Here you are: IMGT Web resources > IMGT Repertoire (IG and TR) > 1. Locus and genes

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

The 19 House mouse (Mus musculus) IGKV subgroups belong to three clans (Figure IGKV clans). Clans comprise, respectively:

See also Germline gene and allele table: Mouse (Mus musculus) IGHV anterior to November 2000.

IMGT subgroup IMGT gene name IMGT allele name Fct Chromosomal localization R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGKV1 IGKV1-35 IGKV1-35*01 ORF (18) 6 (30.0 cM) C3H cu2 MAP AJ231200 [31-34]
IGKV1-88 IGKV1-88*01 F 6 (30.0 cM) + + C57BL/6 cs1 MAP AJ231206 [31-34]
IGKV1-99 IGKV1-99*01 F 6 (30.0 cM) + + C3H cv1 MAP AJ231207 [31-34]
IGKV1-108 IGKV1-108*01 P (1) 6 (30.0 cM) C3H cq1 MAP AJ231204 [31-34]
IGKV1-110 IGKV1-110*01 F 6 (30.0 cM) + + + BALB/c K5.1 MAP D00080 [14] M15566 BALB/c V-1A MAP M28131 [19]
C57BL/6 bb1 MAP AJ231201 [31-34]
IGKV1-110*02 (47) F 6 (30.0 cM) + + + NZB/BINJ V-1B MAP M28132 [19]
IGKV1-115 IGKV1-115*01 P (2) 6 (30.0 cM) C3H cz1 MAP AJ231208 [31-34]
IGKV1-117 IGKV1-117*01 F 6 (30.0 cM) + + + BALB/c K1A5 MAP D00081 [14] BALB/c M15567 [14]
V-1C MAP M28133 [19]
C3H cr1 MAP AJ231205 [31-34]
IGKV1-117*02 F 6 (30.0 cM) + + CE/J V-1Cf MAP M28134 [19]
IGKV1-122 IGKV1-122*01 F 6 (30.0 cM) + + + BALB/c K18.1 MAP D00082 [14] BALB/c M15568 [14]
C57BL/6 bl1 MAP AJ231203 [31-34]
IGKV1-131 IGKV1-131*01 ORF (17) 6 (30.0 cM) C57BL/6 bh2 MAP AJ231197 [31-34]
IGKV1-132 IGKV1-132*01 F 6 (30.0 cM) + + C57BL/6 bi2 MAP AJ231198 [31-34]
IGKV1-133 IGKV1-133*01 F 6 (30.0 cM) + + + 129/Sv 70/1 MAP Z72382 [27] C57BL/6 bj2 MAP AJ231199 [31-34]
IGKV1-135 IGKV1-135*01 F 6 (30.0 cM) + + + 129/Sv 70/3 MAP Z72384 [27] C57BL/6 bd2 MAP AJ231196 [31-34]
IGKV1-136 IGKV1-136*01 P (3) 6 (30.0 cM) C57BL/6 bc1r MAP AJ231202 [31-34]
IGKV2 IGKV2-93-1 IGKV2-93-1*01 P 6 (30.0 cM) - - - C3H hh24r MAP AJ231265 [34]
IGKV2-95-1 IGKV2-95-1*01 P 6 (30.0 cM) - - - C57BL/6 hb24r MAP AJ231261 [34]
IGKV2-95-2 IGKV2-95-2*01 P 6 (30.0 cM) - - - C57BL/6 hi24r MAP AJ231266 [34]
IGKV2-105 IGKV2-105*01 P (4) 6 (30.0 cM) C3H hd24 MAP AJ231262 [31-34]
IGKV2-107 IGKV2-107*01 P (5) 6 (30.0 cM) C3H hc24 MAP AJ132682 [31-34]
IGKV2-109 IGKV2-109*01 F 6 (30.0 cM) + + + C3H he24 MAP AJ132683 [31-34]
IGKV2-109*02 (48) F 6 (30.0 cM) + + BALB/c 24B MAP K02418 [9]
IGKV2-109*03 (65) F 6 (30.0 cM) CaV24B-1 MAP M80409 [25]
IGKV2-109*04 (65) F 6 (30.0 cM) CaV24B0 MAP M80410 [25]
IGKV2-112 IGKV2-112*01 F 6 (30.0 cM) + + BALB/c 167 J00562 [6] BALB/c 24 MAP K02415 [9]
C3H hg24 MAP AJ231264 [31-34]
IGKV2-112*02 (65) F 6 (30.0 cM) CaV24 MAP M80407 [25]
IGKV2-113 IGKV2-113*01 P (6) 6 (30.0 cM) C57BL/6 ha24 MAP AJ231260 [31-34]
IGKV2-116 IGKV2-116*01 P (7) 6 (30.0 cM) C57BL/6 hk24 MAP AJ277843 [31-34]
IGKV2-137 IGKV2-137*01 F 6 (30.0 cM) + + + C3H hf24 MAP AJ231263 [31-34]
IGKV2-137*02 (65) P (55) 6 (30.0 cM) CaV24A MAP M80408 [25]
IGKV2-a (49) IGKV2-a*01 F 6 (30.0 cM) + + BALB/c 24A MAP K02417 [9]
IGKV2-f IGKV2-f*01 (65) P (56) 6 (30.0 cM) CaV24D-1 MAP M80411 [25]
IGKV2-f*02 (65) P (57) 6 (30.0 cM) CaV24D-2 MAP M80412 [25]
IGKV2-f*03 (65) P (58) 6 (30.0 cM) CaV24D-3 MAP M80413 [25]
IGKV3 IGKV3-1 IGKV3-1*01 F 6 (30.0 cM) + + BALB/c 21G X16955 [18]
IGKV3-2 IGKV3-2*01 F 6 (30.0 cM) + + BALB/c 21A X16954 [18]
IGKV3-3 IGKV3-3*01 F 6 (30.0 cM) + + BALB/c 18kb K02162 [10]
IGKV3-4 IGKV3-4*01 F 6 (30.0 cM) + + + C57BL/6 21-4 MAP Y15968 [29]
