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3D representation

IMGT 3D representations of immunoglobulin (IG), T cell receptor (TR) and major histocompatibility (MH) domains are available from the IMGT Repertoire. This visualization permits a correlation between 2D representations (IMGT Colliers de Perles) and 3D structures (IMGT/3Dstructure-DB).

Structural data are retrieved from PDB and from the literature. The IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN [1,2], the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN, the IMGT unique numbering for G-DOMAIN and G-LIKE-DOMAIN and the IMGT standardization rules of the IMGT Scientific chart have been applied to sequence and 3D structure data from PDB. IMGT/3Dstructure-DB database [3] provides the first common access to annotated structural data concerning IG, TR and MH, according to IMGT-ONTOLOGY.

Click here for Correspondence between labels for IG and TR domains in IMGT/3Dstructure-DB and IMGT/LIGM-DB.

[1] Lefranc, M.-P., The Immunologist, 7, 132-136 (1999) LIGM:217
[2] Lefranc, M.-P., et al., Dev. Comp. Immunol., 27, 55-77 (2003) PMID: 12477501, LIGM:268
[3] Kaas, Q. et al., Nucl. Acids Res., 32, D208-D210 (2004) PMID: 14681396, LIGM:281