IMGT Repertoire (IG and TR)

Collier de Perles: human (Homo sapiens) RPI-MH1Like

MICA*01 C-LIKE (AL845443)

Polymorphisms:

  • MICA*03 (U56942): S 27, R 35, T 40, G 117
  • MICA*04 (X92841): S 27, R 35, T 40
  • MICA*05 (U56944): S 27, R 35, T 40, R 93
  • MICA*06 (AF336065): S 27, R 35, T 40
  • MICA*08 (BX119958): S 27, R 35, I 38, T 40, R 93
  • MICA*09 (AK225393): S 27, R 35, T 40
  • MICA*10 (AF336071): S 27, R 35, I 38, T 40, R 93
  • MICA*11 (AF336073): A 120
  • MICA*13 (U56952): R 93
  • MICA*16 (AF336075): S 27, R 35, I 38, T 40, L 45.1, R 93
  • MICA*19 (AF336079): S 27, R 35, I 38, T 40, R 93
  • MICA*22 (Y16804): S 27, R 35, I 38, T 40, R 93
  • MICA*24 (Y16807): S 27, R 35, T 40
  • MICA*27 (AJ250802): S 27, R 35, I 38, T 40, R 93
  • MICA*30 (AF079424): A 120
  • MICA*33 (AJ250505): S 27, R 35, I 38, T 40, R 93
  • MICA*34 (AF011849): S 27, R 35, T 40
  • MICA*35 (AF011852): S 27, R 35, I 38, T 40, R 93
  • MICA*37 (AF011864): S 27, R 35, I 38, T 40, R 93
  • MICA*38 (AF011867): S 27, R 35, T 40
  • MICA*39 (AF011870): S 27, R 35, I 38, T 40, L 45.1, R 93
  • MICA*42 (AF106637): S 27, R 35, I 38, T 40, R 93
  • MICA*43 (AJ250991): S 101
  • MICA*44 (AF106643): S 27, R 35, T 40
  • MICA*45 (AJ250507): E 93
  • MICA*46 (AJ250502): C 31
  • MICA*47 (AJ295251): A 120
  • MICA*48 (AF264742): S 27, R 35, I 38, T 40, R 93
  • MICA*49 (AF264746): S 27, R 35, T 40
  • MICA*54 (AJ250500): S 27, R 35, I 38, T 40, R 93
  • MICA*55 (AF106655): S 27, R 35, I 38, T 40, R 93
  • MICA*56 (AY029762): S 27, R 35, T 40
  • MICA*59 (AF411925): S 27, R 35, I 38, T 40
  • MICA*61 (AF302792): S 27, R 35, I 38, T 40, R 93, A 99
  • MICA*62 (AF303446): S 27, R 35, T 40, R 93
  • MICA*63 (AF305055): S 27, R 35, I 38, R 93
  • MICA*64 (AF305056): G 93
  • MICA*66 (Y16811): S 27, R 35, I 38, T 40, R 93
  • MICA*67 (Y18113): S 27, R 35, T 40
  • MICA*68 (Y18114): S 27, R 35, I 38, T 40, R 93
  • MICA*70 (Y18116): S 27, R 35, I 38, T 40, R 93
  • MICA*72 (Y18118): T 40
  • MICA*74 (AL645933): S 27, R 35, I 38, T 40, R 93
  • MICA*75 (EU369697): S 27, R 35, I 38, T 40, R 93
  • MICA*76 (EU365393): S 27, R 35, I 38, T 40, R 93
  • MICA*77 (EU365394): S 27, R 35, T 40
  • MICA*78 (AJ871399): S 27, R 35, I 38, T 40, R 93
  • MICA*79 (AM899996): S 27, R 35, I 38, T 40, R 93, G 117
  • MICA*80 (AM944063): S 27, R 35, I 38, T 40, S 80, R 93
  • MICA*87 (AL669854): S 27, R 35, I 38, T 40, R 93

On one layer

On two layers

Colors are according to IMGT Color menu for sequence alignments and Color menu for CDR-IMGT

Legend:
  • Amino acids are shown in the one-letter abbreviation.
  • Hydrophobic amino acids (hydropathy index with positive value) and Tryptophan (W) found at a given position in more than 50% of analysed IG and TR sequences are shown in blue.
  • All Proline (P) are shown in yellow.
  • Missing positions in IMGT Colliers de Perles based on 3D structures may be due to incomplete experimental data.
  • Arrows indicate the direction of the beta sheets and their different designations in 3D structures. This information has to be used carefully if not supported by experimental data.
  • The positions 26, 39 and 104 are shown in squares by homology with the corresponding positions in the V-REGIONs. Positions 45 and 77 which delimit the characteristic "CD" strand of the C-DOMAINs, and position 118 which corresponds structurally to J-PHE or J-TRP of the J-REGION, are also shown in squares.
  • Hatched circles or squares correspond to missing positions according to the IMGT unique numbering for C-DOMAINs (Lefranc et al. 2005 PMID: 15572068 PDF).
  • In green, position of amino acid changes involved in allotype polymorphism.
  • Strands of the beta-pleated sheet localized at the interface between domains are shown in bold.
  • The hinge six amino acids which belongs to the same exon as the CH2 domain are not shown.
  • The CHS region is not shown.
See also:
Created:
23/02/2011
Last updated:
Wednesday, 23-Oct-2024 09:53:41 CEST
Authors:
François Ehrenmann, Chantal Ginestoux and Patrice Duroux