IGKV3-5 IGKV3-5*01 F 6 (30.0 cM) + + + BALB/c 21C K02161 [10]
IGKV3-6 IGKV3-6*01 P (8) 6 (30.0 cM) C57BL/6 21-6 MAP Y15969 [29]
IGKV3-7 IGKV3-7*01 F 6 (30.0 cM) + + + BALB/c 1.6kb K02158 [10]
IGKV3-8 IGKV3-8*01 P (9) 6 (30.0 cM) C57BL/6 21-8 MAP Y15971 [29]
IGKV3-9 IGKV3-9*01 F 6 (30.0 cM) C57BL/6 21-9 MAP Y15972 [29]
IGKV3-10 IGKV3-10*01 F 6 (30.0 cM) + + + BALB/c 21B K02160 [10]
IGKV3-11 IGKV3-11*01 P (10) 6 (30.0 cM) C57BL/6 21-11 MAP Y15973 [29]
IGKV3-12 IGKV3-12*01 F 6 (30.0 cM) + + BALB/c 21E K02159 [10]
IGKV3-12-1 IGKV3-12-1*01 P (67) 6 (30.0 cM) C57BL/6J RP23-66O20 AC153928 [38] C57BL/6J RP23-175B24 AC153855 [38]
IGKV4 IGKV4-50 IGKV4-50*01 F 6 (30.0 cM) C57BL/6 V4-50 MAP AJ235938 [31-34] R13 [11,41]
IGKV4-51 IGKV4-51*01 F 6 (30.0 cM) BALB/c L8 MAP V01565 [7] C3H V4-51 MAP AJ235939 [31-34]
IGKV4-52 (60) IGKV4-52*01 ORF (61) 6 (30.0 cM) C57BL/6 ko4 MAP AJ239198 [31-34]
IGKV4-53 IGKV4-53*01 F 6 (30.0 cM) + + + C57BL/6 kh4 MAP AJ231231 [31-34]
IGKV4-54 (60) IGKV4-54*01 ORF (61) 6 (30.0 cM) C57BL/6 ar4 MAP AJ231223 [31-34]
IGKV4-55 IGKV4-55*01 F 6 (30.0 cM) + + + C57BL/6 at4 MAP AJ231225 [31-34] C57BL/6J RP23-124O23 AC158673 [38]
IGKV4-56 IGKV4-56*01 P (11) 6 (30.0 cM) C57BL/6 ao4 MAP AJ231220 [31-34] C57BL/6J RP23-124O23 AC158673 [38]
IGKV4-57 IGKV4-57*01 F 6 (30.0 cM) + + C57BL/6 ap4 MAP AJ231221 [31-34] C57BL/6J RP23-124O23 AC158673 [38]
IGKV4-57-1 IGKV4-57-1*01 F 6 (30.0 cM) + + C57BL/6J RP23-124O23 AC158673 [38]
IGKV4-58 IGKV4-58*01 F 6 (30.0 cM) + + + BALB/c S107b MAP K00884 [4] R1 [11,41]
C57BL/6 kj4 MAP AJ231233 [31-34]
C57BL/6J RP24-568F14 AC156953 [38]
RP23-124O23 AC158673 [38]
IGKV4-59 IGKV4-59*01 F 6 (30.0 cM) + + C57BL/6 5' part kk4 MAP AJ231234 [31-34] H3 [11,41]
BALB/c VOx1 MAP S37664 [11,41]
C57BL/6J RP24-568F14 AC156953 [38]
RP23-124O23 AC158673 [38]
IGKV4-60 IGKV4-60*01 P (12) 6 (30.0 cM) C57BL/6J RP24-568F14 AC156953 [38] C57BL/6 kl4 MAP AJ235941 [31-34]
C57BL/6J RP23-124O23 AC158673 [38]
IGKV4-61 IGKV4-61*01 F 6 (30.0 cM) + + + C57BL/6 aa4 MAP AJ231209 [31-34] H4 [11,41]
C57BL/6J RP24-568F14 AC156953 [38]
IGKV4-62 IGKV4-62*01 ORF (13) 6 (30.0 cM) C57BL/6 ab4 MAP AJ231210 [31-34] C57BL/6J RP24-568F14 AC156953 [38]
IGKV4-63 IGKV4-63*01 F 6 (30.0 cM) + + + C57BL/6 ac4 MAP AJ231211 [31-34] C57BL/6J RP24-568F14 AC156953 [38]
IGKV4-65 IGKV4-65*01 P (14) 6 (30.0 cM) C57BL/6 ki4 MAP AJ231232 [31-34]
IGKV4-68 IGKV4-68*01 F 6 (30.0 cM) + + C57BL/6 aq4 MAP AJ231222 [31-34] H13 [11,41]
IGKV4-69 IGKV4-69*01 F 6 (30.0 cM) + + + C57BL/6 km4 MAP AJ235942 [31-34] H9 [11,41]
IGKV4-70 IGKV4-70*01 F 6 (30.0 cM) + + + C57BL/6 kn4 MAP AJ235943 [31-34] R9 [11,41]
IGKV4-71 IGKV4-71*01 F 6 (30.0 cM) C57BL/6 al4 MAP AJ231218 [31-34]
IGKV4-72 IGKV4-72*01 F 6 (30.0 cM) + + C57BL/6 am4 MAP AJ231219 [31-34]
IGKV4-73 IGKV4-73*01 F 6 (30.0 cM) C57BL/6 ah4 MAP AJ231216 [31-34]
IGKV4-74 IGKV4-74*01 F 6 (30.0 cM) + + + C57BL/6 ai4 MAP AJ231217 [31-34]
IGKV4-75 IGKV4-75*01 P (15) 6 (30.0 cM) C57BL/6 ka4 MAP AJ231227 [31-34]
IGKV4-77 IGKV4-77*01 P (59) 6 (30.0 cM) C57BL/6 aj4 MAP AJ235940 [31-34] H8 [11,41]
IGKV4-78 IGKV4-78*01 F 6 (30.0 cM) C57BL/6 ad4 MAP AJ231212 [31-34] H1 [11,41]
IGKV4-79 IGKV4-79*01 F 6 (30.0 cM) + + + C57BL/6 ae4 MAP AJ231214 [31-34]
IGKV4-80 IGKV4-80*01 F 6 (30.0 cM) + + + C57BL/6 af4 MAP AJ231213 [31-34]
IGKV4-81 IGKV4-81*01 F 6 (30.0 cM) C57BL/6 ag4 MAP AJ231215 [31-34] R11 [11,41]
IGKV4-83 IGKV4-83*01 P (16) 6 (30.0 cM) C57BL/6 kg4 MAP AJ231230 [31-34] H2 [11,41]
