3D representation
IMGT 3D representations of immunoglobulin (IG), T cell receptor (TR) and major histocompatibility (MH) domains are available from the IMGT Repertoire. This visualization permits a correlation between 2D representations (IMGT Colliers de Perles) and 3D structures (IMGT/3Dstructure-DB).
Structural data are retrieved from PDB and from the literature. The IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN [1,2], the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN, the IMGT unique numbering for G-DOMAIN and G-LIKE-DOMAIN and the IMGT standardization rules of the IMGT Scientific chart have been applied to sequence and 3D structure data from PDB. IMGT/3Dstructure-DB database [3] provides the first common access to annotated structural data concerning IG, TR and MH, according to IMGT-ONTOLOGY.
Click here for Correspondence between labels for IG and TR domains in IMGT/3Dstructure-DB and IMGT/LIGM-DB.
| [1] | Lefranc, M.-P., The Immunologist, 7, 132-136 (1999) LIGM:217 |
| [2] | Lefranc, M.-P., et al., Dev. Comp. Immunol., 27, 55-77 (2003) PMID: 12477501, LIGM:268 |
| [3] | Kaas, Q. et al., Nucl. Acids Res., 32, D208-D210 (2004) PMID: 14681396, LIGM:281 |