IMGT/GENE-DB

Major updates since November 2015

07 March 2023 - Creation of the Gorilla gorilla gorilla (western lowland gorilla) IGL reference directory :
- Addition of 86 genes and 119 IGLV alleles (34 F, 15 ORF, 70 P): IGLV(I)-70-1*01 P, IGLV(I)-70*01 P, IGLV4-69*01 P, IGLV4-69*02 P, IGLV(VII)-68-1*01 P, IGLV(I)-68*01 P, IGLV1-67-1-*01 P, IGLV10-67*01 P, IGLV1-62*01 P, IGLV(IV)-61-1*01 P, IGLV(V)-61-1*01 P, IGLV8-61*01 F, IGLV8-61*02 F, IGLV(III)-60-1*01 P, IGLV(III)-60-1*02 P, IGLV4-60*01 F, IGLV(VII)-59-1*01 P, IGLV(III)-59-1*01 P, IGLV(III)-59-1*02 P, IGLV(IV)-59*01 P, IGLV(V)-58*01 P, IGLV(V)-58*02 P, IGLV6-57*01 F, IGLV(I)-56*01 P, IGLV(IV)-55-1*01 P, IGLV11-55*01 ORF, IGLV11-55*02 ORF, IGLV10-54*01 ORF, IGLV(IV)-53*01 P, IGLV(IV)-53-2*02 P, IGLV5-52*01 ORF, IGLV5-52*02 P, IGLV1-51*01 F, IGLV1-51*02 F, IGLV1-50*01 ORF, IGLV1-50*02 ORF, IGLV9-49*01 F, IGLV(I)-48-1*01 P, IGLV5-48*01 F, IGLV5-48*02 P, IGLV1-47*01 F, IGLV1-47*02 P, IGLV7-46*01 F, IGLV(I)-45-1*01 P, IGLV(I)-45-1*02 P, IGLV5-45*01 F, IGLV1-44*01 F, IGLV1-44*02 F, IGLV7-43*01 ORF, IGLV7-43*02 ORF, IGLV(I)-42*01 P, IGLV7-35*01 P, IGLV7-35*02 P, IGLV(I)-34-2*01 P, IGLV(I)-34-1*01 P, IGLV2-34*01 P, IGLV2-33*01 F, IGLV3-32*01 ORF, IGLV3-31*01 P, IGLV3-30*01 P, IGLV3-29*01 P, IGLV2-28*01 P, IGLV3-27*01 F, IGLV3-27*02 F, IGLV3-26*01 P, IGLV3-26*02 P, IGLV(VI)-25-1*01 P, IGLV3-25*01 ORF, IGLV3-25*02 F, IGLV(II)-24-5*01 P, IGLV2-24-4*01 F, IGLV(VI)-24-3*01 P, IGLV3-24-2*01 F, IGLV(II)-24-1*01 P, IGLV3-24*01 P, IGLV3-24*02 P, IGLV2-23*01 F, IGLV(VI)-22-1*01 P, IGLV3-22*01 F, IGLV3-21*01 F, IGLV3-21*02 P, IGLV(I)-20*01 P, IGLV(I)-20*02 P, IGLV3-19*01 F, IGLV2-18*01 F, IGLV2-18*02 F, IGLV3-17*01 P, IGLV(VI)-16-1*01 P, IGLV(VI)-16-1*02 P, IGLV3-16*01 F, IGLV(II)-15-1*01 P, IGLV3-15*01 P, IGLV2-14*01 F, IGLV3-13*01 P, IGLV3-13*02 P, IGLV3-12*01 F, IGLV(I)-11-1*01 P, IGLV(I)-11-1*02 P, IGLV2-11*01 F, IGLV4-10-1*01 P, IGLV3-10*01 F, IGLV3-10*02 F, IGLV(II)-9-1*01 P, IGLV3-9*01 P, IGLV3-9*02 F, IGLV2-8*01 ORF IGLV2-8*02 ORF, IGLV4-7-1*01 P, IGLV4-7-1*02 P, IGLV3-7*01 P, IGLV3-6*01 P, IGLV2-5*01 P, IGLV2-5*02 P, IGLV3-4*01 ORF, IGLV4-3*01 ORF, IGLV4-3*02 ORF, IGLV3-2*01 P, IGLV3-1*01 F, IGLV3-1*02 F.
- Addition of 7 genes and 7 IGLJ alleles (5 F, 2 ORF): IGLJ1*01 F, IGLJ2*01 F, IGLJ3*01 F, IGLJ4*01 ORF, IGLJ5*01 ORF, IGLJ6*01 F , IGLJ7*01 F.
- Addition of 7 genes and 7 IGLC alleles (5 F, 2 ORF): IGLC1*01 F, IGLC2*01 F, IGLC3*01 F, IGLC4*01 P, IGLC5*01 P, IGLC6*01 F , IGLC7*01 F.
- Addition of 1 gene and 2 VPREB1 alleles (2 F): VPREB1*01 F, VPREB1*02 F.

02 March 2023 - Update of the Homo sapiens (human) IGH reference directory:
- Addition of 36 IGHV alleles (5 F, 3 ORF, 28 P ): IGHV3-79*03 P, IGHV(II)-65-1*03 P, IGHV(II)-62-1*04 P, IGHV(II)-60-1*03 P, IGHV3-60*04 P, IGHV3-53*06 F, IGHV3-47*04 P, IGHV(III)-25-1*04 P, IGHV(III)-16-1*04 P, IGHV3-16*03 ORF, IGHV3-15*09 F, IGHV1-68*04 P, IGHV(III)-67-4*03 P, IGHV(III)-67-3*02 P, IGHV(II)-67-1*02 P, IGHV3-63*03 P, IGHV3-62*06 ORF, IGHV(II)-60-1*04 P, IGHV3-30-42*02 P, IGHV(II)-30-41*02 P, IGHV4-30-4*09 F, IGHV1-17*03 P, IGHV3-16*04 ORF, IGHV(II)-15-1*02 P, IGHV1-14*03 P, IGHV(II)-46-1*02 P, IGHV(II)-43-1*03 P, IGHV(II)-51-2*02 P, IGHV8-51-1*05 P, IGHV3-42*04 P, IGHV(II)-30-51*03 P, IGHV3-30-5*03 F, IGHV1-12*04 P, IGHV(III)-11-1*04 P, IGHV2-10*02 P and IGHV4-4*12 F.
- Addition of 10 IGHC allele (9 F, 1 P): IGHM*06 F, IGHA1*05 P, IGHG2*18 F, IGHE*05 F, IGHA2*05 F, IGHD*04 F, IGHM*07 F, IGHD*05 F, IGHG1*15 F and IGHA1*06 F.
- Update of 22 Homo sapiens IGHV and IGHC reference sequences in IMGT reference directory: IGHG3*11 F (IMGT000110), IGHG2*02 F (IMGT000110), IGHE*02 F (IMGT000110), IGHA2*01 F (IMGT000110), IGHG1*03 F (IMGT000110), IGHG1*02 F (IMGT000111), IGHV3-66*02 F (IMGT000111), IGHV3-65*01 P (IMGT000111), IGHV1-8*03 F (IMGT000111), IGHV3-62*02 P (IMGT000112), IGHV4-61*02 F (IMGT000112), IGHV1-45*03 F (IMGT000112), IGHG3*21 F (IMGT000112), IGHGP*02 F (IMGT000112), IGHV3-71*03 P (IMGT000128), IGHV3-53*04 F (IMGT000128), IGHV3-43*02 F (IMGT000128), IGHV3-13*03 F (IMGT000128), IGHV3-11*04 F (IMGT000128), IGHG3*14 F (IMGT000128), IGHG2*03 F (IMGT000128) and IGHG4*01 F (IMGT000128).
- Update of 1 Homo sapiens (human) IGHC reference sequences in IMGT reference directory: IGHG4*08 (IMGT000112): update of functionality: initially F, now P.

28 February 2023 - Update of the Lemur catta (ring-tailed lemur) IGH reference directory:
- Update of the Lemur catta (ring-tailed lemur) IGHV gene and allele functionalities: Functionality of IGHV3-32*01 is P.

14 February 2023 - Update of the Pongo abelii (Sumatran orangutan) IGK reference directory :
- Addition of new IGKV genes: IGKV(II)-5-1*01 (P), IGKV(II)-13-1*01 (P), IGKV(II)-14-1*01 (P), IGKV(II)-43-1*01 (P), IGKV(II)-54-1*01, IGKV(II)-61-1*01.

13 February 2023 - Update of the Mus musculus (mouse) TRG reference directory :
- Addition of 1 TRGC allele sequence : TRGC*03 (ORF).
- Addition of 1 TRGV gene and 1 allele sequence : TRGVA*01 (P).

02 February 2023 - Update of the Lemur catta (ring-tailed lemur) IGH reference directory:
- Update of the Lemur catta (ring-tailed lemur) IGHD gene and allele functionalities: Functionality of IGHD6-6*01 is ORF.
- Update of the Lemur catta (ring-tailed lemur) IGHJ gene and allele functionalities: Functionality of IGHJ2*01 is F.

20 January 2023 - Update of the Homo sapiens (Human) IGH reference directory :
- Addition of 26 IGHV gene alleles (1 F, 24 P, 1 ORF): IGHV3-38-3*02 ORF, IGHV7-34-1*04 P, IGHV3-33*09 F, IGHV3-32*02 P, IGHV3-30-2*02 P, IGHV3-19*02 P, IGHV4-80*03 P, IGHV3-76*03 P, IGHV(III)-25-1*03 P, IGHV(II)-22-1D*02 P, IGHV3-75*02 P, IGHV(II)-65-1*02 P, IGHV3-62*05 P, IGHV(II)-53-1*03 P, IGHV5-51*08 P, IGHV(III)-38-1D*02 P, IGHV(III)-38-1*04 P, IGHV3-33-2*02 P, IGHV(II)-33-1*03 P, IGHV(III)-16-1*03 P, IGHV(II)-12-1*03 P, IGHV1-12*03 P, IGHV4-31*12 P, IGHV(III)-11-1*03 P, IGHV4-4*11 P, IGHV(II)-74-1*02 P.
- Addition of 6 IGHC gene alleles (3 F, 3 P): IGHA1*04 F, IGHD*03 F, IGHM*05 F, IGHGP*05 P, IGHA2*04 P, IGHEP1*06 P.

13 January 2023 - Update of the Lemur catta (ring-tailed lemur) IGH reference directory :
- Addition of 4 IGHD genes and 4 alleles (1 F, 3 ORF): IGHD3-8*01 F, IGHD6-9*01 ORF, IGHD4-10*01 ORF, IGHD6-11*01 ORF.

04 January 2023 - Update of the Mus musculus (mouse) IGK reference directory :
- Addition of 1 IGKV allele sequence : IGKV8-28*03 (F).

21 December 2022 - Update of the Mus musculus (mouse) TRA reference directory :
- Update of 1 TRAJ gene reference sequence - Addition of 6 nt at 3' end : TRAJ54*01 (P).

16 December 2022 - Update of the Mus musculus (mouse) IGK reference directory :
- Addition of 4 IGKV genes and 5 IGKV alleles (5 P): IGKV6-23-2*01 (P), IGKV13-71-1*02 (P), IGKV(I)-91-1*01 (P), IGKV(II)-14-1*01 (P), IGKV(II)-134-2*01 (P).

05 December 2022 - Update of the Pongo abelii (sumatran orangutan) IGK reference directory :
- Removal of 4 IGKV gapped sequence: IGKV2-25*01 P, IGKV2-53*01 P, IGKV9-68*01 P, IGKV9-71*01 P.

24 November 2022 - Creation of the Homo sapiens (human) IGH reference directory :
- Addition of 3 IGHV genes and 3 alleles (3 P): IGHV3-29*02 P, IGHV(II)-12-1*02 P, IGHV(III)-11-1*02 P.
- Addition of 3 IGHD genes and 3 alleles (3 F, 1 ORF): IGHD3-10*03 F, IGHD3-16*03 F, IGHD5-18*02 ORF.
- Addition of 5 IGHC genes and 5 allele (3 F, 1 P): IGHGP*04 F, IGHEP1*05 P, IGHG4*09 F, IGHG4a*01 F.

04 November 2022 - Update of the Mus musculus (mouse) TRAV reference directory :
- Addition of 1 TRAV gene allele (1 F): TRAV14-3*05 (F) (strain 129/SvJ).

26 October 2022 - Creation of the Gorilla gorilla gorilla (western lowland gorilla) IGK reference directory :
- Addition of 43 IGKV genes and 60 alleles (29 F, 28 P, 3 ORF): IGKV1-49*01 F, IGKV1-49*02 F, IGKV3-48*01 P, IGKV3-48*02 P, IGKV2-47*01 P, IGKV2-46*01 ORF, IGKV2-45*01 F, IGKV2-45*02 P, IGKV1-44*01 ORF, IGKV1-44*02 P, IGKV2-40*01 P, IGKV2-40*02 F, IGKV1-39*01 F, IGKV2-38*01 P, IGKV2-38*02 P, IGKV1-37*01 F, IGKV2-36*01 P, IGKV1-35*01 P, IGKV1-35*02 P, IGKV3-34*01 P, IGKV1-33*01 F, IGKV1-32*01 P, IGKV1-32*02 P, IGKV3-31*01 P, IGKV2-30*01 F, IGKV2-29*01 P, IGKV2-24*01 F, IGKV2-23*01 P, IGKV1-22*01 P, IGKV6-21*01 F, IGKV3-20*01 F, IGKV2-19*01 P, IGKV2-18*01 P, IGKV6-41*01 ORF, IGKV1-17*01 F, IGKV3-15*01 F, IGKV3-15*02 F, IGKV2-14*01 P, IGKV1-13*01 F, IGKV1-13*02 F, IGKV1-12*01 F, IGKV3-11*01 F, IGKV2-10*01 P, IGKV2-10*02 P, IGKV1-42*01 F, IGKV1-42*02 P, IGKV1-43*01 F, IGKV1-43*02 F, IGKV1-8*01 F, IGKV3-7*01 F, IGKV1-6*01 F, IGKV1-5*01 F, IGKV1-5*02 P, IGKV2-4*01 P, IGKV2-4*02 P, IGKV7-3*01 F, IGKV7-3*02 F, IGKV5-2*01 F, IGKV4-1*01 F, IGKV4-1*02 P.
- Addition of 5 IGKJ genes and 6 alleles (6 F): IGKJ1*01 F, IGKJ2*01 F, IGKJ3*01 F, IGKJ4*01 F, IGKJ5*01 F, IGKJ5*02 F.
- Addition of 1 IGKC genes and 1 allele (1 F): IGKC*01 F.

21 October 2022 - Update of the Gorilla gorilla gorilla (western lowland gorilla) IGHV reference directory :
- Update of the IMGT numbering for Gorilla gorilla gorilla (western lowland gorilla) IGHV in IMGT/GENE-DB reference directory sets: Removing of gap position 64.1 in "F+ORF+in-frame P with IMGT gaps" FASTA sequences (Nucleotides, Amino acids).

21 October 2022 - Update of the Heterocephalus glaber (naked-mole-rat) TRDV reference directory:
- Update of IMGT gaps (removal of the additional positions 79A, 79B, 79C, 79D in FR3-IMGT).
- Removal of TRDV1-4*01 gene allele.
6 October 2022 - Update of the Homo sapiens (human) IGK reference directory :
- Addition of 2 nucleotides in 3' reference sequence: IGKV2D-18*01 P.

03 October 2022 - Update of the Mus musculus (House mouse) IGL reference directory :
- Addition of 1 IGLC allele (F): IGLC4*02 F.
- Addition of 1 IGLJ gene (F): IGLJ2P*01 F.

29 September 2022 - Update of the Lemur catta (Ring-tailed lemur) IGKV reference directory :
- Addition of 5 IGKV alleles (3 F, 2 P): IGKV2-6*03 F, IGKV2-10*03 F, IGKV2-14*03 F, IGKV3-16*03 P, IGKV(II)-7*03 P.

28 September 2022 - Creation of the Lemur catta (ring-tailed lemur) IGH reference directory :
- Addition of 4 IGHC genes and 4 alleles (3 F, 1 P): IGHM*01 P, IGHG1*01 F, IGHE*01 F, IGHA*01 F.

27 September 2022 - Creation of the Pongo abelii (Sumatran Orangutan) IGK reference directory :
- Addition of 71 IGKV genes and 71 alleles (35 F, 4 ORF, 38 P) on chromosome 2A: IGKV9-71*01P, IGKV1-70*01P, IGKV3-69*01P, IGKV9-68*01P, IGKV1-67*01F, IGKV2-66*01P, IGKV1-65*01P, IGKV2-64*01P, IGKV2-63*01P, IGKV9-62*01P, IGKV2-61*01F, IGKV(II)-60*01P, IGKV(II)-59*01P, IGKV1-58*01P, IGKV3-57*01P, IGKV2-56*01P, IGKV2-55*01P, IGKV1-54*01P, IGKV2-53*01P, IGKV1-52*01ORF, IGKV3-51*01P, IGKV2-50*01F, IGKV2-49*01F, IGKV1-48*01F, IGKV1-47*01P, IGKV3-46*01P, IGKV2-45*01F, IGKV2-44*01P, IGKV2-43*01F, IGKV(II)-42*01P, IGKV1-41*01F, IGKV(II)-40*01P, IGKV2-39*01P, IGKV2-38*01F, IGKV3-37*01P, IGKV2-36*01P, IGKV1-35*01,P, IGKV6-34*01F, IGKV3-33*01F, IGKV2-32*01P, IGKV1-31*01P, IGKV6-30*01ORF, IGKV(II)-29*01P, IGKV1-28*01,F, IGKV1-27*01,F, IGKV3-26*01,F, IGKV2-25*01,P, IGKV1-24*01,F, IGKV1-23*01,ORF, IGKV1-22*01,F, IGKV3-21*01,F, IGKV2-20*01P, IGKV1-19*01ORF, IGKV1-18*01F, IGKV1-17*01F, IGKV1-16*01F, IGKV3-15*01F, IGKV1-14*01P, IGKV1-13*01F, IGKV3-12*01F, IGKV2-11*01P, IGKV1-10*01P, IGKV1-9*01F, IGKV1-8*01F, IGKV3-7*01F, IGKV6-6*01P, IGKV1-5*01F, IGKV2-4*01P, IGKV7-3*01F, IGKV5-2*01F, IGKV4-1*01F.
- Addition of 5 IGKJ genes and 5 alleles (4F, 1P) on chromosome 2A:IGKJ1*01F, IGKJ2*01F, IGKJ3*01F, IGKJ4*01F, IGKJ5*01P.
- Addition of 1 IGKC gene and 1 allele on chromosome 2A:IGKC*01F.

26 September 2022 - Update of the Homo sapiens (human) IGK reference directory :
- Update of 2 IGKV reference sequence (1 F, 1 P): IGKV3D-31*02 P, IGKJ2*04 F.
- Addition of 2 IGKV alleles (2 P): IGKV2-38*02 P, IGKV2-36*02 P.

29 August 2022 - Update of the Mus musculus (mouse) TRA/D reference directory :
- Update of the Mus musculus (mouse) TRA reference directory : TRAV12D-3*04, TRAV5-4*01, TRDV1*02 are functional.
- Addition of TRAV alleles on chromosome 14 (43 F, 4 ORF, 13 P): TRAV1*02 F, TRAV3-1*03 F, TRAV3-2*02 P, TRAV3-4*02 F, TRAV3D-2*02 P, TRAV4-1*02 P, TRAV4-3*03 F, TRAV4-4/DV10*02 F, TRAV4D-2*02 P, TRAV4D-3*06 F, TRAV5-1*02 F, TRAV5-2*02 P, TRAV5-4*02 F, TRAV5D-3*02 P, TRAV5D-2*02 P, TRAV6D-6*02 F, TRAV6D-5*02 F, TRAV6D-3*03 F, TRAV6-7/DV9*04 F, TRAV6-6*04 F, TRAV6-2*02 F, TRAV6-1*03 F, TRAV7-1*02 F, TRAV7-5*03 F, TRAV7-6*02 F, TRAV7D-2*02 F, TRAV7D-3*03 F, TRAV7D-5*02 F, TRAV8-2*02 P, TRAV9-2*02 F, TRAV9-4*02 F, TRAV9D-1*03 F, TRAV9D-2*05 ORF, TRAV9D-3*03 F, TRAV10*02 F, TRAV10D*03 F, TRAV11D*02 ORF, TRAV12-1*06 F, TRAV12-2*02 F, TRAV12-3*05 F, TRAV12-4*03 P, TRAV12D-1*06 F, TRAV12D-3*04 F, TRAV13D-2*03 F, TRAV13D-1*04 F, TRAV13-4/DV7*02 F, TRAV13-1*02 F, TRAV13-2*03 F, TRAV13-3*03 P, TRAV14-3*04 F, TRAV15D-1/DV6D-1*07 F, TRAV15-3*02 P, TRAV15-2/DV6-2*02 F, TRAV16*06 F, TRAV17*02 F, TRAV18*02 ORF, TRAV19*03 F, TRAV21/DV12*03 ORF, TRAV22*02 P, TRAV23*02 P.
- Addition of TRAJ alleles on chromosome 14 (5 F, 1 ORF, 3 P): TRAJ8*02 P, TRAJ9*02 F, TRAJ12*02 F, TRAJ24*02 F, TRAJ25*02 ORF, TRAJ26*01 F, TRAJ46*02 P, TRAJ47*02 F, TRAJ51*02 P.
- Addition of TRDV alleles on chromosome 14 (2 F, 1 P): TRDV1*02 F, TRDV2-1*02 F, TRDV3*02 P.
- Addition of TRDV allele on chromosome 14 (1 F): TRDD1*02 F.

22 July 2022 - Creation of the Lemur catta (ring-tailed lemur) IGH reference directory :
- Addition of 84 IGHV genes and 84 alleles (57 F, 2 ORF, 25 P): IGHV(II)-81*01 P, IGHV3-80*01 P, IGHV3-79*01 F, IGHV3-78*01 F, IGHV3-77*01 F, IGHV4-76*01 P, IGHV3-75*01 F, IGHV3-74*01 F, IGHV4-73*01 P, IGHV3-72*01 F, IGHV3-71*01 F, IGHV3-70*01 F, IGHV3-69*01 F, IGHV4-68*01 P, IGHV3-67*01 F, IGHV5-66*01 P, IGHV3-65*01 F, IGHV3-64*01 F, IGHV4-63*01 P, IGHV3-62*01 F, IGHV3-61*01 F, IGHV2-37D*01 P, IGHV3-60*01 F, IGHV4-59*01 P, IGHV3-58*01 F, IGHV3-57*01 F, IGHV3-56*01 P, IGHV5-55*01 P, IGHV3-54*01 F, IGHV4-53*01 P, IGHV3-52N*01 F, IGHV3-52D*01 F, IGHV3-52*01 F, IGHV3-51*01 F, IGHV9-50*01 ORF, IGHV3-49*01 F, IGHV3-48*01 F, IGHV3-47*01 F, IGHV3-46*01 F, IGHV(II)-45*01 P, IGHV1-44*01 ORF, IGHV4-43*01 P, IGHV3-42*01 F, IGHV3-41*01 F, IGHV3-40*01 P, IGHV4-39*01 P, IGHV3-38*01 F, IGHV2-37*01 P, IGHV3-36*01 F, IGHV4-35*01 P, IGHV3-34-1*01 F, IGHV3-33*01 F, IGHV3-32*01 F, IGHV3-31*01 F, IGHV3-30*01 F, IGHV3-29*01 F, IGHV3-28*01 F, IGHV3-27*01 F, IGHV3-26*01 F, IGHV3-25*01 F, IGHV3-24*01 F, IGHV3-23*01 F, IGHV4-22*01 P, IGHV3-21*01 F, IGHV3-20*01 F, IGHV4-19*01 P, IGHV3-18*01 F, IGHV5-17*01 P, IGHV3-16*01 F, IGHV3-15*01 F, IGHV3-14*01 F, IGHV3-13*01 F, IGHV3-12*01 F, IGHV3-11*01 F, IGHV3-10*01 F, IGHV3-9*01 F, IGHV4-8*01 P, IGHV3-7*01 F, IGHV3-6*01 F, IGHV4-5*01 P, IGHV3-4*01 P, IGHV3-3*01 F, IGHV3-2*01 F, IGHV(II)-1*01 P.
- Addition of 7 IGHD genes and 7 alleles (4 F, 3 ORF): IGHD2-1*01 F, IGHD3-2*01 ORF, IGHD1-3*01 F, IGHD3-4*01 ORF, IGHD5-5*01 ORF, IGHD6-6*01 F, IGHD1-7*01 F.
- Addition of 7 IGHJ genes and 7 alleles (4 F, 3 ORF): IGHJ1*01 ORF, IGHJ2*01 ORF, IGHJ3*01 ORF, IGHJ4*01 F, IGHJ5-1*01 F, IGHJ6*01 F, IGHJ5-2*01 F.

17 June 2022 - Creation of the Gorilla gorilla gorilla (western lowland gorilla) TRG reference directory :
- Addition of 15 TRGV genes and 23 alleles (8 F, 4 ORF, 11 P): TRGV1*01 ORF, TRGV2*01 F, TRGV3*01 F, TRGV3*02 F, TRGV4*01 F, TRGV4*02 F, TRGV4P*01 P, TRGV5*01 P, TRGV5*02 F, TRGV6*01 P, TRGV6*02 P, TRGV7*01 P, TRGV8*01 F, TRGV8*02 F, TRGVA*01 P, TRGVA*02 P, TRGV9*01 ORF, TRGV9*02 ORF, TRGV10*01 ORF, TRGVB*01 P, TRGVB*02 P, TRGVC*01 P, TRGVD*01 P.
- Addition of 5 TRGJ genes and 5 alleles (2 F, 3 ORF): TRGJP1*01 ORF, TRGJP*01 ORF, TRGJ1*01 F, TRGJP2*01 ORF, TRGJ2*01 F.
- Addition of 2 TRGC genes and 4 alleles (2 F, 2 P): TRGC1*01 F, TRGC1*02 P, TRGC2*01 F, TRGC2*02 P.

15 June 2022 - Creation of the Lemur catta (Ring-tailed lemur) IGKV reference directory :
- Addition of 17 IGKV genes and 30 alleles (18 F, 12 P): IGKV(II)-7*01 P, IGKV(II)-7*02 P, IGKV1-15*01 P, IGKV2-10*01 F, IGKV2-10*02 F, IGKV2-11*01 P, IGKV2-11*02 P, IGKV2-12*01 F, IGKV2-12*02 F, IGKV2-13*01 F, IGKV2-13*02 F, IGKV2-14*01 F, IGKV2-14*02 F, IGKV2-4*01 P, IGKV2-4*02 P, IGKV2-6*01 F, IGKV2-6*02 F, IGKV2-9*01 P, IGKV2-9*02 P, IGKV3-16*01 P, IGKV3-16*02 P, IGKV4-1*01 F, IGKV4-1*02 F, IGKV4-5*01 F, IGKV4-5*02 F, IGKV5-2*01 F, IGKV6-8*01 F, IGKV6-8*02 F, IGKV8-3*01 F, IGKV9-17*01 F.
- Addition of 5 IGKJ genes and 7 alleles (5 F, 2 ORF): IGKJ1*01 F, IGKJ2*01 F, IGKJ2*02 F, IGKJ3*01 F, IGKJ4*01 F, IGKJ5*01 ORF, IGKJ5*02 ORF, .
- Addition of 1 IGKC genes and 2 alleles (2 F): IGKC*01 F, IGKC*02 F.

01 February 2022 - Update of the Homo sapiens (human) IGH reference directory:
- IMGT000035 is the IMGT reference sequence for IGHV2-70*01 F, whereas the allele sequence L21969 has become a sequence of the literature.
- AB019437 is the IMGT reference sequence for IGHV3-74*01 F, whereas the allele sequence L33851 has become a sequence of the literature.
- AC245166 is the IMGT reference sequence for IGHV4-30-2*01 F, whereas the allele sequence L10089 has become a sequence of the literature.

28 January 2022 - Update of the Macaca mulatta (Rhesus monkey) IGH reference directory:
- Update of the Macaca mulatta (Rhesus monkey) IGHV gene and allele functionalities: Functionality of IGHV3-103*02 is ORF.

28 January 2022 - Update of the Macaca mulatta (Rhesus monkey) IGK reference directory:
- Update of the Macaca mulatta (Rhesus monkey) IGKJ gene and allele functionalities: Functionality of IGKJ5*01 is F.

05 January 2022 - Update of the Bos taurus (bovine) TRB reference directory:
- Update of the Bos taurus (bovine) TRBV gene and allele functionalities: Functionality of TRBV19-1*01 is F.
- Update of the Bos taurus (bovine) TRBJ gene and allele functionalities: Functionality of TRBJ2-7*01 is F.

17 December 2021 - Update of the Heterocephalus glaber (Naked mole-rat) TRA/TRD reference directory:
- Addition of 93 TRAV genes and 108 alleles (47 F, 6 ORF, 55 P): TRAV1*01 F, TRAV4*01 F, TRAV5-1*01 F, TRAV5-2*01 P, TRAV5-3*01 P, TRAV8-1*01 F, TRAV8-2*01 F, TRAV8-3*01 F, TRAV8-4*01 P, TRAV8-5*01 P, TRAV8-6*01 F, TRAV8-7*01 P, TRAV9-1*01 F, TRAV9-2*01 F, TRAV9-3*01 F, TRAV9-3*02 F, TRAV9-4*01 P, TRAV9-5*01 F, TRAV9-5*02 F, TRAV9-6*01 F, TRAV9-7*01 F, TRAV9-8*01 F, TRAV10*01 P, TRAV11-1*01 F, TRAV11-2*01 P, TRAV12-1*01 P, TRAV12-2*01 F, TRAV12-2*02 F, TRAV12-3*01 F, TRAV12-4*01 F, TRAV12-5*01 F, TRAV12-6*01 F, TRAV12-7*01 F, TRAV12-8*01 P, TRAV12-8*02 ORF, TRAV12-9*01 F, TRAV12-9*02 P, TRAV13-1*01 P, TRAV13-1*02 P, TRAV13-2*01 F, TRAV13-3*01 P, TRAV14-1*01 P, TRAV14-2*01 F, TRAV14-3*01 P, TRAV14-3*02 P, TRAV14-4*01 P, TRAV17-1*01 ORF, TRAV17-2*01 F, TRAV18-1*01 ORF, TRAV18-2*01 P, TRAV19-1*01 F, TRAV19-2*01 P, TRAV19-3*01 P, TRAV21*01 P, TRAV22-1*01 F, TRAV22-2*01 F, TRAV22-3*01 P, TRAV22-4*01 F, TRAV22-5*01 P, TRAV22-6*01 P, TRAV23-1*01 P, TRAV23-2*01 F, TRAV23-3*01 F, TRAV23-4*01 F, TRAV23-5*01 P, TRAV25-1*01 P, TRAV25-1*02 ORF, TRAV25-2*01 P, TRAV25-3*01 F, TRAV27*01 P, TRAV28*01 ORF, TRAV29-1*01 F, TRAV29-2*01 P, TRAV30S1*01 P, TRAV31S1*01 P, TRAV32S1*01 P, TRAV33S1*01 ORF, TRAV34-1*01 F, TRAV34S1*01 F, TRAV34S2*01 F, TRAV35-1*01 F, TRAV35S1*01 F, TRAV35S1*02 F, TRAV35S2*01 P, TRAV35S3*01 P, TRAV36S1*01 P, TRAV36S1*02 P, TRAV38-1*01 P, TRAV38S1*01 P, TRAV38S2*01 F, TRAV38S3*01 P, TRAV38-5*01 F, TRAV39*01 P, TRAV40*01 P, TRAV41*01 P, TRAV43*01 F, TRAV46*01 P, TRAVA*01 P, TRAVA*02 P, TRAVB*01 P, TRAVC*01 P, TRAVC*02 P, TRAVD*01 P, TRAVD*02 P, TRAVE*01 P, TRAVF*01 P, TRAVF*02 P.
- Addition of 59 TRAJ genes and 59 alleles (42 F, 12 ORF, 5 P): TRAJ2*01 P, TRAJ3*01 ORF, TRAJ4*01 F, TRAJ5*01 F, TRAJ6*01 ORF, TRAJ7*01 F, TRAJ8*01 F, TRAJ9*01 F, TRAJ10*01 F, TRAJ11*01 F, TRAJ12*01 ORF, TRAJ13*01 F, TRAJ14*01 F, TRAJ15*01 F, TRAJ16*01 F, TRAJ17*01 F, TRAJ18*01 ORF, TRAJ19*01 P, TRAJ20*01 F, TRAJ21*01 ORF, TRAJ22*01 F, TRAJ23*01 ORF, TRAJ24*01 F, TRAJ25*01 F, TRAJ26*01 F, TRAJ27*01 F, TRAJ28*01 F, TRAJ29*01 F, TRAJ30*01 F, TRAJ31*01 F, TRAJ32*01 F, TRAJ33*01 F, TRAJ34*01 F, TRAJ35*01 ORF, TRAJ36*01 F, TRAJ37*01 ORF, TRAJ38*01 ORF, TRAJ39*01 F, TRAJ40*01 F, TRAJ41*01 F, TRAJ42*01 ORF, TRAJ43*01 F, TRAJ44*01 F, TRAJ45*01 F, TRAJ46*01 P, TRAJ47*01 F, TRAJ48*01 F, TRAJ49*01 F, TRAJ50*01 F, TRAJ51*01 ORF, TRAJ52*01 F, TRAJ53*01 F, TRAJ54*01 F, TRAJ56*01 F, TRAJ57*01 F, TRAJ58*01 F, TRAJ59*01 P, TRAJ60*01 P, TRAJ61*01 ORF.
- Addition of 1 TRAC genes and 1 alleles (1 F): TRAC*01 F.
- Addition of 13 TRDV genes and 13 alleles (3 F, 3 ORF, 7 P): TRDV1-1*01 P, TRDV1-2*01 ORF, TRDV1-3*01 P, TRDV1-4*01 ORF, TRDV1-5*01 F, TRDV1-6*01 F, TRDV2*01 P, TRDV3*01 ORF, TRDV4*01 P, TRDV5*01 F, TRDVA*01 P, TRDVB-1*01 P, TRDVB-2*01 P.
- Addition of 4 TRDJ genes and 4 alleles (1 F, 2 ORF, 1 P): TRDJ1*01 F, TRDJ2*01 ORF, TRDJ3*01 P, TRDJ1-4*01 ORF.
- Addition of 3 TRDD genes and 3 alleles (2 F, 1 ORF): TRDD1*01 ORF, TRDD2*01 F, TRDD3*01 F.
- Addition of 1 TRDC genes and 1 alleles (1 F): TRDC*01 F.

13 December 2021 - Update of the Oncorhynchus mykiss (rainbow trout) IGH reference directory: integration of the IGH V, D, and J genes and alleles of the Arlee strain:
- Addition of 22 IGHV genes and 72 alleles (42 F, 10 ORF, 20 P): IGHV10-47*02 F, IGHV10D-7*02 F, IGHV10D-9*02 F, IGHV11-25*02 F, IGHV11-28-3*01 F, IGHV11-47-2*01 F, IGHV11-47-5*01 ORF, IGHV1-18*02 F, IGHV1-21*02 F, IGHV1-2*03 ORF, IGHV1-28-2*01 P, IGHV12D-36*02 F, IGHV12D-71*02 F, IGHV1-39*02 F, IGHV1-39-5*01 F, IGHV1-41*02 P, IGHV1-42*02 F, IGHV14-33*02 F, IGHV1-47-4*01 F, IGHV15-48*02 F, IGHV15D-66*02 ORF, IGHV15D-69-3*01 F, IGHV16-14*02 ORF, IGHV16-38*02 ORF, IGHV16-39-3*01 ORF, IGHV16-39-4*01 P, IGHV16-50*01 P, IGHV16-9*03 P, IGHV16D-79*02 P, IGHV1D-14-3*01 F, IGHV1D-22*02 P, IGHV1D-4*02 ORF, IGHV1D-4-2*02 P, IGHV1D-73*02 F, IGHV1D-8-10*01 F, IGHV1D-8-5*01 F, IGHV1D-8-7*01 F, IGHV2-27*02 P, IGHV2-28*02 F, IGHV2D-11*02 F, IGHV2D-8-1*01 F, IGHV3-20*02 F, IGHV4-22*02 P, IGHV4D-13*02 P, IGHV4D-23*02 F, IGHV4D-60*02 F, IGHV4D-72*02 P, IGHV4D-8-4*01 P, IGHV6-35*02 F, IGHV6-4*02 F, IGHV6D-27*02 P, IGHV6D-5*02 F, IGHV6D-64*02 P, IGHV6D-76*02 F, IGHV7D-17-1*02 F, IGHV7D-23-1*02 ORF, IGHV7D-61*02 ORF, IGHV7D-8-8*01 F, IGHV8-11*02 P, IGHV8-19*02 ORF, IGHV8-39-2*01 F, IGHV8-40*02 F, IGHV8-47-3*01 P, IGHV8-5*03 F, IGHV8D-40-3*01 P, IGHV8D-76-1*01 P, IGHV9-15*02 F, IGHV9-22-2*01 F, IGHV9-23*02 F, IGHV9-34*02 P, IGHV9-45*02 F, IGHV9D-2*02 F
- Addition of 5 IGHD genes and 6 alleles (6 F): IGHD1D*02 F, IGHD1T3D*01 F, IGHD2T2D*01 F, IGHD2T3D*01 F, IGHD3T3D*01 F, IGHD4T3D*01 F.
- Addition of IGHJ genes and 5 alleles (5F): IGHJ1T3D*01 F, IGHJ2T3D*01 F, IGHJ3D*02 F, IGHJ4*02 F, IGHJ6D*02 F.
- Addition of sequences from the literature for : IGHD1*02, IGHD1T1*01, IGHD1T2*02, IGHD2*01, IGHD2D*01, IGHD2T1*01, IGHD2T1D*01, IGHD2T2*01, IGHD3*01, IGHD3D*01, IGHD3T1*01, IGHD3T1D*01, IGHD3T2*01, IGHD4*01, IGHD4D*01, IGHD4T1D*01, IGHD5*01, IGHD5D*01, IGHD6*01, IGHD6D*01, IGHJ1*01, IGHJ1T1*01, IGHJ1T1D*01, IGHJ1T2*01, IGHJ2*01, IGHJ2T1*01, IGHJ2T1D*01, IGHJ2T2*02, IGHJ3*01, IGHJ4D*01, IGHJ5*02, IGHJ5D*01, IGHJ7D*01, IGHV1-13*01, IGHV1-36*01, IGHV1D70*01, IGHV2-8*01, IGHV3-31*01, IGHV10-26*01, IGHV16-37*01, IGHV1D-12*01, IGHV8-46*01

01 December 2021 - Creation of the Bos taurus (bovine) TRB reference directory: :
- Addition of 123 TRGV genes and 124 alleles (61 F, 10 ORF, 52 P): TRBV1*01 F, TRBV2*01 P, TRBV3*01 F, TRBV4*01 F, TRBV5-1*01 P, TRBV5-2*01 F, TRBV5-3*01 F, TRBV5-4*01 P, TRBV5-5*01 P, TRBV5-5D*01 P, TRBV5-6*01 F, TRBV5-7*01 F, TRBV5-8*01 P, TRBV5-9*01 P, TRBV5-10*01 P, TRBV5-11*01 F, TRBV5-11D*01 F, TRBV5-12*01 F, TRBV5-13*01 P, TRBV5-13D*01 P, TRBV5-14*01 P, TRBV5-15*01 F, TRBV5-16*01 P, TRBV5-17*01 F, TRBV5-18*01 P, TRBV5-19*01 P, TRBV5-20*01 F, TRBV5-21*01 F, TRBV5-22*01 F, TRBV6-1*01 ORF, TRBV6-2*01 F, TRBV6-3*01 P, TRBV6-4*01 P, TRBV6-5*01 P, TRBV6-6*01 P, TRBV6-7*01 P, TRBV6-8*01 P, TRBV6-9*01 F, TRBV6-10*01 P, TRBV6-11*01 F, TRBV6-12*01 ORF, TRBV6-13*01 F, TRBV6-14*01 ORF, TRBV6-15*01 F, TRBV6-15D*01 F, TRBV6-16*01 P, TRBV6-17*01 ORF, TRBV6-18*01 ORF, TRBV6-19*01 F, TRBV6-20*01 F, TRBV6-21*01 F, TRBV6-22*01 ORF, TRBV6-23*01 P, TRBV6-24*01 F, TRBV6-25*01 ORF, TRBV6-26*01 F, TRBV6-27*01 F, TRBV6-29*01 F, TRBV7-1*01 F, TRBV7-2*01 F, TRBV8*01 P, TRBV10*01 P, TRBV11*01 P, TRBV12-1*01 F, TRBV12-2*01 F, TRBV13*01 P, TRBV14*01 F, TRBV15*01 F, TRBV16*01 F, TRBV18-1*01 P, TRBV18-2*01 P, TRBV18-3*01 P, TRBV18-4*01 P, TRBV19-1*01 ORF, TRBV19-2*01 P, TRBV19-3*01 P, TRBV19-4*01 P, TRBV19-5*01 P, TRBV19-6*01 ORF, TRBV20-1*01 F, TRBV20-2*01 F, TRBV20-3*01 F, TRBV20-4*01 F, TRBV20-5*01 F, TRBV20-6*01 F, TRBV21-1*01 P, TRBV21-2*01 F, TRBV21-3*01 P, TRBV21-4*01 P, TRBV21-5*01 F, TRBV21-6*01 F, TRBV21-7*01 P, TRBV21-8*01 P, TRBV21-9*01 P, TRBV21-10*01 P, TRBV21-11*01 ORF, TRBV21-12*01 F, TRBV21-13*01 P, TRBV21-14*01 P, TRBV21-15*01 F, TRBV21-16*01 F, TRBV21-17*01 F, TRBV21-18*01 F, TRBV21-19*01 F, TRBV21-20*01 P, TRBV21-21*01 P, TRBV21-22*01 F, TRBV21-23*01 F, TRBV22*01 F, TRBV23*01 P, TRBV24*01 P, TRBV25*01 F, TRBV26*01 F, TRBV27*01 F, TRBV28*01 F, TRBV29-1*01 P, TRBV29-2*01 F, TRBV29-3*01 F, TRBV29-4*01 F, TRBV29-5*01 F, TRBV30*01 F, TRBV30*02 F, TRBVA*01 P, TRBVB*01 P.
- Addition of 3 TRBD genes and 7 alleles (4 F, 3 P): TRBD1*01 F, TRBD2*01 F, TRBD3*01 F.
- Addition of 19 TRBJ genes and 22 alleles (14 F, 4 ORF, 1 P): TRBJ1-1*01 F, TRBJ1-2*01 F, TRBJ1-3*01 ORF, TRBJ1-4*01 F, TRBJ1-5*01 ORF, TRBJ1-6*01 ORF, TRBJ2-1*01 F, TRBJ2-1*02 F, TRBJ2-2*01 F, TRBJ2-3*01 F, TRBJ2-3*02 F, TRBJ2-4*01 F, TRBJ2-5*01 F, TRBJ2-6*01 F, TRBJ2-6*02 F, TRBJ2-7*01 ORF, TRBJ3-1*01 F, TRBJ3-2*01 F, TRBJ3-3*01 F, TRBJ3-4*01 F, TRBJ3-5*01 F, TRBJ3-6*01 P.
- Addition of 3 TRBC genes and 6 alleles (6 F): TRBC1*01 F, TRBC2*01 F, TRBC3*01 F, TRBC1*02 F, TRBC2*02 F, TRBC3*02 F.