IGKV4-86 IGKV4-86*01 F 6 (30.0 cM) + + BALB/c X24 X05555 [15] H6 [11,41]
C57BL/6 kb4 MAP AJ231228 [31-34]
IGKV4-90 IGKV4-90*01 F 6 (30.0 cM) + + C57BL/6 an4 MAP AJ231224 [31-34] R2 [11,41]
IGKV4-91 IGKV4-91*01 F 6 (30.0 cM) + + C57BL/6 kf4 MAP AJ231229 [31-34]
IGKV4-92 IGKV4-92*01 F 6 (30.0 cM) C57BL/6 ay4 MAP AJ231226 [31-34]
IGKV5 IGKV5-37 IGKV5-37*01 F 6 (30.0 cM) + + C57BL/6 23-37 MAP AJ235963 [31-34]
IGKV5-39 IGKV5-39*01 F (24) 6 (30.0 cM) + + + C57BL/6 23-39 MAP AJ235964 [31-34]
IGKV5-40-1 IGKV5-40-1*01 P 6 (30.0 cM) - - - C57BL/6 fp23r MAP AJ235976 [34]
IGKV5-43 IGKV5-43*01 F 6 (30.0 cM) + + + C3H 23-43 MAP AJ235973 [31-34]
IGKV5-45 IGKV5-45*01 F 6 (30.0 cM) + + + C57BL/6 23-45 MAP AJ235974 [31-34]
IGKV5-48 IGKV5-48*01 F 6 (30.0 cM) + + BALB/c L7 MAP V01564 [5] C57BL/6 23-48 MAP AJ235975 [31-34] (44)
IGKV6 IGKV6-13 IGKV6-13*01 (F) 6 (30.0 cM) + + Vtnp J00569 [8] #g
IGKV6-14 IGKV6-14*01 F 6 (30.0 cM) + + C57BL/6 19-14 MAP Y15975 [29]
IGKV6-15 IGKV6-15*01 F 6 (30.0 cM) + + C57BL/6 19-15 MAP Y15976 [29]
IGKV6-17 IGKV6-17*01 F 6 (30.0 cM) + + + C57BL/6 19-17 MAP Y15978 [29]
IGKV6-20 IGKV6-20*01 F 6 (30.0 cM) + + C57BL/6 19-20 MAP Y15981 [29]
IGKV6-23 IGKV6-23*01 F 6 (30.0 cM) + + + C57BL/6 19-23 MAP AJ235961 [31-34] C57BL/6J RP24-140J8 AC155332 [38]
IGKV6-25 IGKV6-25*01 F 6 (30.0 cM) + + + C57BL/6 19-25 MAP AJ235962 [31-34] C57BL/6J RP24-140J8 AC155332 [38]
IGKV6-29 IGKV6-29*01 F 6 (30.0 cM) C57BL/6 19-29 MAP AJ235967 [31-34] C57BL/6J RP24-140J8 AC155332 [38]
IGKV6-32 IGKV6-32*01 F 6 (30.0 cM) + + + C57BL/6 19-32 MAP AJ235968 [31-34] C57BL/6J RP24-140J8 AC155332 [38]
IGKV6-32*02 (50) F 6 (30.0 cM) BALB/c V-Sera M14360 [13]
IGKV6-b IGKV6-b*01 (51) F 6 (30.0 cM) + + C58 V-Serb M14361 [13]
IGKV6-c IGKV6-c*01 (51) F 6 (30.0 cM) + + SK SK/CamRK M24937 [20]
IGKV6-d IGKV6-d*01 (51) F 6 (30.0 cM) + + PERA PERA/Ei L36249 [20]
IGKV7 IGKV7-33 IGKV7-33*01 F 6 (30.0 cM) + + BALB/c 22G MAP AF044198 [30] C57BL/6 V22-33 MAP AJ235965 [31-34]
IGKV8 IGKV8-16 IGKV8-16*01 F 6 (30.0 cM) + + C57BL/6 V8-16 MAP Y15977 [29]
IGKV8-18 IGKV8-18*01 ORF (20) 6 (30.0 cM) C57BL/6 V8-18 MAP Y15979 [29]
IGKV8-19 IGKV8-19*01 F 6 (30.0 cM) + + C57BL/6 V8-19 MAP Y15980 [29]
IGKV8-21 IGKV8-21*01 F 6 (30.0 cM) + + C57BL/6 V8-21 MAP Y15982 [29]
IGKV8-22 IGKV8-22*01 P (19) 6 (30.0 cM) C57BL/6 V8-22 MAP Y15983 [29]
IGKV8-23-1 IGKV8-23-1*01 ORF (63) 6 (30.0 cM) C57BL/6J RP24-140J8 AC155332 [38]
IGKV8-24 IGKV8-24*01 F 6 (30.0 cM) + + + C57BL/6 V8-24 MAP AJ235944 [31-34] C57BL/6J RP24-140J8 AC155332 [38]
IGKV8-26 IGKV8-26*01 ORF (20) 6 (30.0 cM) C57BL/6 V8-26 MAP AJ235945 [31-34] C57BL/6J RP24-140J8 AC155332 [38]
IGKV8-27 IGKV8-27*01 F 6 (30.0 cM) + + + C57BL/6 V8-27 MAP AJ235946 [31-34] C57BL/6J RP24-140J8 AC155332 [38]
IGKV8-28 IGKV8-28*01 F 6 (30.0 cM) + + + C57BL/6 V8-28 MAP AJ235947 [31-34] C57BL/6J RP24-140J8 AC155332 [38]
IGKV8-28*02 (52) F 6 (30.0 cM) MRL GLvk50 L17135 [24]
IGKV8-30 IGKV8-30*01 F 6 (30.0 cM) + + C3H V8-30 MAP AJ235948 [31-34] C57BL/6J RP24-140J8 AC155332 [38]
IGKV8-31 IGKV8-31*01 P (21) 6 (30.0 cM) C3H V8-31 MAP AJ235957 [31-34]
IGKV8-31*02 P (62) 6 (30.0 cM) C57BL/6J RP24-140J8 AC155332 [38]
IGKV8-34 IGKV8-34*01 F 6 (30.0 cM) 129/Sv V8-34 MAP AJ235958 [31-34]
IGKV9 IGKV9-119 IGKV9-119*01 P (22) 6 (30.0 cM) C57BL/6 bp9 MAP AJ231236 [31-34]
IGKV9-120 IGKV9-120*01 F 6 (30.0 cM) + + C57BL/6 VK41 MAP V00804 [1] AF003293 [26]
C3H bv9 MAP AJ242670 [31-34]
