGT                    FR2-IMGT
unique               C                                                                       W
numbering [1]        23  24  25  26 [27  28  29  30  31  32  33  34  35  36  37  38] 39  40  41                        CDR       CDR1-
                                                                                                                      length[2]  IMGT[1]

IGKV [2]             23 [24  25  26  27  27A 27B 27C 27D 27E 27F 28  29  30  31  32  33  34] 35                        17         12
                     23 [24  25  26  27  27A 27B 27C 27D 27E 28  29  30  31  32      33  34] 35                        16         11
                     23 [24  25  26  27  27A 27B 27C 27D 28  29  30  31  32          33  34] 35                        15         10
                     23 [24  25  26  27  27A 28  29  30  31  32                      33  34] 35                        12          7
                     23 [24  25  26  27  28  29  30  31  32                          33  34] 35                        11          6
                     23 [24  25  26  27  29  30  31  32                              33  34] 35                        10          5

                                                                                                      L1"canonical    L1        CDR1-      Example
                                                                                                      structure"     length[5]  IMGT[1]    of proteins

IGKV [3] [4]         23  24  25 [26  27  28  29  30  31  31a 31b 31c 31d 31e 31f 32] 33  34  35            3           13         12       McPC603
                     23  24  25 [26  27  28  29  30  31  31a 31c 31d 31e 31f 32]     33  34  35            4           12         11       4-4-20
                     23  24  25 [26  27  28  29  30  31  32]                         33  34  35            2            7          6       Rei
                     23  24  25 [26  27  28  29  30  32]                             33  34  35            1            6          5       J539


IGKV [5]             23  24  25 [26  27  28  29  30  30a 30b 30c 30d 30e 30f 31  32] 33  34  35            3           13         12       McPC603
                     23  24  25 [26  27  28  29  30  30a 30b 30c 30e 30f 31  32]     33  34  35            4           12         11       4-4-20
                     23  24  25 [26  27  28  29  30  30a 30b 30c 30d 31  32]         33  34  35            5           11         10
                     23  24  25 [26  27  28  29  30  30a 31  32]                     33  34  35            6            8          7
                     23  24  25 [26  27  28  29  30  31  32]                         33  34  35            2            7          6       Rei
                     23  24  25 [26  27  28  29  30  32]                             33  34  35            1            6          5       J539






IMGT                      FR1-IMGT                      CDR1-IMGT                    FR2-IMGT
unique               C                                                                       W
numbering [1]        23  24  25  26 [27  28  29  30  31  32  33  34  35  36  37  38] 39  40  41                        CDR       CDR1-
                                                                                                                      length[2]  IMGT[1]

IGLV [2]             23 [24  25  26  27  27A 27B 27C 28  29  30  31  32              33  34] 35                        14          9
                     23 [24  25  26  27  27A 27B 28  29  30  31  32                  33  34] 35                        13          8
                     23 [24  25  26  27  27A 28  29  30  31  32                      33  34] 35                        12          7
                     23 [24  25  26  27  28  29  30  31  32                          33  34] 35                        11          6

                                                                                                       L1"canonical    L1        CDR1-     Example
                                                                                                       structure"     length[3]  IMGT[1]   of proteins

IGLV [3]             23  24  25 [26  27  28  29  30  30a 30b 30c 31  32]             33  34  35                        10          9       Newm
                     23  24  25 [26  27  28  29  30  30a 30b 31  32]                 33  34  35                         9          8       Kol, Rhe

                                                                                                                       L1
                                                                                                                      length[5]

     [5]             23  24 [25  26  27  28  29  30  30a 30b 30c 31  32]             33  34  35            2,3         11          9       Newm
                     23  24 [25  26  27  28  29  30  30a 30b 31  32]                 33  34  35            1           10          8       Kol, Rhe
                     23  24 [25  26  27  30  30a 30b 30c 31  32]                     33  34  35            4            9          7       Hil
References:
[1] Lefranc, M.-P., The Immunologist, 7, 132-136 (1999).
[2] Kabat, E.A. et al., In: Sequences of Proteins of Immunological Interest, NIH Publication, 91-3242 (1991).
[3] Chothia, C. and Lesk, A.M., J. Mol. Biol., 196, 901-917 (1987).
[4] Chothia, C. et al., Nature, 342, 877-883 (1989).
[5] Al-Lazikani, B. et al., J. Mol. Biol., 273, 927-948 (1997).