01 December 2021 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of 8 IGHV new inferred alleles (8 F): IGHV1-69*20 (F) (OU596106), IGHV3-21*07 (F) (OU596107), IGHV3-30*20 (F) (OU596105), IGHV3-9*04 (F) (OU596108, see below), IGHV4-39*08 (F) (OU596110), IGHV4-39*09 (F) (OU596103), IGHV4-4*10 (F) (OU596101), IGHV4-61*11 (F) (OU596109) (IUIS NOM IMGT-NC_Report_2021-3-1117_Homsap_IGHV).
- Update of MN337621: previously assigned to IGHV3-9*01 (sequence from the literature), has now been assigned to IGHV3-9*04, following a nucleotide change in the EMBL flat file, t360 (version 1) > c (version 2) (IMGT unique numbering t307>c, Y103>H). MN33621 is IMGT reference sequence for IGHV3-9*04 F, whereas the inferred allele sequence OU596108 has become sequence of the literature.

29 October 2021 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of 1 IGHV new allele (ORF): IGHV8-51-1*04 (AC279961).
- Update of the IMGT/LIGM-DB reference sequences of Homo sapiens (human) IGHV1-69*02 (MG719325), IGHV3-25*03 (AC245166), IGHV3-52*02 (AC279961), IGHV3-63*02 (IMGT000058).

26 October 2021 - Creation of the Gorilla gorilla gorilla (western lowland gorilla) IGH reference directory :
- Addition of 9 IGHC genes and 12 alleles (4 F, 8P): IGHM*01 F, IGHD*01 F, IGHD*02 F, IGHG3A*01 P, IGHG3A*02 P, IGHG3B*01 P, IGHG3C*01 P, IGHG1*02 P, IGHG1*02 F, IGHEP1*01 P, IGHA1*03 P, IGHGP*02 P.

21 October 2021 - Creation of the Gorilla gorilla gorilla (western lowland gorilla) IGH reference directory :
- Addition of 151 IGHV genes and 221 alleles (56 F, 6 ORF, 159 P): IGHV(III)-82*01 P, IGHV7-81*01 ORF, IGHV4-80*01 F, IGHV4-80*02 F,IGHV3-79*01 P,IGHV3-79*02 P, IGHV(II)-78-1*01 P, IGHV5-78*01 P, IGHV(III)-76-1*01 P, IGHV3-76*01 P,IGHV3-76*02 P, IGHV3-75*01 P,IGHV3-75*02 P, IGHV(II)-74-1*01 P,IGHV(II)-74-1*02 P, IGHV3-74*01 F, IGHV3-73*01 F, IGHV3-72*01 F,IGHV3-72*02 ORF, IGHV3-71*01 F, IGHV2-70*01 F,IGHV2-70*02 P,IGHV1-69D*01 P,IGHV2-70D*01 P, IGHV1-69*01 F,IGHV1-69*02 P, IGHV1-68*01 P, IGHV(III)-67-4*01 P,IGHV(III)-67-4*02 P, IGHV(III)-67-3*01 P,IGHV(III)-67-3*02 P, IGHV(III)-67-2*01 P, IGHV(III)-67-1*01 P, IGHV1-67*01 P,IGHV1-67*02 P, IGHV3-66*01 F,IGHV3-66*02 F, IGHV(II)-65-1*01 P, IGHV3-65*01 P, IGHV3-64*01 F, IGHV3-63*01 P, IGHV(II)-62-1*01 P, IGHV3-62*01 F,IGHV3-62*02 P, IGHV4-61*01 F, IGHV4-61*02 F, IGHV3-60-6*01 P, IGHV4-60-5*01 P, IGHV(II)-60-4*01 P, IGHV3-60-3*01 P, IGHV4-60-2*01 P, IGHV(II)-60-1*01 P, IGHV(II)-60-1*02 P, IGHV3-60*01 P, IGHV3-60*02 P, IGHV4-59*01 F, IGHV1-58*01 ORF, IGHV3-57*01 P, IGHV7-56*01 P, IGHV4-55*01 F, IGHV3-54*01 P, IGHV(II)-53-1*01 P, IGHV(II)-53-1*02 P, IGHV3-53*01 F, IGHV3-53*02 F, IGHV3-52*01 P, IGHV(II)-51-2*01 P, IGHV8-51-1*01 P, IGHV5-51*01 ORF, IGHV3-50*01 P, IGHV(II)-49-1*01 P, IGHV(II)-49-1*02 P, IGHV3-49*01 F, IGHV3-48*01 F, IGHV3-48*02 P, IGHV(III)-47-1*01 P, IGHV3-47*01 P, IGHV3-47*02 P, IGHV(II)-46-1*01 P, IGHV(II)-46-1*02 P, IGHV1-46*01 F, IGHV1-45*01 F, IGHV(II)-44-2*01 P, IGHV(II)-44-2*02 P, IGHV(IV)-44-1*01 P, IGHV(IV)-44-1*02 P, IGHV(III)-44*01 P, IGHV(II)-43-1*01 P, IGHV(II)-43-1*02 P, IGHV3-43*01 F, IGHV3-43*02 P, IGHV3-42*01 P, IGHV3-41D*01 F, IGHV(II)-40-1D*01 P, IGHV7-40D*01 P, IGHV4-39D*01 P, IGHV3-41*01 P, IGHV(II)-40-1*01 P, IGHV7-40*01 P, IGHV4-39*01 F, IGHV1-38-4*01 P, IGHV(III)-38-1*01 P, IGHV3-38*01 F, IGHV3-37*01 P, IGHV3-37*02 P, IGHV3-36*01 P, IGHV3-36*02 P, IGHV3-35*01 P, IGHV3-35*02 P, IGHV7-34-1*01 P, IGHV4-34*01 F, IGHV3-33-2*01 P, IGHV3-33-2*02 P, IGHV(II)-33-1*01 P, IGHV(II)-33-1*02 P, IGHV3-33*01 F, IGHV3-33*02 F, IGHV3-32*01 P, IGHV3-32*02 P, IGHV(II)-31-1*01 P, IGHV4-31*01 F, IGHV3-30-52*01 P, IGHV(II)-30-51*01 P, IGHV3-30-5*01 F, IGHV3-30-42*01 P, IGHV(II)-30-41*01 P, IGHV(II)-30-41*02 P, IGHV4-30-4*01 F, IGHV4-30-4*02 P, IGHV3-30-33*01 P, IGHV3-30-33*02 P, IGHV(II)-30-32*01 P, IGHV(II)-30-32*02 P, IGHV3-30-3*01 F, IGHV3-30-3*02 F, IGHV3-30-22*01 P, IGHV3-30-22*02 P, IGHV(II)-30-21*01 P, IGHV(II)-30-21*02 P, IGHV4-30-2*01 F, IGHV4-30-2*02 P, IGHV3-30-2*01 P, IGHV3-30-2*02 P, IGHV(II)-30-1*01 P, IGHV(II)-30-1*02 P, IGHV3-30*01 F, IGHV3-30*02 P, IGHV3-29*01 P, IGHV3-29*02 P, IGHV(II)-28-1*01 P, IGHV(II)-28-1*02 P, IGHV2-26*01 F, IGHV(III)-25-1*01 P, IGHV(III)-25-1*02 P, IGHV3-25*01 P, IGHV3-25*02 P, IGHV1-24*01 P, IGHV1-24*02 P, IGHV3-23*01 F, IGHV(III)-22-2*01 P, IGHV(II)-22-1*01 P, IGHV3-22*01 F, IGHV3-21*01 F, IGHV3-21*02 F, IGHV(II)-20-1*01 P, IGHV(II)-20-1*02 P, IGHV3-20*01 F, IGHV3-20*02 P, IGHV3-19*01 P, IGHV3-19*02 P, IGHV1-18*01 P, IGHV1-17*01 P, IGHV(III)-16-1*01 P, IGHV3-16*01 P, IGHV(II)-15-1*01 P, IGHV(II)-15-1*02 P, IGHV3-15*01 F, IGHV3-15*02 P, IGHV1-14*01 P, IGHV1-14*02 P, IGHV(III)-13-1*01 P, IGHV(III)-13-1*02 P, IGHV3-13*01 F, IGHV3-13*02 P, IGHV(II)-12-1*01 P, IGHV(II)-12-1*02 P, IGHV1-12*01 P, IGHV1-12*02 P, IGHV(III)-11-1*01 P, IGHV(III)-11-1*02 P, IGHV3-11*01 F, IGHV3-11*02 F, IGHV2-10*01 P, IGHV3-9*01 F, IGHV3-9*02 P, IGHV1-8*01 F, IGHV1-8*02 P, IGHV3-7*01 F, IGHV3-7*02 P, IGHV(III)-5-2*01 P, IGHV(III)-5-1*01 P,IGHV2-5*01 ORF, IGHV(II)-4-2*01 P, IGHV7-4-1*01 F, IGHV7-4-1*02 P, IGHV(II)-4-8*01 P, IGHV(II)-4-7*01 P, IGHV4-4-6*01 ORF, IGHV7-4-5*01 F, IGHV(II)-4-4*01 P, IGHV(II)-4-4*02 P, IGHV(II)-4-3*01 P, IGHV4-4*01 F, IGHV1-3*01 F, IGHV1-3*02 F, IGHV(III)-2-1*01 P, IGHV(III)-2-1*02 P, IGHV1-2*01 F, IGHV(II)-1-1*01 P, IGHV(II)-1-1*02 P, IGHV6-1*01 F,.
- Addition of 9 IGHJ genes and 15 alleles (8 F, 2 ORF, 5 P): IGHJ1P*01 P, IGHJ1P*02 P, IGHJ1*01 F, IGHJ2*01 P, IGHJ2P*01 ORF, IGHJ2P*02 ORF, IGHJ3*01 F, IGHJ3*02 F, IGHJ4*01 F, IGHJ4*02 F, IGHJ5*01 F, IGHJ3P*01 P, IGHJ3P*02 P, IGHJ6*01 F, IGHJ6*02 F.
- Addition of 32 IGHD genes and 36 alleles (24 F, 11 ORF, 1 P): IGHD1-1*01 F, IGHD2-2*01 F, IGHD3-3*01 F, IGHD4-4*01 ORF, IGHD5-5*01 ORF, IGHD6-5-1*01 P, IGHD1-5-2*01 ORF, IGHD2-5-3*01 F, IGHD3-5-4*01 F, IGHD4-5-5*01 ORF, IGHD5-5-6*01 F, IGHD6-6*01 F, IGHD1-7*01 F, IGHD2-8*01 F, IGHD3-10*01 F, IGHD4-11*01 ORF, IGHD5-12*01 F, IGHD6-13*01 F, IGHD1-14*01 ORF, IGHD2-15*01 F, IGHD3-16*01 F, IGHD3-16*02 ORF, IGHD4-17*01 F , IGHD5-18*01 F, IGHD5-18*02 F, IGHD6-19*01 F, IGHD1-20*01 F, IGHD2-21*01 F, IGHD3-22*01 F, IGHD3-22*02 F, IGHD4-23*01 ORF, IGHD4-23*02 ORF, IGHD5-24*01 ORF, IGHD6-25*01 F, IGHD1-26*01 ORF, IGHD7-27*01 F.

06 October 2021 - Creation of the Heterocephalus glaber (Naked mole-rat) TRG reference directory:
- Addition of 15 TRGV genes and 16 alleles (1 F, 3 ORF, 12 P): TRGV1-1*01 F, TRGV1-2*01 P, TRGV1-3*01 P, TRGV1-3*02 P, TRGV1-4*01 P, TRGV1-5*01 P, TRGV2*01 P, TRGV3-1*01 ORF, TRGV3-2*01 ORF, TRGV4-1*01 P, TRGV4-2*01 ORF, TRGV4-3*01 P, TRGVA*01 P, TRGVB*01 P, TRGVC*01 P, TRGVD*01 P.
- Addition of 11 TRGJ genes and 12 alleles (1 F, 7 ORF, 4 P): TRGJ1-1*01 ORF, TRGJ1-2*01 F, TRGJ2-1*01 P, TRGJ3-1*01 ORF, TRGJ3-2*01 P, TRGJ3-3*01 ORF, TRGJ4-1*01 ORF, TRGJ4-1*02 ORF, TRGJ4-2*01 ORF, TRGJ5-1*01 P, TRGJ5-2*01P, TRGJ5-3*01 ORF
- Addition of 6 TRGC genes and 7 alleles (4 F, 3 P): TRGC1*01 P, TRGC2*01 F, TRGC2*02 F, TRGC2S1*01 P, TRGC3*01 F, TRGC4*01 P, TRGC5*01 F.

27 September 2021 - Update of Macaca mulatta (Rhesus monkey) TRA/TRD reference directory:
- Addition of 15 TRAJ alleles (15 F): TRAJ2*02 F, TRAJ12*02 F, TRAJ15*02 F, TRAJ19*02 F, TRAJ20*02 F, TRAJ22*02 F, TRAJ26*02 F, TRAJ32*02 F, TRAJ34*02 F, TRAJ35*02 F, TRAJ42*02 F, TRAJ44*02 F, TRAJ45*02 F, TRAJ49*02 F, TRAJ60*02 F.
- Addition of 1 TRDJ allele (1 F): TRDJ3*02 F.

24 September 2021 - Creation of the Heterocephalus glaber (Naked mole-rat) TRB reference directory: :
- Addition of 33 TRBV genes and 38 alleles (12 F, 7 ORF, 19 P): TRBV1S1*01 P, TRBV1S1*02 P, TRBV2*01 ORF, TRBV4*01 F, TRBV5*01 P, TRBV6*01 ORF, TRBV7*01 F, TRBV8*01 ORF, TRBV9*01 F, TRBV10*01 ORF, TRBV12-1*01 F, TRBV12-2*01 ORF, TRBV13*01 P, TRBV15*01 P, TRBV15*02 P, TRBV16*01 P, TRBV18-1*01 F, TRBV18-2*01 P, TRBV19-1*01 ORF, TRBV19-2*01 P, TRBV20-1*01 F, TRBV20-1*02 F, TRBV20-2*01 F, TRBV21*01 P, TRBV22*01 P, TRBV23-1*01 ORF, TRBV23-2*01 F, TRBV23-2*02 F, TRBV24-1*01 P, TRBV24-2*01, TRBV24-2*02, TRBV25*01 P, TRBV26*01 F, TRBV27*01 P, TRBV28*01 P, TRBV29*01 P, TRBV30*01 F, TRBVA*01 P.
- Addition of 2 TRBD genes and alleles ( 2 F): TRBD1*01 and TRBD2*01.
- Addition of 12 TRBJ genes and alleles (8 F, 4 ORF): TRBJ1-1*01 ORF, TRBJ1-2*01 F, TRBJ1-3*01 F, TRBJ1-5*01 ORF, TRBJ1-6*01 F, TRBJ2-1*01 ORF, TRBJ2-2*01 F, TRBJ2-3*01 F, TRBJ2-4*01 F, TRBJ2-5*01 F, TRBJ2-6*01 F, TRBJ2-7*01 ORF.
- Addition of 3 TRBC genes and alleles (3 F): TRBC1*01, TRBC2*01 and TRBC2*02.
20 September 2021 - Update of the Homo sapiens (human) IGKV and IGLV reference directory:
- Addition of 5 IGKV and 4 IGLV new alleles (9 F): IGKV1-8*02 F, IGKV1-8*03 F, IGKV1-5*04 F, IGKV1-5*05 F, IGKV4-1*02 F, IGLV1-44*02 F, IGLV1-44*03 F, IGLV2-14*05 F, IGLV7-46*04 F
- Update of the IMGT/LIGM-DB reference sequences of Homo sapiens (human) IGLV6-57*04 and IGLV10-54*04.

30 August 2021 - Update of Mus musculus (house mouse) IGH reference directory:
- Addition of 1 IGHV allele (1 P): IGHV(III)-7*02 P.
- IMGT reference accession number of Mus musculus (house mouse) IGHV(III)-5*02 and IGHV(III)-6*02 genes and alleles is IMGT000065 in IMGT/LIGM-DB.
27 July 2021 - Update of the Macaca mulatta (Rhesus monkey) IGH reference directory:
- Update of the Macaca mulatta (Rhesus monkey) IGHV gene and allele functionalities: Functionality of IGHV7-193*02 is F.
- Update of the Macaca mulatta (Rhesus monkey) IGHD gene and allele functionalities: -Functionality of IGHD1-26*01 is F -Functionality of IGHD1-38*01 is F -Functionality of IGHD4-11*01 is F -Functionality of IGHD4-17*01 is F
- Update of the Macaca mulatta (Rhesus monkey) IGHJ gene and allele functionalities: Functionality of IGHJ2*01 is F.
05 July 2021 - Creation of the Macaca fascicularis (Crab-eating macaque) TRB reference directory: :
- Addition of 78 TRBV genes and alleles (55 F, 4 ORF, 19 P ): TRBV1-1*01 P, TRBV1-2*01 P, TRBV1-3*01 P, TRBV10-1*01 F, TRBV10-2*01 F, TRBV10-3*01 F, TRBV11-1*01 F, TRBV11-2*01 F, TRBV11-3*01 F, TRBV12-1*01 ORF, TRBV12-2*01 F, TRBV12-3*01 F, TRBV12-4*01 F, TRBV13*01 F, TRBV14*01 F, TRBV15*01 F, TRBV16*01 F, TRBV17*01 P, TRBV18*01 F, TRBV19*01 F, TRBV2-1*01 F, TRBV2-2*01 F, TRBV2-3*01 F, TRBV20-1*01 F, TRBV21-1*01 F, TRBV22-1*01 P, TRBV23-1*01 F, TRBV24-1*01 F, TRBV25-1*01 F, TRBV26*01 P, TRBV27*01 F, TRBV28*01 F, TRBV29-1*01 F, TRBV3-1*01 F, TRBV3-2*01 F, TRBV3-3*01 F, TRBV3-4*01 F, TRBV30*01 F, TRBV4-1*01 F, TRBV4-2*01 F, TRBV4-3*01 F, TRBV5-1*01 P, TRBV5-10*01 F, TRBV5-2*01 P, TRBV5-3*01 F, TRBV5-4*01 F, TRBV5-5*01 P, TRBV5-6*01 P, TRBV5-7*01 F, TRBV5-8*01 F, TRBV5-9*01 F, TRBV6-1*01 F, TRBV6-2*01 F, TRBV6-2-1*01 ORF, TRBV6-3*01 F, TRBV6-4*01 P, TRBV6-5*01 ORF, TRBV6-5-1*01 P, TRBV6-6*01 F, TRBV6-7*01 P, TRBV6-8*01 ORF, TRBV7-1*01 P, TRBV7-10*01 F, TRBV7-2*01 F, TRBV7-3*01 F, TRBV7-4*01 F, TRBV7-5*01 F, TRBV7-6*01 F, TRBV7-7*01 F, TRBV7-7-1*01 F, TRBV7-8*01 P, TRBV7-9*01 F, TRBV8-1*01 P, TRBV8-2*01 P, TRBV9*01 F, TRBVA*01 P, TRBVB*01 P, TRBVC*01 P.
- Addition of 2 TRBD genes and alleles ( 2 F): TRBD1*01 and TRBD2*01.
- Addition of 14 TRBJ genes and alleles (13 F, 1 ORF): TRBJ1-1*01 F, TRBJ1-2*01 F, TRBJ1-3*01 F, TRBJ1-4*01 F, TRBJ1-5*01 F, TRBJ1-6*01 F, TRBJ2-1*01 F, TRBJ2-2*01 F, TRBJ2-2P*01 ORF, TRBJ2-3*01 F, TRBJ2-4*01 F, TRBJ2-5*01 F, TRBJ2-6*01 F, TRBJ2-7*01 F.
- Addition of 2 TRBC genes and alleles (2 F): TRBC1*01 and TRBC2*01.

01 July 2021 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of 3 IGHV (3 (P)): IGHV1-68D*02 (P), IGHV(III)-67-4D*02 (P), IGHV(III)-67-3D*02 (P)

20 May 2021 - Update of the Bos taurus (bovine) IGHC reference directory:
- Addition of 1 IGHD allele (1 F): IGHD*03 F.

17 May 2021 - Update of Mus musculus (house mouse) TRAV reference directory:
- Update of the assignment of the IMGT/LIGM-DB reference sequences of Mus musculus (house mouse) TRAV14-1*01 and TRAV14D-1*01:
  The assignment of L77149 and L77150 was revised. L77149 has been assigned to TRAV14-1*01 (instead of TRAV14D-1*01) and L77150 has been assigned to TRAV14D-1*01 (instead of TRAV14-1*01)
- Addition of 7 Mus musculus TRAV alleles: TRAV13-1*02 F, TRAV13D-1*04 F, TRAV13-2*03 F, TRAV13D-2*03 F, TRAV13-3*03 P, TRAV13-4/DV7*02 F and TRAV14-3*04 F.

27 April 2021 - Update of the Macaca mulatta (Rhesus monkey) TRBJ reference directory:
- Addition of 1 TRBJ allele (1 F): TRBJ1-6*03 F.

23 April 2021 - Update of the Macaca mulatta (Rhesus monkey) TRBV reference directory:
- Addition of 1 TRBV allele (1 F): TRBV9*03 F.

20 April 2021 - Update of Macaca fascicularis (crab-eating macaque) IGH reference directory:
- Functionality of IGHV3S14 is P.

20 April 2021 - Update of the Macaca mulatta (Rhesus monkey) IGKV reference directory:
- Addition of 1 IGKV allele (1 F): IGKV6-47*02 F.

08 April 2021 - Update of the Mus musculus (house mouse) IGK reference directory:
- IGKV(III)-25-1*01 is renamed IGKV3-25-1*01.

02 April 2021 - Update of Mus musculus (house mouse) IGK reference directory:
- Functionality of IGKV2-116*01 is F, IGKV4-73*01 is ORF, IGKV12-47*01 is ORF.
- Addition in IMGT/GENE-DB of:
- IMGT reference accession number of Mus musculus (house mouse) IGKV2-116*01 and IGKV6-13*01 genes and alleles is IMGT000068 in IMGT/LIGM-DB.

01 April 2021 - Update of Equus caballus (Horse) IGH reference directory:
- Functionality of IGHD2-29 is F.

31 March 2021 - Update of Macaca mulatta (Rhesus monkey) TRA/TRD reference directory:
- Addition of 1 TRDV gene and 3 alleles (3 F): TRDV1-1*01 F, TRDV1*02 F, TRDV2*02 F.
- Addition of 1 TRDC allele (1 F): TRDC*03 F.
- Addition of 5 TRAV genes and 26 alleles (21 F, 1 ORF, 4 P): TRAV22-3*01 F, TRAV23-4*01 F, TRAV24-1*01 F, TRAV25-1*01 F, TRAV26-3*01 F, TRAV1-1*02 F, TRAV12-1*02 F, TRAV13-1*02 F, TRAV13-2*02 F, TRAV15*02 F, TRAV19*02 F, TRAV20*02 F, TRAV22-1*02 F, TRAV23-1*02 F, TRAV25*02 F, TRAV26-2*02 F, TRAV8-6*02 P, TRAV32*02 P, TRAV33*02 P, TRAV34*02 F, TRAV35*02 F, TRAV36*02 F, TRAV37*02 ORF, TRAV38-1*02 F, TRAV38-2*02 F, TRAV40*02 F.
- Addition of 1 TRAC allele (1 F): TRAC*02 F.

29 March 2021 - Update of Mus musculus (house mouse) IGK reference directory:
- Functionality of IGKV2-116*01 is F, IGKV4-73*01 is ORF, IGKV12-47*01 is ORF.
- Addition in IMGT/GENE-DB of:
- IMGT reference accession number of Mus musculus (house mouse) IGKV2-116*01 and IGKV6-13*01 genes and alleles is IMGT000068 in IMGT/LIGM-DB.

24 March 2021 - Update of Macaca mulatta (Rhesus monkey) IGKV and IGHV reference directory:
- Addition of 1 IGKV gene and allele (1 P): IGKV2-14*01 P.
- Update of the Macaca mulatta (Rhesus monkey) IGHV in IMGT/GENE-DB reference directory sets in "F+ORF+in-frame P with IMGT gaps" FASTA sequences (Nucleotides, Amino acids).:
  - Position 15A added in the Macaca mulatta IGH V-REGION to take into account the additional glycine in the AB turn of FR1-IMGT of IGHV3-176*01 (Ed. M.-P. Lefranc).
  - Position 26A added in the Macaca mulatta IGH V-REGION to take into account the additional amino acid between the FR1-IMGT and the CDR1-IMGT of the P in-frame IGHV3-162 genes and alleles (Ed. M.-P. Lefranc).

12 March 2021 - Update of the Homo sapiens (human) IGKV and IGLV reference directory:
- Addition of 1 IGKV and 2 IGLV new alleles (3 (F)): IGKV1D-8*04 (F), IGLV10-54*04 (F), IGLV6-57*04 (F)

11 March 2021 - Update of the Macaca mulatta (Rhesus monkey) TRBJ reference directory:
- Functionality of TRBJ2-2P*01 and TRBJ2-2P*02 is ORF.

05 March 2021 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of 9 IGHV new alleles (4 F, 5 P): IGHV2-70*20 F, IGHV3-33*08 F, IGHV3-35*02 F, IGHV2-26*04 F, IGHV1-68*03 P, IGHV(III)-67-4*02 P, IGHV(II)-28-1*04 P, IGHV(II)-33-1*02 P, IGHV(III)-38-1*03 P

01 March 2021 - Update of Mus musculus (house mouse) IGH reference directory:
- Functionality of IGHV6-4*01 is ORF.
18 February 2021 - Update of the Equus caballus (horse) IGH reference directory:
- The Equus caballus (horse) IGHD reference directory includes 44 IGHD genes and 46 alleles (16 F, 30 ORF): IGHD1-32*01 ORF, IGHD1-42*01 ORF, IGHD2-12*01 F, IGHD2-15*01 F, IGHD2-18*01 F, IGHD2-21*01 ORF, IGHD2-23*01 F, IGHD2-26*01 F, IGHD2-29*01 ORF, IGHD2-3*01 ORF, IGHD2-36*01 F, IGHD2-39*01 ORF, IGHD2-6*01 F, IGHD2-9*01 F, IGHD3-1*01 ORF, IGHD3-10*01 ORF, IGHD3-10*02 ORF, IGHD3-13*01 ORF, IGHD3-16*01 ORF, IGHD3-19*01 ORF, IGHD3-22*01 ORF, IGHD3-24*01 ORF, IGHD3-24*02 ORF, IGHD3-27*01 ORF, IGHD3-30*01 ORF, IGHD3-37*01 ORF, IGHD3-4*01 ORF, IGHD3-40*01 ORF, IGHD3-7*01 ORF, IGHD4-11*01 F, IGHD4-14*01 ORF, IGHD4-17*01 ORF, IGHD4-2*01 F, IGHD4-20*01 ORF, IGHD4-25*01 ORF, IGHD4-28*01 ORF, IGHD4-31*01 F, IGHD4-35*01 F, IGHD4-38*01 F, IGHD4-41*01 ORF, IGHD4-5*01 F, IGHD4-8*01 ORF, IGHD6-34*01 F, IGHD6-44*01 F, IGHD7-33*01 ORF, IGHD7-43*01 ORF.
  See Gene table: horse (Equus caballus) IGHD
- Update of the Equus caballus (horse) IGHJ reference directory:
  - IGHJ6 is renamed IGHJ6-1.
  - IGHJ7 is renamed IGHJ6-2.
  - IGHJ8 is renamed IGHJ6-3.
  - IGHJ9 is renamed IGHJ6-4.
16 February 2021 - Update of Macaca mulatta (Rhesus monkey) IGL reference directory (following the annotation of IGL locus on chromosome 10 (CM014345.1 (29621424-30922134, complement)), assembly Mmul_10, GenBank assembly ID: GCA_003339765.3):
- The Macaca mulatta (Rhesus monkey) IGLV reference directory includes 149 genes and 225 alleles (109 F, 5 ORF, 111 P (15.96)): IGLV(IV)-127*01 P, IGLV(IV)-127*02 P, IGLV(V)-126*01 P, IGLV8-125*01 F, IGLV8-125*02 F, IGLV(I)-124*01 P, IGLV1-123*01 P, IGLV1-123*02 P, IGLV1-122*01 P, IGLV1-122*02 P, IGLV1-122*03 P, IGLV1-122*04 P, IGLV(IV)-121*01 P, IGLV5-120*01 P, IGLV5-120*02 P, IGLV5-120*03 P, IGLV5-119*01 P, IGLV5-119*02 P, IGLV(I)-118*01 P, IGLV(I)-118*02 P, IGLV11-117*01 F, IGLV(III)-116*01 P, IGLV(III)-116*02 P, IGLV(IV)-115*01 P, IGLV10-114*01 F, IGLV(IV)-113*01 P, IGLV(IV)-113*02 P, IGLV6-112*01 F, IGLV6-112*02 F, IGLV(IV)-111*01 P, IGLV(IV)-111*02 P, IGLV6-110*01 F, IGLV6-110*02 F, IGLV6-110*03 F, IGLV1-109*01 P, IGLV1-109*02 P, IGLV10-108*01 P, IGLV(I)-107*01 P, IGLV(I)-107*02 P, IGLV5-106*01 P, IGLV5-106*02 P, IGLV4-105*01 P, IGLV4-105*02 P, IGLV5-104*01 P, IGLV5-104*02 P, IGLV5-103*01 F, IGLV(III)-102*01 P, IGLV1-101*01 P, IGLV1-101*02 P, IGLV1-100*01 P, IGLV1-100*02 P, IGLV5-99*01 F, IGLV7-98*01 P, IGLV4-97*01 F, IGLV4-97*02 F, IGLV4-97*03 F, IGLV6-96*01 P, IGLV5-95*01 F, IGLV6-94*01 P, IGLV5-93*01 P, IGLV6-92*01 F, IGLV(I)-91*01 P, IGLV5-90*01 P, IGLV(I)-89*01 P, IGLV7-88*01 F, IGLV5-87*01 F, IGLV5-87*02 F, IGLV1-86*01 F, IGLV1-86*02 F, IGLV1-85*01 F, IGLV9-84*01 F, IGLV5-83*01 F, IGLV5-83*02 F, IGLV(I)-82*01 P, IGLV1-81*01 F, IGLV7-80*01 F, IGLV5-79*01 P, IGLV5-79*02 P, IGLV(I)-78*01 P, IGLV(I)-78*02 P, IGLV1-77*01 F, IGLV1-77*02 F, IGLV7-76*01 F, IGLV7-76*02 F, IGLV(I)-75*01 P, IGLV5-74*01 F, IGLV5-74*02 F, IGLV(I)-73*01 P, IGLV1-72*01 F, IGLV1-72*02 F, IGLV7-71*01 F, IGLV(I)-70*01 P, IGLV(I)-70*02 P, IGLV5-69*01 F, IGLV(I)-68*01 P, IGLV1-67*01 F, IGLV1-67*02 F, IGLV1-66*01 F, IGLV1-65*01 F, IGLV1-64*01 F, IGLV1-64*02 F, IGLV(I)-63*01 P, IGLV5-62*01 F, IGLV5-62*02 F, IGLV(I)-61*01 P, IGLV1-60*01 F, IGLV7-59*01 P, IGLV(I)-58*01 P, IGLV5-57*01 P, IGLV5-57*02 P, IGLV7-56*01 P, IGLV7-55*01 P, IGLV(III)-54*01 P, IGLV7-53*01 P, IGLV(I)-52*01 P, IGLV(I)-52*02 P, IGLV2-51*01 P, IGLV(II)-50*01 P, IGLV(II)-50*02 P, IGLV2-49*01 P, IGLV3-48*01 F, IGLV3-47*01 P, IGLV2-46*01 F, IGLV3-45*01 P, IGLV3-44*01 F, IGLV3-43*01 F, IGLV2-42*01 P, IGLV3-41*01 P, IGLV3-40*01 F, IGLV3-39*01 F, IGLV2-38*01 F, IGLV3-37*01 P, IGLV3-36*01 F, IGLV3-36*02 F, IGLV3-35*01 P, IGLV3-34*01 F, IGLV3-33*01 F, IGLV3-33*02 F, IGLV3-33*03 F, IGLV3-33*04 F, IGLV3-33*05 F, IGLV3-33*06 F, IGLV3-33*07 F, IGLV3-33*08 F, IGLV2-32*01 F, IGLV2-32*02 F, IGLV(I)-31*01 P, IGLV3-30*01 F, IGLV3-29*01 F, IGLV(I)-28*01 P, IGLV3-27*01 F, IGLV3-27*02 F, IGLV2-26*01 F, IGLV2-26*02 F, IGLV3-25*01 F, IGLV3-25*02 F, IGLV(I)-24*01 P, IGLV(I)-24*02 P, IGLV2-23*01 F, IGLV2-23*02 F, IGLV2-23*03 F, IGLV3-22*01 F, IGLV(II)-21*01 P, IGLV(II)-21*02 P, IGLV3-20*01 P, IGLV3-20*02 P, IGLV2-19*01 F, IGLV2-19*02 F, IGLV2-19*03 F, IGLV3-18*01 ORF, IGLV3-18*02 ORF, IGLV3-18*03 ORF, IGLV4-17*01 ORF, IGLV4-17*02 ORF, IGLV3-16*01 P, IGLV3-16*02 F, IGLV3-15*01 P, IGLV3-15*02 P, IGLV3-14*01 F, IGLV2-13*01 F, IGLV2-13*02 F, IGLV2-13*03 F, IGLV3-12*01 P, IGLV2-11*01 F, IGLV2-11*02 F, IGLV2-11*03 F, IGLV(II)-10*01 P, IGLV(II)-10*02 P, IGLV4-9*01 F, IGLV3-8*01 P, IGLV3-8*02 P, IGLV2-7*01 P, IGLV2-7*02 P, IGLV3-6*01 P, IGLV3-6*02 P, GLV(II)-5*01 P, IGLV3-4*01 P, IGLV3-4*02 P, IGLV3-3*01 P, IGLV3-3*02 P, IGLV3-2*01 F, IGLV3-1*01 P, IGLV3-1*02 P, IGLV1S1*01 F, IGLV1S2*01 F, IGLV1S4*01 F, IGLV1S6*01 F, IGLV2S4*01 F, IGLV2S7*01 F, IGLV2S8*01 P, IGLV2S9*01 F, IGLV3S10*01 F, IGLV3S11*01 F, IGLV3S12*01 F, IGLV3S13*01 F, IGLV3S14*01 F, IGLV3S15*01 F, IGLV3S16*01 F, IGLV3S17*01 P, IGLV3S19*01 P, IGLV3S20*01 P, IGLV3S3*01 F, IGLV3S7*01 F, IGLV3S9*01 F, IGLV4S1*01 F.
  See Gene table: Rhesus monkey (Macaca mulatta) IGLV
- Update of the Macaca mulatta (Rhesus monkey) IGLJ reference directory: addition of 2 IGLJ genes and 3 alleles (2 F, 1 ORF): IGLJ2A*01 F, IGLJ7*01 F, IGLJ7*02 ORF.
- Update of the Macaca mulatta (Rhesus monkey) IGLC reference directory: addition of 1 IGLC gene and 3 allele (1 F): IGLC2A*01 F.
15 February 2021 - Update of Macaca mulatta (Rhesus monkey) IGK reference directory (following the annotation of IGK locus on chromosome 13 (CM014348.1 (16784193-18140859)), assembly Mmul_10, GenBank assembly ID: GCA_003339765.3):
- The Macaca mulatta (Rhesus monkey) IGKV reference directory includes 137 genes and 205 alleles (128 F, 7 ORF, 70 P (35.35)): IGKV2-105*01 P, IGKV2-104*01 F, IGKV2-104*02 F, IGKV2-103*01 P, IGKV3-102*01 P, IGKV1-101*01 F, IGKV2-100*01 P, IGKV2-99*01 F, IGKV1-98*01 P, IGKV1-97*01 P, IGKV3-96*01 P, IGKV1-95*01 P, IGKV1-94*01 F, IGKV3-93*01 P, IGKV2-92*01 P, IGKV2-91*01 F, IGKV2-90*01 F, IGKV2-89*01 P, IGKV3-88*01 P, IGKV2-87*01 ORF, IGKV2-86*01 F, IGKV2-86*02 ORF, IGKV2-85*01 P, IGKV1-84*01 F, IGKV2-83*01 P, IGKV2-82*01 F, IGKV2-82*02 F, IGKV2-82*03 F, IGKV2-81*01 ORF, IGKV1-80*01 F, IGKV3-79*01 P, IGKV2-78*01 F, IGKV1-77*01 P, IGKV2-76*01 F, IGKV2-75*01 P, IGKV1-74*01 F, IGKV2-73*01 F, IGKV2-72*01 F, IGKV2-72*02 F, IGKV2-72*03 F, IGKV1-71*01 P, IGKV2-70*01 F, IGKV1-69*01 F, IGKV1-69*02 F, IGKV2-68*01 F, IGKV6-67*01 P, IGKV1-66*01 F, IGKV2-65*01 F, IGKV1-63D*01 P, IGKV2-64*01 F, IGKV2-64*02 F, IGKV1-63*01 P, IGKV1-63*02 P, IGKV2-62*01 P, IGKV2-62*02 F, IGKV2-61*01 F, IGKV2-61*02 P, IGKV2-61*03 F, IGKV2-60*01 F, IGKV2-60*02 F, IGKV1-59*01 F, IGKV1-59*02 F, IGKV2-58*01 F, IGKV2-58*02 P, IGKV2-58*03 F, IGKV2-57*01 P, IGKV2-57*02 P, IGKV1-56*01 P, IGKV1-56*02 P, IGKV6-55*01 F, IGKV1-54*01 P, IGKV3-53*01 F, IGKV3-53*02 F, IGKV1-52*01 ORF, IGKV2-51*01 P, IGKV2-51*02 P, IGKV1-50*01 P, IGKV2-49*01 P, IGKV2-49*02 P, IGKV2-48*01 P, IGKV2-48*02 P, IGKV6-47*01 F, IGKV1-46*01 F, IGKV1-46*02 P, IGKV6-45*01 P, IGKV1-44*01 F, IGKV1-44*02 F, IGKV1-44*03 F, IGKV1-43*01 F, IGKV1-43*02 F, IGKV1-43*03 F, IGKV3-42*01 F, IGKV3-42*02 F, IGKV3-42*03 F, IGKV1-41*01 F, IGKV1-41*02 F, IGKV3-40*01 F, IGKV3-40*02 F, IGKV3-40*03 F, IGKV2-39*01 P, IGKV1-38*01 F, IGKV1-38*02 F, IGKV1-37*01 F, IGKV1-37*02 P, IGKV1-36*01 F, IGKV1-36*02 F, IGKV1-36*03 F, IGKV3-35*01 F, IGKV3-35*02 F, IGKV3-35*03 F, IGKV2-34*01 P, IGKV1-33*01 F, IGKV1-33*02 F, IGKV1-32*01 F, IGKV1-32*02 F, IGKV1-32*03 F, IGKV1-32*04 F, IGKV1-32*05 F, IGKV3-31*01 F, IGKV3-31*02 F, IGKV2-30*01 P, IGKV2-30*02 P, IGKV1-29*01 P, IGKV1-29*02 P, IGKV1-28*01 F, IGKV1-28*02 F, IGKV1-28*03 F, IGKV1-27*01 F, IGKV3-26-1*01 ORF, IGKV2-26*01 P, IGKV2-26*02 P, IGKV1-25-1*01 P, IGKV1-25*01 F, IGKV1-25*02 F, IGKV1-25*03 P, IGKV3-24*01 F, IGKV3-24*02 F, IGKV3-24*03 F, IGKV3-24*04 F, IGKV2-23*01 P, IGKV2-23*02 P, IGKV1-22*01 F, IGKV1-21*01 F, IGKV1-20*01 P, IGKV1-19*01 F, IGKV1-18*01 F, IGKV3-17*01 F, IGKV3-17*02 F, IGKV3-17*03 F, IGKV1-16*01 F, IGKV3-15*01 P, IGKV2-13-2*01 P, IGKV2-13-1*01 F, IGKV7-13*01 P, IGKV7-13*02 F, IGKV3-12*01 P, IGKV3-12*02 P, IGKV5-11*01 F, IGKV5-11*02 F, IGKV3-10*01 F, IGKV3-10*02 F, IGKV(II)-9*01 P, IGKV(II)-9*02 P, IGKV4-8*01 P, IGKV4-8*02 P, IGKV2-7*01 P, IGKV2-7*02 F, IGKV1-6*01 F, IGKV5-5*01 F, IGKV(II)-4*01 P, IGKV(II)-4*02 P, IGKV4-3*01 P, IGKV4-3*02 P, IGKV2-2*01 P, IGKV2-2*02 P, IGKV4-1*01 F, IGKV4-1*02 F, IGKV1S11*01 F, IGKV1S12*01 F, IGKV1S13*01 F, IGKV1S14*01 F, IGKV1S15*01 F, IGKV1S16*01 F, IGKV1S17*01 F, IGKV1S19*01 F, IGKV1S21*01 F, IGKV1S25*01 F, IGKV1S3*01 F, IGKV1S4*01 F, IGKV1S5*01 F, IGKV1S6*01 F, IGKV1S8*01 F, IGKV1S9*01 F, IGKV2S15*01 F, IGKV2S16*01 ORF, IGKV2S2*01 F, IGKV2S20*01 F, IGKV2S3*01 F, IGKV2S6*01 P, IGKV2S8*01 F, IGKV2S9*01 F, IGKV3S11*01 F, IGKV3S5*01 F, IGKV3S9*01 F, IGKV4S1*01 ORF.
  See Gene table: Rhesus monkey (Macaca mulatta) IGKV
- Update of Macaca mulatta (Rhesus monkey) IGKC reference directory: addition of 1 IGKC allele (1 F): IGKC*02 F.
12 February 2021 - Update of Macaca mulatta (Rhesus monkey) IGH reference directory (following the annotation of IGH locus on chromosome 7 (CM014342.1 (167900000-169868564, complement)), assembly Mmul_10, GenBank assembly ID: GCA_003339765.3):
- The Macaca mulatta (Rhesus monkey) IGHV reference directory includes 228 genes and 336 alleles (122 F, 4 ORF, 210 P (32.178)): IGHV(II)-202*01 P, IGHV3-201*01 F, IGHV1-200*01 F, IGHV(III)-199*01 P, IGHV(III)-199*02 P, IGHV1-198*01 F, IGHV1-198*02 F, IGHV1-197*01 P, IGHV1-197*02 P, IGHV(III)-196*01 P, IGHV3-195*01 P, IGHV3-195*02 P, IGHV(III)-194*01 P, IGHV7-193*01 F, IGHV7-193*02 ORF, IGHV4-192*01 P, IGHV4-192*02 P, IGHV3-191*01 P, IGHV3-191*02 P, IGHV(II)-190*01 P, IGHV(II)-190*02 P, IGHV5-189*01 P, IGHV5-189*02 P, IGHV(III)-188*01 P, IGHV3-187*01 P, IGHV3-187*02 P, IGHV3-186*01 F, IGHV3-186*02 F, IGHV(II)-185*01 P, IGHV3-184*01 F, IGHV3-184*02 F, IGHV3-183*01 F, IGHV3-183*02 F, IGHV3-182*01 P, IGHV3-182*02 P, IGHV(III)-181*01 P, IGHV(III)-181*02 P, IGHV1-180*01 F, IGHV(III)-179*01 P, IGHV(III)-179*02 P, IGHV3-178*01 F, IGHV3-178*02 F, IGHV(II)-177*01 P, IGHV(II)-177*02 P, IGHV3-176*01 F, IGHV3-176*02 F, IGHV3-175*01 F, IGHV3-175*02 F, IGHV2-174*01 F, IGHV2-174*02 F, IGHV4-173*01 F, IGHV(I)-172*01 P, IGHV(I)-172*02 P, IGHV(III)-171*01 P, IGHV3-170*01 P, IGHV4-169*01 F, IGHV4-169*02 F, IGHV3-168*01 P, IGHV(II)-167*01 P, IGHV(II)-167*02 P, IGHV7-166*01 P, IGHV7-166*02 P, IGHV4-165*01 F, IGHV4-165*02 F, IGHV(I)-164*01 P, IGHV(I)-164*02 P, IGHV(III)-163*01 P, IGHV(III)-163*02 P, IGHV3-162*01 P, IGHV3-162*02 P, IGHV3-157D*01 P, IGHV1-156D*01 F, IGHV(III)-155D*01 P, IGHV(II)-154D*01 P, IGHV3-153D*01 F, IGHV2-161*01 F, IGHV4-160*01 F, IGHV(I)-159*01 P, IGHV(III)-158*01 P, IGHV3-157*01 P, IGHV1-156*01 F, IGHV(III)-155*01 P, IGHV(II)-154*01 P, IGHV(II)-154*02 P, IGHV3-153*01 F, IGHV3-153*02 F, IGHV2-152*01 F, IGHV1-151*01 F, IGHV1-150*01 P, IGHV7-149*01 P, IGHV3-148*01 P, IGHV4-147*01 F, IGHV3-146*01 P, IGHV(II)-145*01 P, IGHV7-144*01 P, IGHV4-143*01 F, IGHV(I)-142*01 P, IGHV(III)-141*01 P, IGHV(III)-140*01 P, IGHV3-139*01 P, IGHV1-138*01 F, IGHV3-137*01 P, IGHV3-136*01 F, IGHV(II)-135*01 P, IGHV3-134*01 F, IGHV(III)-133*01 P, IGHV(III)-133*02 P, IGHV3-132*01 F, IGHV3-132*02 F, IGHV(II)-131*01 P, IGHV(II)-131*02 P, IGHV1-130*01 P, IGHV1-130*02 P, IGHV(III)-129*01 P, IGHV(III)-129*02 P, IGHV7-128*01 P, IGHV7-128*02 P, IGHV4-127*01 F, IGHV1-126*01 P, IGHV(III)-125*01 P, IGHV(III)-125*02 P, IGHV3-124*01 F, IGHV(II)-123*01 P, IGHV4-122*01 F, IGHV4-122*02 F, IGHV1-121*01 P, IGHV1-121*02 P, IGHV(III)-120*01 P, IGHV3-119*01 F, IGHV3-119*02 P, IGHV3-118*01 F, IGHV3-117*01 P, IGHV3-116*01 F, IGHV3-116*02 F, IGHV3-115*01 F, IGHV3-115*02 F, IGHV7-114*01 F, IGHV1-113*01 P, IGHV1-113*02 P, IGHV(III)-112*01 P, IGHV(III)-112*02 P, IGHV1-111*01 F, IGHV1-111*02 F, IGHV3-110*01 F, IGHV3-110*02 F, IGHV(II)-109*01 P, IGHV3-108*01 F, IGHV7-107*01 P, IGHV4-106*01 F, IGHV4-106*02 P, IGHV3-105*01 P, IGHV3-105*02 P, IGHV(II)-104*01 P, IGHV3-103*01 F, IGHV3-103*02 F, IGHV3-102*01 P, IGHV(II)-101*01 P, IGHV(II)-101*02 P, IGHV3-100*01 F, IGHV3-100*02 F, IGHV4-99*01 F, IGHV4-99*02 F, IGHV(I)-98*01 P, IGHV(III)-97*01 P, IGHV(III)-96*01 P, IGHV2-95*01 F, IGHV7-94*01 P, IGHV4-93*01 F, IGHV4-93*02 F, IGHV4-92*01 F, IGHV4-92*02 P, IGHV1-91*01 P, IGHV1-90*01 P, IGHV1-89*01 P, IGHV(III)-88*01 P, IGHV(III)-88*02 P, IGHV7-87*01 P, IGHV4-86*01 P, IGHV1-85*01 P, IGHV(III)-84*01 P, IGHV(III)-84*02 P, IGHV(II)-83*01 P, IGHV7-82*01 P, IGHV4-81*01 F, IGHV4-80*01 F, IGHV(II)-79*01 P, IGHV3-78*01 F, IGHV7-77*01 P, IGHV4-76*01 F, IGHV1-75*01 P, IGHV(III)-74*01 P, IGHV4-73*01 F, IGHV3-72*01 F, IGHV(II)-71*01 P, IGHV1-70*01 F, IGHV1-69*01 F, IGHV(II)-68*01 P, IGHV3-67*01 P, IGHV7-66*01 P, IGHV4-65*01 F, IGHV4-65*02 F, IGHV(I)-64*01 P, IGHV(I)-64*02 P, IGHV(III)-63*01 P, IGHV(III)-63*02 P, IGHV3-62*01 P, IGHV3-62*02 P, IGHV(III)-61*01 P, IGHV(III)-61*02 P, IGHV(III)-60*01 P, IGHV(III)-60*02 P, IGHV3-59*01 F, IGHV3-59*02 F, IGHV3-58*01 F, IGHV3-58*02 F, IGHV4-57*01 P, IGHV4-57*02 F, IGHV3-56*01 P, IGHV3-56*02 P, IGHV(II)-55*01 P, IGHV(II)-55*02 P, IGHV3-54*01 F, IGHV3-54*02 F, IGHV3-53*01 P, IGHV3-53*02 P, IGHV(II)-52*01 P, IGHV(II)-52*02 P, IGHV(III)-51*01 P, IGHV(III)-51*02 P, IGHV3-50*01 P, IGHV3-50*02 P, IGHV3-49*01 P, IGHV3-49*02 P, IGHV3-48*01 P, IGHV3-48*02 P, IGHV(II)-47*01 P, IGHV(II)-47*02 P, IGHV3-46*01 P, IGHV3-46*02 F, IGHV(II)-45*01 P, IGHV(II)-45*02 P, IGHV8-44*01 P, IGHV8-44*02 P, IGHV5-43*01 F, IGHV5-43*02 F, IGHV(III)-42*01 P, IGHV(III)-42*02 P, IGHV3-41*01 P, IGHV3-41*02 P, IGHV3-40*01 P, IGHV3-40*02 P, IGHV3-39*01 P, IGHV3-39*02 P, IGHV3-38*01 F, IGHV3-38*02 F, IGHV3-37*01 F, IGHV3-37*02 F, IGHV(II)-36*01 P, IGHV(II)-36*02 P, IGHV3-35*01 F, IGHV3-35*02 F, IGHV3-34*01 F, IGHV3-34*02 F, IGHV(II)-33*01 P, IGHV3-32*01 F, IGHV3-32*02 F, IGHV(II)-31*01 P, IGHV(II)-31*02 P, IGHV3-30*01 F, IGHV3-30*02 F, IGHV(II)-29*01 P, IGHV(II)-29*02 P, IGHV3-28*01 F, IGHV3-28*02 F, IGHV3-27*01 P, IGHV3-27*02 P, IGHV(II)-26*01 P, IGHV(II)-26*02 P, IGHV(III)-25*01 P, IGHV3-24*01 P, IGHV3-24*02 P, IGHV3-23*01 P, IGHV3-23*02 P, IGHV(II)-22*01 P, IGHV(II)-22*02 P, IGHV8-21*01 P, IGHV8-21*02 P, IGHV5-20*01 F, IGHV5-20*02 F, IGHV(III)-19*01 P, IGHV(III)-19*02 P, IGHV3-18*01 ORF, IGHV3-18*02 ORF, IGHV(II)-17*01 P, IGHV(II)-17*02 P, IGHV3-16*01 F, IGHV3-16*02 F, IGHV(II)-15*01 P, IGHV(II)-15*02 P, IGHV3-14*01 P, IGHV3-13*01 F, IGHV3-12*01 F, IGHV3-12*02 F, IGHV(III)-11*01 P, IGHV2-10*01 ORF, IGHV(II)-9*01 P, IGHV3-8*01 F, IGHV3-7*01 P, IGHV(II)-6*01 P, IGHV3-5*01 P, IGHV(II)-4*01 P, IGHV4-3*01 P, IGHV(II)-2*01 P, IGHV(II)-2*02 P, IGHV6-1*01 F, IGHV(II)-33D*01 P, IGHV(III)S4*01 P, IGHV1S12*01 P, IGHV1S2*01 F, IGHV1S3*01 P, IGHV1S9*01 P, IGHV2S1*01 F, IGHV2S2*01 P, IGHV3S18*01 P, IGHV3S3*01 P, IGHV3S4*01 F, IGHV3S40*01 F, IGHV3S41*01 F, IGHV3S42*01 F, IGHV3S43*01 F, IGHV4S10*01 F, IGHV4S13*01 F, IGHV4S2*01 F, IGHV4S9*01 F, IGHV7S6*01 P, IGHV7S8*01 P.
  See Gene table: Rhesus monkey (Macaca mulatta) IGHV
- The Macaca mulatta (Rhesus monkey) IGHD reference directory includes 45 IGHD genes and 49 alleles (44 F and 5 ORF): IGHD1-1*01 F, IGHD1-1-1*01 F, IGHD1-14*01 F, IGHD1-20*01 F, IGHD1-26*01 ORF, IGHD1-32*01 F, IGHD1-38*01 ORF, IGHD1-44*01 F, IGHD1-44*02 F, IGHD1-7*01 F, IGHD1-7*02 F, IGHD2-15*01 F, IGHD2-2*01 F, IGHD2-21*01 F, IGHD2-27*01 F, IGHD2-33*01 F, IGHD2-39*01 F, IGHD2-39*02 F, IGHD2-8*01 F, IGHD3-16*01 F, IGHD3-22*01 F, IGHD3-28*01 F, IGHD3-3*01 F, IGHD3-34*01 F, IGHD3-40*01 F, IGHD3-9*01 F, IGHD4-11*01 ORF, IGHD4-17*01 ORF, IGHD4-23*01 F, IGHD4-29*01 F, IGHD4-35*01 F, IGHD4-4*01 F, IGHD4-41*01 F, IGHD5-12*01 F, IGHD5-18*01 ORF, IGHD5-24*01 F, IGHD5-30*01 F, IGHD5-36*01 F, IGHD5-36*02 F, IGHD5-42*01 F, IGHD5-5*01 F, IGHD6-13*01 F, IGHD6-19*01 F, IGHD6-25*01 F, IGHD6-31*01 F, IGHD6-37*01 F, IGHD6-43*01 F, IGHD6-6*01 F, IGHD7-45*01 F.
  See Gene table: Rhesus monkey (Macaca mulatta) IGHD
- Update of the Macaca mulatta (Rhesus monkey) IGHJ reference directory: addition of 2 IGHJ genes and alleles (2 F): IGHJ1*02 F, IGHJ5-1*02 F.
  See Gene table: Rhesus monkey (Macaca mulatta) IGHJ
- Update of the Macaca mulatta (Rhesus monkey) IGHC reference directory: addition of 1 IGHC gene and 9 IGHC alleles (8 F and 1 ORF): IGHM*03 F, IGHD*03, IGHG1*03 F, IGHG2*07 ORF, IGHG2*08 F, IGHG3*07 F, IGHG4*05 F, IGHE*01 F, IGHA*22 F.
- Update of the Macaca mulatta (Rhesus monkey) IGHC gene and allele functionalities:
  Functionality of IGHD*01 is F.
  Functionality of IGHG3*07 is P.
  