IGKV9-123 IGKV9-123*01 F 6 (30.0 cM) + + + VK9b AF003295 [26] C3H cy9 MAP AJ231250 [31-34]
IGKV9-124 IGKV9-124*01 F 6 (30.0 cM) + + VK9a AF003294 [26] C3H cw9 MAP AJ231248 [31-34]
IGKV9-128 IGKV9-128*01 P (23) 6 (30.0 cM) C3H cl9 MAP AJ231245 [31-34]
IGKV9-129 IGKV9-129*01 ORF (68) 6 (30.0 cM) + + BALB/c M173b K00880 [2] C3H cj9 MAP AJ231244 [31-34]
IGKV10 IGKV10-94 IGKV10-94*01 F 6 (30.0 cM) + + + A/J AJ2 MAP M54906 [23] C3H cp9 MAP AJ231247 [31-34]
LEWES/Ei Vk10B AF441456 [37]
MOR/Rk Vk10B AF441458 [37]
IGKV10-94*02 F 6 (30.0 cM) PERU PERU2 MAP M54908 [23] O20/A Vk10A AF441450 [37]
Vk10A AF441454 [37]
IGKV10-94*03 F 6 (30.0 cM) + AKR AKR2 MAP M54904 [23] MRL MRLB MAP AF346760 [42]
MRL/MpJ Vk10B AF441459 [37]
IGKV10-94*04 F 6 (30.0 cM) CZECHII/Ei Vk10B AF441453 [37]
IGKV10-94*05 F 6 (30.0 cM) O20/A Vk10B AF441460 [37]
IGKV10-94*06 F 6 (30.0 cM) Vk10B AF441455 [37] WSB/Ei Vk10B AF441462 [37]
IGKV10-94*07 (65) F 6 (30.0 cM) CAST/Ei Vk10A AF441452 [37]
IGKV10-94*08 (66) F 6 (30.0 cM) MOLF/Ei Vk10B AF441457 [37]
IGKV10-95 IGKV10-95*01 F (24) 6 (30.0 cM) + + BALB/c VK10c MAP AF029261 [28] C57BL/6 by9 MAP AJ231239 [31-34]
IGKV10-96 IGKV10-96*01 F 6 (30.0 cM) + + + A/J 91A3 M15520 [16] Id(CR) X05795 [17]
A/J AJ1 MAP M54905 [23]
129/Sv ce9 MAP AJ239197 [31-34]
LEWES/Ei Vk10A AF441447 [37]
MOR/Rk Vk10A AF441449 [37]
IGKV10-96*02 F 6 (30.0 cM) + PERU PERU1 MAP M54907 [23] Vk10A AF441446 [37]
IGKV10-96*03 F 6 (30.0 cM) AKR AKR1 MAP M54903 [23] MRL MRLA MAP AF346761 [42]
MOLF/Ei Vk10A AF441448 [37]
IGKV10-96*04 F 6 (30.0 cM) CZECHII/Ei Vk10A AF441444 [37]
IGKV10-96*05 P 6 (30.0 cM) Vk10A AF441445 [37]
IGKV10-96*06 (65) ORF (68) 6 (30.0 cM) CAST/Ei Vk10A AF441443 [37]
IGKV11 IGKV11-106 IGKV11-106*01 P (25) 6 (30.0 cM) C3H ia11 MAP AJ231252 [31-34]
IGKV11-114 IGKV11-114*01 P (26) 6 (30.0 cM) C3H ic11 MAP AJ231253 [31-34]
IGKV11-118 IGKV11-118*01 P (27) 6 (30.0 cM) C3H ie11 MAP AJ231255 [31-34]
IGKV11-125 IGKV11-125*01 F 6 (30.0 cM) + + + 129/Sv if11 MAP AJ231256 [31-34]
IGKV12 IGKV12-38 IGKV12-38*01 F 6 (30.0 cM) + + + C57BL/6 V12-38 MAP AJ235951 [31-34]
IGKV12-40 IGKV12-40*01 P (28) 6 (30.0 cM) C57BL/6 V12-40 MAP AJ235952 [31-34]
IGKV12-41 IGKV12-41*01 F 6 (30.0 cM) + + + C57BL/6 V12-41 MAP AJ235953 [31-34]
IGKV12-41*02 (53) F 6 (30.0 cM) + + BALB/c k2 MAP V00778 [3]
IGKV12-42 IGKV12-42*01 P (29) 6 (30.0 cM) C3H V12-42 MAP AJ235954 [31-34]
IGKV12-44 IGKV12-44*01 F 6 (30.0 cM) + + C3H V12-44 MAP AJ235955 [31-34]
IGKV12-46 IGKV12-46*01 F 6 (30.0 cM) + + C57BL/6 V12-46 MAP AJ235956 [31-34]
IGKV12-47 IGKV12-47*01 P (30) 6 (30.0 cM) C57BL/6 V12-47 MAP AJ235959 [31-34]
IGKV12-49 IGKV12-49*01 P (31) 6 (30.0 cM) C57BL/6 V12-49 MAP AJ235960 [31-34]
IGKV12-66 IGKV12-66*01 P (32) 6 (30.0 cM) C57BL/6 fr12 MAP AJ235934 [31-34]
IGKV12-67 IGKV12-67*01 P (33) 6 (30.0 cM) C57BL/6 fg12 MAP AJ235933 [31-34]
IGKV12-89 IGKV12-89*01 F 6 (30.0 cM) + + + C57BL/6 fl12 MAP AJ235950 [31-34]
IGKV12-98 IGKV12-98*01 F 6 (30.0 cM) + + + C3H ci12 MAP AJ235949 [31-34]
IGKV12-e IGKV12-e*01 F 6 (30.0 cM) BALB/c k3 MAP J00546 [43]
IGKV13 IGKV13-54-1 IGKV13-54-1*01 P 6 (30.0 cM) - - - C57BL/6 gy33r MAP AJ132680 [34]
IGKV13-55-1 IGKV13-55-1*01 P 6 (30.0 cM) - - - C57BL/6 gx33r MAP AJ132679 [34] C57BL/6J RP23-124O23 AC158673 [38]
IGKV13-56-1 IGKV13-56-1*01 P 6 (30.0 cM) - - - C57BL/6 gg33r MAP AJ132675 [34] C57BL/6J RP23-124O23 AC158673 [38]
IGKV13-57-1 IGKV13-57-1*01 P 6 (30.0 cM) - - - C57BL/6 gz33r MAP AJ132681 [34] C57BL/6J RP23-124O23 AC158673 [38]
