Rabbit (Oryctolagus cuniculus) TRB locus

Legend:
Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.
A double slash // indicates a gap in genome assembly. Distances in bp (base pair) or in kb (kilobase) associated with a double slash are taken into account in the length of the lines and included in the numbers displayed at the right end of the lines.
A dotted line ... indicates the distance in kb (kilobase) between the locus and its bornes (5' borne and the most 5' gene in the locus and/or 3' borne and the most 3' gene in the locus) on the top and bottom lines, respectively. These distances are not represented at scale and/or are not included in IMGT-LOCUS-UNIT and may not be included in the numbers displayed at the right ends of these two lines .

TRB gene names are according to the IMGT nomenclature [1].
Single arrows show genes whose polarity is opposite to that of the D-J-C-CLUSTER comprising TRBD1-TRBJ (J1-1 to J1-6)-TRBC1-TRBD2-TRBJ (J2-1 to J2-6)-TRBC2.

The rabbit (Oryctolagus cuniculus) Locus representation is Fig. 4 modified from: R. Antonacci, F. Giannico, S. Ciccarese, S. Massari.
Genomic characteristics of the T cell receptor (TRB) locus in the rabbit (Oryctolagus cuniculus) revealed by comparative and phylogenetic analyses.
Immunogenetics. 66:255-266 (2014). doi: 10.1007/s00251-013-0754-1. PMID: 24500788

The original figure was kindly provided by Salvatrice Ciccarese with permission from Springer.

Zoom for TRB D-J-C-CLUSTER

• Gene table: rabbit (Oryctolagus cuniculus) TRBV
• Gene table: rabbit (Oryctolagus cuniculus) TRBD
• Gene table: rabbit (Oryctolagus cuniculus) TRBJ
• Gene table: rabbit (Oryctolagus cuniculus) TRBC
• Potential germline repertoire: rabbit (Oryctolagus cuniculus) TRBV, TRBD and TRBJ genes

• Genomic orientation (IMGT Index)
• Taxonomy: Eutheria