  See Gene table: Rhesus monkey (Macaca mulatta) IGHC
02 February 2021 - Update of the Macaca mulatta (Rhesus monkey) TRB reference directory:
- Addition of 48 TRBV new alleles (36 F, 2 ORF, 10 P): TRBV1-1*02 P, TRBV1-3*02 P, TRBV2-1*02 F, TRBV2-3*02 F, TRBV3-2*02 F, TRBV3-3*02 F, TRBV3-4*02 F, TRBV4-1*02 F, TRBV4-2*02 F, TRBV4-3*03 F, TRBV5-1*03 P, TRBV5-3*03 F, TRBV5-4*03 F, TRBV5-5*03 F, TRBV5-6*02 F, TRBV5-7*02 P, TRBV5-8*02 F, TRBV5-9*03 F, TRBV5-10*02 F, TRBV6-2*03 F, TRBV6-2-1*02 P, TRBV6-4*03 P, TRBV6-6*02 F, TRBV6-8*02 F, TRBV7-2*03 F, TRBV7-4*03 F, TRBV7-5*02 F, TRBV7-6*02 F, TRBV7-7*02 ORF, TRBV7-7-1*02 F, TRBV7-9*02 F, TRBV7-10*02 F, TRBV8-2*02 P, TRBV11-2*02 F, TRBV12-1*02 ORF, TRBV12-2*03 F, TRBV12-3*02 F, TRBV12-4*02 F, TRBV13*02 F, TRBV16*02 F, TRBV19*02 F, TRBV20-1*02 F, TRBV21-1*02 F, TRBV22-1*02 P, TRBV26*02 P, TRBV27*02 F, TRBV29-1*02 F, TRBVC*02 P. (IMGT000073 is reference sequence)
- Addition of 1 TRBJ new allele (1 F): TRBJ1-1*02 F. (IMGT000073 is reference sequence)
- Addition of 2 TRBC new alleles (2 F): TRBC1*02 F, TRBC2*03 F. (IMGT000073 is reference sequence)
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) TRBV in IMGT/GENE-DB reference directory sets: Update of gap position 85A in "F+ORF+in-frame P with IMGT gaps" FASTA sequences (Nucleotides, Amino acids).
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) TRBV5-3*01 and TRBV5-3*02. Update of gap position 82.
- Functionality of TRBV5-3*02 is F.
- Functionality of TRBV6-2-1*01 is ORF.
- TRBV7-2*02 was deleted. TRBV7-2*01 reference sequence is IMGT000012 and sequence of the literature is NW_001114291.
28 January 2021 - Update of the Equus caballus (horse) IGHV reference directory:
- Addition of 2 IGHV genes and 3 alleles ( 2 F, 1 P): IGHV1-70*03 F, IGHV4-38N*01 P, IGHV4-37N*01 F.
  - IGHV1S1*01 is renamed IGHV1-70*02.
  - IGHV1S2*01 is renamed IGHV1-84*01.
  - IGHV4-37D*02 is renamed IGHV4-37*02.
27 January 2021 - Update of the Equus caballus (horse) IGHV reference directory:
- Addition of 2 IGHV genes and alleles (2 P): IGHV3-40N*01 P, IGHV3-39N*01 P.
15 January 2021 - Update of the Homo sapiens (human) IGHV/OR16 orphon set reference directory:
- Addition of IGHV orphons on chromosome 16 (3 P): IGHV1/OR16-26*01 P, IGHV(III)/OR16-27*01 P and IGHV(III)/OR16-28*01 P. (IMGT000069 is reference sequence)
07 January 2021 - Update of Mus musculus (house mouse) IGH reference directory:
- Functionality of IGHV1-14*01 is P.
- Addition in IMGT/GENE-DB of:
- IMGT reference accession number of Mus musculus (house mouse) IGHG1*02 and IGHG2C*03 genes and alleles is IMGT000065 in IMGT/LIGM-DB.
17 November 2020 - Update of the Homo sapiens (human) IGHV/OR16 orphon set reference directory:
- Addition of IGHV orphons on chromosome 16 (3 P): IGHV2/OR16-23*01 P, IGHV1/OR16-24*01 P and IGHV(III)/OR16-25*01 P. (IMGT000069 is reference sequence)
29 October 2020 - Update of the Homo sapiens (human) IGHV/OR16 orphon set reference directory:
- Addition of IGHV orphons on chromosome 16 (2 ORF, 4 P): IGHV3/OR16-17*01 ORF, IGHV3/OR16-18*01 P, IGHV3/OR16-19*01 P, IGHV3/OR16-20*01 ORF, IGHV1/OR16-21*01 P, IGHV1/OR16-22*01 P.
- IMGT000069 is reference sequence for: IGHV1/OR16-1*01 P, IGHV1/OR16-2*01 P, IGHV1/OR16-3*01 P, IGHV1/OR16-4*01 P, IGHV3/OR16-7*01 P, IGHV3/OR16-8*01 ORF, IGHV3/OR16-9*01 ORF, IGHV3/OR16-10*01 ORF, IGHV3/OR16-11*01 P, IGHV3/OR16-12*01 ORF, IGHV3/OR16-13*01 ORF, IGHV3/OR16-16*01 P, IGHV3/OR16-17*01 ORF, IGHV3/OR16-18*01 P, IGHV3/OR16-19*01 P, IGHV3/OR16-20*01 ORF, IGHV1/OR16-21*01 P, IGHV1/OR16-22*01 P.
15 October 2020 - Update of the Homo sapiens (human) TRAV reference directory:
- Update of 1 Homo sapiens TRAV reference sequences in IMGT reference sequences: TRAV33*01 P (IMGT000024)
- Addition in IMGT/GENE-DB of:
1 October 2020 - Update of the Homo sapiens (human) IGLV reference directory:
- Update of 7 Homo sapiens IGLV reference sequences in IMGT reference sequences: IGLV4-60*03 F, IGLV2-14*03 F (IMGT-NC_Report_2020-1-0917_Homsap_IGLV), IGLV3-29*01, IGLV2-28*01, IGLV3-26*01, IGLV3-12*01, IGLV2-11*01.
- Addition in IMGT/GENE-DB of:
29 September 2020
- Update of Bos taurus (bovine) TRA reference directory: TRAV2-1*01 functionnality is F.
22 September 2020
- Update of the IMGT numbering for Felis catus (domestic cat) TRAC*01.
- Update of the IMGT numbering for Felis catus (domestic cat) TRDC*01.
- Update of the IMGT numbering for Canis lupus familiaris (dog) TRDC*01.
- Update of the IMGT numbering for Homo sapiens (human) TRDC*01.
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) TRDC*01.
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) TRDC*02.
- Update of the IMGT numbering for Mus musculus (mouse) TRDC*01.
- Update of the IMGT numbering for Oryctolagus cuniculus (rabbit) TRDC*01.
- Update of the IMGT numbering for Tursiops truncatus (Bottlenose dolphin) TRDC*01.
- Update of the Canis lupus familiaris (Dog) TRA/TRD gene and allele nomenclature:
- Update of the IMGT numbering for Canis lupus familiaris (Dog) TRAV33
- Addition of 1 Canis lupus familiaris (Dog) TRDV gene and allele : TRDV2*01 P.
- Update of the Felis catus (Cat) TRA/TRD gene and allele nomenclature:
  
  TRDV gene and allele old name TRDV gene and allelle new name
  
  TRDV2-2*01 TRDV2*01
  
  TRDV gene and allele old name TRAV gene and allelle new name
  
  TRDV2-1*01 TRAV33*01
- Update of the IMGT numbering for Felis catus (Cat) TRAV33
15 September 2020 - Update of the Macaca mulatta (Rhesus monkey) IGH reference directory:
- Addition of 1 IGHC genes and alleles (1 F): IGHA*22 F.
14 September 2020 - Update of the Macaca mulatta (Rhesus monkey) IGH reference directory:
- Addition of 1 IGHC gene and allele (1 F): IGHD*03 F.
14 September 2020 - Update of the Equus caballus (horse) IGHD gene and allele functionalities:
Functionality of IGHD4*01 is ORF.
Functionality of IGHD7*01 is ORF.
Functionality of IGHD16*01 is ORF.
Functionality of IGHD23*01 is F.
Functionality of IGHD25*01 is F.
Functionality of IGHD27*01 is F.
Functionality of IGHD28*01 is F.
Functionality of IGHD29*01 is ORF.
Functionality of IGHD34*01 is ORF.
Functionality of IGHD35*01 is ORF.
Functionality of IGHD37*01 is ORF.
Functionality of IGHD38*01 is ORF.
Functionality of IGHD39*01 is ORF.
Update of the Equus caballus (horse) IGHJ reference directory:
- Update of IGHJ1*01 and IGHJ2*01 reference sequence (removal of the last nt in 3').
- Functionality of IGHJ1*01 is ORF.
Update of the Equus caballus (horse) IGHV reference directory:
Functionality of IGHV2-77*01 is ORF.

TRDV gene and allele old name	TRAV gene and allelle new name
TRDV2*01	TRAV33*01

TRDV gene and allele old name	TRDV gene and allelle new name
TRDV2-2*01	TRDV2*01

TRDV gene and allele old name	TRAV gene and allelle new name
TRDV2-1*01	TRAV33*01

4 September 2020 - Update of the Macaca mulatta (Rhesus monkey) IGH reference directory

Update of the Macaca mulatta (Rhesus monkey) IGHV gene and allele nomenclature following the annotation of IMGT000064:

IGHV gene and allele old name	IGHV gene and allele new name
IGHV4-4*01	IGHV4-1-2*01
IGHV(II)-12*01	IGHV(II)-2*01
IGHV3-24*01	IGHV3-3*01
IGHV(II)-11*01	IGHV(II)-4*01
IGHV3-23*01	IGHV3-5*01
IGHV3-22*01	IGHV3-6*01
IGHV4-3*01	IGHV(II)-6-1*01
IGHV2-2*01	IGHV2-7*01
IGHV3-21*01	IGHV3-8*02
IGHV3-20*01	IGHV3-9*01
IGHV3-19*01	IGHV3-10*01
IGHV(II)-10*01	IGHV(II)-11*02
IGHV3-18*01	IGHV3-12*02
IGHV(II)-9*01	IGHV(II)-13*02
IGHV3-17*01	IGHV3-14*02
IGHV5-2*01	IGHV5-16*02
IGHV(III)-4*01	IGHV8-17*02
IGHV(II)-8*01	IGHV(II)-18*02
IGHV3-16*01	IGHV3-19*02
IGHV(II)-7*01	IGHV(II)-22*02
IGHV3-15*01	IGHV3-23*02
IGHV3-14*01	IGHV3-24*02
IGHV(II)-6*01	IGHV(II)-25*02
IGHV3-13*01	IGHV3-26*02
IGHV3-12*01	IGHV3-144*02
IGHV(II)-5*01	IGHV(II)-145*02
IGHV(II)-4*01	IGHV(III)-146*01
IGHV1-2*01	IGHV(I)-162*02
IGHV4-2*01	IGHV4-163*01
IGHV2-1*01	IGHV2-164*02
IGHV3-11*01	IGHV3-165*02
IGHV3-10*01	IGHV3-166*02
IGHV(II)-3*01	IGHV(II)-167*02
IGHV3-9*01	IGHV3-168*02
IGHV(III)-3*01	IGHV(III)-169*02
IGHV1-1*01	IGHV1-170*01
IGHV(III)-2*01	IGHV(III)-171*02
IGHV3-8*01	IGHV3-172*02
IGHV3-7*01	IGHV3-173*02
IGHV3-6*01	IGHV3-174*02
IGHV(II)-2*01	IGHV(II)-175*01
IGHV3-5*01	IGHV3-176*02
IGHV3-4*01	IGHV3-177*02
IGHV(III)-1*01	IGHV(III)-178*01
IGHV5-1*01	IGHV5-179*02
IGHV(II)-1*01	IGHV(II)-180*02
IGHV3-3*01	IGHV3-181*02
IGHV4-1*01	IGHV4-182*02
IGHV7-1*01	IGHV7-183*02
IGHV3-2*01	IGHV(III)-184*01
IGHV3-1*01	IGHV3-185*02

IGHV6-1*01 reference sequence is IMGT000064.

Addition of 145 IGHV genes and 185 IGHV alleles (67 F, 2 ORF and 116 P): IGHV1-64*01 F, IGHV1-65*01 F, IGHV1-69*01 P, IGHV1-79*01 P, IGHV1-83*01 P, IGHV1-84*01 P, IGHV1-85*01 P, IGHV1-105*01 F, IGHV1-107*01 P, IGHV1-114*01 P, IGHV1-119*01 P, IGHV1-123*01 P, IGHV1-130*01 F, IGHV1-141*01 P, IGHV1-142*01 F, IGHV1-147*01 F, IGHV1-147D*01 F, IGHV1-187*01 P, IGHV1-188*01 F, IGHV1-190*01 F, IGHV2-89*01 F, IGHV2-143*01 F, IGHV2-151*01 F, IGHV2-164*01 F, IGHV3-8*01 F, IGHV3-12*01 F, IGHV3-14*01 ORF, IGHV3-19*01 P, IGHV3-20*01 P, IGHV3-20*02 P, IGHV3-23*01 P, IGHV3-24*01 F, IGHV3-26*01 F, IGHV3-28*01 F, IGHV3-30*01 F, IGHV3-31*01 F, IGHV3-33*01 F, IGHV3-34*01 F, IGHV3-35*01 P, IGHV3-36*01 P, IGHV3-37*01 P, IGHV3-42*01 P, IGHV3-44*01 P, IGHV3-45*01 P, IGHV3-46*01 P, IGHV3-48*01 P, IGHV3-49*01 F, IGHV3-51*01 P, IGHV3-53*01 F, IGHV3-54*01 F, IGHV3-57*01 P, IGHV3-62*01 P, IGHV3-66*01 F, IGHV3-72*01 F, IGHV3-94*01 F, IGHV3-96*01 P, IGHV3-97*01 F, IGHV3-99*01 P, IGHV3-102*01 F, IGHV3-104*01 F, IGHV3-109*01 F, IGHV3-110*01 F, IGHV3-111*01 P, IGHV3-112*01 F, IGHV3-113*01 F, IGHV3-117*01 F, IGHV3-124*01 F, IGHV3-126*01 F, IGHV3-128*01 F, IGHV3-129*01 P, IGHV3-131*01 P, IGHV3-137*01 P, IGHV3-139*01 P, IGHV3-144*01 F, IGHV3-144D*01 F, IGHV3-148*01 P, IGHV3-148D*01 P, IGHV3-152*01 P, IGHV3-158*01 P, IGHV3-160*01 P, IGHV3-165*01 F, IGHV3-166*01 F, IGHV3-168*01 F, IGHV3-172*01 P, IGHV3-173*01 F, IGHV3-174*01 F, IGHV3-176*01 ORF, IGHV3-177*01 P, IGHV3-181*01 P, IGHV3-185*01 P, IGHV3-191*01 F, IGHV4-52*01 P, IGHV4-60*01 F, IGHV4-67*01 F, IGHV4-70*01 F, IGHV4-74*01 F, IGHV4-75*01 F, IGHV4-80*01 P, IGHV4-86*01 F, IGHV4-87*01 F, IGHV4-93*01 F, IGHV4-100*01 F, IGHV4-115*01 F, IGHV4-120*01 F, IGHV4-135*01 F, IGHV4-138*01 F, IGHV4-150*01 F, IGHV4-155*01 F, IGHV4-159*01 F, IGHV4-182*01 P, IGHV5-16*01 F, IGHV5-39*01 F, IGHV5-179*01 P, IGHV7-61*01 P, IGHV7-71*01 P, IGHV7-76*01 P, IGHV7-81*01 P, IGHV7-88*01 P, IGHV7-101*01 P, IGHV7-108*01 F, IGHV7-121*01 P, IGHV7-136*01 P, IGHV7-140*01 P, IGHV7-156*01 P, IGHV7-183*01 F, IGHV8-17*01 P, IGHV8-40*01 P, IGHV(I)-59*01 P, IGHV(I)-92*01 P, IGHV(I)-134*01 P, IGHV(I)-149*01 P, IGHV(I)-154*01 P, IGHV(I)-162*01 P, IGHV(II)-1-1*01 P, IGHV(II)-6-1*01 P, IGHV(II)-11*01 P, IGHV(II)-13*01 P, IGHV(II)-18*01 P, IGHV(II)-22*01 P, IGHV(II)-25*01 P, IGHV(II)-27*01 P, IGHV(II)-29*01 P, IGHV(II)-32*01 P, IGHV(II)-41*01 P, IGHV(II)-43*01 P, IGHV(II)-50*01 P, IGHV(II)-63*01 P, IGHV(II)-73*01 P, IGHV(II)-77*01 P, IGHV(II)-95*01 P, IGHV(II)-98*01 P, IGHV(II)-103*01 P, IGHV(II)-116*01 P, IGHV(II)-127*01 P, IGHV(II)-145*01 P, IGHV(II)-145D*01 P, IGHV(II)-157*01 P, IGHV(II)-167*01 P, IGHV(II)-180*01 P, IGHV(III)-15*01 P, IGHV(III)-15*02 P, IGHV(III)-21*01 P, IGHV(III)-38*01 P, IGHV(III)-47*01 P, IGHV(III)-55*01 P, IGHV(III)-56*01 P, IGHV(III)-58*01 P, IGHV(III)-68*01 P, IGHV(III)-78*01 P, IGHV(III)-82*01 P, IGHV(III)-90*01 P, IGHV(III)-91*01 P, IGHV(III)-106*01 P, IGHV(III)-118*01 P, IGHV(III)-122*01 P, IGHV(III)-125*01 P, IGHV(III)-132*01 P, IGHV(III)-133*01 P, IGHV(III)-146D*01 P, IGHV(III)-153*01 P, IGHV(III)-161*01 P, IGHV(III)-169*01 P, IGHV(III)-171*01 P, IGHV(III)-186*01 P, IGHV(III)-189*01 P.

2 September 2020 - Update of the Macaca mulatta (Rhesus monkey) IGH reference directory:
- Addition of 1 IGHC genes and 5 alleles (5 F): IGHE*01 F, IGHG1*03 F, IGHG2*08 F, IGHG3*07, IGHG4*05 F.
13 August 2020 - Update of the Bos taurus (bovine) TRA/TRD reference directory:
- Update of the IMGT numbering for Bos taurus (bovine) TRAV38-5.
08 August 2020 - Update of the Ovis aries (sheep) TRA/TRD reference directory:
- Addition of 2 TRAV genes and alleles (P): TRAV14-4*01 P and TRAV21-1*01 P.

28 July 2020 - Update of the Equus caballus (horse) IGHV gene and allele nomenclature:

Update of the Equus caballus (horse) IGHV gene and allele nomenclature:

IGHV gene and allele old name	IGHV gene and allelle new name
IGHV4-23*01	IGHV4-22*01
IGHV4-24*01	IGHV4-23*01
IGHV3-25*01	IGHV3-24*01
IGHV4-26*01	IGHV4-25*01
IGHV3-27*01	IGHV3-26*01
IGHV3-28*01	IGHV3-27*01
IGHV4-30*01	IGHV4-28*01
IGHV4-31*01	IGHV4-29*01
IGHV4-32*01	IGHV4-30*01
IGHV1-33*01	IGHV1-31*01
IGHV3-34*01	IGHV3-32*01
IGHV4-35*01	IGHV4-33*01
IGHV7-36*01	IGHV7-34*01
IGHV4-37*01	IGHV4-35*01
IGHV7-36D*01	IGHV7-34D*01
IGHV3-38*01	IGHV3-36*01
IGHV4-39*01	IGHV4-37*01
IGHV4-40*01	IGHV4-38*01
IGHV3-41*01	IGHV3-39*01
IGHV3-42*01	IGHV3-40*01
IGHV1-43*01	IGHV1-41*01
IGHV4-39D*01	IGHV4-37D*01
IGHV4-40D*01	IGHV4-38D*01
IGHV3-41D*01	IGHV3-39D*01
IGHV3-42D*01	IGHV3-40D*01
IGHV1-43D*01	IGHV1-41D*01
IGHV4-49*01	IGHV4-42*01
IGHV(II)-50*01	IGHV(II)-43*01
IGHV3-51*01	IGHV3-44*01
IGHV(II)-50D*01	IGHV(II)-43D*01
IGHV4-49D*01	IGHV4-42D*01
IGHV1-54*01	IGHV1-45*01
IGHV3-55*01	IGHV3-46*01
IGHV3-56*01	IGHV3-47*01
IGHV4-49N*01	IGHV4-42N*01
IGHV(II)-50N*01	IGHV(II)-43N*01
IGHV4-59*01	IGHV4-48*01
IGHV4-60*01	IGHV4-49*01
IGHV3-61*01	IGHV3-50*01
IGHV4-62*01	IGHV4-51*01
IGHV4-63*01	IGHV4-52*01
IGHV4-64*01	IGHV4-53*01
IGHV(II)-65*01	IGHV(II)-54*01
IGHV4-66*01	IGHV4-55*01
IGHV3-67*01	IGHV3-56*01
IGHV4-68*01	IGHV4-57*01
IGHV3-69*01	IGHV3-58*01
IGHV4-70*01	IGHV4-59*01
IGHV3-71*01	IGHV3-60*01
IGHV1-72*01	IGHV1-61*01
IGHV3-73*01	IGHV3-62*01
IGHV2-74*01	IGHV2-63*01
IGHV3-75*01	IGHV3-64*01
IGHV4-76*01	IGHV4-65*01
IGHV9-77*01	IGHV9-66*01
IGHV5-78*01	IGHV5-67*01
IGHV4-79*01	IGHV4-68*01
IGHV3-80*01	IGHV3-69*01
IGHV1-81*01	IGHV1-70*01
IGHV5-82*01	IGHV5-71*01
IGHV4-83*01	IGHV4-72*01
IGHV3-84*01	IGHV3-73*01
IGHV4-85*01	IGHV4-74*01
IGHV4-86*01	IGHV4-75*01
IGHV3-87*01	IGHV3-76*01
IGHV4-37D*01	IGHV4-35D*01
IGHV5-36D*01	IGHV5-34D*01
IGHV4-35D*01	IGHV4-33D*01
IGHV2-91*01	IGHV2-77*01
IGHV3-92*01	IGHV3-78*01
IGHV1-93*01	IGHV1-79*01
IGHV3-94*01	IGHV3-80*01
IGHV4-95*01	IGHV4-81*01
IGHV4-96*01	IGHV4-82*01
IGHV1S4*01	IGHV1S2*01
IGHV1S2*01	IGHV1-41*01
IGHV1S3*01	IGHV3-26*01

22 July 2020 - Update of the Canis lupus familiaris (dog) IGK reference directory:

Update of the Canis lupus familiaris (dog) IGKV gene and allele nomenclature:

IGKV gene and allele old name	IGKV gene and allelle new name
IGKV2-4*01	IGKV2-4*02
IGKV2-5*01	IGKV2-5*02
IGKV2-11*01	IGKV2-11*02
IGKV2S12*01	IGKV2-21*02
IGKV2S14*01	IGKV2-20*02
IGKV2S15*01	IGKV2-19*01
IGKV2S16*01	IGKV2-16*01
IGKV2S18*01	IGKV2-13*02
IGKV2S19*01	IGKV2-12*02
IGKV3S1*01	IGKV3-18*02
IGKV4S1*01	IGKV4-15*01
IGKV(II)-1*01	IGKV(II)-14*01

IGKV2-6*01, IGKV2-7*01, IGKV2-8*01, IGKV2-9*01, IGKV2-10*01, IGKV2-16*01, IGKV2-19*01, IGKV3-3*01, IGKV4-1*01, IGKV4-15*01, IGKV7-2*01 and IGKV(II)-14*01 reference sequence is IMGT000067.
Addition of 5 IGKV genes and 14 alleles (4 F and 10 P): IGKV1-23*01 P, IGKV2-4*01 F, IGKV2-5*01 P, IGKV2-11*01 F, IGKV2-12*01 F, IGKV2-13*01 P, IGKV2-20*01 P, IGKV2-21*01 P, IGKV3-18*01 F, IGKV8-22*01 P, IGKV9-24*01 P, IGKV(II)-1-1*01 P, IGKV(II)-17*01 P and IGKV(II)-17*02 P.

IGKJ1*01, IGKJ2*01, IGKJ3*01, IGKJ4*01 and IGKJ5*01 reference sequence is IMGT000067.

Update of the Canis lupus familiaris (dog) IGKC gene and allele nomenclature:

IGKV gene and allele old name	IGKV gene and allelle new name
IGKC*01	IGKC*02

Addition of 1 IGKC allele (F): IGKC*01 F.

7 July 2020
- Update of the Equus caballus (horse) IGHD reference directory: functionality of IGHD26*01 is F.
06 July 2020 - Update of the Ovis aries (sheep) TRA/TRD reference directory:
- Addition of 1 TRAV gene and allele (ORF): TRAV14S1*01 ORF.
- Addition of 11 TRDV genes and 24 alleles (11 F and 13 ORF): TRDV1S8*01 F, TRDV1S1*03 F, TRDV1-46*02 ORF, TRDV1S9*01 F, TRDV1-43*03 F, TRDV1S10*01 F, TRDV1S11*01 F, TRDV1-8*02 F, TRDV1S12*01 F, TRDV1-17*02 ORF, TRDV1S13*01 ORF, TRDV1-54*02 ORF, TRDV1-5*03 F, TRDV1S14*01 F, TRDV1-53*02 ORF, TRDV1S15*01 ORF, TRDV1S16*01 ORF, TRDV1S17*01 ORF, TRDV1S18*01 ORF, TRDV3*02 F, TRDV1S9*02 ORF, TRDV1S10*02 ORF, TRDV1-8*03 ORF and TRDV1-54*03 ORF.

30 June 2020

Update of the Camelus dromedarius (Arabian camel) TRDV gene and allele nomenclature:

TRDV gene and allele old name	TRAV gene and allelle new name
TRDV2S1*01	TRAV33S1*01
TRDV2S2*01	TRAV33S2*01
TRDV2S3*01	TRAV33S3*01

Update of the Tursiops truncatus (Bottlenose dolphin) TRAJ gene and allele nomenclature:

TRAJ gene and allele old name	TRAJ gene and allelle new name
TRAJ29*01	TRAJ28*01
TRAJ30*01	TRAJ29*01
TRAJ31*01	TRAJ30*01
TRAJ32*01	TRAJ31*01
TRAJ33*01	TRAJ32*01
TRAJ34*01	TRAJ33*01
TRAJ35*01	TRAJ34*01
TRAJ36*01	TRAJ35*01
TRAJ37*01	TRAJ36*01
TRAJ38*01	TRAJ37*01
TRAJ39*01	TRAJ38*01
TRAJ40*01	TRAJ39*01
TRAJ41*01	TRAJ40*01
TRAJ42*01	TRAJ41*01
TRAJ43*01	TRAJ42*01
TRAJ44*01	TRAJ43*01
TRAJ45*01	TRAJ44*01
TRAJ46*01	TRAJ45*01
TRAJ47*01	TRAJ46*01
TRAJ48*01	TRAJ47*01
TRAJ49*01	TRAJ48*01
TRAJ50*01	TRAJ49*01
TRAJ51*01	TRAJ50*01

25 June 2020

Update of the Ovis aries (sheep) TRAJ gene and allele nomenclature:

TRAJ gene and allele old name	TRAJ gene and allelle new name
TRAJ8*01	TRAJ8-1*01
TRAJ10*01	TRAJ8-2*01
TRAJ11*01	TRAJ10*01
TRAJ11*02	TRAJ10*02
TRAJ12*01	TRAJ11*01
TRAJ13*01	TRAJ12*01
TRAJ14*01	TRAJ13*01
TRAJ15*01	TRAJ14*01
TRAJ16*01	TRAJ15*01
TRAJ17*01	TRAJ16*01
TRAJ18*01	TRAJ17*01
TRAJ19*01	TRAJ18*01
TRAJ20*01	TRAJ19*01
TRAJ21*01	TRAJ20*01
TRAJ22*01	TRAJ21*01
TRAJ23*01	TRAJ22*01
TRAJ24*01	TRAJ23*01
TRAJ25*01	TRAJ24*01
TRAJ26*01	TRAJ25*01
TRAJ27*01	TRAJ26*01
TRAJ28*01	TRAJ27*01
TRAJ29*01	TRAJ28*01
TRAJ30*01	TRAJ29*01
TRAJ30D*01	TRAJ29D*01
TRAJ30N*01	TRAJ29N*01
TRAJ31*01	TRAJ30*01
TRAJ31D*01	TRAJ30D*01
TRAJ32*01	TRAJ31*01
TRAJ32D*01	TRAJ31D*01
TRAJ32N*01	TRAJ31N*01
TRAJ33*01	TRAJ32*01
TRAJ33*02	TRAJ32*02
TRAJ33D*01	TRAJ32D*01
TRAJ33N*01	TRAJ32N*01
TRAJ34*01	TRAJ33*01
TRAJ34D*01	TRAJ33D*01
TRAJ34N*01	TRAJ33N*01
TRAJ35*01	TRAJ34*01
TRAJ35D*01	TRAJ34D*01
TRAJ35N*01	TRAJ34N*01
TRAJ36*01	TRAJ35*01
TRAJ36*02	TRAJ35*02
TRAJ36D*01	TRAJ35D*01
TRAJ36N *01	TRAJ35N*01
TRAJ37*01	TRAJ36*01
TRAJ37D*01	TRAJ36D*01
TRAJ37N*01	TRAJ36N*01
TRAJ38*01	TRAJ37*01
TRAJ38*02	TRAJ37*02
TRAJ38D*01	TRAJ37D*01
TRAJ38N*01	TRAJ37N*01
TRAJ39*01	TRAJ38*01
TRAJ39D*01	TRAJ38D*01
TRAJ40*01	TRAJ39*01
TRAJ40D*01	TRAJ39D*01
TRAJ41*01	TRAJ40*01
TRAJ42*01	TRAJ41*01
TRAJ43*01	TRAJ42*01
TRAJ44*01	TRAJ43*01
TRAJ45*01	TRAJ44*01
TRAJ45D*01	TRAJ44D*01
TRAJ46*01	TRAJ45*01
TRAJ47*01	TRAJ46*01
TRAJ48*01	TRAJ47*01
TRAJ49*01	TRAJ48*01
TRAJ50*01	TRAJ49*01
TRAJ51*01	TRAJ50*01
TRAJ55*01	TRAJ56*01
TRAJ56*01	TRAJ57*01
TRAJ57*01	TRAJ58*01
TRAJ58*01	TRAJ59*01
TRAJ59*01	TRAJ60*01
TRAJ60*01	TRAJ61*01

Update of the Bos taurus (bovine) TRAJ gene and allele nomenclature:

TRAJ gene and allele old name	TRAJ gene and allelle new name
TRAJ8*01	TRAJ8-1*01
TRAJ10*01	TRAJ8-2*01
TRAJ10*02	TRAJ8-2*02
TRAJ11*01	TRAJ10*01
TRAJ12*01	TRAJ11*01
TRAJ12*02	TRAJ11*02
TRAJ13*01	TRAJ12*01
TRAJ14*01	TRAJ13*01
TRAJ14*02	TRAJ13*02
TRAJ15*01	TRAJ14*01
TRAJ15*02	TRAJ14*02
TRAJ16*01	TRAJ15*01
TRAJ16*02	TRAJ15*02
TRAJ17*01	TRAJ16*01
TRAJ18*01	TRAJ17*01
TRAJ19*01	TRAJ18*01
TRAJ20*01	TRAJ19*01
TRAJ21*01	TRAJ20*01
TRAJ22*01	TRAJ21*01
TRAJ23*01	TRAJ22*01
TRAJ24*01	TRAJ23*01
TRAJ25*01	TRAJ24*01
TRAJ26*01	TRAJ25*01
TRAJ26*02	TRAJ25*02
TRAJ27*01	TRAJ26*01
TRAJ28*01	TRAJ27*01
TRAJ29*01	TRAJ28*01
TRAJ30*01	TRAJ29*01
TRAJ31*01	TRAJ30*01
TRAJ32*01	TRAJ31*01
TRAJ32*02	TRAJ31*02
TRAJ33*01	TRAJ32*01
TRAJ34*01	TRAJ33*01
TRAJ35*01	TRAJ34*01
TRAJ36*01	TRAJ35*01
TRAJ37*01	TRAJ36*01
TRAJ38*01	TRAJ37*01
TRAJ38*02	TRAJ37*02
TRAJ39*01	TRAJ38*01
TRAJ40*01	TRAJ39*01
TRAJ40*02	TRAJ39*02
TRAJ41*01	TRAJ40*01
TRAJ42*01	TRAJ41*01
TRAJ42*02	TRAJ41*02
TRAJ43*01	TRAJ42*01
TRAJ44*01	TRAJ43*01
TRAJ45*01	TRAJ44*01
TRAJ46*01	TRAJ45*01
TRAJ46*02	TRAJ45*02
TRAJ47*01	TRAJ46*01
TRAJ48*01	TRAJ47*01
TRAJ49*01	TRAJ48*01
TRAJ50*01	TRAJ49*01
TRAJ51*01	TRAJ50*01
TRAJ55*01	TRAJ56*01
TRAJ56*01	TRAJ57*01
TRAJ57*01	TRAJ58*01
TRAJ58*01	TRAJ59*01
TRAJ59*01	TRAJ60*01
TRAJ60*01	TRAJ61*01

19 June 2020 - Update of the Camelus dromedarius (Arabian camel) IGKV gene nomenclature:

IGKV gene old name IGKV gene new name

IGKV(II)-6*01 IGKV(I)-6*01
19 June 2020 - Update of the Equus caballus (Horse) IGK reference directory:
- IMGT reference accession number of Equus caballus (Horse) IGKV4-1*02 genes and alleles is X75611 in IMGT/LIGM-DB.
- IMGT reference accession number of Equus caballus (Horse) IGKJ2*02 genes and alleles is X75613 in IMGT/LIGM-DB.