IGKV13-57-2 IGKV13-57-2*01 P (70) 6 (30.0 cM) - - - C57BL/6J RP23-124O23 AC158673 [38] C57BL/6J RP24-568F14 AC156953 [38]
IGKV13-61-1 IGKV13-61-1*01 P 6 (30.0 cM) - - - C57BL/6 gh33r MAP AJ132676 [34] C57BL/6J RP24-568F14 AC156953 [38]
IGKV13-62-1 IGKV13-62-1*01 P 6 (30.0 cM) - - - C57BL/6 gc33r MAP AJ132672 [34]
IGKV13-62-1*02 P 6 (30.0 cM) - - - C57BL/6J RP24-568F14 AC156953 [38]
IGKV13-64 IGKV13-64*01 P (34) 6 (30.0 cM) C57BL/6 gu33 MAP AJ235969 [31-34]
IGKV13-64*02 P (62) 6 (30.0 cM) - - - C57BL/6J RP24-568F14 AC156953 [38]
IGKV13-71-1 IGKV13-71-1*01 P 6 (30.0 cM) - - - C57BL/6 gd33r MAP AJ132673 [34]
IGKV13-73-1 IGKV13-73-1*01 P 6 (30.0 cM) - - - C57BL/6 go33r MAP AJ132677 [34]
IGKV13-74-1 IGKV13-74-1*01 P 6 (30.0 cM) - - - C57BL/6 gv33r MAP AJ132678 [34]
IGKV13-76 IGKV13-76*01 P (35) 6 (30.0 cM) C57BL/6 ga33 MAP AJ231271 [31-34]
IGKV13-78-1 IGKV13-78-1*01 P 6 (30.0 cM) - - - C57BL/6 gb33r MAP AJ132671 [34]
IGKV13-80-1 IGKV13-80-1*01 P 6 (30.0 cM) - - - C57BL/6 ge33r MAP AJ132674 [34]
IGKV13-82 IGKV13-82*01 P (36) 6 (30.0 cM) C57BL/6 gq33 MAP AJ231276 [31-34]
IGKV13-84 IGKV13-84*01 F 6 (30.0 cM) + + C57BL/6 gm33 MAP AJ231273 [31-34] BALB/c Vk34C M35156 [21] (45)
IGKV13-85 IGKV13-85*01 F 6 (30.0 cM) + + C57BL/6 gn33 MAP AJ231274 [31-34]
IGKV13-85*02 (54) F 6 (30.0 cM) BALB/c Vk34B M35154 [21] (45)
IGKV13-85*03 (54) F 6 (30.0 cM) AKR Vk34A M35155 [21] (45)
IGKV13-87 IGKV13-87*01 P (37) 6 (30.0 cM) C57BL/6 gp33 MAP AJ231275 [31-34]
IGKV13-89-1 IGKV13-89-1*01 P 6 (30.0 cM) - - - C57BL/6 gf33r MAP AJ231272 [34]
IGKV14 IGKV14-100 IGKV14-100*01 F 6 (30.0 cM) + + C3H cf9 MAP AJ231243 [31-34]
IGKV14-111 IGKV14-111*01 F 6 (30.0 cM) + + BALB/c L6 MAP V01563 [5] VT1 V01522 [35]
9M M74713 [22]
C57BL/6 ba9 MAP AJ231235 [31-34]
IGKV14-118-1 IGKV14-118-1*01 P 6 (30.0 cM) - - - C57BL/6 bz9 MAP AJ277844 [44]
IGKV14-118-2 IGKV14-118-2*01 P 6 (30.0 cM) - - - C57BL/6 bq9 MAP AJ231237 [34]
IGKV14-126 IGKV14-126*01 F (69) 6 (30.0 cM) C57BL/6 IgK9-128 MAP AY591690 [40]
IGKV14-126*02 P (38) 6 (30.0 cM) C3H br9 MAP AJ231238 [31-34]
IGKV14-126-1 IGKV14-126-1*01 P 6 (30.0 cM) - - - C57BL/6 co9 MAP AJ231246 [34]
IGKV14-130 IGKV14-130*01 F 6 (30.0 cM) + + + C57BL/6 cb9 MAP AJ231241 [31-34]
IGKV14-134-1 IGKV14-134-1*01 P 6 (30.0 cM) - - - C3H cx9 MAP AJ231249 [34] 129/Sv 294A9 Z72385 [27]
IGKV15 IGKV15-97 IGKV15-97*01 P (39) 6 (30.0 cM) C3H gk32 MAP AJ231267 [31-34]
IGKV15-101 IGKV15-101*01 P (40) 6 (30.0 cM) C3H gl32 MAP AJ231268 [31-34]
IGKV15-101-1 IGKV15-101-1*01 P 6 (30.0 cM) - - - C3H gt32r MAP AJ231251 [34]
IGKV15-102 IGKV15-102*01 P (41) 6 (30.0 cM) C3H gs32 MAP AJ231270 [31-34]
IGKV15-103 IGKV15-103*01 ORF (42) 6 (30.0 cM) + + C3H gr32 MAP AJ231269 [31-34]
IGKV16 IGKV16-104 IGKV16-104*01 F 6 (30.0 cM) + + C3H RF MAP AJ235936 [31-34]
IGKV17 IGKV17-121 IGKV17-121*01 F 6 (30.0 cM) + + C57BL/6 bt20 MAP AJ231258 [31-34]
IGKV17-127 IGKV17-127*01 F 6 (30.0 cM) + + C57BL/6 bw20 MAP AJ231259 [31-34]
IGKV17-134 IGKV17-134*01 P (43) 6 (30.0 cM) 129/Sv 294A9 MAP Z72386 [27] C57BL/6 bk20 MAP AJ231257 [31-34]
IGKV18 IGKV18-36 IGKV18-36*01 F 6 (30.0 cM) C3H dv-36 MAP AJ235966 [31-34]
IGKV19 IGKV19-93 IGKV19-93*01 F 6 (30.0 cM) + + C57BL/6 gj38c MAP AJ235935 [31-34]
IGKV19-93*02 F (64) 6 (30.0 cM) S65298 [39]
IGKV20 IGKV20-101-2 IGKV20-101-2*01 F 6 (30.0 cM) + C57BL/6J RP23-29F15 AC122918 [45] C57BL/6J RP24-418F6 AC174597 [46]

#g: rearranged genomic DNA.
MAP: mapped sequences.

