House mouse (Mus musculus) IGHV genes
The house mouse (
Mus musculus) IGH locus on chromosome 12 comprises 356 IGHV genes belonging to 16 IGHV subgroups:
IMGT group |
IMGT subgroup |
Functional |
ORF |
Pseudogene |
Total |
IGHV |
IGHV1 |
106(+6)* |
4(+1)* |
57(37:20) (+5(5:0))* |
173 |
IGHV2 |
21(+1)* |
0 |
3(1:2) (+1(1:0))* |
25 |
IGHV3 |
7(+2)* |
0 |
1(1:0) (+2(1:1))* |
10 |
IGHV4 |
1(+1*) |
0 |
(1(1:0))* |
2 |
IGHV5 |
26 |
0 |
27(2:25) |
53 |
IGHV6 |
6 |
2 |
3(0:3) |
11 |
IGHV7 |
3 |
(1)* |
(+1(0:1))* |
4 |
IGHV8 |
5(+2)* |
3(+2)* |
13(6:7) (+1(1:0))* |
23 |
IGHV9 |
8 |
0 |
0 |
8 |
IGHV10 |
4 |
0 |
3(0:3) |
7 |
IGHV11 |
2 |
0 |
0 |
2 |
IGHV12 |
2 |
1 |
4(3:1) |
7 |
IGHV13 |
1 |
(+1)* |
(+1(1:0))* |
2 |
IGHV14 |
4(+1)* |
0 |
(+1(1:0))* |
5 |
IGHV15 |
1 |
0 |
1(0:1) |
2 |
IGHV16 |
0 |
1 |
0 |
1 |
IGHV(I) |
0 |
0 |
2(0:2) |
2 |
IGHV(II) |
0 |
0 |
5(0:5) |
5 |
IGHV(III) |
0 |
0 |
14(0:14) |
14 |
Total |
197(+13)* |
13(+5)* |
132(+13)* |
356 |
In the column 'Pseudogene', the number of pseudogenes with V-REGION in-frame and the number of pseudogenes with frameshift(s) are shown separated by two dots, between parentheses.
* An asterisk indicates that the following gene has alleles with different functionalities:
- FUNCTIONAL or PSEUDOGENE (IGHV1-42, IGHV1-58, IGHV1S30, IGHV1S65, IGHV1S112, IGHV2-7, IGHV3-2, IGHV3-3, IGHV4-2, IGHV14-2).
- FUNCTIONAL or ORF (IGHV1-62-3, IGHV8-5).
- ORF or PSEUDOGENE (IGHV7-2, IGHV13-1)
- FUNCTIONAL, ORF or PSEUDOGENE (IGHV8-9).
House mouse (Mus musculus) IGHD genes
The house mouse (
Mus musculus) IGH locus on chromosome 12 comprises 34 IGHD genes belonging to 6 IGHD subgroups:
IMGT group |
IMGT set or subgroup (if any) |
Functional |
ORF |
Pseudogene |
Total |
IGHD |
IGHD1 |
3 |
0 |
0 |
3 |
IGHD2 |
14 |
0 |
0 |
14 |
IGHD3 |
3 |
0 |
0 |
3 |
IGHD4 |
1 |
0 |
0 |
1 |
IGHD5 |
0 |
6 |
1 |
7 |
IGHD6 |
5 |
1 |
0 |
6 |
Total |
26 |
7 |
1 |
34 |
House mouse (Mus musculus) IGHJ genes
The house mouse (
Mus musculus) IGH locus on chromosome 12 comprises 4 IGHJ genes:
IMGT group |
IMGT set or subgroup (if any) |
Functional |
ORF |
Pseudogene |
Total |
IGHJ |
IGHJ1 |
1 |
0 |
0 |
1 |
IGHJ2 |
1 |
0 |
0 |
1 |
IGHJ3 |
(1)* |
0 |
(1)* |
1 |
IGHJ4 |
1 |
0 |
0 |
1 |
Total |
3(+1)* |
0 |
(1)* |
4 |
* An asterisk indicates that the following gene has alleles with different functionalities:
- FUNCTIONAL or PSEUDOGENE (IGHJ3).
More information:
Gene table: house mouse (Mus musculus) IGHV
Gene table: house mouse (Mus musculus) IGHD
Gene table: house mouse (Mus musculus) IGHJ
Locus description: house mouse (Mus musculus) IGH