16 June 2020 - Update of the Ovis aries (sheep) TRA/TRD reference directory:

Update of the Ovis aries (sheep) TRAV gene and allele nomenclature and functionalities:

TRAV gene and allele old name	Old functionality	TRAV gene and allelle new name	New functionality
TRAV2-1*01		TRAV2*02
TRAV3-1*01		TRAV3*02
TRAV3S4*01		TRAV8-24*02
TRAV4-1*01		TRAV4-1*02
TRAV5-1*01		TRAV5*02
TRAV6-1*01		TRAV6*02
TRAV8-1*01		TRAV8-6*02
TRAV9S1*01		TRAV9-3*02
TRAV9S2*01		TRAV9-1*02
TRAV9S3*01		TRAV9S1*01
TRAV9S4*01		TRAV9-6*01
TRAV9S5*01		TRAV9-7*02
TRAV10-1*01		TRAV10-2*02
TRAV11S1*01		TRAV11-2*02
TRAV12-1*01		TRAV12-6*02
TRAV13-1*01		TRAV13S1*01
TRAV13S2*01		TRAV13-13*01
TRAV14S1*01	ORF	TRAV14-10*01	F
TRAV14S2*01		TRAV14-11*01
TRAV16S1*01		TRAV16*02
TRAV17-1*01		TRAV17-2*02
TRAV21-1*01		TRAV21-3*02
TRAV22S1*01		TRAV22-13*02
TRAV22S2*01		TRAV22-26*01
TRAV22S3*01		TRAV22-6*02
TRAV22S4*01		TRAV22-1*01
TRAV22S5*01	ORF	TRAV22-11*02	F
TRAV22S6*01		TRAV22S1*01
TRAV22S7*01		TRAV22-29*02
TRAV23S1*01		TRAV23-27*02
TRAV23S2*01		TRAV23S1*01
TRAV23S4*01		TRAV23-36*02
TRAV23S5*01	P	TRAV23-11*01	F
TRAV23S6*01		TRAV23-31*01
TRAV23S7*01		TRAV23-28*02
TRAV23S8*01		TRAV23-18*02
TRAV24S1*01		TRAV24-2*01
TRAV25S1*01		TRAV25-19*02
TRAV25S2*01		TRAV25-26*02
TRAV26S1*01		TRAV26-1*01
TRAV26S2*01		TRAV26-2*02
TRAV27-1*01		TRAV27*02
TRAV28S1*01		TRAV28-1*02
TRAV28S2*01		TRAV28-2*02
TRAV29S1*01		TRAV29-1*02
TRAV29S2*01		TRAV29-2*01
TRAV34-1*01		TRAV34*01
TRAV35-1*01		TRAV35*02
TRAV36-1*01		TRAV36*02
TRAV37-1*01	F	TRAV37*01	P
TRAV38-1*01		TRAV38-1*02
TRAV39-1*01	F	TRAV39*02	ORF
TRAV41-1*01		TRAV41*02
TRAV42S1*01		TRAV8-1*02
TRAV42S2*01		TRAV8-22*02
TRAV42S3*01		TRAV8S1*01
TRAV42S4*01		TRAV8-8*02
TRAV42S5*01		TRAV8-20*02
TRAV43S1*01		TRAV43-1*02
TRAV43S3*01		TRAV43-10*02
TRAV43S4*01		TRAV43S1*01
TRAV43S5*01		TRAV22-27*02
TRAV43S6*01		TRAV43-9*02
TRAV44S2*01		TRAV44-21*02
TRAV44S3*01		TRAV44-9*01
TRAV44S4*01		TRAV44-20*02
TRAV44S5*01		TRAV44S2*01
TRAV44S6*01		TRAV44S4*01
TRAV44S7*01		TRAV44S3*01
TRAV45S1*01	F	TRAV45-3*02	ORF
TRAV45S2*01		TRAV45S1*01
TRAV45S3*01		TRAV45S2*01
TRAV45S4*01		TRAV45S3*01
TRAV45S5*01		TRAV45S2*02

TRAV1*01, TRAV9-6*01, TRAV13-13*01, TRAV14-10*01, TRAV14-11*01, TRAV22-1*01, TRAV22-26*01, TRAV23-11*01, TRAV23-19*01, TRAV23-31*01, TRAV24-2*01, TRAV26-1*01, TRAV29-2*01, TRAV33-2*01, TRAV34*01, TRAV37*01 and TRAV44-9*01 reference sequence is IMGT000048.
Addition of 229 TRAV genes and 279 alleles (117 F, 10 ORF and 152 P): TRAV1*01 ORF, TRAV2*01 ORF, TRAV3*01 F, TRAV4-1*01 F, TRAV4-2*01 F, TRAV5*01 P, TRAV6*01 P, TRAV8-1*01 F, TRAV8-2*01 P, TRAV8-3*01 P, TRAV8-4*01 P, TRAV8-5*01 F, TRAV8-6*01 F, TRAV8-7*01 P, TRAV8-8*01 F, TRAV8-9*01 P, TRAV8-10*01 F, TRAV8-11*01 P, TRAV8-12*01 P, TRAV8-13*01 P, TRAV8-14*01 F, TRAV8-15*01 P, TRAV8-16*01 P, TRAV8-17*01 P, TRAV8-18*01 P, TRAV8-19*01 P, TRAV8-20*01 P, TRAV8-21*01 P, TRAV8-22*01 P, TRAV8-23*01 P, TRAV8-24*01 P, TRAV8-25*01 P, TRAV8-26*01 F, TRAV8-27*01 P, TRAV8-28*01 P, TRAV8-29*01 P, TRAV9-1*01 F, TRAV9-1D*01 F, TRAV9-1N*01 F, TRAV9-2*01 P, TRAV9-3*01 P, TRAV9-4*01 F, TRAV9-5*01 P, TRAV9-6*01 F, TRAV9-6D*01 F, TRAV9-7*01 P, TRAV9-8*01 P, TRAV10-1*01 P, TRAV10-2*01 F, TRAV11-1*01 P, TRAV11-2*01 P, TRAV11-2D*01 P, TRAV12-1*01 F, TRAV12-1D*01 F, TRAV12-2*01 F, TRAV12-3*01 P, TRAV12-4*01 F, TRAV12-5*01 P, TRAV12-6*01 F, TRAV13-1*01 F, TRAV13-2*01 F, TRAV13-2D*01 F, TRAV13-3*01 P, TRAV13-4*01 P, TRAV13-5*01 P, TRAV13-6*01 P, TRAV13-7*01 P, TRAV13-8*01 P, TRAV13-9*01 P, TRAV13-10*01 F, TRAV13-10D*01 F, TRAV13-11*01 P, TRAV13-12*01 F, TRAV13-12*01 F, TRAV13-13*01 F, TRAV13-14*01 F, TRAV13-15*01 P, TRAV13-16*01 P, TRAV13-17*01 F, TRAV13-18*01 F, TRAV14-1*01 P, TRAV14-2*01 F, TRAV14-2D*01 F, TRAV14-3*01 P, TRAV14-5*01 P, TRAV14-6*01 P, TRAV14-7*01 F, TRAV14-8*01 F, TRAV14-9*01 P, TRAV14-10*01 F, TRAV14-11*01 F, TRAV14-12*01 F, TRAV16*01 F, TRAV17-1*01 P, TRAV17-2*01 P, TRAV18-1*01 P, TRAV18-2*01 F, TRAV19*01 P, TRAV20-1*01 F, TRAV20-2*01 P, TRAV20-3*01 P, TRAV20-4*01 F, TRAV21-2*01 F, TRAV21-3*01 F, TRAV21-4*01 P, TRAV21-5*01 P, TRAV22-1*01 P, TRAV22-1D*01 P, TRAV22-2*01 P, TRAV22-3*01 F, TRAV22-4*01 P, TRAV22-5*01 F, TRAV22-6*01 F, TRAV22-7*01 F, TRAV22-8*01 P, TRAV22-9*01 F, TRAV22-10*01 F, TRAV22-11*01 F, TRAV22-12*01 P, TRAV22-13*01 F, TRAV22-14*01 P, TRAV22-15*01 P, TRAV22-16*01 F, TRAV22-17*01 P, TRAV22-18*01 P, TRAV22-19*01 F, TRAV22-20*01 F, TRAV22-21*01 F, TRAV22-22*01 F, TRAV22-23*01 P, TRAV22-24*01 P, TRAV22-25*01 P, TRAV22-26*01 F, TRAV22-27*01 P, TRAV22-28*01 F, TRAV22-29*01 P, TRAV22-30*01 P, TRAV22-31*01 F, TRAV22-32*01 P, TRAV22-33*01 F, TRAV22-34*01 P, TRAV22-35*01 P, TRAV22-36*01 P, TRAV22-37*01 F, TRAV22-38*01 P, TRAV22-39*01 F, TRAV22-40*01 F, TRAV22-41*01 P, TRAV23-1*01 F, TRAV23-2*01 P, TRAV23-3*01 F, TRAV23-4*01 P, TRAV23-5*01 P, TRAV23-6*01 F, TRAV23-7*01 P, TRAV23-8*01 F, TRAV23-9*01 P, TRAV23-10*01 P, TRAV23-11*01 F, TRAV23-12*01 P, TRAV23-13*01 P, TRAV23-14*01 P, TRAV23-15*01 P, TRAV23-15D*01 P, TRAV23-16*01 P, TRAV23-17*01 P, TRAV23-18*01 P, TRAV23-19*01 P, TRAV23-20*01 P, TRAV23-21*01 ORF, TRAV23-22*01 P, TRAV23-23*01 ORF, TRAV23-24*01 P, TRAV23-25*01 P, TRAV23-26*01 P, TRAV23-27*01 P, TRAV23-28*01 P, TRAV23-29*01 P, TRAV23-30*01 P, TRAV23-31*01 P, TRAV23-31*02 P, TRAV23-32*01 P, TRAV23-33*01 P, TRAV23-34*01 P, TRAV23-35*01 P, TRAV23-36*01 P, TRAV23-37*01 P, TRAV24-1*01 P, TRAV24-2*01 P, TRAV24-3*01 ORF, TRAV24-4*01 P, TRAV24-5*01 P, TRAV24-6*01 ORF, TRAV24-7*01 P, TRAV24-8*01 F, TRAV25-1*01 F, TRAV25-2*01 F, TRAV25-3*01 F, TRAV25-4*01 ORF, TRAV25-5*01 P, TRAV25-6*01 F, TRAV25-7*01 ORF, TRAV25-8*01 F, TRAV25-9*01 P, TRAV25-10*01 P, TRAV25-11*01 P, TRAV25-12*01 P, TRAV25-13*01 F, TRAV25-14*01 P, TRAV25-15*01 P, TRAV25-16*01 P, TRAV25-17*01 F, TRAV25-18*01 P, TRAV25-19*01 F, TRAV25-20*01 P, TRAV25-21*01 F, TRAV25-22*01 F, TRAV25-23*01 P, TRAV25-24*01 P, TRAV25-25*01 P, TRAV25-26*01 F, TRAV26-1*01 F, TRAV26-2*01 F, TRAV27*01 P, TRAV28-1*01 F, TRAV28-2*01 F, TRAV29-1*01 F, TRAV29-2*01 F, TRAV33-1*01 P, TRAV33-1*02 P, TRAV33-2*01 F, TRAV34*01 P, TRAV35*01 P, TRAV36*01 F, TRAV37*01 P, TRAV38-1*01 F, TRAV38-2*01 F, TRAV39*01 ORF, TRAV41*01 F, TRAV43-1*01 F, TRAV43-2*01 F, TRAV43-2D*01 F, TRAV43-3*01 F, TRAV43-4*01 F, TRAV43-4D*01 F, TRAV43-5*01 F, TRAV43-6*01 F, TRAV43-6D*01 F, TRAV43-7*01 P, TRAV43-8*01 F, TRAV43-9*01 P, TRAV43-10*01 F, TRAV43-11*01 F, TRAV44-1*01 P, TRAV44-2*01 F, TRAV44-3*01 F, TRAV44-4*01 F, TRAV44-5*01 P, TRAV44-6*01 F, TRAV44-7*01 ORF, TRAV44-8*01 F, TRAV44-9*01 F, TRAV44-10*01 P, TRAV44-11*01 F, TRAV44-12*01 P, TRAV44-13*01 P, TRAV44-14*01 P, TRAV44-15*01 P, TRAV44-16*01 F, TRAV44-17*01 P, TRAV44-18*01 F, TRAV44-19*01 P, TRAV44-20*01 P, TRAV44-21*01 F, TRAV45-1*01 P, TRAV45-2*01 F, TRAV45-3*01 P, TRAV46*01 P and TRAV46*02 P.

Update of the Ovis aries (sheep) TRAJ gene and allele nomenclature and functionalities:

TRAJ gene and allele old name	Old functionality	TRAJ gene and allelle new name	New functionality
TRAJ3*01	F	TRAJ3*02	ORF
TRAJ4*01	F		ORF
TRAJ5*01		TRAJ5*02
TRAJ9*01		TRAJ9*02
TRAJ11*01		TRAJ11*02
TRAJ13*01	F		ORF
TRAJ14*01	F		ORF
TRAJ20*01		TRAJ21*01
TRAJ21*01		TRAJ22*01
TRAJ22*01		TRAJ23*01
TRAJ23*01		TRAJ24*01
TRAJ24*01		TRAJ25*01
TRAJ25*01		TRAJ26*01
TRAJ26*01		TRAJ27*01
TRAJ27*01		TRAJ28*01
TRAJ28*01		TRAJ29*01
TRAJ29*01		TRAJ30*01
TRAJ30*01		TRAJ31*01
TRAJ31*01		TRAJ32*01
TRAJ32*01		TRAJ33*02
TRAJ33*01		TRAJ34*01
TRAJ34*01		TRAJ35*01
TRAJ35*01		TRAJ36*02
TRAJ36*01		TRAJ37*01
TRAJ37*01		TRAJ38*02
TRAJ38*01		TRAJ39*01
TRAJ39*01		TRAJ40*01
TRAJ40*01		TRAJ41*01
TRAJ41*01		TRAJ42*01
TRAJ42*01		TRAJ43*01
TRAJ43*01		TRAJ44*01
TRAJ44*01		TRAJ45*01
TRAJ45*01		TRAJ45D*01
TRAJ53*01		TRAJ52*01
TRAJ54*01		TRAJ53*01
TRAJ55*01		TRAJ54*01
TRAJ56*01		TRAJ55*01
TRAJ57*01		TRAJ56*01
TRAJ58*01		TRAJ57*01
TRAJ59*01		TRAJ58*01
TRAJ60*01		TRAJ59*01
TRAJ61*01		TRAJ60*01

TRAJ1*01, TRAJ2*01, TRAJ4*01, TRAJ6*01, TRAJ7*01, TRAJ8*01, TRAJ10*01, TRAJ12*01, TRAJ13*01, TRAJ14*01, TRAJ15*01, TRAJ16*01, TRAJ17*01, TRAJ18*01, TRAJ19*01, TRAJ21*01, TRAJ22*01, TRAJ23*01, TRAJ24*01, TRAJ25*01, TRAJ26*01, TRAJ27*01, TRAJ28*01, TRAJ29*01, TRAJ30*01, TRAJ31*01, TRAJ32*01, TRAJ34*01, TRAJ35*01, TRAJ37*01, TRAJ39*01, TRAJ40*01, TRAJ41*01, TRAJ42*01, TRAJ43*01, TRAJ44*01, TRAJ45*01, TRAJ46*01, TRAJ47*01, TRAJ48*01, TRAJ49*01, TRAJ50*01, TRAJ51*01, TRAJ52*01, TRAJ53*01, TRAJ54*01, TRAJ55*01, TRAJ56*01, TRAJ57*01, TRAJ58*01, TRAJ59*01 and TRAJ60*01 reference sequence is IMGT000048.
Addition of 20 TRAJ genes and 27 alleles (13 F, 2 ORF and 12 P): TRAJ3*01 ORF, TRAJ5*01 F, TRAJ9*01 F, TRAJ11*01 F, TRAJ20*01 P, TRAJ30D*01 ORF, TRAJ30N*01 F, TRAJ31D*01 P, TRAJ32D*01 P, TRAJ32N*01 P, TRAJ33*01 F, TRAJ33D*01 F, TRAJ33N*01 P, TRAJ34D*01 F, TRAJ34N*01 P, TRAJ35D*01 F, TRAJ35N*01 P, TRAJ36*01 F, TRAJ36D*01 F, TRAJ36N*01 P, TRAJ37D*01 F, TRAJ37N*01 P, TRAJ38*01 F, TRAJ38D*01 F, TRAJ38N*01 P, TRAJ39D*01 P and TRAJ40D*01 P.
Deletion of 1 TRAJ gene and allele (1 P): TRAJ52*01 P.

TRAC*01 reference sequence is IMGT000048.

Update of the Ovis aries (sheep) TRDV gene and allele nomenclature and functionalities:

TRDV gene and allele old name	Old functionality	TRDV gene and allelle new name	New functionality
TRDV1S1*01		TRDV1-5*02
TRDV1S2*01		TRDV1-22*01
TRDV1S3*01		TRDV1S1*01
TRDV1S4*01		TRDV1-33*02
TRDV1S5*01	F	TRDV1-34*02	P
TRDV1S6*01		TRDV1-42*01
TRDV1S7*01		TRDV1-43*02
TRDV1S8*01	F	TRDV1-44*01	ORF
TRDV1S9*01		TRDV1-45*01
TRDV1S10*01		TRDV1-48*01
TRDV1S11*01		TRDV1-62*02
TRDV1S12*01		TRDV1S1*02
TRDV1S13*01		TRDV1-18*02
TRDV1S14*01		TRDV1-9*02
TRDV1S15*01		TRDV1-26*02
TRDV1S16*01	F	TRDV1S2*01	ORF
TRDV1S17*01		TRDV1-2*02
TRDV1S18*01		TRDV1S3*01
TRDV1S19*01		TRDV1-63*02
TRDV1S20*01		TRDV1-40*02
TRDV1S21*01		TRDV1S6*01
TRDV1S22*01		TRDV1S5*01
TRDV1S23*01		TRDV1S4*01
TRDV1S24*01		TRDV1-25*02
TRDV1S25*01		TRDV1S7*01
TRDV1S26*01		TRDV1-12*02
TRDV2-1*01		TRAV33-2*01
TRDV2S2*01	F	TRDV2*02	ORF
TRDV2S3*01		TRAV33-1*02
TRDV3-1*01		TRDV5*02
TRDV4-1*01		TRDV3*01

TRDV1-22*01, TRDV1-42*01, TRDV1-44*01, TRDV1-45*01, TRDV1-48*01, TRDV3*01 and TRDV4*01 reference sequence is IMGT000048.
Addition of 48 TRDV genes and 63 alleles (28 F, 4 ORF and 31 P): TRDV1-1*01 P, TRDV1-2*01 F, TRDV1-2D*01 F, TRDV1-3*01 F, TRDV1-4*01 P, TRDV1-5*01 F, TRDV1-6*01 P, TRDV1-7*01 P, TRDV1-8*01 F, TRDV1-9*01 F, TRDV1-10*01 P, TRDV1-11*01 P, TRDV1-12*01 F, TRDV1-13*01 F, TRDV1-14*01 ORF, TRDV1-15*01 P, TRDV1-16*01 P, TRDV1-17*01 P, TRDV1-18*01 F, TRDV1-19*01 P, TRDV1-20*01 ORF, TRDV1-21*01 F, TRDV1-23*01 ORF, TRDV1-24*01 P, TRDV1-25*01 P, TRDV1-26*01 P, TRDV1-27*01 F, TRDV1-28*01 P, TRDV1-29*01 P, TRDV1-30*01 P, TRDV1-31*01 F, TRDV1-32*01 F, TRDV1-33*01 F, TRDV1-34*01 F, TRDV1-35*01 F, TRDV1-36*01 P, TRDV1-37*01 P, TRDV1-38*01 P, TRDV1-39*01 F, TRDV1-40*01 F, TRDV1-41*01 P, TRDV1-43*01 F, TRDV1-46*01 F, TRDV1-47*01 P, TRDV1-49*01 F, TRDV1-50*01 P, TRDV1-51*01 P, TRDV1-52*01 F, TRDV1-53*01 F, TRDV1-54*01 P, TRDV1-55*01 P, TRDV1-56*01 P, TRDV1-57*01 F, TRDV1-58*01 P, TRDV1-59*01 P, TRDV1-60*01 F, TRDV1-61*01 P, TRDV1-62*01 P, TRDV1-63*01 F, TRDV1-64*01 P, TRDV1-65*01 F, TRDV2*01 ORF and TRDV5*01 F.

Update of the Ovis aries (sheep) TRDD gene and allele nomenclature:

TRDD gene and allele old name	Old functionality	TRDD gene and allelle new name	New functionality
TRDD1*01		TRDD2*01
TRDD2*01		TRDD4*01
TRDD3*01	F	TRDD5*01	ORF
TRDD4*01		TRDD6*01
TRDD5*01	F	TRDD7*01	ORF
TRDD6*01		TRDD8*01
TRDD7*01		TRDD9*01

TRDD2*01, TRDD4*01, TRDD5*01, TRDD6*01, TRDD7*01, TRDD8*01 and TRDD9*01 reference sequence is IMGT000048.
Addition of 2 TRDD genes and 3 alleles (3 ORF): TRDD1*01 ORF, TRDD3*01 ORF and TRDD1*02 ORF.

Update of the Ovis aries (sheep) TRDJ gene and allele nomenclature:

TRDJ gene and allele old name	TRDJ gene and allelle new name
TRDJ1-1*01	TRDJ1*01
TRDJ1-2*01	TRDJ4*01
TRDJ1-3*01	TRDJ2*01
TRDJ1-4*01	TRDJ3*01

TRDJ1*01, TRDJ2*01, TRDJ3*01 and TRDJ4*01 reference sequence is IMGT000048.

Update of the Ovis aries (sheep) TRDC gene and allele nomenclature:

TRDC gene and allele old name	TRDC gene and allelle new name
TRDC*01	TRDC*02

TRDC*01 reference sequence is IMGT000048.

27 May 2020 - Update of the Bos taurus (bovine) TRDD gene and allele nomenclature:

TRDD gene and allele old name TRDD gene and allelle new name

TRDD9*01 TRDD5*01

TRDD5*01 TRDD6*01

TRDD6*01 TRDD7*01

TRDD7*01 TRDD8*01

TRDD8*01 TRDD9*01
15 May 2020 - Update of the Camelus dromedarius (Arabian camel) TRDV gene and allele nomenclature:

TRDV gene and allele old name TRDV gene and allelle new name

TRDV4S1*01 TRDV3S1*01
6 May 2020 - Update of the Camelus dromedarius (Arabian camel) IGK reference directory:
- IMGT reference accession number of Camelus dromedarius (Arabian camel) IGKC*01 genes and alleles is HE653115 in IMGT/LIGM-DB.
30 March 2020
- Update of the Equus caballus (horse) IGHV reference directory:
  Addition of 4 genes and 14 alleles (8 F, 1 ORF, 5 P): IGHV1S1*01 F, IGHV1S2*01 F, IGHV1S4*01 ORF, IGHV3-80*02 P, IGHV4-17*02 F, IGHV4-20*02 P, IGHV4-31*02 F, IGHV4-37*02 P, IGHV4-39*02 F,IGHV4-39D*02 F, IGHV4-76*02 F, IGHV4-79*02 P, IGHV4S1*01 F, IGHV7-36*02 P.
21 April 2020 - Update of the Homo sapiens (human) IGLV reference directory :
- Addition of 7 new alleles (7 F) : IGLV1-47*03 F, IGLV3-10*03 F, IGLV3-19*02 F, IGLV3-21*04 F, IGLV3-22*03 F, IGLV4-60*04 P, IGLV6-57*03 F (IMGT-NC_Report_2019-16-1031_Homsap_IGLV).
- Addition of 4 new genes and alleles (4 P): IGLV(II)-24-1*01 P, IGLV(III)-59-1*01 P, IGLV(III)-60-1*01 P, IGLV(IV)-55-1*01 P.
- Addition of 5 new genes and alleles (5 P): IGLV3-24*03 P, IGLV(I)-20*02 P, IGLV(IV)-53*02 P, IGLV(VI)-22-1*02 P, IGLV(VI)-22-1*03 P.
- Update of IGLV3-25*03 reference sequence.
26 March 2020 - Update of the Ovis aries (sheep) IGL reference directory:
- Addition of 1 VPREB3 gene and allele (1 F) : VPREB3*01 F.
- Addition of 1 IGLL3 gene and allele (1 F) : IGLL3*01 F.
23 March 2020 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of 7 IGHV new alleles (7 F): IGHV1-2*07 F, IGHV1-3*05 F, IGHV1-69*19 F, IGHV3-7*05 F, IGHV3-21*06 F, IGHV3-64D*08 F, IGHV3-64D*09 F
13 March 2020 - Update of the Bos taurus (bovine) TRA/TRD reference directory:
- Update of TRAJ54*01 reference sequence.
9 March 2020
- Update of the Homo sapiens (human) IGLV reference directory: IGLV2-NL1*01 is renamed IGLV2-34*02 (reference sequence Z22209).
- Update of the Bos taurus (bovine) TRA/TRD reference directory: update of the IMGT numbering for Bos taurus (bovine) TRDV1-27*02.
3 March 2020 - Update of the Bos taurus (bovine) TRA/TRD reference directory:
- Update of the IMGT numbering for Bos taurus (bovine) TRAV5*03, TRAV9-6*02, TRAV12-2*03, TRAV13-1*02, TRAV13-4*02, TRAV18-1*02, TRDV1-27*02, TRDV5-1*02, TRDV5-1*03 and TRDC*01.
- Update of the Bos taurus (bovine) TRA reference directory: deletion of TRAJ4*02 reference sequence.

TRDD gene and allele old name	TRDD gene and allelle new name
TRDD9*01	TRDD5*01
TRDD5*01	TRDD6*01
TRDD6*01	TRDD7*01
TRDD7*01	TRDD8*01
TRDD8*01	TRDD9*01

TRDV gene and allele old name	TRDV gene and allelle new name
TRDV4S1*01	TRDV3S1*01

2 March 2020 - Update of the Bos taurus (bovine) TRA/TRD reference directory:

Addition of 80 TRAV alleles (44 F, 5 ORF and 31 P): TRAV3-3*02 P, TRAV5*02 F, TRAV5*03 F, TRAV6*02 P, TRAV8-1*02 F, TRAV8-1*03 F, TRAV8-3*02 P, TRAV8-3*03 P, TRAV9-1*02 F, TRAV9-1*03 F, TRAV9-6*02 F, TRAV12-2*02 F, TRAV12-2*03 F, TRAV13-1*02 F, TRAV13-3*02 P, TRAV13-3*03 P, TRAV13-4*02 F, TRAV14-3*02 P, TRAV14-3*03 F, TRAV14-4*02 ORF, TRAV17-2*02 F, TRAV18-1*02 ORF, TRAV18-1*03 F, TRAV18-3*02 P, TRAV19-3*02 F, TRAV19-3*03 ORF, TRAV19-4*02 P, TRAV20-1*02 F, TRAV21-3*02 F, TRAV21-3*03 F, TRAV22-1*02 ORF, TRAV22-1*03 F, TRAV22-5*02 P, TRAV22-7*02 F, TRAV22-7*03 P, TRAV22-9*02 P, TRAV22-14*02 F, TRAV23-1*02 F, TRAV23-4*02 P, TRAV23-6*02 P, TRAV23-7*02 P, TRAV23-8D*02 P, TRAV23-11*02 P, TRAV23-12*02 P, TRAV24-2*02 F, TRAV24-5*02 P, TRAV24-6*02 P, TRAV25-8*02 F, TRAV25-12*02 P, TRAV25-13*02 F, TRAV26*02 P, TRAV26*03 P, TRAV27*02 ORF, TRAV28-1*02 F, TRAV28-3*02 F, TRAV29-2*02 F, TRAV29-2*03 F, TRAV33-2*02 P, TRAV33-3*02 F, TRAV33-3*03 F, TRAV33-3*04 F, TRAV34-1*02 P, TRAV34-2*02 P, TRAV38-1*02 F, TRAV38-2*02 F, TRAV38-3*02 F, TRAV43-3*02 F, TRAV43-3*03 F, TRAV43-3*04 F, TRAV44-5*02 P, TRAV44-14*02 P, TRAV44-16*02 P, TRAV44-17*02 P, TRAV45-2*02 F, TRAV45-5*02 F, TRAV45-6*02 F, TRAV45-9*02 P, TRAV45-13*02 F, TRAV45-14*02 F, TRAV45-15*02 F.

Update of the Bos taurus (bovine) TRAJ gene and allele nomenclature and functionalities:

TRAJ gene and allele old name	Old functionality	TRAJ gene and allelle new name	New functionality
TRAJ4*01	ORF		F
TRAJ6*01		TRAJ7*01
TRAJ7*01		TRAJ8*01
TRAJ8*01		TRAJ10*01
TRAJ9*01		TRAJ11*01
TRAJ10*01		TRAJ12*01
TRAJ11*01		TRAJ13*01
TRAJ12*01	ORF	TRAJ15*01	P
TRAJ13*01		TRAJ17*01
TRAJ14*01		TRAJ18*01
TRAJ15*01		TRAJ19*01
TRAJ16*01		TRAJ21*01
TRAJ17*01		TRAJ22*01
TRAJ18*01		TRAJ23*01
TRAJ19*01		TRAJ24*01
TRAJ20*01		TRAJ25*01
TRAJ21*01		TRAJ26*01
TRAJ22*01		TRAJ28*01
TRAJ23*01		TRAJ29*01
TRAJ24*01		TRAJ30*01
TRAJ25*01		TRAJ31*01
TRAJ26*01		TRAJ32*01
TRAJ27*01	ORF	TRAJ33*01	F
TRAJ28*01		TRAJ34*01
TRAJ29*01		TRAJ35*01
TRAJ30*01		TRAJ36*01
TRAJ31*01		TRAJ38*01
TRAJ32*01		TRAJ39*01
TRAJ33*01		TRAJ40*01
TRAJ34*01		TRAJ41*01
TRAJ35*01		TRAJ42*01
TRAJ36*01		TRAJ43*01
TRAJ37*01		TRAJ44*01
TRAJ38*01		TRAJ45*01
TRAJ39*01		TRAJ46*02
TRAJ40*01		TRAJ47*01
TRAJ41*01		TRAJ49*01
TRAJ42*01		TRAJ50*01
TRAJ43*01		TRAJ51*01
TRAJ44*01		TRAJ52*01
TRAJ45*01		TRAJ53*01
TRAJ46*01		TRAJ54*01
TRAJ47*01	P	TRAJ55*01	F
TRAJ48*01		TRAJ56*01
TRAJ49*01		TRAJ57*01
TRAJ50*01		TRAJ58*01
TRAJ51*01		TRAJ59*01
TRAJ52*01		TRAJ60*01

TRAJ7*01, TRAJ8*01, TRAJ10*01, TRAJ11*01, TRAJ12*01, TRAJ13*01, TRAJ15*01, TRAJ17*01, TRAJ18*01, TRAJ19*01, TRAJ21*01, TRAJ22*01, TRAJ23*01, TRAJ24*01, TRAJ25*01, TRAJ26*01, TRAJ28*01, TRAJ29*01, TRAJ30*01, TRAJ31*01, TRAJ32*01, TRAJ33*01, TRAJ34*01, TRAJ35*01, TRAJ36*01, TRAJ38*01, TRAJ39*01, TRAJ40*01, TRAJ41*01, TRAJ42*01, TRAJ43*01, TRAJ44*01, TRAJ45*01, TRAJ47*01, TRAJ49*01, TRAJ50*01, TRAJ51*01, TRAJ52*01, TRAJ53*01, TRAJ54*01, TRAJ55*01, TRAJ56*01, TRAJ57*01, TRAJ58*01, TRAJ59*01 and TRAJ60*01 reference sequence is IMGT000049.
Addition of 8 TRAJ genes and 20 alleles (13 F, 1 ORF and 6 P): TRAJ6*01 F, TRAJ9*01 F, TRAJ14*01 P, TRAJ16*01 F, TRAJ20*01 P, TRAJ27*01 ORF, TRAJ37*01 F, TRAJ46*01 F, TRAJ48*01 F, TRAJ4*02 P, TRAJ10*02 F, TRAJ12*02 F, TRAJ14*02 P, TRAJ15*02 P, TRAJ16*02 P, TRAJ26*02 F, TRAJ32*02 F, TRAJ38*02 F, TRAJ40*02 F, TRAJ42*02 F.

Addition of 1 TRAC allele (F): TRAC*02 F.

Update of the Bos taurus (bovine) TRDV gene and allele nomenclature and functionalities:

TRDV gene and allele old name	Old functionality	TRDV gene and allelle new name	New functionality
TRDV1S2-1*01		TRDV1S2*01
TRDV1S2-2*01		TRDV1S2*01
TRDV1S3*01		TRDV1-8*02
TRDV1S4-1*01		TRDV1S4*01
TRDV1S4-2*01		TRDV1S4*01
TRDV1S4-3*01		TRDV1S4*01
TRDV1S5-1*01		TRDV1S5*01
TRDV1S5-2*01		TRDV1S5*01
TRDV1S6-1*01		TRDV1-3*01
TRDV1S6-2*01		TRDV1-3*01
TRDV1S7-1*01		TRDV1-2*01
TRDV1S7-2*01		TRDV1-2*01
TRDV1S8*01		TRDV1-1*01
TRDV1S9*01		TRDV1-28*01
TRDV1S10*01		TRDV1-29*01
TRDV1S11*01		TRDV1-27*01
TRDV1S12*01		TRDV1-25*01
TRDV1S13-1*01		TRDV1-8*01
TRDV1S13-2*01		TRDV1-8*01
TRDV1S14*01		TRDV1-24*01
TRDV1S15-1*01		TRDV1-10D*01
TRDV1S15-2*01		TRDV1-10*01
TRDV1S16*01		TRDV1-33*05
TRDV1S17*01		TRDV1-9*01
TRDV1S18-1*01		TRDV1-4*01
TRDV1S18-2*01		TRDV1-4*01
TRDV1S19*01		TRDV1-11*01
TRDV1S20*01		TRDV1-5*01
TRDV1S21-1*01		TRDV1-7*01
TRDV1S21-2*01		TRDV1-7*01
TRDV1S23*01		TRDV1-29*03
TRDV1S24*01		TRDV1-30*01
TRDV1S25-1*01		TRDV1-17*01
TRDV1S25-2*01		TRDV1-17*01
TRDV1S26*01		TRDV1-31*01
TRDV1S27-1*01		TRDV1-32*01
TRDV1S27-2*01		TRDV1-32*01
TRDV1S28*01		TRDV1-33*03
TRDV1S30*01		TRDV1-1*02
TRDV1S32*01		TRDV1-11*02
TRDV1S33*01		TRDV1-18*01
TRDV1S34*01		TRDV1-17*02
TRDV1S35*01		TRDV1-16*01
TRDV1S36*01		TRDV1-33*04
TRDV1S39*01		TRDV1-12*01
TRDV1S41*01		TRDV1S29*02
TRDV1S42*01		TRDV1-15*02
TRDV1S43*01		TRDV1-14*01
TRDV1S44*01	P	TRDV1-13*02	F
TRDV1S46*01		TRDV1-29*02
TRDV1S47-1*01		TRDV1S47*01
TRDV1S47-2*01		TRDV1S47*01
TRDV1S48*01		TRDV1-15*03
TRDV1S50*01		TRDV1-33*02
TRDV1S51-1*01		TRDV1-33*01
TRDV1S51-2*01		TRDV1-33*01
TRDV1S52-1*01		TRDV1-27*02
TRDV1S52-2*01		TRDV1-27*02
TRDV2S1*01		TRAV33-3*02
TRDV2S2*01		TRAV33-3*03
TRDV2S3*01		TRAV33-3*04
TRDV3S1*01		TRDV5-1*03
TRDV3S2*01		TRDV5-1*02
TRDV4*01		TRDV3*01

TRDV1-1*01, TRDV1-2*01, TRDV1-3*01, TRDV1-4*01, TRDV1-5*01, TRDV1-7*01, TRDV1-8*01, TRDV1-9*01, TRDV1-10*01, TRDV1-10D*01, TRDV1-11*01, TRDV1-12*01, TRDV1-14*01, TRDV1-16*01, TRDV1-17*01, TRDV1-18*01, TRDV1-24*01, TRDV1-25*01, TRDV1-27*01, TRDV1-28*01, TRDV1-29*01, TRDV1-30*01, TRDV1-31*01, TRDV1-32*01, TRDV1-33*01 and TRDV3*01 reference sequence is IMGT000049.
TRDV1S2*01, TRDV1S4*01 and TRDV1S5*01 reference sequence is Btau3.1_Chr10.28.
TRDV1S47*01 reference sequence is Btau3.1_ChrUn.2188.
TRDV1-27*02 reference sequence is Btau3.1_ChrUn.3620.
Addition of 12 TRDV genes and 14 alleles (8 F, 2 ORF and 4 P): TRDV1-6*01 P, TRDV1-13*01 F, TRDV1-15*01 F, TRDV1-19*01 F, TRDV1-20*01 P, TRDV1-21*01 F, TRDV1-22*01 ORF, TRDV1-23*01 P, TRDV1-26*01 P, TRDV2*01 F, TRDV3*01 F, TRDV4*01 ORF, TRDV5-1*01 F, TRDV5-2*01 F.
Deletion of 4 TRDV genes and 49 alleles (47 (F) and 2 (P)): TRDV1S1*02 (F), TRDV1S8*02 (F), TRDV1S8*03 (F), TRDV1S10*02 (F), TRDV1S10*03 (P), TRDV1S10*04 (F), TRDV1S11*02 (F), TRDV1S16*02 (F), TRDV1S17*02 (F), TRDV1S17*03 (F), TRDV1S19*02 (F), TRDV1S19*03 (F), TRDV1S19*04 (F), TRDV1S20*02 (F), TRDV1S20*03 (F), TRDV1S20*04 (F), TRDV1S20*05 (F), TRDV1S23*02 (F), TRDV1S28*02 (F), TRDV1S29*02 (F), TRDV1S32*02 (F), TRDV1S32*03 (F), TRDV1S32*04 (P), TRDV1S33*02 (F), TRDV1S33*03 (F), TRDV1S33*04 (F), TRDV1S34*02 (F), TRDV1S34*03 (F), TRDV1S35*02 (F), TRDV1S38*02 (F), TRDV1S38*03 (F), TRDV1S38*04 (F), TRDV1S38*05 (F), TRDV1S38*06 (F), TRDV1S38*07 (F), TRDV1S38*08 (F), TRDV1S38*09 (F), TRDV1S39*02 (F), TRDV1S40*02 (F), TRDV1S42*02 (F), TRDV1S44*02 (F), TRDV1S44*03 (F), TRDV1S44*04 (F), TRDV1S48*02 (F), TRDV1S55*01 (F), TRDV2S4*01 (F), TRDV3S3*01 (F), TRDV4*02 (F), TRDV5*01 (F).

Update of the Bos taurus (bovine) TRDD gene and allele nomenclature:

TRDD gene and allele old name	TRDD gene and allelle new name
TRDD1*01	TRDD2*01
TRDD2*01	TRDD4*01
TRDD3*01	TRDD6*01
TRDD4*01	TRDD7*01
TRDD5*01	TRDD8*01

TRDD2*01, TRDD4*01, TRDD6*01, TRDD7*01 and TRDD8*01 reference sequence is IMGT000049.
Addition of 4 TRDD genes and alleles (1 F and 3 ORF): TRDD1*01 ORF, TRDD3*01 ORF, TRDD5*01 F, TRDD9*01 ORF.

Update of the Bos taurus (bovine) TRDJ gene and allele nomenclature:

TRDJ gene and allele old name	TRDJ gene and allelle new name
TRDJ2*01	TRDJ4*01

TRDJ1*01, TRDJ3*01 and TRDJ4*01 reference sequence is IMGT000049.
Addition of 1 TRDJ gene and allele (ORF): TRDJ2*01 ORF.