The nomenclature rules from the International Committee for Standardized Nomenclature for Mice state the following: "Most laboratory mice have contributions from both Mus musculus musculus and Mus musculus domesticus. There is evidence that smaller contributions may also have come from Mus musculus molossinus and Mus musculus castaneus. Therefore, they should not be referred to by species name, but rather as "laboratory mice" or by use of a specific strain or stock name. In addition, some recently developed laboratory mouse strains are derived wholly from other Mus species or subspecies, such as Mus spretus." Information communicated by Janan Eppig (28/03/2002).

IMGT notes:
  1. (1) A lot of mutations, DELETIONs in the L-PART2 and in the FR1-IMGT and an INSERTION of 1 nucleotide (t at position 1101) in the FR2-IMGT.
  2. (2) In frame STOP-CODON at codon 10 in L-PART1.
  3. (3) A lot of mutations, DELETIONs and INSERTIONs in the V-REGION.
  4. (4) INSERTION of 1 nucleotide (a at position 672) in the CDR1-IMGT and INSERTION of 1 nucleotide (a at position 833) in the FR3-IMGT.
  5. (5) A lot of mutations, DELETIONs and INSERTIONs in the V-REGION and non canonical V-HEPTAMER: CGCAGTG instead of CACAGTG.
  6. (6) INSERTION of 1 nucleotide (a at position 852) in the FR3-IMGT.
  7. (7) DELETION of 1 nucleotide (between positions 720/721) in FR1-IMGT and DELETION of 22 nucleotides (between positions 781/782) between the FR1-IMGT and the CDR1-IMGT.
  8. (8) INSERTION of 566 nucleotides (positions 706-1271) in CDR3-IMGT.
  9. (9) In frame STOP-CODON (positions 332-334) at codon 17 in FR1-IMGT.
  10. (10) INSERTION of 566 nucleotides (positions 713-1278) in CDR3-IMGT.
  11. (11) DELETION of 3 nucleotides (between positions 178/179) in the L-PART1.
  12. (12) No INIT-CODON.
  13. (13) Non canonical V-NONAMER: ACCCTCTAA instead of ACAAAAACC.
  14. (14) STOP-CODON in the FR2-IMGT, DELETION of 1 nucleotide (between positions 594/595), and non canonical OCTAMER, V-HEPTAMER and V-NONAMER.
  15. (15) INSERTION of 1 nucleotide (position 162) in the L-PART1 and STOP-CODONs in the FR2-IMGT.
  16. (16) No INIT-CODON, in frame STOP-CODON (position 686-688) at codon 53 in the FR2-IMGT and non canonical OCTAMER.
  17. (17) Non canonical V-HEPTAMER: CACAGAC instead of CACAGTG and DELETION in the V-SPACER (only 4 nucleotides instead 12 nucleotides).
  18. (18) Non canonical V-NONAMER: AAAAAAAAA instead of ACAAAAATA.
  19. (19) STOP-CODON (positions 561-563) in FR2-IMGT, INSERTION of 1 nucleotide (g at position 600) and INSERTION of 4 nucleotides (positions 606-609) in FR3-IMGT, and DELETION of 3 nucleotides (between positions 715/716) in CDR3-IMGT.
  20. (20) Non canonical V-HEPTAMER: CACAGAG instead of CACAGTG.
  21. (21) INSERTION of 5 nucleotides (positions 698-702) in FR3-IMGT and non canonical OCTAMER: ATTCTCAC instead of NTTTGCAT.
  22. (22) In frame STOP-CODON (571-573) instead of the conserved 1st-CYS in the FR1-IMGT.
  23. (23) In frame STOP-CODON (positions 490-492) at codon 74 in the FR3-IMGT.
  24. (24) Non canonical V-HEPTAMER: CACAATG instead of CACAGTG.
  25. (25) Non canonical DONOR-SPLICE: NGG instead of NGT in the L-PART1 and DELETION of 2 nucleotides (between positions 360/361) in the CDR1-IMGT.
  26. (26) DELETION of 2 nucleotides (between positions 338/339) in the FR1-IMGT and DELETION of 1 nucleotide (between positions 408/409), and non canonical V-HEPTAMER: CACAATG instead of CACAGTG.
  27. (27) INSERTION of 4 nucleotides (positions 455-458) and DELETION of 1 nucleotide (between positions 462/463) in the FR1-IMGT, and non canonical V-HEPTAMER: CAGAGTG instead of CACAGTG, non canonical V-NONAMER: ACATAAGCC.
  28. (28) In frame STOP-CODON (positions 451-453) at codon 43 in the FR2-IMGT.
  29. (29) DELETION of 16 nucleotides (between positions 467/468) in the FR3-IMGT, non canonical V-HEPTAMER: CAAGTG instead of CACAGTG and non canonical V-NONAMER: ATATAAGCA instead of ACATAAACC.
  30. (30) DELETION in the CDR3-IMGT and non canonical V-HEPTAMER: CAAGTG instead of CACAGTG.
  31. (31) DELETION of 1 nucleotide in L-PART1, INSERTION of 1 nucleotide (position 474), DELETION of 1 nucleotide (between positions 495/496) and mutations in the FR3-IMGT.
  32. (32) INSERTION of 1 nucleotide (t at position 322) in the FR1-IMGT.
  33. (33) INSERTION of 1 nucleotide (c at position 434) in the FR1-IMGT.
  34. (34) DELETION of 1 nucleotide (between positions 334/335) in the FR1-IMGT, DELETION of 1 nucleotide (between positions 416/417) and non canonical V-HEPTAMER: CACAATG instead of CACAGTG.
  35. (35) In frame STOP-CODON at codon 6 in the FR1-IMGT and in frame STOP-CODON at codon 39 in the FR2-IMGT.
  36. (36) STOP-CODONs in the L-PART1 and STOP-CODONs in the FR1-IMGT and in the FR2-IMGT and non canonical V-HEPTAMER: CACAATG instead of CACAGTG.
  37. (37) STOP-CODONs in the L-PART1 and STOP-CODON in the FR2-IMGT, DELETION of 1 nucleotide (between positions 526/527) in the FR3-IMGT, and non canonical OCTAMER and V-HEPTAMER.
  38. (38) INSERTION of 1 nucleotide (position 418) in the FR1-IMGT and non canonical V-HEPTAMER: CACGTTG instead of CACAGTG
  39. (39) DELETION of 12 nucleotides (between positions 459/460) in the FR3-IMGT and non canonical V-HEPTAMER: CACATGT instead of CACAGTG.
  40. (40) STOP-CODONs in the FR1-IMGT and the FR3-IMGT and non canonical V-HEPTAMER: TACAGTG instead of CACAGTG.
