IMGT Repertoire (MH)

IMGT Collier de Perles for Homo sapiens HLA-DRB1 [D2] (C-LIKE-DOMAIN)

HLA-DRB1 (NM_002124)

This figures have been generated with the IMGT/Collier de Perles tool for C-DOMAIN developed by Quentin Kaas (11/03/2002).

Legend:

Amino acids are shown in the one-letter abbreviation.
Hydrophobic amino acids (hydropathy index with positive value) and Tryptophan (W) found at a given position in more than 50 % of analysed Ig and TcR sequences are shown in blue.
All Proline (P) are shown in yellow.
Arrows indicate the direction of the beta sheets and their different designations in 3D structure. This information has to be used carefully if not supported by experimental data.
Hachured circles or squares correspond to missing positions according to the IMGT unique numbering.
Grey circles or squares correspond to missing positions according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
Missing positions in IMGT Colliers de Perles based on 3D structures may be due to incomplete experimental data.
The positions 26, 39 and 104 are shown in squares by homology with the corresponding positions in the V-REGIONs. Positions 45 and 77 which delimit the characteristic "CD" strand of the C-DOMAINs, and position 118 which corresponds structurally to J-PHE or J-TRP of the J-REGION, are also shown in squares.

See also:

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