02 March 2020 - Creation of the Ovis aries (sheep) IGL reference directory:
- Addition of 127 IGLV genes and 157 alleles (60 F and 97 P): IGLV1-25*01 F, IGLV1-29*01 F, IGLV1-31*01 P, IGLV1-33*01 F, IGLV1-34*01 P, IGLV1-35*01 P, IGLV1-36*01 F, IGLV1-36*02 F, IGLV1-36*03 F, IGLV1-40*01 F, IGLV1-43*01 P, IGLV1-44*01 P, IGLV1-49*01 F, IGLV1-49*02 F, IGLV1-50*01 P, IGLV1-50*02 P, IGLV1-50*03 P, IGLV1-51*01 P, IGLV1-53*01 F, IGLV1-57*01 F, IGLV1-59*01 F, IGLV1-64*01 F, IGLV1-65*01 P, IGLV1-67*01 F, IGLV1-70*01 P, IGLV1-72*01 P, IGLV1-73*01 P, IGLV1-73*02 P, IGLV1-76*01 F, IGLV1-77*01 P, IGLV1-79*01 F, IGLV1-79*02 F, IGLV1-79*03 F, IGLV1-82*01 F, IGLV1-83*01 P, IGLV1-85*01 P, IGLV1-85*02 P, IGLV1-86*01 P, IGLV1-87*01 P, IGLV1-91*01 F, IGLV1-91*02 F, IGLV1-94*01 F, IGLV1-95*01 P, IGLV1-98*01 F, IGLV1-100*01 F, IGLV1-103*01 F, IGLV1-103*02 F, IGLV1-104*01 P, IGLV1-105*01 F, IGLV1-107*01 F, IGLV1-107*02 P, IGLV1-110*01 F, IGLV1-111*01 P, IGLV1-111*02 P, IGLV1-111*03 P, IGLV1-114*01 P, IGLV1-117*01 F, IGLV1-118*01 P, IGLV1-118*02 P, IGLV1-118*03 P, IGLV1-120*01 F, IGLV1S2*01 F, IGLV1S6*01 F, IGLV1S7*01 F, IGLV1S13*01 F, IGLV1S14*01 F, IGLV1S15*01 F, IGLV2-10*01 F, IGLV2-11*01 F, IGLV2-12*01 F, IGLV2-13*01 F, IGLV2-14*01 P, IGLV2-15*01 P, IGLV2-16*01 F, IGLV2-17*01 F, IGLV2-18*01 P, IGLV2-19*01 F, IGLV2-20*01 F, IGLV2-21*01 F, IGLV2-21*02 F, IGLV2-21*03 P, IGLV2-22*01 F, IGLV2-22*02 F, IGLV3-1*01 P, IGLV3-1*02 P, IGLV3-2*01 F, IGLV3-3*01 F, IGLV3-3*02 P, IGLV3-4*01 F, IGLV3-6*01 P, IGLV3-7*01 F, IGLV3-7*02 F, IGLV3-8*01 F, IGLV3-9*01 P, IGLV3-9*02 P, IGLV4-5*01 P, IGLV5-24*01 P, IGLV5-24*02 P, IGLV5-26*01 P, IGLV5-30*01 P, IGLV5-39*01 P, IGLV5-48*01 P, IGLV5-48*02 P, IGLV5-52*01 P, IGLV5-54*01 P, IGLV5-58*01 P, IGLV5-61*01 P, IGLV5-66*01 F, IGLV5-84*01 F, IGLV5-89*01 P, IGLV5-89*02 P, IGLV5-96*01 P, IGLV5-99*01 P, IGLV5-101*01 P, IGLV5-106*01 P, IGLV5-113*01 F, IGLV5-119*01 F, IGLV5-121*01 P, IGLV5-121*02 P, IGLV8-41*01 P, IGLV8-42*01 P, IGLV8-46*01 F, IGLV8-46*02 P, IGLV8-60*01 P, IGLV8-62*01 P, IGLV8-74*01 P, IGLV8-80*01 P, IGLV8-80*02 P, IGLV8-88*01 P, IGLV8-88*02 P, IGLV8-92*01 P, IGLV8-108*01 P, IGLV8-115*01 P, IGLV9-27*01 P, IGLV9-38*01 P, IGLV9-47*01 P, IGLV9-55*01 P, IGLV9-68*01 P, IGLV(I)-23*01 P, IGLV(I)-90*01 P, IGLV(I)-97*01 P, IGLV(I)-102*01 P, IGLV(IV)-28*01 P, IGLV(IV)-32*01 P, IGLV(IV)-37*01 P, IGLV(IV)-45*01 P, IGLV(IV)-56*01 P, IGLV(IV)-63*01 P, IGLV(IV)-69*01 P, IGLV(IV)-71*01 P, IGLV(IV)-75*01 P, IGLV(IV)-78*01 P, IGLV(IV)-81*01 P, IGLV(IV)-93*01 P, IGLV(IV)-109*01 P, IGLV(IV)-112*01 P, IGLV(IV)-116*01 P.
- Addition of 2 IGLJ genes and 2 alleles (1 F and 1 ORF): IGLJ1*01 ORF, IGLJ2*01 F.
- Addition of 2 IGLC genes and 4 alleles (2 F and 2 P): IGLC1*01 P, IGLC1*02 P, IGLC2*01 F and IGLC2*02 F.
03 March 2020
- Update of Equus caballus (horse) IGHV reference directory: functionality of IGHV3-9*01 is P.
12 February 2020
- Update of the Camelus dromedarius (Arabian camel) IGK reference directory: addition of IGKV7-5*01 reference sequence.
11 February 2020 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of 3 IGHV new alleles (3 F): IGHV4-61*10 F, IGHV1-69*18 F, IGHV4-4*09 F
6 February 2020 - Creation of the Camelus dromedarius (Arabian camel) IGK reference directory:
- Addition of 32 IGKV genes and alleles (8 F, 2 ORF and 22 P): IGKV1-12*01 ORF, IGKV1-15*01 P, IGKV1-20*01 P, IGKV1-23*01 P, IGKV1-26*01 F, IGKV1-29*01 F, IGKV1-7*01 ORF, IGKV2-13*01 P, IGKV2-21*01 P, IGKV2-22*01 P, IGKV2-28*01 F, IGKV2-30*01 F, IGKV2-9*01 P, IGKV3-1*01 P, IGKV3-3*01 P, IGKV4-14*01 P, IGKV4-25*01 P, IGKV4-4*01 F, IGKV4-8*01 P, IGKV5-2*01 F, IGKV6-11*01 P, IGKV6-19*01 P, IGKV6-19D*01 P, IGKV7-5*01 P, IGKV8-10*01 F, IGKV8-18*01 P, IGKV8-18D*01 P, IGKV9-16*01 P, IGKV9-27*01 F, IGKV(II)-17*01 P, IGKV(II)-24*01 P, IGKV(II)-6*01 P.
- Addition of 5 IGKJ genes and alleles (4 F and 1 ORF): IGKJ1*01 ORF, IGKJ2*01 F, IGKJ3*01 F, IGKJ4*01 F, IGKJ5*01 F.
- Addition of 1 IGKC genes and alleles (1 F): IGKC*01 F.

3 February 2020 - Update of the Oryctolagus cuniculus (rabbit) TRAV gene nomenclature:

TRAV gene old name	TRAV gene new name
TRAV44-1*01	TRAV45-1*01
TRAV44-2*01	TRAV45-2*01
TRAV44-3*01	TRAV45-3*01
TRAV44-4*01	TRAV45-4*01
TRAV44-5*01	TRAV45-5*01
TRAV44-6*01	TRAV45-6*01
TRAV42*01	TRAV45-7*01
TRAV45*01	TRAV42*01

30 January 2020
- Update of the Bos taurus (bovine) TRA reference directory: TRAV27*01 is P.
- Update of the IMGT numbering for Bos taurus (bovine) TRAV26*01.
29 January 2020 - Update of the Equus caballus (horse) IGK reference directory:
- Addition of 9 IGK genes and 23 alleles (8 F, 1 ORF and 18 P): IGKV2-27-1*01 P, IGKV4-10-1*01 P, IGKV4-10-2*01 P, IGKV4-12-1*01 P, IGKV4-13-1*01 P, IGKV4-42-1*01 P, IGKV4-5-1*01 F, IGKV4-9-1*01 F, IGKV7-31-1*01 P, IGKV2-48*02 F, IGKV2-29*02 P, IGKV9-54*02 ORF, IGKV2-27-1*02 P, IGKV2-42*02 P, IGKV3-47*02 P, IGKV3-56*02 P, IGKV4-18*02 P, IGKV4-21*02 P, IGKV4-31*02 P, IGKV7-31-1*02 P, IGKV(II)-20*02 P, IGKV(II)-22*02 P, IGKV(II)-55*02 P.
- Addition of 1 IGJ alleles (1 P): IGKJ5*02 P.
- Addition of 1 IGC alleles (1 F): IGKC*02 F.
20 December 2019 - Update of the Bos taurus (bovine) TRA/TRD reference directory:
- Addition of 183 TRAV genes and alleles (84 F, 19 ORF and 80 P): TRAV1*01 F, TRAV2-1*01 ORF, TRAV2-2*01 F, TRAV2-3*01 P, TRAV2-4*01 P, TRAV2-5*01 F, TRAV2-6*01 F, TRAV2-7*01 F, TRAV3-1*01 F, TRAV3-2*01 F, TRAV3-3*01 F, TRAV3-4*01 F, TRAV3-5*01 F, TRAV3-6*01 F, TRAV3-7*01 F, TRAV4*01 P, TRAV5*01 F, TRAV6*01 P, TRAV8-1*01 F, TRAV8-2*01 P, TRAV8-3*01 P, TRAV8-4*01 P, TRAV8-5*01 P, TRAV9-1*01 F, TRAV9-2*01 P, TRAV9-3*01 F, TRAV9-4*01 P, TRAV9-5*01 F, TRAV9-6*01 F, TRAV10-1*01 P, TRAV10-2*01 P, TRAV10-3*01 ORF, TRAV11-1*01 P, TRAV11-2*01 P, TRAV11-3*01 P, TRAV12-1*01 F, TRAV12-2*01 P, TRAV12-3*01 F, TRAV13-1*01 F, TRAV13-2*01 P, TRAV13-3*01 P, TRAV13-4*01 F, TRAV14-1*01 F, TRAV14-2*01 P, TRAV14-3*01 F, TRAV14-4*01 ORF, TRAV16*01 F, TRAV17-1*01 P, TRAV17-2*01 F, TRAV17-3*01 P, TRAV18-1*01 F, TRAV18-2*01 ORF, TRAV18-3*01 P, TRAV18-4*01 F, TRAV18-5*01 ORF, TRAV19-1*01 F, TRAV19-2*01 F, TRAV19-3*01 P, TRAV19-4*01 P, TRAV20-1*01 F, TRAV20-2*01 P, TRAV20-3*01 F, TRAV20-4*01 ORF, TRAV21-1*01 ORF, TRAV21-2*01 P, TRAV21-3*01 F, TRAV21-4*01 F, TRAV22-1*01 F, TRAV22-2*01 F, TRAV22-3*01 ORF, TRAV22-4*01 F, TRAV22-5*01 P, TRAV22-6*01 P, TRAV22-7*01 P, TRAV22-8*01 F, TRAV22-9*01 P, TRAV22-10*01 ORF, TRAV22-11*01 F, TRAV22-12*01 P, TRAV22-13*01 P, TRAV22-14*01 F, TRAV22-15*01 ORF, TRAV22-16*01 F, TRAV23-1*01 F, TRAV23-2*01 P, TRAV23-3*01 P, TRAV23-4*01 P, TRAV23-5*01 P, TRAV23-6*01 P, TRAV23-7*01 P, TRAV23-8*01 P, TRAV23-8D*01 ORF, TRAV23-9*01 P, TRAV23-10*01 P, TRAV23-11*01 ORF, TRAV23-12*01 P, TRAV24-1*01 P, TRAV24-1D*01 P, TRAV24-2*01 ORF, TRAV24-3*01 P, TRAV24-4*01 F, TRAV24-5*01 P, TRAV24-6*01 P, TRAV25-1*01 F, TRAV25-2*01 P, TRAV25-3*01 P, TRAV25-3D*01 P, TRAV25-4*01 F, TRAV25-5*01 P, TRAV25-6*01 P, TRAV25-7*01 P, TRAV25-8*01 F, TRAV25-9*01 P, TRAV25-10*01 P, TRAV25-11*01 P, TRAV25-12*01 F, TRAV25-13*01 F, TRAV25-14*01 ORF, TRAV26*01 P, TRAV27*01 ORF, TRAV28-1*01 F, TRAV28-2*01 P, TRAV28-3*01 F, TRAV29-1*01 ORF, TRAV29-2*01 F, TRAV33-1*01 P, TRAV33-2*01 P, TRAV33-3*01 P, TRAV34-1*01 P, TRAV34-2*01 P, TRAV35-1*01 F, TRAV35-2*01 F, TRAV36-1*01 P, TRAV36-2*01 F, TRAV37-1*01 P, TRAV37-2*01 P, TRAV38-1*01 F, TRAV38-2*01 F, TRAV38-3*01 F, TRAV38-4*01 F, TRAV38-5*01 F, TRAV38-6*01 F, TRAV39-1*01 F, TRAV39-2*01 ORF, TRAV40*01 P, TRAV41*01 F, TRAV43-1*01 F, TRAV43-2*01 F, TRAV43-3*01 F, TRAV44-1*01 F, TRAV44-2*01 P, TRAV44-3*01 F, TRAV44-4*01 F, TRAV44-5*01 P, TRAV44-6*01 F, TRAV44-7*01 P, TRAV44-8*01 F, TRAV44-9*01 F, TRAV44-10*01 F, TRAV44-11*01 P, TRAV44-12*01 P, TRAV44-13*01 P, TRAV44-14*01 P, TRAV44-15*01 ORF, TRAV44-16*01 F, TRAV44-17*01 P, TRAV44-18*01 F, TRAV45-1*01 P, TRAV45-2*01 F, TRAV45-3*01 F, TRAV45-4*01 F, TRAV45-5*01 F, TRAV45-6*01 F, TRAV45-7*01 F, TRAV45-8*01 F, TRAV45-9*01 P, TRAV45-10*01 ORF, TRAV45-11*01 F, TRAV45-12*01 F, TRAV45-13*01 P, TRAV45-14*01 P, TRAV45-15*01 F, TRAV46*01 P.
- TRAC*01 reference sequence is IMGT000049.
- TRDC*01 reference sequence is IMGT000049.
17 December 2019 - Creation of the Equus caballus (horse) IGK reference directory:
- Addition of 57 IGKV genes and alleles (14 F, 2 ORF and 41 P): IGKV1-25*01 P, IGKV1-36*01 F, IGKV2-24*01 P, IGKV2-28*01 F, IGKV2-29*01 P, IGKV2-33*01 F, IGKV2-39*01 F, IGKV2-40*01 P, IGKV2-41*01 P, IGKV2-42*01 P, IGKV2-45*01 F, IGKV2-46*01 F, IGKV2-48*01 F, IGKV2-49*01 P, IGKV3-35*01 P, IGKV3-47*01 P, IGKV3-52*01 P, IGKV3-56*01 P, IGKV4-1*01 F, IGKV4-11*01 P, IGKV4-12*01 P, IGKV4-13*01 P, IGKV4-15*01 P, IGKV4-17*01 P, IGKV4-18*01 F, IGKV4-19*01 P, IGKV4-2*01 F, IGKV4-21*01 P, IGKV4-26*01 P, IGKV4-27*01 P, IGKV4-31*01 P, IGKV4-4*01 P, IGKV4-5*01 F, IGKV4-7*01 P, IGKV4-8*01 F, IGKV4-9*01 F, IGKV5-43*01 F, IGKV6-38*01 ORF, IGKV9-37*01 P, IGKV9-54*01 ORF, IGKV(I)-44*01 P, IGKV(I)-53*01 P, IGKV(II)-10*01 P, IGKV(II)-14*01 P, IGKV(II)-16*01 P, IGKV(II)-16D*01 P, IGKV(II)-20*01 P, IGKV(II)-22*01 P, IGKV(II)-3*01 P, IGKV(II)-30*01 P, IGKV(II)-32*01 P, IGKV(II)-34*01 P, IGKV(II)-50*01 P, IGKV(II)-51*01 P, IGKV(II)-55*01 P, IGKV(II)-6*01 P, IGKV(III)-23*01 P.
- Addition of 5 IGKJ genes and alleles (4 F and 1 P): IGKJ1*01 F, IGKJ2*01 F, IGKJ3*01 F, IGKJ4*01 F, IGKJ5*01 P.
- Addition of 1 IGKC genes and alleles (1 F): IGKC*01 F.
12 December 2019 - Creation of the Equus caballus (horse) IGH reference directory:
- Addition of 41 IGHV genes and alleles (18 F, 7 ORF, 16 P): IGHV1-43*01 ORF, IGHV1-43D*01 ORF, IGHV1-5*01 F, IGHV1-81*01 F, IGHV2-74*01 F, IGHV2-91*01 F, IGHV3-69*01 P, IGHV3-71*01 ORF, IGHV3-73*01 ORF, IGHV3-80*01 P, IGHV3-9*01 F, IGHV3-92*01 F, IGHV4-10*01 P, IGHV4-11*01 F, IGHV4-17*01 F, IGHV4-20*01 P, IGHV4-20D*01 P, IGHV4-20N*01 P, IGHV4-21*01 ORF, IGHV4-23*01 F, IGHV4-31*01 F, IGHV4-37*01 P, IGHV4-37D*01 P, IGHV4-39*01 F, IGHV4-39D*01 F, IGHV4-40*01 P, IGHV4-49*01 ORF, IGHV4-49D*01 ORF, IGHV4-49N*01 ORF, IGHV4-63*01 P, IGHV4-64*01 P, IGHV4-66*01 F, IGHV4-68*01 P, IGHV4-70*01 F, IGHV4-76*01 F, IGHV4-79*01 P, IGHV4-83*01 P, IGHV4-86*01 F, IGHV4-96*01 F, IGHV5-78*01 ORF, IGHV7-36*01 P, IGHV7-36D*01 P, IGHV9-77*01 F.
- Addition of 9 IGHJ genes and alleles (7 F, 2 ORF): IGHJ1*01 F, IGHJ2*01 ORF, IGHJ3*01 F, IGHJ4*01 F, IGHJ5*01 F, IGHJ6*01 F, IGHJ7*01 F, IGHJ8*01 F, IGHJ9*01 ORF.
- Addition of 40 IGHD genes and alleles (26 F, 214 ORF): IGHD1*01 F, IGHD10*01 ORF, IGHD11*01 F, IGHD12*01 F, IGHD13*01 F, IGHD14*01 F, IGHD15*01 F, IGHD16*01 F, IGHD17*01 ORF, IGHD18*01 F, IGHD19*01 ORF, IGHD2*01 F, IGHD20*01 ORF, IGHD21*01 F, IGHD22*01 ORF, IGHD23*01 ORF, IGHD24*01 ORF, IGHD25*01 ORF, IGHD26*01 ORF, IGHD27*01 ORF, IGHD28*01 ORF, IGHD29*01 F, IGHD3*01 F, IGHD30*01 ORF, IGHD31*01 F, IGHD32*01 F, IGHD33*01 F, IGHD34*01 F, IGHD35*01 F, IGHD36*01 F, IGHD37*01 F, IGHD38*01 F, IGHD39*01 ORF, IGHD4*01 F, IGHD40*01 F, IGHD5*01 F, IGHD6*01 F, IGHD7*01 F, IGHD8*01 ORF, IGHD9*01 F.
12 December 2019
- Update of the Oryctolagus cuniculus (rabbit) TRDV gene nomenclature:
TRDV gene old name TRDV gene new name

TRDV2*01 TRDV5*01
- Update of the Tursiops truncatus (Bottlenose dolphin) TRDV gene nomenclature:
TRDV gene old name TRDV gene new name

TRDV4*01 TRDV3*01

TRDV5*01 TRDV4*01
11 December 2019 - Creation of the Macaca mulatta (Rhesus monkey) TRG reference directory:
- Addition of 12 TRGV genes and alleles (4 F, 2 ORF and 6 P): TRGV1*01 ORF, TRGV2*01 F, TRGV3*01 F, TRGV6*01 P, TRGV8*01 F, TRGVA*01 P, TRGV9*01 F, TRGV10*01 ORF, TRGVB*01 P, TRGV11*01 P, TRGVC*01 P, TRGVD*01 P.
- Addition of 5 TRGJ genes and alleles (2 F, 2 ORF and 1 P): TRGJ1-1*01 ORF, TRGJ1-2*01 F, TRGJ2-1*01 ORF, TRGJ2-2*01 P, TRGJ2-3*01 F.
- Addition of 2 TRGC genes and alleles (2 F): TRGC1*01 F and TRGC2*01 F.
06 December 2019
- Update of the IMGT numbering for Homo sapiens (human) TRGV10*02.
04 December 2019
- Update of the IMGT numbering for Canis lupus familiaris (dog) TRAV46*01.
- Update of the IMGT numbering for Felis catus (domestic cat) TRAV46*01.
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) TRAV46*01 and TRAV46*02.
03 December 2019
- Update of the IMGT numbering for Oryctolagus cuniculus (rabbit) TRAV4*01.
- Update of the IMGT numbering for Oryctolagus cuniculus (rabbit) TRAV26*01.
- Update of the IMGT numbering for Oryctolagus cuniculus (rabbit) TRAV46*01.
28 November 2019 - Update of the Homo sapiens (human) TRA/TRD reference directory:
- Addition of 6 TRAV new genes and 9 alleles: TRAV11-1*01 P, TRAV14-1*01 P, TRAV14-1*02 P, TRAV46*01 P, TRAVA*01 P, TRAVA*02 P, TRAVB*01 P, TRAVB*02, TRAVC*01 P
- Addition of 10 TRAV new alleles: TRAV1-2*03, TRAV6*07, TRAV8-2*03, TRAV10*02, TRAV23/DV6*05, TRAV27*03, TRAV29/DV5*04, TRAV30*05, TRAV35*03, TRAV36/DV7*05
- Addition of 5 TRAJ new alleles: TRAJ8*02, TRAJ16*02, TRAJ24*03, TRAJ32*02, TRAJ37*02

21 November 2019 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of 3 IGHV new alleles (3 F): IGHV3-21*05 F, IGHV3-53*05 F, IGHV3-7*04 F

12 November 2019 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of 6 IGHV new alleles (3 F, 3 P): IGHV3-33*07 F, IGHV4-59*13 F, IGHV5-51*07 F, IGHV6-1*03 P, IGHV7-34-1*03 P, IGHV8-51-1*03 P

15 October 2019
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1-10*01.
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1D-4-2*01.
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1D-15-2*01.
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1S2*01.
15 October 2019 - Update of the Oncorhynchus mykiss (rainbow trout) IGH reference directory:
- Addition of 2 IGHJ genes and alleles (2 F): IGHJ5*02 F, IGHJ2T2*02 F
- Addition of 3 IGHD genes and alleles (2 F, 1 ORF): IGHD1T2*02 F, IGHD1*01 F, IGHD3T2*01 ORF
- Addition of 9 IGHC genes and alleles (7 F, 2 P): IGHT1*01 P, IGHT1D*01 P, IGHT2*02 F, IGHM*02 F, IGHM*03 (F), IGHM*04 (F), IGHM*05 (F), IGHM*06 (F), IGHMD*02 F
15 October 2019
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1-10*01.
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1D-4-2*01.
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1D-15-2*01.
10 October 2019
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1-10*01.
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1D-4-2*01.
- Update of the IMGT numbering for Oncorhynchus mykiss (rainbow trout) IGHV1D-15-2*01.
7 October 2019 - Update of the Oncorhynchus mykiss (rainbow trout) IGHV reference directory:
- Addition of 9 IGHV genes and alleles (4 F, 4 ORF and 1 P): IGHV1D-67*01 ORF, IGHV1D-65-3*01 ORF, IGHV15D-53*01 ORF, IGHV1D-34-1*01 ORF, IGHV1-2*02 F, IGHV16-9*02 P, IGHV2-8*02 F, IGHV8-5*02 F, IGHV1S2*01 F
04 October 2019
- Update of the IMGT numbering for Salmo salar (Atlantic salmon) IGHV16D-61*01.
- Update of the IMGT numbering for Salmo salar (Atlantic salmon) IGHV9D-103*01.
27 September 2019 - update of the Oncorhynchus mykiss (rainbow trout) IGHV reference directory:
- Addition of 122 IGHV genes and alleles (3 ORF and 119 P): IGHV16-48-1*01 P, IGHV1-47-1*01 P, IGHV1-46-2*01 P, IGHV10-46-1*01 P, IGHV3-45-1*01 P, IGHV4-44*01 P, IGHV1-43*01 P, IGHV10-40-1*01 P, IGHV6-39-1*01 P, IGHV13-39*01 P, IGHV6-38-1*01 P, IGHV4-36-2*01 P, IGHV8-36-1*01 P, IGHV6-32*01 P, IGHV6-31-3*01 P, IGHV6-31-2*01 P, IGHV6-31-1*01 P, IGHV8-29*01 P, IGHV15-28-1*01 P, IGHV6-26*01 P, IGHV12-24-3*01 P, IGHV3-24-2*01 P, IGHV3-24-1*01 P, IGHV9-24*01 P, IGHV1-22-1*01 P, IGHV3-20-2*01 P, IGHV1-20-1*01 P, IGHV9-19-4*01 P, IGHV1-19-3*01 P, IGHV4-19-2*01 P, IGHV1-19-1*01 P, IGHV6-17-1*01 P, IGHV7-17*01 P, IGHV1-16-2*01 P, IGHV4-16-1*01 P, IGHV9-16*01 P, IGHV3-14-2*01 P, IGHV4-14-1*01 P, IGHV11-13-1*01 P, IGHV10-12*01 P, IGHV11-10-1*01 P, IGHV9-7-2*01 P, IGHV7-7-1*01 P, IGHV1-7*01 P, IGHV4-6*01 P, IGHV6-3*01 P, IGHV4-1*01 P, IGHV1D-15-2*01 P, IGHV1D-4-2*01 P, IGHV2D-78-1*01 P, IGHV15D-78*01 P, IGHV1D-77*01 P, IGHV4D-75-1*01 P, IGHV3D-75*01 P, IGHV1D-74*01 P, IGHV1D-71-1*01 P, IGHV1D-70-1*01 P, IGHV2D-69-1*01 P, IGHV15D-66*01 P, IGHV6D-65-2*01 P, IGHV11D-65-1*01 P, IGHV1D-65*01 P, IGHV6D-64*01 P, IGHV11D-63-1*01 P, IGHV1D-63*01 P, IGHV1D-59*01 P, IGHV1D-55-1*01 P, IGHV16D-55*01 P, IGHV2D-52-1*01 P, IGHV2D-52*01 P, IGHV1D-48*01 P, IGHV1D-46-3*01 P, IGHV6D-46-2*01 P, IGHV11D-46-1*01 P, IGHV1D-46*01 P, IGHV11D-45-1*01 P, IGHV1D-42*01 P, IGHV16D-41*01 P, IGHV15D-40-2*01 P, IGHV16D-40-1*01 P, IGHV3D-39-1*01 P, IGHV1D-39*01 P, IGHV16D-34*01 P, IGHV2D-33*01 P, IGHV15D-32*01 P, IGHV6D-31*01 P, IGHV2D-29-1*01 P, IGHV2D-29*01 P, IGHV15D-27-3*01 P, IGHV11D-27-2*01 P, IGHV9D-27-1*01 P, IGHV6D-27*01 P, IGHV1D-25*01 P, IGHV6D-24-1*01 P, IGHV7D-23-1*01 P, IGHV1D-22*01 P, IGHV1D-21-1*01 P, IGHV1D-21*01 P, IGHV8D-20*01 P, IGHV6D-19*01 P, IGHV6D-18-1*01 P, IGHV6D-18*01 P, IGHV7D-17-1*01 P, IGHV4D-16-1*01 P, IGHV6D-15-3*01 P, IGHV3D-15-1*01 P, IGHV1D-14*01 P, IGHV5D-11-1*01 P, IGHV6D-10*01 P, IGHV6D-8*01 P, IGHV8D-6-1*01 P, IGHV1D-5-1*01 P, IGHV6D-4-5*01 P, IGHV9D-4-4*01 P, IGHV3D-4-3*01 P, IGHV3D-4-1*01 P, IGHV1D-3*01 P, IGHV6D-1-1*01 P, IGHV16D-1*01 P, IGHV15D-53*01 ORF, IGHV1D-65-3*01 ORF, IGHV1D-67*01 ORF.
11 September 2019 - creation of the Oncorhynchus mykiss (rainbow trout) IGHD reference directory:
- Addition of 31 IGHD genes and alleles (27 F, 2 ORF and 2 P): IGHD01 F, IGHD01D P, IGHD02D F, IGHD03D F, IGHD04D P, IGHD05D F, IGHD06D F, IGHD07D F, IGHD08D F, IGHD1 F, IGHD1D F, IGHD1T1 F, IGHD1T1D F, IGHD1T2 F, IGHD2 F, IGHD2D F, IGHD2T1 F, IGHD2T1D F, IGHD2T2 F, IGHD3 F, IGHD3D F, IGHD3T1 F, IGHD3T1D ORF, IGHD4 F, IGHD4D F, IGHD4T1D F, IGHD5 F, IGHD5D F, IGHD5T1D ORF, IGHD6 F, IGHD6D F.
5 September 2019
- Update of Felis catus (domestic cat) IGK reference directory: IGKV8-3*01 functionnality is F.
3 September 2019
- Update of the IMGT numbering for Capra hircus (goat) IGLV1-23*01.
22 August 2019 - Update of the Bos taurus (bovine) IGL reference directory:
- Addition of IGLJ orphon on chromosome 17 (2 ORF, 1 P): IGLJ/OR17-1 P, IGLJ/OR17-2 ORF, IGLJ/OR17-3 ORF.
- Addition of IGLC orphon on chromosome 17 (1 ORF, 2 P): IGLC/OR17-1 P, IGLC/OR17-2 ORF, IGLC/OR17-3 P.
05 August 2019 - Creation of the Oncorhynchus mykiss (rainbow trout) IGH reference directory:
- Addition of 78 IGHV genes and alleles (42 F, 14 ORF and 22 P): IGHV1-10*01 ORF, IGHV1-13*01 F, IGHV1-18*01 F, IGHV1-2*01 F, IGHV1-21*01 P, IGHV1-36*01 F, IGHV1-39*01 F, IGHV1-41*01 P, IGHV1-42*01 F, IGHV10-47*01 F, IGHV10D-26*01 F, IGHV10D-7*01 F, IGHV10D-9*01 F, IGHV11-25*01 F, IGHV12D-36*01 F, IGHV12D-56*01 F, IGHV12D-71*01 F, IGHV14-33*01 P, IGHV15-48*01 P, IGHV15D-49*01 P, IGHV15D-54*01 F, IGHV15D-69*01 P, IGHV16-14*01 ORF, IGHV16-37*01 ORF, IGHV16-38*01 P, IGHV16-9*01 P, IGHV16D-79*01 P, IGHV1D-12*01 P, IGHV1D-15*01 ORF, IGHV1D-16*01 F, IGHV1D-17*01 F, IGHV1D-35*01 F, IGHV1D-38*01 P, IGHV1D-4*01 ORF, IGHV1D-70*01 F, IGHV1D-73*01 F, IGHV2-27*01 P, IGHV2-28*01 F, IGHV2-8*01 F, IGHV2D-11*01 F, IGHV2D-28*01 F, IGHV2D-50*01 ORF, IGHV2D-51*01 P, IGHV2D-68*01 ORF, IGHV3-20*01 F, IGHV3D-30*01 ORF, IGHV4-22*01 P, IGHV4D-13*01 P, IGHV4D-23*01 F, IGHV4D-24*01 F, IGHV4D-37*01 P, IGHV4D-43*01 F, IGHV4D-58*01 P, IGHV4D-60*01 F, IGHV4D-72*01 P, IGHV6-31*01 ORF, IGHV6-35*01 F, IGHV6-4*01 F, IGHV6D-40*01 F, IGHV6D-47*01 P, IGHV6D-5*01 F, IGHV6D-6*01 P, IGHV6D-76*01 F, IGHV7D-44*01 ORF, IGHV7D-45*01 ORF, IGHV7D-61*01 ORF, IGHV7D-62*01 ORF, IGHV8-11*01 P, IGHV8-19*01 ORF, IGHV8-30*01 F, IGHV8-40*01 F, IGHV8-46*01 F, IGHV8-5*01 F, IGHV9-15*01 F, IGHV9-23*01 F, IGHV9-34*01 P, IGHV9-45*01 F, IGHV9D-2*01 F.
- Addition of 19 IGHJ genes and alleles (17 F, 2 ORF): IGHJ1*01 F, IGHJ1D*01 F, IGHJ1T1*01 F, IGHJ1T1D*01 F, IGHJ1T2*01 F, IGHJ2*01 F, IGHJ2D*01 ORF, IGHJ2T1*01 F, IGHJ2T1D*01 F, IGHJ2T2*01 F, IGHJ3*01 F, IGHJ3D*01 F, IGHJ4*01 F, IGHJ4D*01 F, IGHJ5*01 F, IGHJ5D*01 F, IGHJ6*01 ORF, IGHJ6D*01 F, IGHJ7D*01 F.
- Addition of 3 IGHC gene and allele (3 F): IGHM*01 F, IGHMD*01 F, IGHT2*01 F.
31 July 2019 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of 15 IGHV new alleles (9 F, 6 P): IGHV(II)-60-1*02 P, IGHV1-3*03 F, IGHV1-46*04 F, IGHV1-68*02 P, IGHV2-70*18 F, IGHV2-70*19 F, IGHV3-20*04 F, IGHV3-57*03 P, IGHV3-60*03 P, IGHV3-64*07 F, IGHV3-71*04 P, IGHV4-59*11 F, IGHV4-61*09 F, IGHV(II)-62-1*03 P, IGHV3-62*04 F
24 July 2019
- Update of the Felis catus (domestic cat) TRB reference directory: addition of TRBJ1-6*01 P.
23 July 2019
- Update of the Sus scrofa (pig) TRB reference directory: update of TRBV24*01 reference sequence.
- Update of the IMGT numbering for Capra hircus (goat) IGLV1-57*01.
19 July 2019 - Creation of the Felis catus (domestic cat) IGK reference directory:
- Addition of 18 IGKV genes and alleles (11 F, 1 ORF and 6 P): IGKV1-10*01 F, IGKV1-17*01 F, IGKV2-4*01 F, IGKV2-5*01 F, IGKV2-9*01 F, IGKV2-12*01 F, IGKV2-13*01 F, IGKV2-14*01 F, IGKV2-15*01 P, IGKV4-1*01 F, IGKV4-7*01 P, IGKV5-2*01 P, IGKV6-6*01 F, IGKV8-3*01 P, IGKV8-16*01 F, IGKV9-11*01 P, IGKV9-18*01 ORF, IGKV(II)-8*01 P.
- Addition of 5 IGKJ genes and alleles (5 F): IGKJ1*01 F, IGKJ2*01 F, IGKJ3*01 F, IGKJ4*01 F, IGKJ5*01 F.
- Addition of 1 IGKC gene and allele (F): IGKC*01 F.
18 July 2019
- Update of Felis catus (domestic cat) TRA/TRD reference directory: TRAJ2*01 functionnality is F.
- Update of Felis catus (domestic cat) TRA/TRD reference directory: TRAJ51*01 functionnality is P.
08 July 2019
- Update of the Canis lupus familiaris (dog) TRA/TRD reference directory: addition of TRAV46*01 P.
08 July 2019 - Update of the Macaca mulatta (Rhesus monkey) IGLV reference directory:
- Update of IGLV5S4*01 allele name: Previous IGLV5S4*01 has been assigned to IGLV5-15*02.
25 June 2019 - Update of the Sus scrofa (pig) TRB reference directory:
- Update of the IMGT numbering for Sus scrofa (pig) TRBV: Update of gap position 46A instead of 49A in Susscr TRBV30 gene.
- Update of the IMGT numbering for Sus scrofa (pig) TRBV in IMGT/GENE-DB reference directory sets: Update of gap position 46A instead of 49A in "F+ORF+in-frame P with IMGT gaps" FASTA sequences (Nucleotides, Amino acids).
21 June 2019 - Creation of the Capra hircus (goat) IGL reference directory:
- Addition of 73 IGLV genes and alleles (24 F and 49 P): IGLV(I)-15*01 P, IGLV(I)-26*01 P, IGLV(I)-48*01 P, IGLV(I)-56*01 P, IGLV(I)-61*01 P, IGLV(IV)-20*01 P, IGLV(IV)-29*01 P, IGLV(IV)-40*01 P, IGLV(IV)-45*01 P, IGLV(IV)-52*01 P, IGLV(IV)-68*01 P, IGLV1-16*01 P, IGLV1-17*01 F, IGLV1-21*01 F, IGLV1-23*01 F, IGLV1-27*01 P, IGLV1-30*01 F, IGLV1-31*01 P, IGLV1-34*01 F, IGLV1-37*01 P, IGLV1-38*01 P, IGLV1-39*01 F, IGLV1-42*01 P, IGLV1-44*01 F, IGLV1-46*01 P, IGLV1-47*01 F, IGLV1-53*01 F, IGLV1-54*01 P, IGLV1-57*01 F, IGLV1-59*01 F, IGLV1-62*01 F, IGLV1-63*01 P, IGLV1-64*01 F, IGLV1-69*01 F, IGLV1-70*01 P, IGLV1-72*01 F, IGLV2-10*01 F, IGLV2-11*01 F, IGLV2-12*01 P, IGLV2-13*01 P, IGLV2-14*01 P, IGLV3-1*01 P, IGLV3-2*01 F, IGLV3-3*01 F, IGLV3-4*01 F, IGLV3-6*01 P, IGLV3-7*01 F, IGLV3-8*01 F, IGLV3-9*01 P, IGLV4-5*01 P, IGLV5-18*01 P, IGLV5-22*01 P, IGLV5-25*01 P, IGLV5-43*01 P, IGLV5-49*01 P, IGLV5-55*01 P, IGLV5-58*01 P, IGLV5-60*01 P, IGLV5-65*01 P, IGLV5-71*01 F, IGLV5-73*01 P, IGLV8-24*01 P, IGLV8-28*01 P, IGLV8-32*01 P, IGLV8-33*01 P, IGLV8-36*01 P, IGLV8-41*01 P, IGLV8-51*01 F, IGLV8-67*01 P, IGLV9-19*01 P, IGLV9-35*01 P, IGLV9-50*01 P, IGLV9-66*01 P.
- Addition of 2 IGLJ genes and alleles (1 F and 1 ORF): IGLJ1*01 ORF, IGLJ2*01 F.
- Addition of 2 IGLC genes and alleles (1 F and 1 P): IGLC1*01 P, IGLC2*01 F.
- Addition of 1 VPREB3 gene and allele (1 F) : VPREB3*01 F.
19 June 2019
- Update of the Oryctolagus cuniculus (rabbit) TRA/TRD reference directory: addition of TRAV46*01 P.
- Update of the Tursiops truncatus (Bottlenose dolphin) TRA/TRD reference directory: addition of TRAV46*01 P.
17 June 2019 - Update of the IMGT numbering for Danio rerio (zebrafish) TRAV reference directory:
- Update of the IMGT numbering for Danio rerio (zebrafish) TRAV Addition of 46A corresponding to additional position in Danrer TRAV65-1 gene.
- Update of the IMGT numbering for Danio rerio (zebrafish) TRAV in IMGT/GENE-DB reference directory sets: Addition of 46A in "F+ORF+in-frame P with IMGT gaps" FASTA sequences (Nucleotides, Amino acids).
14 June 2019 - Update of the Macaca mulatta (Rhesus monkey) IGLV reference directory:
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) for IGLV5S4.
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) for IGLV5-15.
14 June 2019 - Update of the Macaca mulatta (Rhesus monkey) TRAV reference directory:
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) TRAV. Update of gap position 77A instead of 76A in Macmul TRAV11-1 gene.
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) TRAV in IMGT/GENE-DB reference directory sets: Update of gap position 77A instead of 76A in "F+ORF+in-frame P with IMGT gaps" FASTA sequences (Nucleotides, Amino acids).
13 June 2019 - Creation of the Felis catus (Domestic cat) TRA/TRD reference directory:
- Addition of 62 TRAV genes and alleles (37 F, 10 ORF and 15 P): TRAV2*01 ORF, TRAV3*01 F, TRAV4*01 ORF, TRAV5*01 F, TRAV6*01 F, TRAV8-1*01 ORF, TRAV8-2*01 F, TRAV8-3*01 F, TRAV8-4*01 F, TRAV8-5*01 F, TRAV8-6*01 F, TRAV8-7*01 F, TRAV9-1*01 P, TRAV9-2*01 ORF, TRAV9-3*01 F, TRAV9-4*01 F, TRAV9-5*01 F, TRAV9-6*01 P, TRAV9-7*01 F,TRAV10*01 F, TRAV11*01 P, TRAV12*01 F, TRAV13-1*01 F, TRAV13-2*01 P, TRAV13-3*01 F, TRAV14-1*01 P, TRAV14-2*01 P, TRAV14-3*01 P, TRAV14-4*01 P, TRAV14-5*01 F, TRAV16*01 F, TRAV17*01 F, TRAV18*01 F, TRAV19*01 F, TRAV20*01 P, TRAV21*01 F, TRAV22*01 ORF, TRAV23*01 F, TRAV24*01 F, TRAV25*01 F, TRAV26*01 ORF, TRAV27*01 ORF, TRAV28*01 ORF, TRAV29*01 F, TRAV30*01 P, TRAV31*01 P, TRAV34*01 ORF, TRAV35*01 F, TRAV36*01 ORF, TRAV37*01 F, TRAV38-1*01 F, TRAV38-2*01 F, TRAV39*01 P, TRAV40*01 F, TRAV41*01 F, TRAV43-1*01 F, TRAV43-2*01 F, TRAV43-3*01 F, TRAV43-4*01 P, TRAV43-5*01 P, TRAV43-5*01 P and TRAV46*01 F.
- Addition of 64 TRAJ genes and alleles (40 F, 22 ORF and 2 P): TRAJ1*01 ORF, TRAJ2*01 ORF, TRAJ3*01 ORF, TRAJ4*01 ORF, TRAJ5*01 F, TRAJ6*01 ORF, TRAJ7*01 F, TRAJ8*01 F, TRAJ9*01 F, TRAJ10*01 ORF, TRAJ11*01 F, TRAJ12*01 ORF, TRAJ13*01 F, TRAJ14*01 ORF, TRAJ15*01 F,TRAJ16*01 F, TRAJ17*01 ORF, TRAJ18*01 F, TRAJ19*01 ORF, TRAJ20*01 F, TRAJ21*01 F, TRAJ22*01 F, TRAJ23*01 F, TRAJ24*01 F, TRAJ25*01 F, TRAJ26*01 F, TRAJ27*01 F, TRAJ28*01 ORF, TRAJ29*01 F, TRAJ30*01 ORF, TRAJ31*01 F, TRAJ32*01 F, TRAJ33*01 F, TRAJ34*01 F, TRAJ35*01 F, TRAJ36*01 F, TRAJ37*01 ORF, TRAJ38*01 F, TRAJ39*01 F, TRAJ40*01 F, TRAJ41*01 ORF, TRAJ42*01 F, TRAJ43*01 F, TRAJ44*01 F, TRAJ45*01 F, TRAJ46*01 ORF, TRAJ47*01 F, TRAJ48*01 F, TRAJ49*01 F, TRAJ50*01 F, TRAJ51*01 ORF, TRAJ52*01 F, TRAJ53*01 F, TRAJ54*01 F, TRAJ55*01 P, TRAJ56*01 F, TRAJ57*01 ORF, TRAJ58*01 ORF, TRAJ59*01 F, TRAJ60*01 ORF, TRAJ61*01 ORF, TRAJ62*01 ORF, TRAJ63*01 ORF and TRAJ64*01 P.
- Addition of 1 TRAC gene and allele (F): TRAC*01 F.
- Addition of 11 TRDV genes and alleles (5 F, 3 ORF and 3 P): TRDV1*01 P, TRDV2-1*01 ORF, TRDV2-2*01 P, TRDV3*01 F, TRDV4*01 ORF, TRDV5-1*01 F, TRDV5-2*01 F, TRDV5-3*01 F, TRDV5-4*01 P, TRDV5-5*01 F, TRDV5-6*01 ORF.
- Addition of 2 TRDD genes and alleles (2 F): TRDD1*01 F and TRDD2*01 F.
- Addition of 5 TRDV genes and alleles (2 F, 2 ORF and 1 P): TRDJ1*01 ORF, TRDJ2*01 ORF, TRDJ3*01 F, TRDJ4*01 F, TRDJ5*01 P.
- Addition of 1 TRDC gene and allele (F): TRDC*01 F.
11 June 2019 - Update of the IMGT numbering for Canis lupus familiaris (dog) TRAV reference directory:
- Update of the IMGT numbering for Canis lupus familiaris (dog) TRAV Addition of 46A corresponding to additional position in Canlupfam TRAV43 subgroup.
- Update of the IMGT numbering for Canis lupus familiaris (dog) TRAV in IMGT/GENE-DB reference directory sets: Addition of 46A in "F+ORF+in-frame P with IMGT gaps" FASTA sequences (Nucleotides, Amino acids).
7 June 2019 - Creation of the Bos taurus (bovine) IGK reference directory:
- Addition of 25 IGKV genes and alleles (6 F, 2 ORF and 17 P): IGKV1-1*01 ORF, IGKV1-4*01 F, IGKV1-5*01 P, IGKV1-21*01 P, IGKV1-25*01 P, IGKV2-6*01 F, IGKV2-7*01 P, IGKV2-9*01 F, IGKV2-10*01 P, IGKV2-12*01 ORF, IGKV2-13*01 P, IGKV2-15*01 F, IGKV2-16*01 P, IGKV2-18*01 F, IGKV2-19*01 P, IGKV2-22*01 P, IGKV2-23*01 P, IGKV3-24*01 P, IGKV8-3*01 F, IGKV(II)-2*01 P, IGKV(II)-8*01 P, IGKV(II)-11*01 P, IGKV(II)-14*01 P, IGKV(II)-17*01 P, IGKV(II)-20*01 P.
- Addition of 5 IGKJ genes and alleles (1 F and 4 ORF): IGKJ1*01 ORF, IGKJ2*01 F, IGKJ3*01 ORF, IGKJ4*01 ORF, IGKJ5*01 ORF.
- Addition of 1 IGKC gene and allele (F): IGKC*01 F.
6 June 2019
- Update of Salmo salar (saumon) IGH reference directory: IGHD5*01 functionnality is F.
- Update of the IMGT numbering for Canis lupus familiaris (dog) TRDV2*01.
5 June 2019 - Update of the Ovis aries (sheep) TRAV gene nomenclature:

