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TR γδ G115 (PDB: 1hxm_B)

IMGT/3Dstructure-DB card: 1hxm

The TRGC1 C-DOMAIN is shown in two different orientations.

Side view (backbone model)


A C-DOMAIN corresponds to the complete C-REGION, to most of the C-REGION, or to part of the C-REGION, depending on the immunoglobulin or T cell receptor chain type.
This figure shows the C-DOMAIN of a gamma chain (PDB: 1hxm_B) of a gamma-delta T cell receptor in two different orientations. Only the C-GAMMA, part of the TRG C-REGION, is displayed. The carbohydrates are not shown.
In the PDB file, the sequence includes 10 amino acids of the CONNECTING-REGION of the gamma chain, however, the 3D structure only includes C-GAMMA amino acids up to position 124 (according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN).
The strands C, F and G are on the external face of C-GAMMA. Strands A, B , D and E are on the interface with the C-DELTA in the gamma-delta T cell receptor.


This image has been generated with the program RASMOL version 2.6 [1] from the PDB file 1hxm [2], containing the atomic coordinates of the crystal structure of a human Vgamma9/Vdelta2 T cell receptor.

See also:

[1] Sayle, R. and Milner-White, E.J. TIBS, 20, 374 (1995).
[2] Allison, T.J. et al., Nature, 411, 820-824 (2001).