  41. (41) A lot of INSERTIONs in the L-PART1, in frame STOP-CODONs at codons 3 and 18 in the FR1-IMGT and in frame STOP-CODON at codon 44 in the FR2-IMGT, and non canonical OCTAMER
  42. (42) Non canonical DONOR_SPLICE: NGC instead of NGT.
  43. (43) DELETION of 4 nucleotides (between positions 497/498) in the FR1-IMGT.
  44. (44) Partial V-REGION: only AA66 to 71 are present (partial FR3-IMGT).
  45. (45) Partial V-REGION: AA102 to 104 are missing (partial FR3-IMGT).
  46. (46) Sequences differing by 8 nucleotides or less than 8 nucleotides from germline mapped reference sequences are temporatily considered as alleles of these sequences. Sequences differing by more than 8 nucleotides from germline mapped reference sequences are considered as new unmapped genes and are designated by a number for the subgroup, followed by a hyphen and small letter, for example IGKV2-a. These data need to be confirmed by genetic data.
  47. (47) This sequence, which differs from the germline mapped reference sequence by 5 nucleotides, can be considered as temporarily an allele.
  48. (48) This sequence, which differs from the germline mapped reference sequence by 2 nucleotides, can be considered as temporarily an allele.
  49. (49) This sequence, which differs from the nearest mapped germline gene (AJ132683) by 21 nucleotides, can be considered as a new unmapped gene.
  50. (50) This sequence, which differs from the germline mapped reference sequence by 1 nucleotide, can be considered as temporarily an allele.
  51. (51) These sequences, which differ from the nearest mapped germline gene (AJ235968) by respectively 11, 9 and 15 nucleotides, can be considered as new unmapped genes.
  52. (52) This sequence, which differs from the germline mapped reference sequence by 8 nucleotides, can be considered as temporarily an allele.
  53. (53) This sequence, which differs from the germline mapped reference sequence by 1 nucleotide, can be considered as temporarily an allele.
  54. (54) These sequences, which differ from the germline mapped reference sequence by respectively 3 and 7 nucleotides, can be considered as temporarily alleles.
  55. (55) DELETION of 5 nucleotides (between positions 7 and 8) in the FR1-IMGT leading to a frameshift and mutations in the V-REGION and INSERTION of 3 nucleotides between positions 288 and 289.
  56. (56) INSERTION of 1 nucleotide (position 879) in FR3-IMGT leading to a frameshift.
  57. (57) INSERTION of 1 nucleotide (position 828) in FR3-IMGT leading to a frameshift.
  58. (58) STOP-CODONs in FR2-IMGT and INSERTION of 1 nucleotide (position 780) in FR3-IMGT.
  59. (59) In frame STOP-CODON (positions 540-542) at codon 40 in FR2-IMGT .
  60. (60) The IGKV4-52*01 (AJ239198) and the IGKV4-54*01 (AJ231223) V-REGION nucleotide sequences are 100% identical. These two genes differ by one nucleotide in their L-PART2 (at position 12 according to the IMGT numbering).IGKV 4-52 is not found in BAC clone AC153615.It is not yet known if IGHV4-52 represente an allele of IGKV4-54 or polymorphic gene by insertion/deletion.
  61. (61) ORF because no conserved CONSERVED-TRP.
  62. (62) Frameshifts in V-REGION.
  63. (63) Deletion of 7 amino acids in FR1-IMGT.
  64. (64) Deletion of one nucleotide (g) at position 133 in L-PART1, probably resulting from a sequencing error.
  65. (65) Southeastern Asian house mouse (Mus musculus castaneus) species.
  66. (66) Japanese wild mouse (Mus musculus molossinus) species.
  67. (67) deletion of 9 nucleotides in FR2-IMGT, corresponding to the codons 49, 50 and 51 according to the IMGT unique numbering for V-DOMAIN, stop codon at codon 67 in FR3-IMGT, stop codon at codon 67 in FR3-IMGT, No DONOR-SPLICE at the end of L-PART-1, frameshift in FR3-IMGT
  68. (68) ORF because no conserved CONSERVED_TRP.
  69. (69) Despite its non-canonical V-HEPTAMER, IGKV14-126*01 is functional in C57BL/6J (and also in BALB/c, NOD) as found rearranged in cDNA with defined specificity
  70. (70) In frame STOP-CODONs in V-REGION at positions AA 41, 44, 69 and 92, in frame STOP-CODON in L-PART1
IMGT references:
  1. [1] Seidman J.G. et al., Nature, 280, 370-375 (1979). PMID:111146
  2. [2] Max E.E. et al., Cell, 21, 793-799 (1980). PMID:6777049
  3. [3] Nishioka Y. et al., J. Biol. Chem., 255, 3691-3694 (1980). PMID:6767723
  4. [4] Kwan S.P et al., Cell, 26, 57-66 (1981). PMID:6799208
  5. [5] Pech M. et al., Nature, 291, 668-670 (1981). PMID:6264318
  6. [6] Selsing E. et al., Cell, 25, 47-58 (1981). PMID:6791832
  7. [7] Höchtl J. et al., Proc. Natl. Acad. Sci. U.S.A., 79, 1383-1387 (1982). PMID:6803241
  8. [8] Hawley R.G. et al., Proc. Natl. Acad. Sci. U.S.A., 79, 7425-7429 (1982). PMID:6296832
  9. [9] Joho R. et al., EMBO J., 3, 185-191 (1984). PMID:6546718
  10. [10] Heinrich G. et al., J. Exp. Med., 159, 417-435 (1984). PMID:6420501
  11. [11] Even J. et al., EMBO J., 4, 3439-3445 (1985). PMID:3937727