TRAV gene old name TRAV gene new name

TRAV43S2*01 TRAV13S2*01
4 June 2019
- Update of the IMGT numbering for Ovis aries (sheep) TRBV5-25*01.
23 May 2019
- Update of the Macaca mulatta (Rhesus monkey) TRA/TRD reference directory:
  - Addition of TRAV46*01 P.
  - Addition of TRAV46*02 P.
- Update of the IMGT numbering for Camelus dromedarius (Arabian camel) TRDV4S1*01.
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) TRDV3*01 and TRDV3*02.
- Update of the IMGT numbering for Oryctolagus cuniculus (rabbit) TRDV3*01.
21 May 2019 - Creation of the Bos taurus (bovine) IGL reference directory:
- Addition of 74 IGLV genes and 93 alleles (35 F, 5 ORF and 53 P): IGLV1-12*01 F, IGLV1-14*01 P, IGLV1-16*01 P, IGLV1-16*02 F, IGLV1-17*01 P, IGLV1-17*02 P, IGLV1-18*01 P, IGLV1-21*01 F, IGLV1-21*02 P, IGLV1-22*01 P, IGLV1-26*01 F, IGLV1-28*01 P, IGLV1-29*01 P, IGLV1-31*01 F, IGLV1-31*02 F, IGLV1-31*03 F, IGLV1-31*04 P, IGLV1-36*01 ORF, IGLV1-40*01 F, IGLV1-40*02 F, IGLV1-41*01 P, IGLV1-41*02 P, IGLV1-43*01 F, IGLV1-46*01 P, IGLV1-47*01 F, IGLV1-47*02 F, IGLV1-47*03 F, IGLV1-47*04 F, IGLV1-47*05 F, IGLV1-48*01 P, IGLV1-51*01 P, IGLV1-52*01 F, IGLV1-53*01 P, IGLV1-55*01 F, IGLV1-57*01 P, IGLV1-58*01 F, IGLV1-59*01 P, IGLV1-60*01 P, IGLV1-61*01 P, IGLV1-63*01 F, IGLV1-64*01 F, IGLV1-66*01 P, IGLV1-66*02 P, IGLV1-67*01 F, IGLV1-67*02 F, IGLV1-67*03 F, IGLV1-67*04 F, IGLV1-70*01 F, IGLV1-71*01 F, IGLV1-73*01 F, IGLV2-6*01 F, IGLV2-7*01 ORF, IGLV2-8*01 P, IGLV2-9*01 F, IGLV3-1*01 P, IGLV3-2*01 F, IGLV3-3*01 F, IGLV3-4*01 F, IGLV3-5*01 F, IGLV5-11*01 P, IGLV5-13*01 P, IGLV5-45*01 ORF, IGLV5-50*01 ORF, IGLV5-62*01 P, IGLV5-72*01 F, IGLV5-74*01 P, IGLV5-74*02 P, IGLV8-19*01 P, IGLV8-19*02 P, IGLV8-24*01 P, IGLV8-27*01 P, IGLV8-32*01 P, IGLV8-37*01 P, IGLV8-38*01 F, IGLV8-44*01 P, IGLV8-49*01 P, IGLV8-54*01 P, IGLV13-23*01 ORF, IGLV(I)-10*01 P, IGLV(I)-35*01 P, IGLV(IV)-15*01 P, IGLV(IV)-15*02 P, IGLV(IV)-20*01 P, IGLV(IV)-25*01 P, IGLV(IV)-30*01 P, IGLV(IV)-33*01 P, IGLV(IV)-34*01 P, IGLV(IV)-39*01 P, IGLV(IV)-42*01 P, IGLV(IV)-56*01 P, IGLV(IV)-65*01 P, IGLV(IV)-68*01 P, IGLV(IV)-69*01 P.
- Addition of 8 IGLJ genes and alleles (5 F and 3 ORF): IGLJ1*01 ORF, IGLJ2*01 F, IGLJ3*01 F, IGLJ4*01 F, IGLJ5*01 ORF, IGLJ7*01 F, IGLJ8*01 F, IGLJ9*01 ORF.
- Addition of 9 IGLC genes and alleles (4 F and 5 P): IGLC1*01 P, IGLC2*01 F, IGLC3*01 F, IGLC4*01 F, IGLC5*01 P, IGLC6*01 P, IGLC7*01 P, IGLC8*01 F, IGLC9*01 P.
17 May 2019 - Update of the Sus scrofa (pig) TRB reference directory:
- Update of TRBJ2-1*01 reference sequence.
16 May 2019 - Update of the Mus musculus (mouse) TRD reference directory:
- Update of the IMGT numbering for Mus musculus (mouse) TRDV5*01, TRDV5*02, TRDV5*03 and TRDV5*04.
15 May 2019
- Update of Salmo salar (saumon) IGH reference directory: IGHV16D-61 functionnality is P.
6 May 2019 - Update of the Sus scrofa (pig) TRB reference directory:
- Update of TRBV2-1*01 reference sequence.
3 May 2019 - Update of the Sus scrofa (pig) IGL reference directory:
- Update of IGLV8-10*01, IGLV8-13*01, IGLV8-16*01, IGLV8-18*01, IGLV8-19*01, IGLV8-19*02, IGLV8-21*01 and IGLV8-21*02 reference sequence.
2 May 2019 - Update of the Homo sapiens (human) IGHV reference directory:
- Update of IGHV4-4*03 reference sequence.
- Addition of 6 IGHV new alleles (6 F): IGHV1-3*04 F, IGHV1-58*03 F, IGHV4-30-4*08 F, IGHV4-31*11 F, IGHV4-59*12 F, IGHV5-51*06 F.
23 April 2019 - Update of Salmo salar (Atlantic Salmon) IGHV reference directory:
- Addition of 3 IGHV genes and alleles (1 F and 2 P):IGHV1-40*02 P, IGHV1D-128*02 F, IGHV1DS4*01 P.
11 April 2019
- Update of Ovis aries (sheep) TRB reference directory: TRBV12-1*01 functionnality is ORF.
10 April 2019 - Creation of the Camelus dromedarius (Arabian camel) TRB reference directory:
- Addition of 27 TRBV genes and 27 alleles (26 F, 1 P): TRBV1*01 F, TRBV10*01 F, TRBV11*01 F, TRBV15S1*01 F, TRBV15S2*01 F, TRBV16*01 F, TRBV19*01 F, TRBV2*01 F, TRBV20*01 F, TRBV21S1*01 F, TRBV21S2*01 F, TRBV21S3*01 P, TRBV22*01 F, TRBV25*01 F, TRBV26*01 F, TRBV27*01 F, TRBV28*01 F, TRBV29*01 F, TRBV3*01 F, TRBV30*01 F, TRBV5S1*01 F, TRBV5S2*01 F, TRBV5S3*01 F, TRBV6*01 F, TRBV7S1*01 F, TRBV7S2*01 F, TRBV8*01 F.
- Addition of 1 TRBD gene and 1 allele (1 F): TRBD1*01 F.
- Addition of 13 TRBJ genes and 13 alleles (12 F, 1 ORF): TRBJ1-1*01 F, TRBJ1-2*01 F, TRBJ1-3*01 F, TRBJ1-4*01 F, TRBJ1-5*01 F, TRBJ1-6*01 F, TRBJ2-2*01 F, TRBJ2-3*01 F, TRBJ2-6*01 ORF, TRBJ3-1*01 F, TRBJ3-2*01 F, TRBJ3-3*01 F, TRBJ3-4*01 F.
- Addition of 3 TRBC genes and 3 alleles (2 F, 1P): TRBC1*01 F, TRBC2*01 P, TRBC3*01 F.
9 April 2019
- Update of the IMGT numbering for Sus scrofa (pig) TRBC1*01, TRBC2*01 and TRBC3*01.
8 April 2019
- Update of the IMGT numbering for Sus scrofa (pig) TRBV12-1*01.
1 April 2019
- Update of the IMGT numbering for Ovis aries (sheep) TRBV1*01.
29 March 2019 - Update of the Sus scrofa (pig) TRB reference directory:
- Functionality of TRBJ1-4*01 is P.
- Functionality of TRBJ3-6*01 is P.
- Functionality of TRBV29*01 is F.
- Update of the IMGT numbering for TRBV1*01.
- Update of TRBV12-1*01 reference sequence.
28 March 2019 - Creation of the Ovis aries (sheep) TRB reference directory:
- Addition of 94 TRBV genes and alleles (46 F, 11 ORF and 37 P): TRBV1*01 F, TRBV2*01 F, TRBV3*01 F, TRBV4*01 F, TRBV5-1*01 P, TRBV5-2*01 F, TRBV5-3*01 ORF, TRBV5-4*01 P, TRBV5-5*01 F, TRBV5-6*01 F, TRBV5-7*01 P, TRBV5-8*01 F, TRBV5-9*01 P, TRBV5-10*01 P, TRBV5-11*01 P, TRBV5-12*01 P, TRBV5-13*01 F, TRBV5-14*01 P, TRBV5-15*01 F, TRBV5-16*01 P, TRBV5-17*01 P, TRBV5-18*01 F, TRBV5-19*01 P, TRBV5-20*01 P, TRBV5-21*01 F, TRBV5-22*01 F, TRBV5-23*01 F, TRBV5-24*01 F, TRBV5-25*01 ORF, TRBV5-26*01 ORF, TRBV5-27*01 P, TRBV5-28*01 F, TRBV5-29*01 F, TRBV5-30*01 ORF, TRBV5-31*01 ORF, TRBV5-32*01 F, TRBV5-33*01 P, TRBV6-1*01 ORF, TRBV6-2*01 F, TRBV6-3*01 P, TRBV6-4*01 P, TRBV6-5*01 F, TRBV6-6*01 F, TRBV6-7*01 P, TRBV6-8*01 P, TRBV6-9*01 F, TRBV6-10*01 P, TRBV6-11*01 P, TRBV6-12*01 F, TRBV6-13*01 P, TRBV6-14*01 ORF, TRBV6-15*01 F, TRBV6-16*01 ORF, TRBV6-17*01 F, TRBV6-18*01 P, TRBV6-19*01 P, TRBV6-20*01 P, TRBV6-21*01 P, TRBV6-22*01 F, TRBV6-23*01 P, TRBV6-24*01 P, TRBV6-25*01 P, TRBV6-26*01 P, TRBV6-27*01 F, TRBV6-28*01 ORF, TRBV6-29*01 F, TRBV6-30*01 ORF, TRBV7-1*01 F, TRBV7-2*01 F, TRBV8*01 P, TRBV10*01 P, TRBV11*01 P, TRBV12-1*01 P, TRBV12-2*01 F, TRBV14*01 F, TRBV15*01 F, TRBV16*01 F, TRBV18*01 P, TRBV19*01 ORF, TRBV20*01 F, TRBV21-1*01 P, TRBV21-2*01 F, TRBV21-3*01 F, TRBV21-4*01 F, TRBV21-5*01 F, TRBV21-6*01 F, TRBV22*01 P, TRBV24*01 F, TRBV25*01 F, TRBV26*01 F, TRBV27*01 P, TRBV28*01 F, TRBV29*01 F, TRBV30*01 F.
- Addition of 3 TRBD genes and 5 alleles (5 F): TRBD1*01 F, TRBD1*02 F, TRBD2*01 F, TRBD3*01 F, TRBD3*02 F.
- Addition of 19 TRBJ genes and 23 alleles (20 F, 1 ORF and 2 P): TRBJ1-1*01 F, TRBJ1-2*01 F, TRBJ1-3*01 ORF, TRBJ1-4*01 F, TRBJ1-5*01 F, TRBJ1-5*02 F, TRBJ1-6*01 F, TRBJ2-1*01 F, TRBJ2-1*02 F, TRBJ2-2*01 F, TRBJ2-3*01 F, TRBJ2-4*01 F, TRBJ2-5*01 F, TRBJ2-6*01 F, TRBJ2-7*01 F, TRBJ3-1*01 F, TRBJ3-2*01 F, TRBJ3-2*02 F, TRBJ3-3*01 F, TRBJ3-4*01 F, TRBJ3-5*01 F, TRBJ3-6*01 P, TRBJ3-6*02 P.
- Addition of 3 TRBC genes and 6 alleles (6 F): TRBC1*01 F, TRBC1*02 F, TRBC2*01 F, TRBC2*02 F, TRBC3*01 F, TRBC3*02 F.
27 March 2019 - Update of the Homo sapiens (human) IGHV reference directory:
- IGHV(III)-51-1*01 is renamed IGHV3-51-1*01
- Update of IGHV7-4-1*01 reference sequence.
- Addition of 18 IGHV new alleles (1F, 17 P): IGHV4-80*02 P, IGHV3-79*02 P, IGHV(II)-78-1*02 P, IGHV(II)-62-1*02P, IGHV3-62*03 P, IGHV3-60*02 P, IGHV(II)-53-1*02 P, IGHV3-51-1*02 F, IGHV(IV)-44-1*02 P, IGHV(III)-44*02 P, IGHV(II)-43-1*02 P, IGHV3-41*02 P, IGHV(III)-16-1*02 P, IGHV1-14*02 P, IGHV(III)-13-1*02 P, IGHV3-6*02 P, IGHV(III)-5-2*02 P, IGHV(III)-2-1*02 P.
- Addition of 2 IGHJ new alleles: IGHJ1P*02 P, IGHJ2P*02.
- Update of sequences of the literature for: IGHG3*10 F, IGHG1*05 F, IGHEP1*04 P, IGHA1*03 F, IGHGP*03 P, IGHG2*06 F, IGHG4*04 F, IGHA2*02 F.
- Addition of 2 IGHC new alleles: IGHA1*03 F and IGHGP*03 P.
27 March 2019 - Update of the Gallus gallus (chicken) IGLV reference directory:
- Update of the Gallus gallus (chicken) IGLV gene nomenclature:
  
  IGLV gene old name IGLV gene new name
  
  IGLV1S6*01 IGLV1-15-1*01
  
  IGLV1S9*01 IGLV1-21-1*01
  
  IGLV1S10*01 IGLV1-21-2*02
- IMGT reference accession number of Gallus gallus (chicken) IGLV genes and alleles IGLV1-15-1*01 and IGLV1-21-1*01 is IMGT000008 in IMGT/LIGM-DB.
- Addition of IGLV1-21-2*01 P.
26 March 2019
- Update of the IMGT numbering for Mustela putorius furo (ferret) TRBV: TRBV1*01, TRBV7-1*01, TRBV7-2*01, TRBV12-1*01, TRBV12-2*01, TRBV16*01, TRBV18*01, TRBV20*01, TRBV21*01, TRBV29*01.
- Update of the IMGT numbering for Oryctolagus cuniculus (rabbit) TRBV: TRBV2-1*01, TRBV2-2*02, TRBV7-1*01, TRBV7-10*01, TRBV7-11*01, TRBV7-13*01, TRBV7-14*01, TRBV7-2*01, TRBV7-3*01, TRBV7-5*01, TRBV7-7*01, TRBV7-8*01, TRBV7-9*01, TRBV12*01, TRBV18*01, TRBV20-1*01, TRBV20-2*01, TRBV21-1*01, TRBV21-2*01, TRBV21-3*01, TRBV21-4*01, TRBV21-5*01, TRBV21-6*01, TRBV21-7*01, TRBV29*01.
21 March 2019 - Update of Homo sapiens (human) IGHC reference directory:
- Addition of 6 IGHC genes and alleles (6 F):
  2 new alleles of the Homo sapiens IGHG2 gene: IGHG2*16 and IGHG2*17
  4 new alleles of the Homo sapiens IGHG4 gene: IGHG4*05, IGHG4*06, IGHG4*07, IGHG4*8
21 March 2019 - Update of the Felis catus (cat) IGL reference directory:
- Addition of gapped sequence for IGLV1-78*01 (P).
19 March 2019 - Update of the Sus scrofa (pig) TRB reference directory:
- Addition of 8 TRBV genes and alleles (8 P): TRBV2-2*01 P, TRBV2-3*01 P, TRBV2-5*01 P, TRBV4-2*01 P, TRBV5-2*01 P, TRBV8*01 P, TRBV22*01 P, TRBV23*01 P.
14 March 2019 - Creation of the Felis catus (cat) TRB reference directory:
- Addition of 33 TRBV genes and alleles (20 F, 4 ORF and 9 P): TRBV1*01 F, TRBV2*01 P, TRBV3*01 F, TRBV4-1*01 F, TRBV4-2*01 F, TRBV5-1*01 P, TRBV5-2*01 F, TRBV5-3*01 F, TRBV5-4*01 F, TRBV6*01 F, TRBV7-1*01 F, TRBV7-2*01 F, TRBV8*01 P, TRBV10*01 F, TRBV11*01 P, TRBV12-1*01 F, TRBV12-2*01 P, TRBV15*01 F, TRBV16*01 P, TRBV17*01 P, TRBV18*01 F, TRBV19*01 ORF, TRBV20*01 F, TRBV21*01 F, TRBV22*01 ORF, TRBV23*01 P, TRBV24*01 F, TRBV25*01 ORF, TRBV26*01 F, TRBV27*01 ORF, TRBV28*01 P, TRBV29*01 F, TRBV30*01 F.
- Addition of 2 TRBD genes and alleles (2 F): TRBD1 and TRBD2.
- Addition of 11 TRBJ genes and alleles (8 F, 1 ORF and 2 P): TRBJ1-1 F, TRBJ1-2 F, TRBJ1-3 ORF, TRBJ1-4 P, TRBJ1-5 F, TRBJ2-1 F, TRBJ2-2 F, TRBJ2-3 F, TRBJ2-4 F, TRBJ2-5 P and TRBJ2-6 F.
- Addition of 2 TRBC genes and alleles (2 F): TRBC1 and TRBC2.
8 March 2019 - Update of the Sus scrofa (pig) TRB reference directory:
- Update of the IMGT numbering for Sus scrofa (pig) TRBV: Addition of 49A corresponding to additional position in Susscr TRBV30 gene.
- Update of the IMGT numbering for Sus scrofa (pig) TRBV in IMGT/GENE-DB reference directory sets: Addition of 49A in "F+ORF+in-frame P with IMGT gaps" FASTA sequences (Nucleotides, Amino acids).
4 March 2019 - Creation of the Felis catus (cat) IGL reference directory:
- Addition of 94 IGLV genes and alleles (32 F, 2 ORF and 60 P): IGLV5-79*01 F, IGLV1-76*01 P, IGLV1-73*01 P, IGLV1-72*01 P, IGLV5-71*01 F, IGLV1-70*01 F, IGLV1-69*01 P, IGLV5-68*01 F, IGLV5-66*01 F, IGLV1-63*01 F, IGLV1-61*01 F, IGLV1-59*01 P, IGLV5-58*01 P, IGLV1-56*01 F, IGLV5-55*01 F, IGLV1-51*01 F, IGLV1-50*01 P, IGLV5-49*01 F, IGLV5-48*01 F, IGLV1-47*01 P, IGLV5-46*01 F, IGLV1-47D*01 P, IGLV1-44*01 ORF, IGLV1-42*01 F, IGLV1-41*01 ORF, IGLV1-40*01 F, IGLV5-38*01 P, IGLV1-37*01 F, IGLV1-36*01 F, IGLV1-35*01 P, IGLV5-34*01 F, IGLV1-32*01 F, IGLV5-30*01 F, IGLV12-26*01 F, IGLV2-24*01 F, IGLV3-23*01 F, IGLV3-20*01 F, IGLV3-17*01 F, IGLV4-15*01 F, IGLV3-13*01 F, IGLV3-11*01 F, IGLV3-10*01 P, IGLV3-8-1*01 P, IGLV3-7*01 F, IGLV3-6*01 F, IGLV3-5*01 F, IGLV3-4*01 P, IGLV3-2*01 F, IGLV1-78*01 P, IGLV5-77*01 P, IGLV5-75*01 P, IGLV5-74*01 P, IGLV1-72-1*01 P, IGLV8-67*01 P, IGLV1-65*01 P, IGLV5-64*01 P, IGLV1-62-1*01 P, IGLV5-62*01 P, IGLV5-60*01 P, IGLV5-57*01 P, IGLV5-54*01 P, IGLV1-53*01 P, IGLV1-52*01 P, IGLV5-45*01 P, IGLV5-43*01 P, IGLV1-39-1*01 P, IGLV1-39*01 P, IGLV1-36-1*01 P, IGLV1-33*01 P, IGLV1-32-2*01 P, IGLV5-32-1*01 P, IGLV5-31*01 P, IGLV5-29*01 P, IGLV5-28*01 P, IGLV7-27*01 P, IGLV7-25*01 P, IGLV7-24-2*01 P, IGLV2-24-1*01 P, IGLV3-22-1*01 P, IGLV3-22*01 P, IGLV3-21*01 P, IGLV3-20-1*01 P, IGLV2-19*01 P, IGLV4-18*01 P, IGLV3-16*01 P, IGLV3-14*01 P, IGLV3-13-1*01 P, IGLV3-12-1*01 P, IGLV3-12*01 P, IGLV3-9-1*01 P, IGLV3-9*01 P, IGLV3-8*01 P, IGLV3-3*01 P, IGLV3-1*01 P.
- Addition of 12 IGLJ genes and alleles (10 F and 2 ORF): IGLJ1*01 F, IGLJ2*01 F, IGLJ3*01 ORF, IGLJ4*01 F, IGLJ5*01 F, IGLJ6*01 F, IGLJ7*01 F, IGLJ8*01 F, IGLJ9*01 F, IGLJ10*01 F, IGLJ11*01 F, IGLJ12*01 ORF.
- Addition of 12 IGLC genes and alleles (5 F and 7 P): IGLC1*01 F, IGLC2*01 F, IGLC3*01 P, IGLC4P*01 P, IGLC4*01 F, IGLC5*01 F, IGLC6*01 P, IGLC7*01 P, IGLC8*01 P, IGLC9*01 F, IGLC10*01 P, IGLC11*01 P.
22 Fabruary 2019 - Update of Salmo salar (Atlantic Salmon) IGH reference directory:
- Addition of 26 IGHV genes and alleles (12 F, 5 ORF and 9 P):IGHV11-123*02 P, IGHV6-119*02 F, IGHV3-111*02 F, IGHV8-110*02 ORF, IGHV8S1*01 F, IGHV8-105*01 F, IGHV8-103*02 F, IGHV8-58*02 F, IGHV1S1*01 F, IGHV1-34*02 ORF, IGHV8-24*02 F IGHV5-16*02 ORF, IGHV6-38*02 P, IGHV1DS3*01 ORF, IGHV7DS1*01 P, IGHV3DS1*01 F, IGHV1DS1*01 F, IGHV1D-132*02 P, IGHV15D-38*02 P, IGHV1D-25*02 F, IGHV2D-12*02 P, IGHV4S1*01 ORF, IGHV1S3*01 P, IGHV1S2*01 P, IGHV4DS1*01 P, IGHV1DS2*01 F.
- Addition of 2 IGHJ genes and alleles (2 F): IGHJ5*02 F, IGHJ5D*02 F.
- Addition of 6 IGHC genes and alleles (6 F): IGHM*02 F, IGHM*03 (F), IGHMD*02 F, IGHD*02 F, IGHD*03 F, IGHDD*02 F.
18 Fabruary 2019 - Creation of the Sus scrofa (pig) TRB reference directory:
- Addition of 30 TRBV genes and alleles (27 F and 3 P): TRBV1*01 F, TRBV2-1*01 P, TRBV2-4*01 F, TRBV3*01 F, TRBV4-1*01 F, TRBV4-3*01 F, TRBV4-4*01 F, TRBV4-5*01 F, TRBV5-1*01 F, TRBV5-3*01 F, TRBV6*01 P, TRBV7-1*01 F, TRBV7-2*01 F, TRBV10*01 F, TRBV11*01 F, TRBV12-1*01 F, TRBV12-2*01 P, TRBV14*01 F, TRBV15*01 F, TRBV19*01 F, TRBV20-1*01 F, TRBV20-2*01 F, TRBV20-3*01 F, TRBV21*01 F, TRBV24*01 F, TRBV25*01 F, TRBV27*01 F, TRBV28*01 F, TRBV29*01 P, TRBV30*01 F.
- Addition of 3 TRBD genes and alleles (3 F): TRBD1*01 F, TRBD2*01 F and TRBD3*01 F.
- Addition of 20 TRBJ genes and alleles (20 F): TRBJ1-1*01 F, TRBJ1-2*01 F, TRBJ1-3*01 F, TRBJ1-4*01 F, TRBJ1-5*01 F, TRBJ1-6*01 F, TRBJ1-7*01 F, TRBJ3-1*01 F, TRBJ3-2*01 F, TRBJ3-3*01 F, TRBJ3-4*01 F, TRBJ3-5*01 F, TRBJ3-6*01 F, TRBJ3-7*01 F, TRBJ2-1*01 F, TRBJ2-2*01 F, TRBJ2-3*01 F, TRBJ2-4*01 F, TRBJ2-5*01 F, TRBJ2-6*01 F.
- Addition of 3 TRBC genes and alleles (3 F): TRBC1*01 F, TRBC2*01 F and TRBC3*01 F.
14 Fabruary 2019 - Creation of the Felis catus (cat) TRG reference directory:
- Addition of 12 TRGV genes and 12 alleles (5 F, 1 ORF and 6 P): TRGV2-1*01 F, TRGV2-2*01 F, TRGV2-3*01 F, TRGV2-4*01 F, TRGV5-1*01 P, TRGV5-2*01 P, TRGV5-3*01 ORF, TRGV5-4*01 P, TRGV6-1*01 P, TRGV7-1*01 F, TRGVA*01 P, TRGVB*01 P.
- Addition of 12 TRGJ genes and 12 alleles (4 F, 2 ORF and 6 P): TRGJ1-1*01 P TRGJ1-2*01 F, TRGJ2-1*01 P, TRGJ2-2*01 F, TRGJ2-3*01 P, TRGJ3-1*01 P, TRGJ3-2*01 F, TRGJ4-1*01 P, TRGJ5-1*01 ORF, TRGJ5-2*01 P, TRGJ6-1*01 ORF, TRGJ6-2*01 F.
- Addition of 6 TRGC genes and 6 alleles (4 F and 2 P): TRGC1*01 F, TRGC2*01 F, TRGC3*01 F, TRGC4*01 F, TRGC5*01 P, TRGC6*01 P.
24 January 2019
- Update of Homo spaiens (human) TRA reference directory: TRAJ35*01 functionnality is F.
14 January 2019
- Update of Salmo salar (saumon) IGH reference directory: IGHV1-21*01 functionnality is F.
- Update of Salmo salar (saumon) IGH reference directory: IGHV1-34*01 functionnality is ORF.
- Update of Salmo salar (saumon) IGH reference directory: IGHV4-56*01 functionnality is F.
- Update of Salmo salar (saumon) IGH reference directory: IGHV8-53*03 functionnality is F.
- Update of Salmo salar (saumon) IGH reference directory: IGHV1D-62*01 functionnality is F.
- Update of Salmo salar (saumon) IGH reference directory: IGHV4D-66*01 functionnality is F.
- Update of Salmo salar (saumon) IGH reference directory: IGHV1D-87*01 functionnality is F.
- Update of Salmo salar (saumon) IGH reference directory: IGHV4D-106*01 functionnality is F.
- Update of Salmo salar (saumon) IGH reference directory: IGHV1D-128 functionnality is F.
10 January 2019 - Creation of the Oryctolagus cuniculus (rabbit) TRB reference directory:
- Addition of 77 TRBV genes and 80 alleles (62 F and 18 P): TRBV1*01 F, TRBV2-1*01 F, TRBV2-2*01 P, TRBV2-2*02 F, TRBV3*01 F, TRBV3*02 F, TRBV4*01 F, TRBV4*02 F, TRBV5-1*01 F, TRBV5-2*01 F, TRBV5-3*01 P, TRBV5-4*01 F, TRBV5-5*01 F, TRBV5-6*01 P, TRBV5-7*01 F, TRBV5-8*01 F, TRBV5-9*01 F, TRBV5-10*01 F, TRBV5-11*01 P, TRBV5-12*01 F, TRBV5-13*01 P, TRBV5-14*01 F, TRBV5-15*01 F, TRBV5-16*01 F, TRBV5-17*01 F, TRBV6-1*01 P, TRBV6-2*01 F, TRBV6-3*01 F, TRBV6-4*01 F, TRBV6-5*01 F, TRBV6-6*01 F, TRBV6-7*01 F, TRBV6-8*01 F, TRBV6-9*01 F, TRBV6-10*01 F, TRBV6-11*01 F, TRBV6-12*01 F, TRBV6-13*01 F, TRBV6-14*01 F, TRBV7-1*01 F, TRBV7-2*01 F, TRBV7-3*01 F, TRBV7-4*01 P, TRBV7-5*01 F, TRBV7-6*01 P, TRBV7-7*01 F, TRBV7-8*01 P, TRBV7-9*01 P, TRBV7-10*01 F, TRBV7-11*01 F, TRBV7-12*01 P, TRBV7-13*01 F, TRBV7-14*01 F, TRBV9-1*01 P, TRBV9-2*01 P, TRBV10*01 F, TRBV12*01 F, TRBV13*01 F, TRBV15*01 P, TRBV16*01 P, TRBV17*01 P, TRBV18*01 F, TRBV19*01 F, TRBV20-1*01 F, TRBV20-2*01 F, TRBV21-1*01 F, TRBV21-2*01 F, TRBV21-3*01 F, TRBV21-4*01 F, TRBV21-5*01 F, TRBV21-6*01 F, TRBV21-7*01 F, TRBV23*01 P, TRBV24*01 P, TRBV25*01 F, TRBV26*01 F, TRBV27*01 F, TRBV28*01 F, TRBV29*01 F, TRBV30*01 F.
- Addition of 2 TRBD genes and 2 alleles (2 F): TRBD1*01 F, TRBD2*01 F.
- Addition of 12 TRBJ genes and 13 alleles (12 F and 1 ORF): TRBJ1-1*01 F, TRBJ1-2*01 F, TRBJ1-3*01 F, TRBJ1-4*01 F, TRBJ1-5*01 ORF, TRBJ1-6*01 F, TRBJ2-1*01 F, TRBJ2-2*01 F, TRBJ2-3*01 F, TRBJ2-4*01 F, TRBJ2-5*01 F, TRBJ2-6*01 F, TRBJ2-6*02 F.
- Addition of 2 TRBC genes and 5 alleles (5 F): TRBC1*01 F, TRBC1*02 F, TRBC1*03 F, TRBC1*04 F, TRBC2*01 F.
08 January 2019 - Update of Homo sapiens (human) IGHC reference directory:
- Addition of 27 IGHC genes and alleles (27 F):
  9 new alleles of the Homo sapiens IGHG1 gene: IGHG1*06, IGHG1*07, IGHG1*08, IGHG1*09, IGHG1*10, IGHG1*11, IGHG1*12, IGHG1*13, IGHG1*14
  9 new alleles of the Homo sapiens IGHG2 gene: IGHG2*07, IGHG2*08, IGHG2*09, IGHG2*10, IGHG2*11, IGHG2*12, IGHG2*13, IGHG2*14, IGHG2*15
  9 new alleles of the Homo sapiens IGHG3 gene: IGHG3*21, IGHG3*22, IGHG3*23, IGHG3*24, IGHG3*25, IGHG3*26, IGHG3*27, IGHG3*28, IGHG3*29
19 December 2018
- Update of Macaca mulatta (rhesus monkey) TRB reference directory: TRBV12-1*01 functionnality is ORF.
18 December 2018
- Update of Macaca mulatta (rhesus monkey) TRA/TRD reference directory: TRAJ61*01 functionnality is ORF.
- Update of Macaca mulatta (rhesus monkey) TRA/TRD reference directory: TRAJ51*01 functionnality is ORF.
17 December 2018
- Update of Mustela putorius furo (ferret) TRB reference directory : TRBV6*01 functionnality is ORF.
- Update of Oryctolagus cuniculus (rabbit) TRA/TRD reference directory: TRAJ61*01 functionnality is ORF.
- Update of Oryctolagus cuniculus (rabbit) TRA/TRD reference directory: TRAJ51*01 functionnality is ORF.
10 December 2018 - Update of Macaca mulatta (rhesus monkey) TRB reference directory:
- Update of TRBV6-5*01, TRBV7-1*01, TRBV7-7-1*01 reference sequences and sequences from literature.

04 December 2018

Update of Vicugna pacos (Alpaca) IGHV nomenclature:

IGHV gene old name	IGHV gene new name
IGHV2S1*01	IGHV4S1
IGHV2S2*01	IGHV4S2
IGHV2S3*01	IGHV4S3
IGHV2S4*01	IGHV4S4
IGHV2S5*01	IGHV4S5
IGHV2S6*01	IGHV4S6
IGHV2S7*01	IGHV4S7
IGHV2S8*01	IGHV4S8
IGHV2S9*01	IGHV4S9
IGHV2S10*01	IGHV4S10
IGHV2S11*01	IGHV4S11

30 November 2018
- Update of the IMGT numbering for Canis lupus familiaris (dog) TRBV1*01.
- Update of the IMGT numbering for Mustela putorius furo (ferret) TRBV1*01.
23 November 2018
- Update of Macaca mulatta (rhesus monkey) TRB reference directory: TRBV10-2*01 functionnality is F.
- Update of Macaca mulatta (rhesus monkey) TRB reference directory: TRBV13*01 functionnality is F.
21 November 2018
- Update of the IMGT numbering for Canis lupus familiaris (dog) TRAC*01.
- Update of the IMGT numbering for Tursiops truncatus (Bottlenose dolphin) TRAC*01.
- Update of the IMGT numbering for Bos taurus (bovine) TRDC*01.
- Update of the IMGT numbering for Canis lupus familiaris (dog) TRDC*01.
- Update of the IMGT numbering for Danio rerio (zebrafish) TRDC*01.
- Update of the IMGT numbering for Homo sapiens (human) TRDC*01.
- Update of the IMGT numbering for Macaca mulatta (Rhesus monkey) TRDC*01 and TRDC*02.
- Update of the IMGT numbering for Oryctolagus cuniculus (rabbit) TRDC*01.
- Update of the IMGT numbering for Ovis aries (sheep) TRDC*01.
- Update of the IMGT numbering for Tursiops truncatus (Bottlenose dolphin) TRDC*01.
20 November 2018
- Update of the IMGT numbering for Bos taurus (bovine) TRAC*01.
- Update of the IMGT numbering for Bos taurus (bovine) TRDC*01.
- Update of the IMGT numbering for Canis lupus familiaris (dog) TRAC*01.
- Update of the IMGT numbering for Ovis aries (sheep) TRAC*01.
- Update of the IMGT numbering for Ovis aries (sheep) TRDC*01.
09 November 2018
- Creation of the Oryctolagus cuniculus (rabbit) TRA/TRD reference directory:
  - Addition of 61 TRAV genes and 61 alleles (48 F, 2 ORF and 11 P): TRAV4*01 F, TRAV5-1*01 P, TRAV5-10*01 F, TRAV5-2*01 F, TRAV5-3*01 F, TRAV5-4*01 F, TRAV5-5*01 F, TRAV5-6*01 P, TRAV5-7*01 F, TRAV5-8*01 F, TRAV5-9*01 F, TRAV8-1*01 F, TRAV8-2*01 F, TRAV8-3*01 F, TRAV8-4*01 F, TRAV8-5*01 F, TRAV9-1*01 F, TRAV9-2*01 F, TRAV9-3*01 F, TRAV9-4*01 F, TRAV10*01 F, TRAV12*01 F, TRAV13-1*01 P, TRAV13-2*01 F, TRAV13-3*01 F, TRAV13-4*01 F, TRAV14-1*01 F, TRAV14-2*01 F, TRAV16*01 F, TRAV17*01 F, TRAV18*01 F, TRAV19*01 F, TRAV20*01 P, TRAV21*01 P, TRAV23*01 F, TRAV24*01 F, TRAV26*01 F, TRAV27*01 P, TRAV28*01 P, TRAV29*01 P, TRAV32*01 F, TRAV35*01 P, TRAV36*01 P, TRAV37*01 F, TRAV38-1*01 F, TRAV38-2*01 F, TRAV39*01 F, TRAV41*01 F, TRAV42*01 F, TRAV43-1*01 ORF, TRAV43-2*01 ORF, TRAV43-3*01 F, TRAV43-4*01 F, TRAV43-5*01 F, TRAV44-1*01 P, TRAV44-2*01 F, TRAV44-3*01 F, TRAV44-4*01 F, TRAV44-5*01 F, TRAV44-6*01 F, TRAV45*01 F.
  - Addition of 58 TRAJ genes and 58 alleles (49 F, 6 ORF and 3 P): TRAJ1*01 ORF, TRAJ2*01 F, TRAJ3*01 F, TRAJ4*01 F, TRAJ5*01 ORF, TRAJ6*01 F, TRAJ7*01 F, TRAJ8*01 F, TRAJ9*01 F, TRAJ10*01 ORF, TRAJ11*01 F, TRAJ12*01 F, TRAJ13*01 F, TRAJ14*01 ORF, TRAJ15*01 F, TRAJ16*01 F, TRAJ17*01 F, TRAJ18*01 F, TRAJ19*01 ORF, TRAJ20*01 F, TRAJ21*01 F, TRAJ22*01 F, TRAJ23*01 F, TRAJ24*01 F, TRAJ25*01 F, TRAJ26*01 F, TRAJ27*01 F, TRAJ28*01 F, TRAJ29*01 F, TRAJ30*01 ORF, TRAJ31*01 F, TRAJ32*01 F, TRAJ33*01 F, TRAJ34*01 F, TRAJ35*01 F, TRAJ36*01 F, TRAJ37*01 F, TRAJ38*01 F, TRAJ39*01 F, TRAJ40*01 F, TRAJ41*01 F, TRAJ42*01 F, TRAJ43*01 F, TRAJ44*01 F, TRAJ45*01 F, TRAJ46*01 P, TRAJ47*01 F, TRAJ48*01 F, TRAJ49*01 F, TRAJ50*01 F, TRAJ51*01 P, TRAJ52*01 F, TRAJ53*01 F, TRAJ54*01 F, TRAJ56*01 F, TRAJ57*01 F, TRAJ58*01 F, TRAJ61*01 P.
  - Addition of 1 TRAC genes and 1 alleles (1 F): TRAC*01 F.
  - Addition of 4 TRDV genes and 4 alleles (3 F and 1 P): TRDV1*01 F, TRDV2*01 F, TRDV3*01 F, TRDV4*01 P.
  - Addition of 2 TRDD genes and 2 alleles (2 F): TRDD1*01 F, TRDD2*01 F.
  - Addition of 3 TRDJ genes and 3 alleles (2 F and 1 P): TRDJ1*01 P, TRDJ2*01 F, TRDJ3*01 F.
  - Addition of 1 TRDC genes and 1 alleles (1 F): TRDC*01 F.
- Update of the IMGT numbering for Tursiops truncatus (Bottlenose dolphin) TRAC*01.
31 October 2018 - Update of Macaca mulatta (Rhesus monkey) TRA/TRD reference directory :
- TRAV1-1*01 functionality is F.
- TRAV1-2*01 functionality is F.
- TRAV25*01 functionality is F.
- TRAV34*01 functionality is F.
- TRAV11-2*01 functionality is ORF.
- TRAJ2*01 functionality is F.
- TRAJ58*01 functionality is F.
- TRDV3*01 functionality is F.
- Update of the Macaca mulatta (Rhesus monkey) TRDJ gene nomenclature:
  
