Provisional nomenclature (scaffolds only, no chromosome assembly).
Naked mole-rat (Heterocephalus glaber) TRD locus
- The Naked mole-rat (Heterocephalus glaber) TRD locus.
The orientation of the locus is reverse (REV).
- The Naked mole-rat (Heterocephalus glaber) TRA/TRD locus spans 762 kilobases (kb),
from 10 kb upstream of the most 5' gene in the locus, TRAV43-1 (F), to 10 kb
downstream of the most 3' gene in the locus, TRAC (F).
The Locus representation
encompasses 800 kb including the 3' borne DAD1.
- The Naked mole-rat (Heterocephalus glaber) TRD locus consists of 5
TRDV genes belonging to 5 TRDV subgroups, 3 TRDD, 4 TRDJ segments and 1 TRDC
gene.
- The TRDV genes span 294
kilobases (kb), the TRDJ genes span 113
kilobases (kb), the TRDD genes span 35
kilobases (kb), the TRDC genes span 6
kilobases (kb)
Clusters
- The TRDV genes are localized in 2 V-CLUSTER:
- the 5' V-CLUSTER, classically in 5' of the TRDD, TRDJ and
TRDC, includes 12 TRDV genes belonging to 8 subgroups (4 genes
are functional, 1 is ORF and 7 genes are pseudogene).
- the 3' V-CLUSTER, downstream of the TRDC in inverted
orientation, includes 1 TRDV gene (ORF).
- The TRDD, TRDJ and TRDC genes are localized in one
D-J-C-CLUSTER between the 5' V-CLUSTER and the 3' V-CLUSTER:
- The CLUSTER includes 3 TRDD genes belonging to 2
subgroups functional, 4 TRDJ (1 gene is functional, 2 genes are ORF and 1 gene is pseudogene) and 1 TRDC functional.
More information:
Gene table: Naked mole-rat (Heterocephalus glaber) TRDV
Gene table: Naked mole-rat (Heterocephalus glaber) TRDD
Gene table: Naked mole-rat (Heterocephalus glaber) TRDJ
Gene table: Naked mole-rat (Heterocephalus glaber) TRDC
Potential germline repertoire: Naked mole-rat (Heterocephalus glaber) TRDV, TRDD and TRDJ genes
Locus description: Naked mole-rat (Heterocephalus glaber) TRA
See also:
Genomic orientation (IMGT Index)
Taxonomy: Eutheria