  12. [12] Kelley D.E. et al., Mol. Cell. Biol., 5, 1660-1675 (1985). PMID:3927151
  13. [13] Boyd R. T. et al., Proc. Natl. Acad. Sci. U.S.A., 83, 9134-9138 (1986). PMID:3097643
  14. [14] Corbet S. et al., J. Immunol., 138, 932-939 (1987). PMID:3100621
  15. [15] Heller M. et al., J. Exp. Med., 166, 637-646 (1987). PMID:3040883
  16. [16] Sanz I. et al., Proc. Natl. Acad. Sci. U.S.A., 84, 1085-1089 (1987). PMID:3103124
  17. [17] Wysocki L.J. et al., J. Exp. Med., 166, 1-11 (1987). PMID:3036994
  18. [18] Alanen A. et al., Eur. J. Immunol., 19, 1961-1963 (1989). PMID:2583230
  19. [19] Ng K.H. et al., J. Immunol., 143, 638-648 (1989). PMID:2567773
  20. [20] Ponath P.D. et al., Immunogenetics, 29, 249-257 (1989). PMID:2495249
  21. [21] Valiante N.M. and Caton A.J., Immunogenetics, 32, 345-350 (1990). PMID:2123475
  22. [22] Yang J.N. et al., J. Virol., 65, 3911-3914 (1991). PMID:1645798
  23. [23] Kim S.O. et al., Immunogenetics, 34, 231-241 (1991). PMID:1916951
  24. [24] Foster M.H. et al., J. Immunol., 151, 814-824 (1993). PMID:8335911
  25. [25] Henderson T.J. et al., Immunogenetics, 37, 426-436 (1993). PMID:8436417
  26. [26] Ulrich H. D. et al., Immunogenetics, 47, 91-95 (1997). PMID:9382926
  27. [27] Schupp I.W. et al., Immunogenetics, 45, 180-187 (1997). PMID:8995184
  28. [28] Fitzsimmons S.P. et al., J. Immunol., 161, 2290-2300 (1998). PMID:9725223
  29. [29] Kirschbaum T. et al., Eur. J. Immunol., 28, 1458-1466 (1998). PMID:9603450
  30. [30] Whitcomb E.A. et al., J. Immunol., 160, 4904-4913 (1998). PMID:9590238
  31. [31] Kirschbaum T. et al., Eur. J. Immunol., 29, 2057-2064 (1999). PMID:10427967
  32. [32] Röschenthaler F. et al., Eur. J. Immunol., 29, 2065-2071 (1999). PMID:10427968
  33. [33] Thiebe R. et al., Eur. J. Immunol., 29, 2072-2081 (1999). PMID:10427969
  34. [34] Schäble K.F. et al., Eur. J. Immunol., 29, 2082-2086 (1999). PMID:10427970
  35. [35] Gorski J. et al., Science, 220, 1179-1181 (1983). PMID:6857243
  36. [36] Larijani M. et al., Nucleic Acids Res., 27, 2304-2309 (1999). PMID:10325418
  37. [37] Fitzsimmons S.P. et al., Immunogenetics, 54, 9-19 (2001). PMID:11976787
  38. [38] Worley K.C., Unpublished (2005).
  39. [39] Deev S.M. et al., Mol. Biol., 27, 924-933 (1993). PMID:8361498
  40. [40] Brekke K.M. et al., Immunogenetics, 56, 490-505 (2004). PMID:15378297
  41. [41] Milstein, C. et al., Eur. J. Immunol., 22, 1627-1634 (1992). PMID:1601044
  42. [42] Fitzsimmons S.P. et al., Unpublished (2001).
  43. [43] Seidman J.G. et al., Proc. Natl. Acad. Sci. U.S.A., 75, 3881-3885 (1978). PMID:279004
  44. [44] Röschenthaler F. et al., Eur. J. Immunol., 30, 3349-3354 (2000). PMID:11093151
  45. [45] Wilson R.K., Unpublished.
  46. [46] Henke J., Unpublished.

Chromosomal orphon set IGKV

IMGT subgroup IMGT gene name IMGT allele name Fct Chromosomal localization R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGKV1 IGKV1/OR6-1 IGKV1/OR6-1*01 P (1) 6 C57BL/6 gw1 MAP AJ235937 [3] BALB/c Psi 1.7 X58991 [1]
IGKV1/OR16-1 IGKV1/OR16-1*01 P (2) 16 129/Sv 68 MAP Z72381 [2] C57BL/6 be2 MAP AJ235971 [3]
IGKV1/OR19-1 IGKV1/OR19-1*01 P (3) 19 129/Sv 70/2 MAP Z72383 [2] C57BL/6 bn2 MAP AJ235972 [3]
IGKV14 IGKV14/OR6-2 IGKV14/OR6-2*01 P (4) 6 C57BL/6 ca9 MAP AJ231240 [3] BALB/c 9B.8 X58992 [1]
IGKV14/OR6-3 IGKV14/OR6-3*01 P (5) 6 C57BL/6 cc9 MAP AJ231242 [3]
IGKV14/OR16-2 IGKV14/OR16-2*01 P (6) 16 C57BL/6 bg9 MAP AJ235977 [3]
IGKV17 IGKV17/OR16-3 IGKV17/OR16-3*01 ORF (7) 16 C57BL/6 bf20part1 (L-PART1) MAP AJ235930 [3]
bf20part2 (V-EXON) MAP AJ235929 [3]
IGKV17/OR19-2 IGKV17/OR19-2*01 ORF (8) 19 C57BL/6 bu20part1 (L-PART1) MAP AJ235931 [3]
bu20part2 (V-EXON) MAP AJ235932 [3]

MAP: mapped sequences.

IMGT notes:
  1. (1) A lot of mutations, DELETIONs and INSERTIONs.
  2. (2) INSERTION of 1 nucleotide (position 645) in CDR1-IMGT and DELETION of 1 nucleotide (between positions 796/797) in FR3-IMGT.
  3. (3) DELETION of 2 nucleotides (between positions 518/519) in FR1-IMGT and DELETION of 1 nucleotide (between positions 742/743) in FR3-IMGT.
  4. (4) INSERTION of 2 nucleotides (positions 560-561) in FR3-IMGT.
  5. (5) INSERTION of 1 nucleotide (positions 385) in CDR1-IMGT and DELETION of 3 nucleotides (between positions 427/428) in FR2-IMGT.
  6. (6) DELETION or INSERTION leading a frameshift in the CDR3-IMGT.
  7. (7) CONSERVED-TRP (codon 41 in FR2-IMGT) is replaced by a Tyr.
  8. (8) CONSERVED-TRP (codon 41 in FR2-IMGT) is replaced by a Gly and 2nd-CYS (codon 104 in FR3-IMGT) is replaced by a Tyr.
IMGT references:
  1. [1] Lawler A.M. et al., Mol. Immunol. 29, 295-301 (1992). PMID:1557040
  2. [2] Schupp I. W. et al., Immunogenetics, 45, 180-187 (1997). PMID:8995184
  3. [3] Schäble K.F. et al., Eur. J. Immunol., 29, 2082-2086 (1999). PMID:10427970
Created:
30/07/1998
Last updated:
15/05/2017
Authors:
Christèle Martinez Jean, Delphine Guiraudou, Joumana Jabado-Michaloud, Fatena Bellahcene