  TRDJ gene old name TRDJ gene new name
  
  TRDJ2*01 TRDJ4*01
  
  TRDJ3*01 TRDJ2*01
  
  TRDJ4*01 TRDJ3*01
- TRDV3*02 functionality is F.
- Update of TRAJ61*01 reference sequences
- Addition of the TRAJ61*01 (P), TRAJ60*01 (F), TRAJ59*01 (P), TRAJ58*01 (F), TRAJ57*01 (F), TRAJ56*01 (F), TRAJ55*01 (P), TRAJ54*01 (F), TRAJ53*01 (F), TRAJ51*01 (P), TRDJ1*01 (F), TRDJ2*01 (F), TRDJ3*01 (F),TRDJ4*01 (F), TRDD1*01 (ORF), TRDD2*01 (F), TRDD3*01 (F), TRDD4*01 (F), TRDV2*01 (F), TRDV4*01 (F), sequences from literature.
29 October 2018 - Creation of the Salmo salar (Atlantic salmon) IGH reference directory :
- Addition of 291 IGHV genes and 291 alleles (55 F, 10 ORF and 226 P): IGHV1-10*01 P, IGHV1-100*01 F, IGHV1-104*01 P, IGHV1-117*01 F, IGHV1-118*01 P, IGHV1-122*01 P, IGHV1-18-1*01 P, IGHV1-2*01 P, IGHV1-21*01 P, IGHV1-25*01 P, IGHV1-25-1*01 P, IGHV1-30*01 P, IGHV1-34*01 P, IGHV1-36*01 P, IGHV1-40*01 P, IGHV1-42*01 P, IGHV1-47*01 P, IGHV1-5*01 P, IGHV1-52*01 P, IGHV1-54*01 P, IGHV1-55*01 P, IGHV1-62*01 P, IGHV1-64*01 F, IGHV1-70*01 P, IGHV1-73*01 F, IGHV1-79-1*01 F, IGHV1-87*01 P, IGHV1-96*01 P, IGHV1-98*01 P, IGHV10-102*01 P, IGHV10-107*01 P, IGHV10-109*01 P, IGHV10-116*01 P, IGHV10-27*01 P, IGHV10-29*01 P, IGHV10-32*01 P, IGHV10-41*01 P, IGHV10-43*01 P, IGHV10-48*01 P, IGHV10-57*01 P, IGHV10-65*01 P, IGHV10-79*01 P, IGHV10-89*01 P, IGHV10D-112*01 P, IGHV10D-120*01 P, IGHV10D-124*01 P, IGHV10D-36*01 P, IGHV10D-56*01 ORF, IGHV10D-58*01 P, IGHV10D-72*01 P, IGHV10D-80*01 P, IGHV10D-84*01 P, IGHV11-108*01 P, IGHV11-113*01 F, IGHV11-118-1*01 P, IGHV11-123*01 P, IGHV11-24-1*01 P, IGHV11-33*01 P, IGHV11-39*01 P, IGHV11-46*01 F, IGHV11D-115*01 P, IGHV11D-140*01 P, IGHV11D-142*01 P, IGHV11D-144*01 P, IGHV11D-75*01 P, IGHV11D-98*01 P, IGHV12-112*01 P, IGHV12D-50*01 F, IGHV12D-6*01 ORF, IGHV13-20*01 P, IGHV13D-122*01 P, IGHV13D-82*01 P, IGHV14-51*01 P, IGHV14D-102*01 P, IGHV15-120*01 P, IGHV15-124*01 F, IGHV15-26*01 P, IGHV15-7*01 P, IGHV15-71*01 P, IGHV15-8*01 P, IGHV15D-126*01 F, IGHV15D-22*01 P, IGHV15D-38*01 P, IGHV15D-60*01 P, IGHV15D-85*01 F, IGHV16-110-1*01 P, IGHV16-121*01 P, IGHV16-121-1*01 P, IGHV16-15*01 P, IGHV16-18*01 P, IGHV16-23*01 F, IGHV16-80*01 P, IGHV16-83*01 P, IGHV16D-116*01 F, IGHV16D-125*01 P, IGHV16D-127*01 P, IGHV16D-13*01 P, IGHV16D-130*01 P, IGHV16D-143*01 P, IGHV16D-23*01 F, IGHV16D-42*01 F, IGHV16D-59*01 P, IGHV16D-61*01 ORF, IGHV16D-64*01 P, IGHV16D-65*01 F, IGHV16D-76*01 F, IGHV16D-86*01 P, IGHV16D-89*01 P, IGHV1D-101*01 P, IGHV1D-106-1*01 P, IGHV1D-108*01 F, IGHV1D-114*01 P, IGHV1D-121*01 P, IGHV1D-128*01 P, IGHV1D-132*01 P, IGHV1D-134*01 P, IGHV1D-136*01 F, IGHV1D-139*01 ORF, IGHV1D-14*01 F, IGHV1D-25*01 F, IGHV1D-3*01 P, IGHV1D-32*01 P, IGHV1D-34*01 F, IGHV1D-4*01 P, IGHV1D-44-3*01 P, IGHV1D-49*01 P, IGHV1D-49-1*01 P, IGHV1D-5*01 P, IGHV1D-50-1*01 P, IGHV1D-55*01 P, IGHV1D-57*01 P, IGHV1D-62*01 P, IGHV1D-67*01 P, IGHV1D-69*01 F, IGHV1D-7-2*01 P, IGHV1D-74*01 P, IGHV1D-81*01 P, IGHV1D-87*01 P, IGHV1D-91*01 P, IGHV1D-93*01 P, IGHV1D-97*01 F, IGHV2-60*01 F, IGHV2-92*01 F, IGHV2D-12*01 F, IGHV2D-129*01 P, IGHV2D-146*01 P, IGHV2D-30*01 F, IGHV2D-39*01 F, IGHV2D-40*01 P, IGHV2D-63*01 P, IGHV2D-88*01 P, IGHV3-11-1*01 P, IGHV3-111*01 F, IGHV3-61*01 P, IGHV3-86-1*01 P, IGHV3-93*01 P, IGHV3D-105-1*01 P, IGHV3D-47*01 P, IGHV3D-54*01 P, IGHV3D-7*01 P, IGHV3D-9*01 P, IGHV4-1*01 P, IGHV4-105-1*01 P, IGHV4-13*01 ORF, IGHV4-17*01 P, IGHV4-4*01 P, IGHV4-56*01 P, IGHV4-71-1*01 P, IGHV4-72*01 P, IGHV4-75*01 P, IGHV4-81*01 P, IGHV4-85*01 P, IGHV4-88*01 P, IGHV4-9*01 P, IGHV4-94*01 P, IGHV4-97*01 F, IGHV4D-1*01 P, IGHV4D-100*01 ORF, IGHV4D-106*01 P, IGHV4D-133*01 P, IGHV4D-135*01 P, IGHV4D-141*01 P, IGHV4D-145*01 P, IGHV4D-23-1*01 P, IGHV4D-33*01 P, IGHV4D-43*01 P, IGHV4D-44-1*01 P, IGHV4D-51*01 F, IGHV4D-66*01 P, IGHV4D-7-1*01 P, IGHV4D-8-1*01 P, IGHV4D-92*01 P, IGHV4D-94*01 P, IGHV5-14*01 P, IGHV5-16*01 ORF, IGHV5-82*01 ORF, IGHV5-84*01 P, IGHV5D-131*01 P, IGHV5D-31*01 P, IGHV5D-44*01 P, IGHV5D-90*01 P, IGHV6-101*01 P, IGHV6-108-1*01 P, IGHV6-114*01 P, IGHV6-119*01 F, IGHV6-19*01 P, IGHV6-22*01 P, IGHV6-31*01 P, IGHV6-35*01 P, IGHV6-38*01 P, IGHV6-45*01 P, IGHV6-50*01 P, IGHV6-59*01 P, IGHV6-63*01 P, IGHV6-64-1*01 P, IGHV6-68*01 ORF, IGHV6-77*01 P, IGHV6-91*01 P, IGHV6-99*01 P, IGHV6D-107*01 P, IGHV6D-109*02 P, IGHV6D-11*01 P, IGHV6D-113*01 P, IGHV6D-117*01 P, IGHV6D-118*01 F, IGHV6D-119*01 P, IGHV6D-137*01 F, IGHV6D-16*01 F, IGHV6D-17*01 P, IGHV6D-18*01 F, IGHV6D-19*01 P, IGHV6D-2*01 P, IGHV6D-20*01 P, IGHV6D-21*01 P, IGHV6D-24*01 P, IGHV6D-26*01 P, IGHV6D-27*01 P, IGHV6D-41*01 P, IGHV6D-68*01 P, IGHV6D-70*01 P, IGHV6D-73*01 P, IGHV6D-77*01 P, IGHV6D-78*01 F, IGHV6D-79*01 P, IGHV6D-95*01 F, IGHV7-3*01 P, IGHV7-74*01 P, IGHV7-95*01 F, IGHV7D-15*01 P, IGHV7D-8*01 P, IGHV8-103*01 F, IGHV8-105*02 F, IGHV8-106*01 P, IGHV8-110*01 ORF, IGHV8-114-1*01 P, IGHV8-115*01 P, IGHV8-18-2*01 P, IGHV8-24*01 F, IGHV8-28*01 F, IGHV8-37*01 F, IGHV8-44*01 P, IGHV8-44-1*01 P, IGHV8-49*01 F, IGHV8-53*03 P, IGHV8-58*01 P, IGHV8-66*01 F, IGHV8-67*01 F, IGHV8-69*01 P, IGHV8-78*01 P, IGHV8-90*01 P, IGHV8D-110*01 P, IGHV8D-123*01 F, IGHV8D-138*01 P, IGHV8D-28*01 P, IGHV8D-48*01 F, IGHV8D-71*01 P, IGHV8D-83*01 F, IGHV8D-96*01 P, IGHV9-11*01 P, IGHV9-12*01 P, IGHV9-6*01 P, IGHV9-76*01 F, IGHV9-86*01 P, IGHV9D-103*01 F, IGHV9D-104*01 F, IGHV9D-105*01 P, IGHV9D-44-2*01 P, IGHV9D-45*01 F, IGHV9D-46*01 P, IGHV9D-52*01 P, IGHV9D-53*01 P.
- Addition of 21 IGHJ genes and alleles (18 F, 1 ORF and 2 P): IGHJ1*01 F, IGHJ1D*01 F, IGHJ1T1D*01 P, IGHJ1T2*01 F, IGHJ1T2D*01 F, IGHJ1T3*01 F, IGHJ1T4*01 F, IGHJ1T5*01 P, IGHJ2*01 ORF, IGHJ2D*01 F, IGHJ2T2*01 F, IGHJ2T2D*01 F, IGHJ2T3*01 F, IGHJ2T4*01 F, IGHJ2T5*01 F, IGHJ3*01 F, IGHJ3D*01 F, IGHJ4*01 F, IGHJ4D*01 F, IGHJ5*01 F, IGHJ5D*01 F.
- Addition of 28 IGHD genes and 28 alleles (26 F and 2 ORF): IGHD1*01 ORF, IGHD1D*01 F, IGHD1T2*01 F, IGHD1T2D*01 F, IGHD1T3D*01 F, IGHD1T4*01 F, IGHD1T5*01 F, IGHD2*01 F, IGHD2D*01 F, IGHD2T2*01 F, IGHD2T2D*01 F, IGHD2T3D*01 F, IGHD2T4*01 F, IGHD3*01 F, IGHD3D*01 F, IGHD3T3D*01 F, IGHD3T4*01 F, IGHD4*01 F, IGHD4D*01 F, IGHD4T4*01 F, IGHD5*01 ORF, IGHD5D*01 F, IGHD5T4*01 F, IGHD6*01 F, IGHD6D*01 F, IGHD7*01 F, IGHD8*01 F, IGHD9*01 F.
- Addition of 12 IGHC genes and 12 alleles (6 F and 6 P): IGHD*01 F, IGHDD*01 F, IGHM*01 F, IGHMD*01 F, IGHT1*01 P, IGHT1D*01 P, IGHT2*01 P, IGHT2D*01 F, IGHT3*01 P, IGHT3D*01 P, IGHT4*01 F, IGHT5*01 P.
25 October 2018 - Update of Tursiops truncatus (Bottlenose dolphin) TRA/TRD reference directory:
- TRAJ2*01 functionality is F.
- TRDJ2*01 functionality is ORF.
04 October 2018 - Update of the Homo sapiens (human) IGHV reference directory:
- Addition of the IGHIGHV3-42D*04 (P), IGHV3-43D*04 (F), IGHV(II)-43-1D*02 (P) reference sequences.
03 October 2018 - Creation of the Oryctolagus cuniculus (rabbit) TRG reference directory:
- Addition of 11 TRGV genes and 25 alleles (21 F and 4 ORF) : TRGV1-1*01 F, TRGV1-1*02 F, TRGV1-1*03 F, TRGV1-2*01 F, TRGV1-3*01 F, TRGV1-3*02 F, TRGV1-3*03 F, TRGV1-3*04 F, TRGV1-3*05 F, TRGV1-3*06 F, TRGV1-3*07 F, TRGV1-3*08 F, TRGV1-4*01 F, TRGV1-4*02 F, TRGV1-4*03 F, TRGV1-5*01 F, TRGV1-5*02 F, TRGV1-6*01 F, TRGV1-6*02 F, TRGV1-7*01 ORF, TRGV1-7*02 ORF, TRGV2*01 ORF, TRGV3*01 F, TRGV4*01 ORF, TRGV1-2D*01 F
- Addition of 2 TRGJ genes and alleles (2 F): TRGJ1*01 F, TRGJ2*01 F.
- Addition of TRGC*01 F.
26 September 2018 - Update of the Homo sapiens (human) IGHV reference directory:
- Update of IGHV3-43D allele name: Previous IGHV3-43D*01 has been assigned to IGHV3-43D*03.
20 September 2018 - Update of the Homo sapiens (human) TRAJ reference directory:
- Update of TRAJ31*01 reference sequences.
12 September 2018
- Creation of the Mustela putorius furo (ferret) TRB reference directory:
  - Addition of 34 TRBV genes and 34 alleles (20 F, 2 ORF and 12 P): TRBV1*01 ORF, TRBV2*01 P, TRBV3*01 F, TRBV4-1*01 F, TRBV4-2*01 F, TRBV5-1*01 P, TRBV5-2*01 F, TRBV5-3*01 P, TRBV5-4*01 F, TRBV6*01 P, TRBV7-1*01 F, TRBV7-2*01 F, TRBV8*01 F, TRBV10*01 P, TRBV11*01 P, TRBV12-1*01 F, TRBV12-2*01 F, TRBV15*01 F, TRBV16*01 F, TRBV17*01 P, TRBV18*01 F, TRBV19*01 F, TRBV20*01 ORF, TRBV21*01 F, TRBV22*01 F, TRBV23*01 P, TRBV24*01 P, TRBV25*01 F, TRBV26*01 F, TRBV27*01 F, TRBV28*01 P, TRBV29*01 F, TRBV30*01 P, TRBVA*01 P.
  - Addition of 2 TRBD genes and 2 alleles (2 F): TRBD1*01 F, TRBD2*01 F.
  - Addition of 12 TRBJ genes and 12 alleles (7 F, 4 ORF and 1 P): TRBJ1-1*01 ORF, TRBJ1-2*01 F, TRBJ1-3*01 P, TRBJ1-4*01 ORF, TRBJ1-5*01 F, TRBJ1-6*01 F, TRBJ2-1*01 ORF, TRBJ2-2*01 F, TRBJ2-3*01 F, TRBJ2-4*01 F, TRBJ2-5*01 ORF, TRBJ2-6*01 F.
  - Addition of 2 TRBC genes and 2 alleles (2 F): TRBC1*01 F, TRBC2*01 F.
- Update of the Macaca mulatta (Rhesus monkey) TRA/TRD reference directory:
  - Addition of TRAJ52*02 F.
  - Addition of TRDV3*02 ORF.
  - Addition of TRDC*02 F.
11 September 2018 - Update of the Macaca mulatta (Rhesus monkey) TRBV reference directory:
- Addition of 77 TRBV genes and alleles : TRBV1-1*01 P, TRBV2-1*01 F, TRBV3-1*01 F, TRBV4-1*01 F, TRBV1-2*01 P, TRBV2-2*01 F, TRBV3-2*01 F, TRBV1-3*01 P, TRBV2-3*01 F, TRBV3-3*01 F, TRBV4-2*01 F, TRBV7-1*01 P, TRBV3-4*01 F, TRBV6-2-1*01 F, TRBV7-3*01 F, TRBV8-2*01 P, TRBV11-1*01 F, TRBV10-2*01 ORF, TRBV11-2*01 F, TRBV12-1*01 P, TRBV7-5*01 F, TRBV6-5*01 ORF, TRBV7-6*01 F, TRBV5-6*01 F, TRBV7-7*01 F, TRBV5-7*01 F, TRBV6-6*01 F, TRBV7-7-1*01 P, TRBV5-8*01 F, TRBV6-7*01 ORF, TRBV7-8*01 P, TRBV6-8*01 ORF, TRBV7-9*01 F, TRBV5-10*01 F, TRBV7-10*01 ORF, TRBV13*01 P, TRBV11-3*01 F, TRBV12-3*01 F, TRBV12-4*01 F, TRBV14*01 F, TRBV15*01 F, TRBV16*01 F, TRBV18*01 F, TRBV19*01 F, TRBV20-1*01 F, TRBV21-1*01 F, TRBV22-1*01 P, TRBV23-1*01 F, TRBV24-1*01 F, TRBV25-1*01 F, TRBVA*01 P, TRBV26*01 P, TRBVB*01 P, TRBV27*01 F, TRBVC*01 P, TRBV28*01 F, TRBV29-1*01 F, TRBV30*01 F, TRBV5-1*02 P, TRBV6-1*02 F, TRBV4-3*02 F, TRBV5-2*02 P, TRBV6-2*02 F, TRBV5-3*02 ORF, TRBV9*02 F, TRBV10-1*02 F, TRBV6-3*02 F, TRBV7-4*02 F, TRBV5-4*02 P, TRBV6-4*02 P, TRBV5-9*02 F, TRBV10-3*02 F, TRBV12-2*02 F, TRBV6-5-1*02 P, TRBV7-2*02 P, TRBV8-1*02 P.
10 September 2018
- Update of the Macaca mulatta (Rhesus monkey) TRBV reference directory:
  - TRBV10-2*01 functionality is ORF.
  - TRBV5-5*01 functionality is P.
  - TRBV6-7*01 functionality is ORF.
  - TRBV6-8*01 functionality is ORF.
  - TRBV7-10*01 functionality is ORF.
  - TRBV13*01 functionality is P.
  - TRBV12-1*01 functionality is P.
  - TRBV6-5*01 functionality is ORF.
- Update of the Homo sapiens (human) TRBV reference directory:
  - Addition of gapped IMGT reference sequence for TRBV30*03 P (IMGT/LIGM-DB accession number IMGT000027).
31 August 2018 - Update of the Homo sapiens (human) IGHC reference directory:
- Addition of the IGHE*03 CH1, CH2, CH3, and CH4-CHS reference sequences.
30 August 2018 - Creation of the Tursiops truncatus (Bottlenose dolphin) TRA/TRD reference directory:
- Addition of 18 TRAV genes and 23 alleles (15 F, 2 ORF and 6 P): TRAV8-1*01 F, TRAV8-1D*01 F, TRAV9*01 F, TRAV14*01 F, TRAV16*01 F, TRAV17*01 F, TRAV18-1*01 F, TRAV19*01 P, TRAV20-1*01 F, TRAV20-1D*01 F, TRAV24*01 P, TRAV24D*01 P, TRAV37*01 ORF, TRAV38-1*01 F, TRAV38-2*01 P, TRAV39*01 P, TRAV40*01 P, TRAV41*01 F, TRAV9*02 F, TRAV14*02 F, TRAV16*02 F, TRAV17*02 F, TRAV37*02 ORF.
- Addition of 60 TRAJ genes and 60 alleles (44 F, 13 ORF and 3 P): TRAJ1*01 ORF, TRAJ2*01 ORF, TRAJ3*01 F, TRAJ4*01 F, TRAJ5*01 F, TRAJ6*01 F, TRAJ7*01 F, TRAJ8*01 F, TRAJ9*01 F, TRAJ10*01 F, TRAJ11*01 F, TRAJ12*01 F, TRAJ13*01 F, TRAJ14*01 ORF, TRAJ15*01 F, TRAJ16*01 F, TRAJ17*01 F, TRAJ18*01 F, TRAJ19*01 ORF, TRAJ20*01 F, TRAJ21*01 F, TRAJ22*01 F, TRAJ23*01 ORF, TRAJ24*01 F, TRAJ25*01 ORF, TRAJ26*01 F, TRAJ27*01 F, TRAJ29*01 F, TRAJ30*01 F, TRAJ31*01 F, TRAJ32*01 F, TRAJ33*01 ORF, TRAJ34*01 F, TRAJ35*01 F, TRAJ36*01 ORF, TRAJ37*01 ORF, TRAJ38*01 F, TRAJ39*01 F, TRAJ40*01 F, TRAJ41*01 F, TRAJ42*01 ORF, TRAJ43*01 F, TRAJ44*01 F, TRAJ45*01 F, TRAJ46*01 ORF, TRAJ47*01 F, TRAJ48*01 F, TRAJ49*01 F, TRAJ50*01 F, TRAJ51*01 F, TRAJ52*01 F, TRAJ53*01 F, TRAJ54*01 F, TRAJ55*01 P, TRAJ56*01 P, TRAJ57*01 P, TRAJ58*01 F, TRAJ59*01 ORF, TRAJ60*01 F, TRAJ61*01 ORF.
- Addition of TRAC*01 F.
- Addition of 6 TRDV genes and 6 alleles (4 F and 2 P): TRDV1-1*01 F, TRDV1-1D*01 F, TRDV1-1N*01 F, TRDV2*01 F, TRDV4*01 P, TRDV5*01 P.
- Addition of 2 TRDD genes and 2 alleles (2 F): TRDD1S1*01 F, TRDD2S1*01 F.
- Addition of 4 TRDJ genes and 4 alleles (2 F, 1 ORF and 1 P): TRDJ1*01 ORF, TRDJ4*01 F, TRDJ2*01 F, TRDJ3*01 P.
- Addition of TRDC*01 F.
28 August 2018 - Update of the Macaca mulatta (Rhesus monkey) TRDJ reference directory:
- Update of the Macaca mulatta (Rhesus monkey) TRDJ gene nomenclature:
  
  TRDJ gene old name TRDJ gene new name
  
  TRDJ2*01 TRDJ4*01
  
  TRDJ3*01 TRDJ2*01
  
  TRDJ4*01 TRDJ3*01
27 August 2018 - Update of the Homo sapiens (human) TRAJ reference directory:
- Update of TRAJ59*01 reference sequence.
20 August 2018 - Update of the Homo sapiens (human) TRBV reference directory:
- Addition of 6 TRBV genes and alleles (4 F, 1 ORF, 1 in-frame P): TRBV10-2*03 F, TRBV11-2*04 F, TRBV15*04 F, TRBV17*02 ORF, TRBV21-1*02 P, TRBV24-1*02 F.
- Addition of 4 TRBV out-of-frame P genes and alleles: TRBVA*02 P, TRBVB*02 P, TRBV8-2*02 P, TRBV8-1*02 P.
- Addition of 2 TRBC genes and alleles (2F): TRBC1*03 and TRBC2*03.
9 August 2018 - Creation of the Canis lupus familiaris (Dog) IGL reference directory:
- Addition of 261 IGLV genes and 261 alleles (70 F, 15 ORF and 176 P): IGLV1-100*01 F, IGLV1-100-1*01 P, IGLV1-101*01 P, IGLV1-103*01 F, IGLV1-104*01 P, IGLV1-106*01 F, IGLV1-107*01 P, IGLV1-110*01 P, IGLV1-111*01 ORF, IGLV1-112*01 P, IGLV1-113-1*01 P, IGLV1-114*01 P, IGLV1-115*01 P, IGLV1-116*01 F, IGLV1-118*01 P, IGLV1-118-2*01 P, IGLV1-122*01 P, IGLV1-123*01 P, IGLV1-125*01 F, IGLV1-127*01 P, IGLV1-129*01 P, IGLV1-130*01 P, IGLV1-132*01 ORF, IGLV1-133*01 P, IGLV1-135*01 F, IGLV1-136*01 F, IGLV1-138*01 F, IGLV1-139*01 F, IGLV1-140*01 P, IGLV1-140-1*01 P, IGLV1-141*01 F, IGLV1-143*01 P, IGLV1-144*01 F, IGLV1-146*01 P, IGLV1-147*01 F, IGLV1-149*01 F, IGLV1-150*01 F, IGLV1-151*01 F, IGLV1-151-1*01 P, IGLV1-152*01 P, IGLV1-154*01 P, IGLV1-155*01 F, IGLV1-157*01 F, IGLV1-158*01 F, IGLV1-159*01 F, IGLV1-160*01 P, IGLV1-161-1*01 P, IGLV1-162*01 F, IGLV1-35*01 P, IGLV1-37*01 ORF, IGLV1-41*01 ORF, IGLV1-44*01 F, IGLV1-45*01 P, IGLV1-46*01 F, IGLV1-48*01 F, IGLV1-49*01 F, IGLV1-50*01 P, IGLV1-52*01 P, IGLV1-54*01 P, IGLV1-55*01 F, IGLV1-56*01 ORF, IGLV1-57*01 F, IGLV1-58*01 F, IGLV1-61*01 P, IGLV1-63*01 P, IGLV1-65*01 P, IGLV1-66*01 F, IGLV1-67*01 F, IGLV1-68*01 P, IGLV1-69*01 P, IGLV1-69-1*01 P, IGLV1-70*01 F, IGLV1-72*01 ORF, IGLV1-73*01 F, IGLV1-74*01 P, IGLV1-75*01 F, IGLV1-78*01 P, IGLV1-79*01 P, IGLV1-79-1*01 P, IGLV1-80*01 F, IGLV1-81*01 P, IGLV1-82*01 F, IGLV1-82-1*01 P, IGLV1-83*01 P, IGLV1-84*01 F, IGLV1-84-1*01 ORF, IGLV1-86*01 ORF, IGLV1-87*01 F, IGLV1-88*01 P, IGLV1-88-2*01 P, IGLV1-88-3*01 P, IGLV1-89*01 P, IGLV1-89-2*01 P, IGLV1-91*01 P, IGLV1-92*01 F, IGLV1-94*01 F, IGLV1-95-1*01 P, IGLV1-96*01 F, IGLV1-97*01 P, IGLV1-97-4*01 F, IGLV1-98*01 P, IGLV2-31*01 F, IGLV2-31-1*01 P, IGLV2-32*01 P, IGLV2-32-1*01 P, IGLV3-1*01 P, IGLV3-1-1*01 P, IGLV3-11*01 F, IGLV3-13*01 P, IGLV3-13-1*01 P, IGLV3-14*01 F, IGLV3-15*01 P, IGLV3-18*01 P, IGLV3-19*01 ORF, IGLV3-2*01 F, IGLV3-21*01 F, IGLV3-23*01 P, IGLV3-23-1*01 P, IGLV3-24*01 F, IGLV3-25*01 ORF, IGLV3-26*01 F, IGLV3-27*01 F, IGLV3-28*01 F, IGLV3-29*01 F, IGLV3-3*01 F, IGLV3-30*01 F, IGLV3-4*01 F, IGLV3-7*01 P, IGLV3-7-1*01 P, IGLV3-8*01 F, IGLV3-9*01 P, IGLV4-10*01 F, IGLV4-12*01 P, IGLV4-16*01 ORF, IGLV4-17*01 P, IGLV4-20*01 ORF, IGLV4-22*01 F, IGLV4-5*01 F, IGLV4-6*01 P, IGLV5-101-1*01 P, IGLV5-103-1*01 P, IGLV5-105*01 P, IGLV5-105-1*01 P, IGLV5-106-1*01 P, IGLV5-109*01 F, IGLV5-110-1*01 P, IGLV5-111-1*01 P, IGLV5-111-2*01 P, IGLV5-113-2*01 P, IGLV5-114-1*01 P, IGLV5-115-1*01 P, IGLV5-118-1*01 P, IGLV5-124-1*01 P, IGLV5-125-1*01 P, IGLV5-126*01 P, IGLV5-128-1*01 P, IGLV5-129-1*01 P, IGLV5-129-2*01 P, IGLV5-131*01 F, IGLV5-132-1*01 P, IGLV5-134*01 P, IGLV5-134-1*01 P, IGLV5-135-1*01 P, IGLV5-137-1*01 P, IGLV5-137-2*01 P, IGLV5-138-1*01 P, IGLV5-139-1*01 P, IGLV5-145*01 P, IGLV5-145-1*01 P, IGLV5-146-1*01 P, IGLV5-148*01 P, IGLV5-148-1*01 P, IGLV5-148-2*01 P, IGLV5-149-1*01 P, IGLV5-150-2*01 P, IGLV5-154-1*01 P, IGLV5-155-1*01 P, IGLV5-157-1*01 P, IGLV5-158-1*01 P, IGLV5-158-2*01 P, IGLV5-158-3*01 P, IGLV5-34*01 P, IGLV5-38*01 P, IGLV5-38-1*01 P, IGLV5-40-1*01 P, IGLV5-42*01 P, IGLV5-47*01 P, IGLV5-47-1*01 P, IGLV5-48-1*01 P, IGLV5-49-1*01 P, IGLV5-51*01 P, IGLV5-53*01 P, IGLV5-53-1*01 P, IGLV5-57-1*01 P, IGLV5-58-1*01 P, IGLV5-59*01 P, IGLV5-62*01 P, IGLV5-64*01 F, IGLV5-67-1*01 P, IGLV5-70-1*01 P, IGLV5-72-1*01 P, IGLV5-76*01 P, IGLV5-77*01 P, IGLV5-77-1*01 P, IGLV5-78-1*01 P, IGLV5-83-1*01 P, IGLV5-85*01 F, IGLV5-86-1*01 P, IGLV5-88-1*01 P, IGLV5-89-1*01 P, IGLV5-92-2*01 P, IGLV5-94-1*01 P, IGLV5-95*01 P, IGLV5-96-1*01 P, IGLV5-97-1*01 P, IGLV5-97-2*01 P, IGLV5-97-3*01 P, IGLV7-120-1*01 P, IGLV7-32-2*01 P, IGLV7-33*01 P, IGLV7-36-1*01 P, IGLV7-38-2*01 P, IGLV7-43-1*01 P, IGLV7-44-1*01 P, IGLV7-84-2*01 P, IGLV7-90-2*01 P, IGLV8-102*01 ORF, IGLV8-108*01 F, IGLV8-113*01 P, IGLV8-113-3*01 P, IGLV8-117*01 P, IGLV8-118-3*01 P, IGLV8-119*01 P, IGLV8-120*01 P, IGLV8-121*01 P, IGLV8-121-1*01 P, IGLV8-124*01 P, IGLV8-128*01 F, IGLV8-137*01 P, IGLV8-142*01 F, IGLV8-150-1*01 ORF, IGLV8-153*01 F, IGLV8-156*01 P, IGLV8-161*01 F, IGLV8-36*01 F, IGLV8-39*01 F, IGLV8-40*01 P, IGLV8-43*01 P, IGLV8-60*01 P, IGLV8-71*01 P, IGLV8-74-1*01 ORF, IGLV8-76-1*01 P, IGLV8-88-4*01 P, IGLV8-89-3*01 P, IGLV8-90*01 P, IGLV8-90-1*01 P, IGLV8-90-3*01 P, IGLV8-90-4*01 P, IGLV8-92-1*01 P, IGLV8-93*01 F, IGLV8-99*01 F.
- Addition of 9 IGLJ genes and 9 alleles (9 F): IGLJ1*01 F, IGLJ2*01 F, IGLJ3*01 F, IGLJ4*01 F, IGLJ5*01 F, IGLJ6*01 F, IGLJ7*01 F, IGLJ8*01 F, IGLJ9*01 F.
- Addition of 9 IGLC genes and 9 IGLC alleles (9 F): IGLC1*01 F, IGLC2*01 F, IGLC3*01 F, IGLC4*01 F, IGLC5*01 F, IGLC6*01 F, IGLC7*01 F, IGLC8*01 F, IGLC9*01 F
26 July 2018 - Update of the Tursiops truncatus (Bottlenose dolphin) TRG reference directory:
- IMGT reference accession number of Tursiops truncatus TRG genes and alleles TRGV1*01, TRGV2*01, TRGJ1*01, TRGJ2*01, TRGJ3*01 and TRGC*01 is JH473572 in IMGT/LIGM-DB.
- Update of the Tursiops truncatus TRG allele nomenclature:
  
  TRG allele old name TRG allele new name
  
  TRGV2*01 TRGV2*02
  
  TRGJ3*01 TRGJ3*02
- Addition of TRGV2*01 F and TRGJ3*01 F.
24 July 2018
- Update of Homo sapiens (human) IGHV reference directory:
  - Addition of 3 IGHV genes and alleles (2 F, 1 ORF): IGHV1-2*06 F, IGHV1-69*17 F, IGHV3-20*03 ORF.
- Creation of the Tursiops truncatus (Bottlenose dolphin) TRG reference directory:
  - Addition of 2 genes and alleles TRGV (2 F): TRGV1*01 F and TRGV2*02 F.
  - Addition of 3 genes and alleles TRGJ (3 F): TRGJ1*01 F, TRGJ2*01 F and TRGJ3*01 F.
  - Addition of TRGC*01 F.
19 July 2018 - Update of the Homo sapiens (human) TRGV reference directory:
- TRGV1*01: removal of the reference sequence X15269 (see IMGT note (1) in Gene table: human (Homo sapiens) TRGV).
- TRGV2*01: removal of the reference sequence X15270 (see IMGT note (13) in Gene table: human (Homo sapiens) TRGV).
- TRGV3*01: removal of the reference sequence X15271 (see IMGT note (15) in Gene table: human (Homo sapiens) TRGV).
- TRGV8*01: removal of the reference sequence X15273 (see IMGT note (16) in Gene table: human (Homo sapiens) TRGV).
13 July 2018 - Update of the Homo sapiens (human) TRBV reference directory:
- Removal of TRBV6-2*02 and TRBV6-2*03 alleles: see IMGT note (40) in Gene table: human (Homo sapiens) TRBV.
12 July 2018 - Update of the Homo sapiens (human) TRBV reference directory:
- TRBV11-3*04 reference sequence is AB305924.
11 July 2018 - Update of the Homo sapiens (human) TRGJ reference directory:
- TRGJ1*02 reference sequence is IMGT000011.
27 June 2018 - Creation of the Gallus gallus (chicken) IGHC reference directory:
- Addition of IGHA*01 (F), IGHM*01 (F) et IGHY*01 (F).

26 June 2018 - Update of the Macaca mulatta (Rhesus monkey) TRAJ nomenclature:

TRAJ gene and allele old name	TRAJ gene and allele new name
TRAJ1	TRAJ61
TRAJ2	TRAJ60
TRAJ3	TRAJ59
TRAJ4	TRAJ58
TRAJ5	TRAJ57
TRAJ6	TRAJ56
TRAJ7	TRAJ55
TRAJ8	TRAJ54
TRAJ9	TRAJ53
TRAJ10	TRAJ52
TRAJ11	TRAJ51
TRAJ12	TRAJ50
TRAJ13	TRAJ49
TRAJ14	TRAJ48
TRAJ15	TRAJ47
TRAJ16	TRAJ46
TRAJ17	TRAJ45
TRAJ18	TRAJ44
TRAJ19	TRAJ43
TRAJ20	TRAJ42
TRAJ21	TRAJ41
TRAJ22	TRAJ40
TRAJ23	TRAJ39
TRAJ24	TRAJ38
TRAJ25	TRAJ37
TRAJ26	TRAJ36
TRAJ27	TRAJ35
TRAJ28	TRAJ34
TRAJ29	TRAJ33
TRAJ30	TRAJ32
TRAJ31	TRAJ31
TRAJ32	TRAJ30
TRAJ33	TRAJ29
TRAJ34	TRAJ28
TRAJ35	TRAJ27
TRAJ36	TRAJ26
TRAJ37	TRAJ25
TRAJ38	TRAJ24
TRAJ39	TRAJ23
TRAJ40	TRAJ22
TRAJ41	TRAJ21
TRAJ42	TRAJ20
TRAJ43	TRAJ19
TRAJ44	TRAJ18
TRAJ45	TRAJ17
TRAJ46	TRAJ16
TRAJ47	TRAJ15
TRAJ48	TRAJ14
TRAJ49	TRAJ13
TRAJ50	TRAJ12
TRAJ51	TRAJ11
TRAJ52	TRAJ10
TRAJ53	TRAJ9
TRAJ54	TRAJ8
TRAJ55	TRAJ7
TRAJ56	TRAJ6
TRAJ57	TRAJ5
TRAJ58	TRAJ4
TRAJ59	TRAJ3
TRAJ60	TRAJ2
TRAJ61	TRAJ1

15 June 2018 - Update of the Gallus gallus (chicken) IGLV reference directory:
- Removal of IGLV1-1*03 gene and allele.
14 June 2018 - Update of the Macaca fascicularis (crab-eating macaque) IGHV reference directory:
- IGHV3S38*01 P: Addition of the gapped sequence according to the IMGT unique numbering.
13 June 2018 - Update of the Macaca mulatta (Rhesus monkey) TRDC reference directory:
- TRDC*01 functionality is ORF (because of noncanonical acceptor splice).

12 June 2018

Update of the Macaca mulatta (Rhesus monkey) TRAV nomenclature

TRAV gene and allele old name	TRAV gene and allele new name
TRAV9-1*01	TRAVA*01
TRAV22-1*01	TRAVB*01
TRAV19-2*01	TRAVC*01
TRAV9-2*01	TRAV9-1*01
TRAV9-3*01	TRAV9-2*01
TRAV22-2*01	TRAV22-1*01
TRAV22-3*01	TRAV22-2*01
TRAV19-1*01	TRAV19*01

Creation of the Gallus gallus (chicken) IGL reference directory:

- Addition of 54 genes and alleles IGLV (4 F, 48 P): IGLV1-1*01 F, IGLV1-1*02 F, IGLV1-1*03 F, IGLV1-2*01 P, IGLV1-2*02 P, IGLV1-2*03 P, IGLV1-3*01 P, IGLV1-3*02 P, IGLV1-3*03 P, IGLV1-4*01 P, IGLV1-4*02 P, IGLV1-5*01 P, IGLV1-5*02 P, IGLV1-6*01 P, IGLV1-6*02 P, IGLV1-7*01 P, IGLV1-8*01 P, IGLV1-8*02 P, IGLV1-9*01 P, IGLV1-9*02 P, IGLV1-10*01 P, IGLV1-11*01 P, IGLV1-11*02 P, IGLV1-12*01 P, IGLV1-13*01 P, IGLV1-14*01 P, IGLV1-14*02 P, IGLV1-15*01 P, IGLV1-15*02 P, IGLV1-16*01 P, IGLV1-16*02 P, IGLV1-17*01 P, IGLV1-18*01 P, IGLV1-19*01 P, IGLV1-19*02 P, IGLV1-20*01 P, IGLV1-20*02 P, IGLV1-21*01 P, IGLV1-22*01 P, IGLV1-22*02 P, IGLV1-23*01 P, IGLV1S1*01 F, IGLV1S2*01 P, IGLV1S3*01 P, IGLV1S4*01 P, IGLV1S5*01 P, IGLV1S6*01 P, IGLV1S7*01 P, IGLV1S8*01 P, IGLV1S9*01 P, IGLV1S10*01 P, IGLV1S11*01 P.
- Addition of IGLC*01 F.
- Addition of IGLJ*01 F.

