IMGT Repertoire (RPI)
Alignment of alleles: Human IGLL2
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Accession Allele EXON 1
number name
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1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
M C H S G S C W D L L G P A L P S A P T
X52203 , IGLL2*01 (cDNA)(EX1) ATG TGT CAC TCA GGG AGT TGC TGG GAC CTA CTG GGC CCA GCG TTG CCA TCA GCA CCA ACA
AP000347, IGLL2*02 (2) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
A S E R G T Y A G V T P R L W A A P A S
X52203 , IGLL2*01 (cDNA)(EX1) GCT TCA GAG AGG GGG ACA TAT GCT GGG GTG ACT CCA AGG CTG TGG GCG GCA CCT GCC TCA
AP000347, IGLL2*02 (2) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
D R E Q A Q R H Y W G T L L G Y W P P P
X52203 , IGLL2*01 (cDNA)(EX1) GAC AGG GAA CAG GCA CAG AGA CAC TAC TGG GGG ACA CTA CTG GGA TAC TGG CCA CCC CCC
AP000347, IGLL2*02 (2) --T --A --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79
C P V P G S Q P T H C S P V P L T P S
X52203 , IGLL2*01 (cDNA)(EX1) TGC CCT GTG CCT GGG TCA CAG CCT ACA CAC TGC AGC CCT GTG CCC CTC ACA CCC AGC AG
AP000347, IGLL2*02 (2) (3) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --
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Accession Allele EXON 2
number name
___________________________________________________________________________________________________________________________________ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
R F L L Q R G S W T G A R C W P W G F Q S
X52203 , IGLL2*01 (cDNA)(EX2) G TTC CTG CTC CAG CGT GGC TCC TGG ACT GGC GCC AGA TGC TGG CCC TGG GGG TTT CAA TCC
AP000347, IGLL2*02 (2) - --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38
K H N S V K H V F G S G T Q L T V L
X52203 , IGLL2*01 (cDNA)(EX2) AAG CAT AAT TCA GTG AAG CAT GTG TTT GGC AGT GGG ACC CAG CTC ACT GTT TTA G
AP000347, IGLL2*02 (2) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
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Accession Allele EXON 3
number name
___________________________________________________________________________________________________________________________________ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
G Q P K T T P S V I L F L P S C
X52203 , IGLL2*01 (cDNA)(EX3)(1) GT CAG CCC AAG ACT ACC CCG TCG GTC ATT CTG TTC CTG CCG TCC TGT
X52204 , IGLL2*01 (cDNA) -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
L02326 , IGLL2*01 -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
AP000347, IGLL2*02 (2) -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
_____AB_____
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
E E P Q A N K A T L V <C L M N N
X52203 , IGLL2*01 (cDNA)(EX3)(1) GAG GAG CCC CAA ... ... ... GCC AAC AAG GCC ACA CTG GTG TGT CTC ATG AAT AAC TT.
X52204 , IGLL2*01 (cDNA) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --.
L02326 , IGLL2*01 --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --.
AP000347, IGLL2*02 (2) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --.
_______________BC_______________ _________CD_________
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
Y P G I L M V T W K A D G T L I T Q
X52203 , IGLL2*01 (cDNA)(EX3)(1) TAT CCG ... ... GGA ATC TTG ATG GTG ACC TGG AAG GCA GAT GGT ACC CTC ATC ACC CAG
X52204 , IGLL2*01 (cDNA) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
L02326 , IGLL2*01 --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
AP000347, IGLL2*02 (2) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
________ ___________________DE___________________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
S V E K T T P S K Q S N
X52203 , IGLL2*01 (cDNA)(EX3)(1) ... ... AGC GTG GAG AAG ACC ACG CCC TCC AAA CAG AGC AAC ... ... ... ... ... ...
X52204 , IGLL2*01 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ...
L02326 , IGLL2*01 ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ...
AP000347, IGLL2*02 (2) ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ...
________________ ___EF___
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
N K Y V A S S Y L S L T P E Q W R S
X52203 , IGLL2*01 (cDNA)(EX3)(1) AAC AAG TAC GTG GCC AGC AGC TAC CTG AGC CTG ACG CCC GAG CAG TGG ... ... AGG TCC
X52204 , IGLL2*01 (cDNA) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- ---
L02326 , IGLL2*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- ---
AP000347, IGLL2*02 (2) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- ---
_________________________FG_________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
R R S Y S <C Q V M Q E G S T V E
X52203 , IGLL2*01 (cDNA)(EX3)(1) CGC AGA AGC TAC AGC TGC CAG GTT ATG CAA GAA ... ... ... ... GGG AGC ACC GTG GAG
X52204 , IGLL2*01 (cDNA) --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- ---
L02326 , IGLL2*01 --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- ---
AP000347, IGLL2*02 (2) --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- ---
119 120 121 122 123 124 125 126 127 128
K S V A P A E C S *
X52203 , IGLL2*01 (cDNA)(EX3)(1) AAG TCA GTG GCC CCT GCA GAA TGT TCA
X52204 , IGLL2*01 (cDNA) --- --- --- --- --- --- --- --- ---
L02326 , IGLL2*01 --- --- --- --- --- --- --- --- ---
AP000347, IGLL2*02 (2) --- --- --- --- --- --- --- --- ---
Legend:
- When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters.
- Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest sequence.
- Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
- Exon names are shown between parentheses on the first line.
- Cysteine involved in the disulfide bridge are shown in purple.
- STOP-CODON is indicated by an asterisk.
| (1) | IGLL2 is a Pseudogene, because of one nucleotide DELETION in EX3 (codon at positon 28 according to the IMGT numbering for C-DOMAIN and C-LIKE-DOMAIN) leading to a frameshift. |
| (2) | The sequence from AP000347 (IGLL2*02) is in complementary inverted orientation in the flat file. |
| (3) | The splicing type between EX1 and EX2 is codon_start 2, instead of the usual splicing type (codon_start 3) for IG and TR. |
See also:
- IMGT Repertoire:
- IMGT Scientific chart:
- IMGT Index:
- IMGT Education (FR):
- Tools:
Created: 28/02/2003
Last updated: Friday, 22-Sep-2023 18:32:05 CEST
Author: Dominique Scaviner
Editor: Elodie Gemrot
Last updated: Friday, 22-Sep-2023 18:32:05 CEST
Author: Dominique Scaviner
Editor: Elodie Gemrot
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