11 June 2018 - Update of Mus musculus (mouse) TRAJ reference directory :
- TRAJ3*01 functionality is P.
- TRAJ20*01 functionality is P.
- TRAJ46*01 functionality is P.
- TRAJ59*01 functionality is P.
6 June 2018 - Update of Homo sapiens (human) TRAJ reference directory
- TRAJ13*02 reference sequence is AB258131.
4 June 2018
- Creation of Macaca mulatta (Rhesus monkey) TRAC reference directory :
  - Addition of Macaca mulatta (Rhesus monkey) TRAC*01 F gene and allele.
- Creation of Macaca mulatta (Rhesus monkey) TRDC reference directory :
  - Addition of Macaca mulatta (Rhesus monkey) TRDC*01 F gene and allele.
31 May 2018 - Update of Mus musculus (mouse) TRAJ reference directory :
- Addition of TRAJ4*02 F gene and allele.
- TRAJ4*01 functionality is P.
29 May 2018 - Creation of Macaca mulatta (Rhesus monkey) TRAV reference directory :
- Addition of 60 TRAV genes and alleles (41 F, 8 ORF, 11 P): TRAV1-1*01 ORF, TRAV1-2*01 ORF, TRAV10*01 F, TRAV11-1*01 ORF, TRAV11-2*01 P, TRAV11-3*01 P,TRAV12-1*01 F, TRAV12-2*01 F, TRAV12-3*01 F, TRAV13-1*01 F, TRAV13-2*01 F, TRAV14-1*01 P, TRAV15*01 P, TRAV14-2*01 F, TRAV16*01 F, TRAV17*01 F, TRAV18*01 F, TRAV19-1*01 F, TRAV19-2*01 P, TRAV2*01 F, TRAV20*01 F, TRAV21*01 F, TRAV22-1*01 P, TRAV22-2*01 F, TRAV22-3*01 F, TRAV23-1*01 F, TRAV23-2*01 F, TRAV23-3*01 F, TRAV24*01 F, TRAV25*01 ORF, TRAV26-1*01 F, TRAV26-2*01 F, TRAV27*01 F, TRAV29*01 F, TRAV3*01 F, TRAV30*01 ORF, TRAV32*01 P, TRAV33*01 P,TRAV34*01 ORF, TRAV35*01 F, TRAV36*01 F, TRAV37*01 ORF, TRAV38-1*01 F, TRAV38-2*01 F, TRAV39*01 F, TRAV4*01 ORF, TRAV40*01 F, TRAV41*01 F, TRAV5*01 F, TRAV6*01 F, TRAV8-1*01 P, TRAV8-2*01 F, TRAV8-3*01 F, TRAV8-4*01 F, TRAV8-5*01 F, TRAV8-6*01 P,TRAV8-7*01 F, TRAV9-1*01 P, TRAV9-2*01 F, TRAV9-3*01 F.
28 May 2018
- Creation of Macaca mulatta (Rhesus monkey) TRAJ reference directory :
  - Addition of 61 TRAJ genes and alleles TRAJ (49 F, 7 ORF, 5P): TRAJ1*01 ORF, TRAJ10*01 F, TRAJ11*01 P, TRAJ12*01 F, TRAJ13*01 F, TRAJ14*01 F, TRAJ15*01 F, TRAJ16*01 F, TRAJ17*01 F, TRAJ18*01 F, TRAJ19*01 F, TRAJ2*01 ORF, TRAJ20*01 F, TRAJ21*01 F, TRAJ22*01 F, TRAJ23*01 F, TRAJ24*01 F, TRAJ25*01 F, TRAJ26*01 F, TRAJ27*01 F, TRAJ28*01 F, TRAJ29*01 F, TRAJ3*01 P, TRAJ30*01 F, TRAJ31*01 F, TRAJ32*01 F, TRAJ33*01 F, TRAJ34*01 F, TRAJ35*01 F, TRAJ36*01 F, TRAJ37*01 F, TRAJ38*01 F, TRAJ39*01 F, TRAJ4*01 P, TRAJ40*01 F, TRAJ41*01 F, TRAJ42*01 ORF, TRAJ43*01 ORF, TRAJ44*01 F, TRAJ45*01 F, TRAJ46*01 F, TRAJ47*01 ORF, TRAJ48*01 ORF, TRAJ49*01 F, TRAJ5*01 F, TRAJ50*01 F, TRAJ51*01 F, TRAJ52*01 F, TRAJ53*01 F, TRAJ54*01 F, TRAJ55*01 F, TRAJ56*01 F, TRAJ57*01 F, TRAJ58*01 F, TRAJ59*01 F, TRAJ6*01 F, TRAJ60*01 ORF, TRAJ61*01 P, TRAJ7*01 P, TRAJ8*01 F, TRAJ9*01 F.
  - Addition of 51 TRAV genes and alleles (41 F, 8 ORF, 2P): TRAV1-1*01 ORF, TRAV1-2*01 ORF, TRAV10*01 F, TRAV11-1*01 ORF, TRAV11-2*01 P, TRAV12-1*01 F, TRAV12-2*01 F, TRAV12-3*01 F, TRAV13-1*01 F, TRAV13-2*01 F, TRAV14-2*01 F, TRAV16*01 F, TRAV17*01 F, TRAV18*01 F, TRAV19-1*01 F, TRAV2*01 F, TRAV20*01 F, TRAV21*01 F, TRAV22-2*01 F, TRAV22-3*01 F, TRAV23-1*01 F, TRAV23-2*01 F, TRAV23-3*01 F, TRAV24*01 F, TRAV25*01 ORF, TRAV26-1*01 F, TRAV26-2*01 F, TRAV27*01 F, TRAV29*01 F, TRAV3*01 F, TRAV30*01 ORF, TRAV34*01 ORF, TRAV35*01 F, TRAV36*01 F, TRAV37*01 ORF, TRAV38-1*01 F, TRAV38-2*01 F, TRAV39*01 F, TRAV4*01 ORF, TRAV40*01 F, TRAV41*01 F, TRAV5*01 F, TRAV6*01 F, TRAV8-1*01 P, TRAV8-2*01 F, TRAV8-3*01 F, TRAV8-4*01 F, TRAV8-5*01 F, TRAV8-7*01 F, TRAV9-2*01 F, TRAV9-3*01 F.
- Creation of Macaca mulatta (Rhesus monkey) TRDV reference directory :
  - Addition of 3 TRDV genes and alleles (2 F, 1 ORF): TRDV1*01 F, TRDV2*01 F, TRDV3*01 ORF.
- Creation of Macaca mulatta (Rhesus monkey) TRDD reference directory :
  - Addition of 4 TRDD genes and alleles (2 F, 2 ORF): TRDD1*01 ORF, TRDD2*01 F, TRDD3*01 ORF, TRDD4*01 F.
- Creation of Macaca mulatta (Rhesus monkey) TRDJ reference directory :
  - Addition of 4 TRDJ genes and alleles (4 F): TRDJ1*01 F, TRDJ2*01 F, TRDJ3*01 F, TRDJ4*01 F.
16 May 2018 - Creation of Gallus gallus (chicken) IGHD reference directory:
- Addition of 4 Gallus gallus (chicken) IGHD genes and alleles (3 F and 1 ORF) : IGHD1*01 F, IGHD2*01 F, IGHD3*01 ORF, IGHD4*01 F.
14 May 2018 - Update of Mus musculus (mouse) IGHV reference directory:
- IGHV1-17-1*01 reference sequence is AC090843.
- IGHV1-17-1*01 functionality is P.
- IGHV6-4*02 functionality is ORF.
- IGHV6-5*02 functionality is ORF.
27 April 2018 - Update of Gallus gallus (chicken) IGHV IMGT gene names :
- IGHV1-31*02 -> IGHV1S9*01.
- IGHV1-53*02 -> IGHV1S10*01.
20 April 2018 - Update of Gallus gallus (chicken) IGHV reference directory:
- Addition of 15 IGHV genes and alleles (15 P):IGHV1-28D*02, IGHV1-28N*01, IGHV1-29D*01, IGHV1-29N*01, IGHV1-30D*01, IGHV1-30N*01, IGHV1-53-1*01, IGHV1-59-1*01, IGHV1-61-1*01, IGHV1-61-2*01, IGHV1-62D*01, IGHV1-62D-1*01, IGHV1-62D-2*01, IGHV1-62D-3*01 and IGHV1-62D-4*01.
- Update of Gallus gallus (chicken) IMGT gene names:
  - IGHV1S6*01 -> IGHV1-62D-1*02.
  - IGHV1S7*01 -> IGHV1S6*01.
  - IGHV1S8*01 -> IGHV1-61*03.
  - IGHV1S9*01 -> IGHV1S7*01.
  - IGHV1S10*01 -> IGHV1S8*01.
4 April 2018 - Update of Canis lupus familiaris (dog) TRGV reference directory:
- Functionality of Canis lupus familiaris (dog) TRGV4*01 is ORF.
- Functionality of Canis lupus familiaris (dog) TRGJ1-2*01 is ORF.
28 March 2018
- Update of Homo sapiens (human) IGHV reference directory:
  - Addition of 8 IGHV genes and alleles (8 F):IGHV1-8*03, IGHV1-69*15, IGHV1-69*16, IGHV2-26*02, IGHV2-26*03, IGHV2-70*15, IGHV2-70*16, IGHV2-70*17.
  - Update of reference sequences of IGHV1-45*03 and IGHV2-70*04 (partial sequences were replaced with complete V-REGION).
- Update of Gallus gallus (chicken) IGH reference directory:
  - Addition of 1 IGHJ gene and allele (1 F): IGHJ1*01.
  - Addition of 17 IGHV genes and alleles (1 F and 16 P): IGHV1-21*02 P, IGHV1-31*02 P, IGHV1-35*02 P, IGHV1-36*02 P, IGHV1-51*02 P, IGHV1-53*02 P, IGHV1-60*02 P, IGHV1S1*01 F, IGHV1S10*01 P, IGHV1S2*01 P, IGHV1S3*01 P, IGHV1S4*01 P, IGHV1S5*01 P, IGHV1S6*01 P, IGHV1S7*01 P, IGHV1S8*01 P, IGHV1S9*01 P.
21 March 2018 - Update of Capra hircus (goat) IGK reference directory:
- Functionality of Capra hircus (goat) IGKJ1*01, IGKJ2*01 and IGKJ4*01 is ORF.
- Functionality of Capra hircus (goat) IGKV8-3 is ORF.
20 March 2018 - Update of Ovis aries (sheep) IGKJ reference direcrory:
- Functionality of Ovis aries (sheep) IGKJ1*01 is ORF.
15 March 2018 - Creation of Gallus gallus (chicken) IGHV reference directory:
- Addition of 79 Gallus gallus (chicken) IGHV genes and alleles (1 F and 78 P) : IGHV1-1*01 F, IGHV1-10*01 P, IGHV1-11*01 P, IGHV1-12*01 P, IGHV1-13*01 P, IGHV1-14*01 P, IGHV1-15*01 P, IGHV1-16*01 P, IGHV1-17*01 P, IGHV1-18*01 P, IGHV1-19*01 P, IGHV1-2*01 P, IGHV1-20*01 P, IGHV1-21*01 P, IGHV1-22*01 P, IGHV1-23*01 P, IGHV1-24*01 P, IGHV1-25*01 P, IGHV1-26*01 P, IGHV1-28*01 P, IGHV1-29*01 P, IGHV1-3*01 P, IGHV1-30*01 P, IGHV1-31*01 P, IGHV1-32*01 P, IGHV1-34*01 P, IGHV1-35*01 P, IGHV1-36*01 P, IGHV1-37*01 P, IGHV1-38*01 P, IGHV1-39*01 P, IGHV1-4*01 P, IGHV1-40*01 P, IGHV1-41*01 P, IGHV1-42*01 P, IGHV1-43*01 P, IGHV1-44*01 P, IGHV1-45*01 P, IGHV1-46*01 P, IGHV1-47*01 P, IGHV1-48*01 P, IGHV1-49*01 P, IGHV1-5*01 P, IGHV1-50*01 P, IGHV1-51*01 P, IGHV1-53*01 P, IGHV1-54*01 P, IGHV1-55*01 P, IGHV1-56*01 P, IGHV1-57*01 P, IGHV1-58*01 P, IGHV1-59*01 P, IGHV1-6*01 P, IGHV1-60*01 P, IGHV1-61*01 P, IGHV1-62*01 P, IGHV1-63*01 P, IGHV1-65*01 P, IGHV1-66*01 P, IGHV1-67*01 P, IGHV1-68*01 P, IGHV1-69*01 P, IGHV1-7*01 P, IGHV1-70*01 P, IGHV1-71*01 P, IGHV1-72*01 P, IGHV1-73*01 P, IGHV1-74*01 P, IGHV1-75*01 P, IGHV1-76*01 P, IGHV1-77*01 P, IGHV1-78*01 P, IGHV1-79*01 P, IGHV1-8*01 P, IGHV1-80*01 P, IGHV1-81*01 P, IGHV1-82*01 P, IGHV1-83*01 P, IGHV1-9*01 P.
13 March 2018 - Update of Bos taurus (bovine) IGH reference directory:
- Addition of Bos taurus (bovine) IGHV1S1*01 gene and allele.
- Removal of the Bos taurus (bovine) IGHV alleles IGHV1-25*02, IGHV1-33*02, IGHV1-33*03 and IGHV1-37*03.
- Removal of Bos taurus (bovine) IGHD9-1*02.
15 February 2018 - Update of Ovis aries (sheep) IGKV reference directory:
- Addition of 6 Ovis aries (sheep) IGKV genes and alleles (6 P): IGKV(II)-13, IGKV(II)-16, IGKV(II)-19, IGKV(II)-2, IGKV2-18, IGKV3-20.
7 February 2018 - Update of Homo sapiens (human) TRGV reference directory:
- Addition of TRGV2*03 F and TRGVB*02 P alleles.
6 February 2018 - Update of Capra hircus (goat) IGKC reference directory:
- The reference sequence of Capra hircus (goat) IGKC*01 is JO556991, functionality of Capra hircus (goat) IGKC*01 is F.
5 February 2018 - Creation of Ovis aries (sheep) IGK reference directory:
- Addition of Ovis aries (sheep) IGK genes and alleles:
  - 12 IGKV (5 F, 1 ORF, 6 P): IGKV1-1*01 P, IGKV1-17*01 P, IGKV1-21*01 ORF, IGKV1-4*01 F, IGKV1-6*01 P, IGKV1-7*01 P, IGKV2-14*01 F, IGKV2-15*01 P, IGKV2-8*01 F, IGKV2-9*01 P, IGKV6-5*01 F, IGKV8-3*01 F.
  - 4 IGKJ (2 F, 2 ORF): IGKJ1*01 F, IGKJ2*01 ORF, IGKJ3*01 F, IGKJ4*01 ORF.
  - IGKC*01 F.

31 January 2018 - Update of the Capra hircus (goat) IGKV nomenclature:

IGKV gene and allele old name	IGKV gene and allele new name
IGKV1-1*01	IGKV1-1*01
IGKV(II)-1-1*01	IGKV(II)-2*01
IGKV1-2*01	IGKV8-3*01
IGKV1-3*01	IGKV1-4*01
IGKV(II)-4*01	IGKV6-5*01
IGKV1-5*01	IGKV1-6*01
IGKV1-6*01	IGKV1-7*01
IGKV2-7*01	IGKV2-8*01
IGKV2-8*01	IGKV2-9*01
IGKV(II)-8-1*01	IGKV(II)-10*01
IGKV2-9*01	IGKV2-11*01
IGKV(II)-9-1*01	IGKV(II)-12*01
IGKV(II)-9-2*01	IGKV(II)-13*01
IGKV2-10*01	IGKV2-14*01
IGKV2-11*01	IGKV2-15*01
IGKV(I)-11-1*01	IGKV(II)-16*01
IGKV1-12*01	IGKV1-17*01
IGKV2-13*01	IGKV2-18*01
-	IGKV(II)-19*01
IGKV3-14*01	IGKV3-20*01
IGKV1-15*01	IGKV1-21*01

12 January 2018 - Update of Canis lupus familiaris (dog) TRGC reference directory:
- IMGT locus reference sequence is IMGT000006 in IMGT/LIGM-DB for TRGC5*01 F
11 January 2018 - Update of Canis lupus familiaris (dog) TRGC reference directory:
- IMGT locus reference sequence is IMGT000006 in IMGT/LIGM-DB for 7 TRGC genes and alleles (5 F, 1 ORF, 1P) : TRGC1*01 ORF, TRGC2*01 F, TRGC3*01 F, TRGC4*01 F, TRGC6*01 P, TRGC7*01 F, TRGC8*01 F.
10 January 2018 - Update of Canis lupus familiaris (dog) TRGJ reference directory:
- IMGT locus reference sequence is IMGT000006 in IMGT/LIGM-DB for 10 TRGJ genes and alleles (5 F, 2 ORF, 3 P) TRGJ4-1*01 P, TRGJ4-2*01 F, TRGJ5-1*01 ORF, TRGJ5-2*01 F, TRGJ6-1*01 F, TRGJ6-2*01 ORF, TRGJ7-1*01 P, TRGJ7-2*01 F, TRGJ8-1*01 F, TRGJ8-2*01 P.
9 January 2018
- Update of Canis lupus familiaris (dog) TRGJ reference directory:
  - IMGT locus reference sequence is IMGT000006 in IMGT/LIGM-DB for 6 TRGJ genes and alleles (2 F, 1 ORF, 3 P): TRGJ1-1*01 P, TRGJ1-2*01 F, TRGJ2-1*01 P, TRGJ2-2*01 F, TRGJ3-1*01 P, TRGJ3-2*01 ORF.
- Update of Canis lupus familiaris (dog) TRGV reference directory
  - IMGT locus reference sequence is IMGT000006 in IMGT/LIGM-DB for 16 TRGV genes and alleles (8 F, 8 P): TRGV1-1*01 P, TRGV2-1*01 F, TRGV2-2*01 F, TRGV2-3*01 F, TRGV2-4*01 F, TRGV3-1*01 P, TRGV3-2*01 P, TRGV3-3*01 P, TRGV4-1*01 F, TRGV5-1*01 P, TRGV5-2*01 F, TRGV5-3*01 P, TRGV6-1*01 P, TRGV7-1*01 P, TRGV7-2*01 F, TRGV7-3*01 F.
  - Addition of Canis lupus familiaris (dog) TRGV5-3*01 gene and allele.
15 December 2017
- Addition of Capra hircus (goat) IGK genes and alleles:
  - 20 IGKV (5 F, 2 ORF, 13 P): IGKV(I)-11-1*01 P, IGKV(II)-1-1*01 P, IGKV(II)-4*01 P, IGKV(II)-8-1*01 P,IGKV(II)-9-1*01 P, IGKV(II)-9-2*01 P, IGKV1-1*01 ORF, IGKV1-12*01 P, IGKV1-15*01 P, IGKV1-2*01 P, IGKV1-3*01 F, IGKV1-5*01 P, IGKV1-6*01 P, IGKV2-10*01 F, IGKV2-11*01 F, IGKV2-13*01 P, IGKV2-7*01 F, IGKV2-8*01 F, IGKV2-9*01 ORF, and IGKV3-14*01 P.
  - 4 IGKJ (4 F): IGKJ1*01 F, IGKJ2*01 F, IGKJ3*01 F, and IGKJ4*01 F.
  - IGKC*01 P.
12 December 2017
- Updates (functionality change): Canis lupus familiaris (dog) IGKJ5*01 is F.
- Addition of Canis lupus familiaris (dog) gene and allele IGKV2S15*01 P.
08 December 2017
- Functionality: Canis lupus familiaris (dog) TRBJ2-1 is F (see related note in Dog TRBJ gene table).
30 November 2017
- Functionality: Canis lupus familiaris (dog) TRBV26*01 is F, Canis lupus familiaris (dog) TRBV28*01 is F (see related note in Dog TRBV gene table).
27 November 2017
- Update of Danio rerio (zebrafish) TRAV reference directory:
  - TRAV22-3*02 is TRAV22-3/DV2-1*02.
  - TRAV22-4*02 is TRAV22-4/DV2-2*02.
  - TRAV22-4*03 is TRAV22-4/DV2-2*03.
24 October 2017
- Addition of 89 Canis lupus familiaris IGHV genes and alleles: IGHV3-83*01 P, IGHV3-82*01 F, IGHV3-81*01 F, IGHV3-80*01 F, IGHV3-79*01 P, IGHV3-78*01 P, IGHV3-77*01 P, IGHV3-76*01 F, IGHV3-75*01 F, IGHV3-74*01 P, IGHV3-73*01 P, IGHV3-72*01 P, IGHV3-71*01 P, IGHV3-70*01 F, IGHV3-69*01 F, IGHV3-68*01 P, IGHV3-67*01 F, IGHV3-66*01 P, IGHV3-65*01 P, IGHV3-64*01 P, IGHV3-63*01 P, IGHV3-62*01 P, IGHV3-61*01 F, IGHV3-60*01 P, IGHV3-59*01 P, IGHV3-58*01 F, IGHV3-57*01 P, IGHV3-56*01 P, IGHV3-55*01 P, IGHV3-54*01 F, IGHV3-53*01 P, IGHV3-52*01 P, IGHV3-51*01 P, IGHV3-50*01 F, IGHV3-49*01 P, IGHV3-48*01 P, IGHV3-47-1*01 P, IGHV3-47*01 F, IGHV3-46*01 F, IGHV3-45*01 P, IGHV3-44*01 ORF, IGHV3-43*01 P, IGHV3-42*01 P, IGHV3-41*01 F, IGHV3-40*01 P, IGHV3-39*01 F, IGHV3-38*01 F, IGHV3-37*01 F, IGHV3-36*01 P, IGHV3-35*01 F, IGHV3-34*01 F, IGHV3-33*01 P, IGHV3-32*01 ORF, IGHV3-31*01 P, IGHV1-30*01 F, IGHV3-29*01 P, IGHV3-28*01 P, IGHV3-27*01 P, IGHV3-26*01 P, IGHV3-25*01 P, IGHV3-24*01 F, IGHV3-23*01 F, IGHV3-22*01 P, IGHV3-21-1*01 P, IGHV3-21*01 P, IGHV3-20*01 P, IGHV3-19*01 F, IGHV3-18*01 F, IGHV1-17*01 P, IGHV3-16*01 F, IGHV1-15*01 P, IGHV3-14*01 P, IGHV3-13*01 F, IGHV(II)-1*01 P, IGHV3-12*01 P, IGHV3-11*01 P, IGHV3-10*01 F, IGHV3-9*01 F, IGHV3-8*01 F, IGHV3-7*01 F, IGHV3-6*01 F, IGHV(II)-2*01 P, IGHV3-5-1*01 P, IGHV3-5*01 F, IGHV1-4-1*01 P, IGHV3-4*01 P, IGHV3-3*01 F, IGHV3-2*01 F, IGHV4-1*01 F.
- Addition of 6 Canis lupus familiaris IGHD genes: IGHD1*01*01 F, IGHD2*01*01 F, IGHD3*01*01 F, IGHD4*01*01 F, IGHD5*01*01 ORF, IGHD6*01*01 F.
- Addition of 6 Canis lupus familiaris IGHJ genes and alleles: IGHJ1*01*01 ORF, IGHJ2*01*01 F, IGHJ3*01*01 F, IGHJ4*01*01 F, IGHJ5*01*01 F, IGHJ6*01*01 F.
18 October 2017 - Update of Bos taurus (bovine) IGH reference directory:
- Addition of 8 IGHV alleles: IGHV1-21*02 F, IGHV1-21*03 F, IGHV1-25*02 F, IGHV1-33*02 F, IGHV1-33*03 F, IGHV1-37*03 F, IGHV2-23*02 P, IGHV2-35*02 P.
- Addition of 1 IGHD allele: IGHD9-1*02 ORF.
17 October 2017
- Updates (functionality change) : Canis lupus familiaris (dog) IGKV4-1 is ORF.
16 October 2017 - Update of Bos taurus (bovine) IGH reference directory:
- Addition of 2 genes and 19 IGHV alleles: IGHV1-10*02 F, IGHV1-14*02 F, IGHV1-14*03 F, IGHV1-20*02 F, IGHV1-30*02 F, IGHV1-30*03 F, IGHV1-32*02 P, IGHV1-37*02 F, IGHV1-39*02 F, IGHV1-39*03 F, IGHV1-46*02 P, IGHV1-7*02 F, IGHV1S2*01 P, IGHV2-12*02 P, IGHV2-31*02 P, IGHV2-5*02 P, IGHV2-6*02 P, IGHV2S1*01 P, IGHV3-44*02 P.
- Addition of 6 IGHJ alleles: IGHJ1-1*02 ORF, IGHJ1-1*03 ORF, IGHJ1-2*02 ORF, IGHJ1-2*03 ORF, IGHJ1-3*02 ORF, IGHJ1-4*02 F.
- Addition of 3 IGHC allele: IGHDD1P*02 P, IGM1*03 F, IGH1*04 F.
13 October 2017
- Updates (functionality change) : Canis lupus familiaris (dog) IGKV2S16 is F.
12 October 2017
- Addition of Canis lupus familiaris (dog) IGKV4-1*01 F.
11 October 2017 - Addition of Canis lupus familiaris (dog) IGK genes and alleles:
- Addition of 5 Canis lupus familiaris IGKJ genes and alleles: IGKJ1*01 F, IGKJ2 ORF, IGKJ3 F, IGKJ4 F, IGKJ5 ORF.
- Addition of 1 Canis lupus familiaris IGKC genes and alleles: IGKC*01 F.
- Addition of 12 Canis lupus familiaris IGKV genes and alleles: IGKV2S12*01 P, IGKV2S13*01 F, IGKV2S14*01 P, IGKV2S16*01 P, IGKV2S18*01 P, IGKV2S19*01 F, IGKV3S1*01 F, IGKV3S2*01 P , IGKV3-3*01 P, IGKV4S1*01 F, IGKV7-2*01 P, IGKV(II)-1*01 P.
4 October 2017
- Addition of 47 Bos taurus IGHV genes and 47 alleles: IGHV1-10*01 F, IGHV1-14*01 F, IGHV1-17*01 F, IGHV1-20*01 F, IGHV1-21*01 F, IGHV1-25*01, F, IGHV1-27*01 Bos taurus F, IGHV1-30*01 F, IGHV1-32*01 P, IGHV1-33*01 F, IGHV1-37*01 F, IGHV1-39*01 F, IGHV1-43*01 P, IGHV1-46*01 P, IGHV1-7*01 F, IGHV2-12*01 P, IGHV2-13*01 P, IGHV2-16*01 P, IGHV2-19*01 P, IGHV2-23*01 P, IGHV2-24*01 P, IGHV2-26*01 P, IGHV2-29*01 P, IGHV2-31*01 P, IGHV2-35*01 P, IGHV2-36*01 P, IGHV2-38*01 P, IGHV2-42*01 P, IGHV2-45*01 P, IGHV2-5*01 P, IGHV2-6*01 P, IGHV2-9*01 P, IGHV3-1*01 P, IGHV3-11*01 P, IGHV3-15*01 P, IGHV3-18*01 P, IGHV3-2*01 P, IGHV3-22*01 P, IGHV3-28*01 P, IGHV3-3*01 P, IGHV3-34*01 P, IGHV3-4*01 P, IGHV3-40*01 P, IGHV3-41*01 P, IGHV3-44*01 P, IGHV3-47*01 P, IGHV3-8*01 P.
- Addition of 23 Bos taurus IGHD genes and 23 alleles: IGHD1-1*01 F, IGHD1-2*01 ORF, IGHD1-3*01 ORF, IGHD1-4*01 F, IGHD2-1*01 F, IGHD2-2*01 F, IGHD2-3*01 F, IGHD2-4*01 F, IGHD3-1*01 F, IGHD3-3*01 F, IGHD3-4*01 F, IGHD4-1*01 F, IGHD5-2*01 F, IGHD5-3*0 F, IGHD5-4*01 F, IGHD6-2*01 F, IGHD6-3*01 F, IGHD6-4*01 F, IGHD7-3*01 F, IGHD7-4*01 F, IGHD8-2*01 F, IGHD9-1*01 F, IGHD9-4*01 F.
- Addition of 12 Bos taurus IGHJ genes and 12 alleles: IGHJ1-1*01 ORF, IGHJ1-2*01 ORF, IGHJ1-3*01 ORF, IGHJ1-4*01 F, IGHJ1-5*01 P, IGHJ1-6*01 F, IGHJ2-1*01 ORF, IGHJ2-2*01 ORF, IGHJ2-3*01 ORF, IGHJ2-4*01 F, IGHJ2-5*01 P, IGHJ2-6*01 ORF
- Addition of 12 Bos taurus IGH constant genes and 24 alleles: IGHA*01 F, IGHD*01 P, IGHD*02 ORF, IGHDD1P*01 P, IGHDD2P*01 P, IGHDD3P*01 P, IGHE*01 F, IGHE*02 F, IGHG1*01 F, IGHG1*02 (F), IGHG1*03 (F), IGHG1*04 F, IGHG2*01 F, IGHG2*02 F, IGHG2*03 (F), IGHG2*04 F, IGHG3*01 F, IGHG3*02 F, IGHG3*03 F,IGHGP*01 P, IGHM1*01 F, IGHM1*02 F, IGHM2*01 F, IGHM2*02 F.
- Update of accession numbers of Canis lupus familiaris TRB genes and alleles reference sequences.
3 October 2017
- Addition of Canis lupus familiaris TRBC1*02 allele.
22 September 2017
- Addition of 152 Danio rerio TRAV genes and 284 alleles: TRAV1-1*01 F, TRAV1-1*02 F, TRAV10-1*01 F, TRAV10-1*02 F, TRAV10-2*01 F, TRAV10-2*02 F, TRAV10-3*01 F, TRAV10-4*01 F, TRAV11-1*01 F, TRAV11-1*02 F, TRAV11-2*01 P, TRAV11-3*01 F, TRAV11-3*02 F, TRAV11-4*01 F, TRAV11-4*02 F, TRAV11-4*03 F, TRAV11-5*01 F, TRAV11-5*02 F, TRAV11-5*03 F, TRAV11-6*02 F, TRAV11-6*03 F, TRAV12-1*01 F, TRAV13-1*01 F, TRAV13-2*01 F, TRAV13-2*02 F, TRAV13-2*03 F, TRAV13-3*01 F, TRAV13-3*02 F, TRAV14-1*01 F, TRAV15-1*01 F, TRAV16-1/DV1-1*01 F, TRAV17-1*01 F, TRAV17-1*02 P, TRAV18-1*01 P, TRAV18-1*02 F, TRAV18-10*01 F, TRAV18-10*02 F, TRAV18-10*03 F, TRAV18-11*01 F, TRAV18-11*02 F, TRAV18-11*03 F, TRAV18-11*04 F, TRAV18-12*01 F, TRAV18-12*02 F, TRAV18-12*03 F, TRAV18-2*01 F, TRAV18-2*02 F, TRAV18-3*01 F, TRAV18-4*01 F, TRAV18-5*01 F, TRAV18-6*01 F, TRAV18-7*01 F, TRAV18-7*02 F, TRAV18-8*01 F, TRAV18-8*02 F, TRAV18-9*01 F, TRAV18-9*02 F, TRAV18-9*03 F, TRAV19-1*01 F, TRAV19-1*02 F, TRAV2-1*01 F, TRAV2-1*02 F, TRAV20-1*01 F, TRAV20-1*02 F, TRAV20-2*01 F, TRAV20-3*01 F, TRAV20-3*02 F, TRAV20-3*03 F, TRAV21-1*01 ORF, TRAV21-2*01 F, TRAV21-4*01 F, TRAV21-5*01 F, TRAV22-1*01 P, TRAV22-2*01 P, TRAV22-2*02 P, TRAV22-3*02 F, TRAV22-3/DV2-1*01 F, TRAV22-4*02 F, TRAV22-4*03 F, TRAV22-4/DV2-2*01 F, TRAV23-1*02 F, TRAV24-1*01 F, TRAV24-1*02 F, TRAV24-2*01 F, TRAV24-2*02 F, TRAV24-2*03 F, TRAV25-1*01 ORF, TRAV25-1*02 F, TRAV25-1*03 F, TRAV25-2*01 F, TRAV25-2*02 F, TRAV25-3*01 F, TRAV25-3*02 F, TRAV25-3*03 F, TRAV26-1*01 P, TRAV26-1*02 F, TRAV26-1*03 F, TRAV26-2*01 F, TRAV26-2*02 P, TRAV26-2*03 F, TRAV27-1*01 F, TRAV27-1*02 F, TRAV27-1*03 F, TRAV28-1*01 F, TRAV28-1*03 F, TRAV29-1*01 F, TRAV29-1*02 F, TRAV29-1*03 F, TRAV29-2*01 F, TRAV29-2*02 F, TRAV29-2*03 F, TRAV29-3*01 F, TRAV29-3*02 F, TRAV29-3*03 F, TRAV3-1*01 F, TRAV3-1*02 F, TRAV30-1*01 F, TRAV30-1*02 F, TRAV30-1*03 F, TRAV31-1*01 F, TRAV31-1*02 F, TRAV31-1*03 F, TRAV32-1*01 F, TRAV32-1*02 F, TRAV33-1*01 F, TRAV33-1*02 F, TRAV33-1*03 F, TRAV34-1*01 F, TRAV34-1*02 F, TRAV34-1*03 F, TRAV35-1*01 F, TRAV35-1*02 F, TRAV35-1*03 F, TRAV36-1*01 F, TRAV36-1*02 ORF, TRAV36-1*03 F, TRAV37-1*01 F, TRAV37-1*02 F, TRAV38-1*01 F, TRAV38-1*02 F, TRAV39-1*01 F, TRAV39-1*02 F, TRAV4-1*01 F, TRAV4-1*02 F, TRAV4-2*01 F, TRAV4-2*02 F, TRAV4-3*01 F, TRAV4-3*02 F, TRAV4-4*01 F, TRAV4-5*01 F, TRAV4-6*01 F, TRAV4-6*02 F, TRAV4-6*03 F, TRAV4-7*01 F, TRAV4-7*02 F, TRAV4-7*03 F, TRAV40-1*01 F, TRAV40-1*02 F, TRAV41-1*01 F, TRAV41-1*02 F, TRAV42-1*01 F, TRAV42-1*02 F, TRAV42-2*01 F, TRAV42-2*02 F, TRAV43-1*01 F, TRAV43-1*02 F, TRAV43-2*01 F, TRAV43-2*02 P, TRAV44-1*01 F, TRAV44-1*02 F, TRAV44-2*01 F, TRAV44-2*02 F, TRAV44-3*01 F, TRAV44-3*02 F, TRAV45-1*01 F, TRAV45-1*02 F, TRAV46-1*01 F, TRAV46-1*02 F, TRAV47-1*01 F, TRAV47-1*02 P, TRAV48-1*01 F, TRAV48-1*02 F, TRAV49-1*01 F, TRAV5-1*01 F, TRAV5-1*02 F, TRAV50-1*01 F, TRAV51-1*01 F, TRAV52-1*01 F, TRAV53-1*01 F, TRAV54-1*01 F, TRAV55-1*01 F, TRAV56-1*01 F, TRAV57-1*01 F, TRAV58-1*01 F, TRAV59-1*01 F, TRAV6-1*02 P, TRAV6-2*01 F, TRAV6-2*02 F, TRAV6-3*01 ORF, TRAV6-3*02 F, TRAV6-4*01 ORF, TRAV6-4*02 F, TRAV6-5*01 F, TRAV6-5*02 F, TRAV6-5*03 F, TRAV60-1*01 F, TRAV61-1*01 F, TRAV62-1*01 F, TRAV62-2*01 F, TRAV62-3*01 F, TRAV62-3*02 F, TRAV63-1*01 F, TRAV63-2*01 F, TRAV63-3*01 F, TRAV63-4*01 F, TRAV63-4*02 F, TRAV64-1*01 P, TRAV64-2*02 F, TRAV65-1*01 F, TRAV65-1*02 F, TRAV65-2*01 F, TRAV65-2*02 F, TRAV66-1*01 F, TRAV66-1*02 F, TRAV67-1*01 F, TRAV67-1*02 F, TRAV67-2*01 F, TRAV67-2*02 F, TRAV68-1*01 F, TRAV69-1*01 F, TRAV69-1*02 F, TRAV69-2*01 F, TRAV69-2*02 F, TRAV69-3*01 F, TRAV69-3*02 F, TRAV69-4*01 F, TRAV69-4*02 F, TRAV7-1*01 F, TRAV7-2*01 F, TRAV7-2*02 F, TRAV7-3*01 F, TRAV7-3*02 F, TRAV7-4*01 F, TRAV7-4*02 F, TRAV7-5*01 F, TRAV7-5*02 F, TRAV7-5*03 F, TRAV70-1*01 F, TRAV70-1*02 F, TRAV71-1*01 F, TRAV71-1*02 F, TRAV71-2*01 F, TRAV71-2*02 F, TRAV72-1*01 F, TRAV72-1*02 F, TRAV72-2*01 F, TRAV72-2*02 F, TRAV72-3*01 F, TRAV72-3*02 P, TRAV72-4*01 F, TRAV72-4*02 F, TRAV73-1*01 ORF, TRAV73-2*01 P, TRAV73-2*02 F, TRAV73-3*01 F, TRAV73-3*02 F, TRAV74-1*01 F, TRAV74-1*02 P, TRAV75-1*01 F, TRAV75-1*02 F, TRAV9-1*01 ORF, TRAV9-1*02 F, TRAV9-2*01 F, TRAV9-2*02 F, TRAV9-3*01 F, TRAV9-3*02 F, TRAV9-4*01 F, TRAV9-4*02 F, TRAV9-5*01 F, TRAV9-5*02 F, TRAV9-5-1*01 F, TRAV9-6*01 F, TRAV9-6*02 F, TRAV9-6*03 F.
- Addition of 123 Danio rerio TRAJ genes and 136 alleles: TRAJ1*01 ORF, TRAJ10*01 F, TRAJ100*01 ORF, TRAJ100*02 ORF, TRAJ101*01 F, TRAJ102*01 ORF, TRAJ103*01 F, TRAJ103*02 F, TRAJ104*01 ORF, TRAJ104*02 ORF, TRAJ105*01 F, TRAJ106*01 ORF, TRAJ106*02 ORF, TRAJ107*01 F, TRAJ107*02 F, TRAJ108*01 F, TRAJ108*02 F, TRAJ109*01 ORF, TRAJ109*02 ORF, TRAJ11*01 F, TRAJ110*01 F, TRAJ111*01 F, TRAJ112*01 F, TRAJ113*01 F, TRAJ114*01 ORF, TRAJ115*01 ORF, TRAJ116*01 F, TRAJ117*01 ORF, TRAJ118*01 ORF, TRAJ119*01 P, TRAJ12*01 F, TRAJ120*01 F, TRAJ121*01 F, TRAJ122*01 ORF, TRAJ123*01 F, TRAJ13*01 F, TRAJ14*01 F, TRAJ15*01 F, TRAJ16*01 F, TRAJ17*01 F, TRAJ18*01 F, TRAJ19*01 F, TRAJ2*01 F, TRAJ20*01 F, TRAJ21*01 F, TRAJ22*01 F, TRAJ23*01 F, TRAJ24*01 F, TRAJ25*01 F, TRAJ26*01 F, TRAJ27*01 F, TRAJ28*01 F, TRAJ29*01 F, TRAJ3*01 F, TRAJ30*01 F, TRAJ31*01 F, TRAJ32*01 F, TRAJ33*01 F, TRAJ34*01 F, TRAJ35*01 F, TRAJ36*01 F, TRAJ37*01 F, TRAJ38*01 F, TRAJ39*01 F, TRAJ4*01 F, TRAJ40*01 F, TRAJ41*01 F, TRAJ42*01 F, TRAJ43*01 F, TRAJ44*01 F, TRAJ45*01 F, TRAJ46*01 F, TRAJ47*01 F, TRAJ48*01 F, TRAJ49*01 F, TRAJ5*01 F, TRAJ50*01 F, TRAJ51*01 ORF, TRAJ52*01 F, TRAJ53*01 F, TRAJ54*01 F, TRAJ55*01 F, TRAJ56*01 F, TRAJ57*01 F, TRAJ58*01 F, TRAJ59*01 F, TRAJ6*01 F, TRAJ60*01 F, TRAJ61*01 F, TRAJ62*01 F, TRAJ63*01 F, TRAJ64*01 F, TRAJ65*01 F, TRAJ66*01 F, TRAJ67*01 F, TRAJ68*01 F, TRAJ69*01 F, TRAJ7*01 F, TRAJ70*01 F, TRAJ71*01 F, TRAJ72*01 F, TRAJ73*01 F, TRAJ74*01 F, TRAJ75*01 F, TRAJ76*01 F, TRAJ77*01 F, TRAJ78*01 F, TRAJ79*01 F, TRAJ8*01 F, TRAJ80*01 F, TRAJ81*01 F, TRAJ82*01 F, TRAJ83*01 F, TRAJ84*01 F, TRAJ85*01 F, TRAJ86*01 F, TRAJ87*01 F, TRAJ88*01 F, TRAJ89*01 F, TRAJ9*01 F, TRAJ90*01 F, TRAJ91*01 F, TRAJ91*02 F, TRAJ92*01 F, TRAJ92*02 F, TRAJ93*01 F, TRAJ93*02 F, TRAJ94*01 F, TRAJ94*02 F, TRAJ95*01 F, TRAJ96*01 ORF, TRAJ96*02 F, TRAJ97*01 F, TRAJ97*02 F, TRAJ98*01 F, TRAJ99*01 F.
- Addition of Danio rerio TRAC*01 F and TRAC*02 F.
- Addition of Danio rerio TRDC*01 F.
- Addition of 6 TRDD Danio rerio genes and alleles: TRDD1*01 F, TRDD2*01 F, TRDD3*01 F, TRDD4*01 F, TRDD5*01 F and TRDD6*01 F.
- Addition of Danio rerio TRDJ1*01 F and TRDJ2*01 F.
- Addition of 39 Canis lupus familiaris TRAV genes and 39 alleles: TRAV10*01 F, TRAV12*01 F, TRAV17*01 P, TRAV19*01 F, TRAV21*01 F, TRAV22*01 F, TRAV23*01 F, TRAV24*01 F, TRAV25*01 F, TRAV26*01 P, TRAV27*01 P, TRAV28*01 F, TRAV29*01 F, TRAV34*01 F, TRAV35*01 F, TRAV37*01 P, TRAV38-1*01 F, TRAV38-2*01 F, TRAV40*01 F, TRAV43-1*01 F, TRAV43-2*01 F, TRAV43-3*01 F, TRAV43-4*01 F, TRAV43-5*01 F, TRAV43-6*01 F, TRAV8-1*01 F, TRAV8-2*01 F, TRAV9-1*01 F, TRAV9-10*01 F, TRAV9-11*01 F, TRAV9-12*01 F, TRAV9-13*01 F, TRAV9-3*01 F, TRAV9-4*01 F, TRAV9-5*01 F, TRAV9-6*01 F, TRAV9-7*01 F, TRAV9-8*01 F, TRAV9-9*01 F.
- Addition of 52 Canis lupus familiaris TRAJ genes and 52 alleles: TRAC*01 F, TRAJ10*01 ORF, TRAJ11*01 ORF, TRAJ12*01 F, TRAJ13*01 F, TRAJ14*01 P, TRAJ15*01 F, TRAJ16*01 F, TRAJ18*01 F, TRAJ19*01 ORF, TRAJ2*01 F, TRAJ20*01 F, TRAJ21*01 F, TRAJ22*01 ORF, TRAJ23*01 F, TRAJ24*01 ORF, TRAJ25*01 F, TRAJ26*01 F, TRAJ27*01 F, TRAJ28*01 F, TRAJ3*01 F, TRAJ30*01 F, TRAJ31*01 F, TRAJ32*01 F, TRAJ33*01 F, TRAJ34*01 F, TRAJ37*01 F, TRAJ38*01 F, TRAJ39*01 F, TRAJ4*01 F, TRAJ40*01 F, TRAJ41*01 F, TRAJ42*01 F, TRAJ43*01 F, TRAJ44*01 F, TRAJ45*01 F, TRAJ46*01 ORF, TRAJ48*01 F, TRAJ49*01 F, TRAJ5*01 F, TRAJ50*01 F, TRAJ52*01 ORF, TRAJ53*01 ORF, TRAJ54*01 ORF, TRAJ56*01 F, TRAJ57*01 ORF, TRAJ58*01 F, TRAJ59*01 ORF, TRAJ6*01 F, TRAJ60*01 F, TRAJ7*01 ORF, TRAJ8*01 F, TRAJ9*01 F.
- Addition of 4 Canis lupus familiaris TRDV genes and 4 alleles :TRDV2*01 ORF, TRDV3*01 F, TRDV4*01 F and TRDV5*01 F.
- Addition of Canis lupus familiaris TRDC*01 F.
- Addition of 2 Canis lupus familiaris TRDD genes and 2 alleles: TRDD1*01 F and TRDD2*01 F.
- Addition of 4 Canis lupus familiaris TRDV genes and 4 alleles: TRDJ1*01 F, TRDJ2*01 F, TRDJ3*01 ORF and TRDJ4*01 F.
01 September 2017
- Addition of Canis lupus familiaris TRBV4-4.
09 February 2017
- Addition of Mus musculus VPREB1*01 F and VPREB2*01 F genes and alleles.
08 February 2017
- Addition of Mus musculus IGLL1*01 F and IGLL1*02 (P) genes and alleles.
03 February 2017
- Addition of 5 Homo sapiens genes: IGLL1, IGLL2, IGLL3, IGLL4, IGLL5
  and 12 alleles: IGLL1*01 F, IGLL1*02 F, IGLL1*03 F, IGLL1*04 F, IGLL2*01 P, IGLL2*02 P, IGLL3*01 F, IGLL4*01 P, IGLL5*01 F, IGLL5*02.
02 February 2017
- Addition of Macaca fascicularis IGHA*02 and IGHA*03 genes and alleles.
- The functionality of Macaca fascicularis IGHV3S14*01 is ORF.
17 January 2017
- Update of Macaca fascicularis IGHG1 alleles and reference sequences:
  - IGHG1*01 reference sequence is Macfas_2_Chr7.
  - IGHG1*02 reference sequence is AF045536.
  - IGHG1*03 reference sequence is CS101552.
  - IGHG1*04 reference sequence is JQ868728.
  - IGHG1*05 reference sequence is L13307.
12 January 2017
- Addition of Macaca fascicularis IGHM*01 gene and allele.
8 December 2016
- Addition of the UniProt cross-references for the 107 human IG variable genes:
  IGLV4-69, IGLV8-61, IGLV4-60, IGLV10-54, IGLV7-46, IGLV5-37, IGLV3-22, IGLV2-18, IGLV3-16, IGLV3-12, IGLV3-10, IGLV4-3, IGKV2-28, IGHV3-64, IGHV4-4, IGKV2D-29, IGKV1D-17, IGKV1-27, IGKV2D-30, IGLV5-45, IGKV3D-15, IGKV1D-8, IGKV2-40, IGKV2D-26, IGKV3D-11, IGLV5-52, IGHV1-45, IGHV3-49, IGKV6D-21, IGLV1-36, IGHV6-1, IGHV3-15, IGHV3-21, IGHV2-26, IGHV3-73, IGHV3-74, IGHV3-43, IGLV9-49, IGHV3-72, IGKV1D-43, IGKV1D-13, IGKV6-21, IGKV3D-20, IGHV1-3, IGHV1-18, IGHV1-24, IGHV4-28, IGHV5-51, IGHV1-58, IGHV4-61, IGHV3-66, IGKV3D-7, IGKV1-8, IGKV2-24, IGKV1-9, IGKV1-6, IGKV1-12, IGLV5-39, IGKV1D-33, IGKV1-33, IGKV1-39, IGKV1-17, IGKV1D-16, IGKV1-5, IGKV1D-12, IGKV2D-40, IGKV2D-28, IGKV3-20, IGKV3-15, IGLV1-44, IGLV1-47, IGLV1-51, IGLV1-40, IGLV2-14, IGLV2-23, IGLV2-11, IGLV2-8, IGLV3-19, IGLV3-1, IGLV3-25, IGLV3-27, IGLV6-57, IGHV1-69, IGHV1-46, IGHV3-11, IGHV3-48, IGHV3-23, IGHV3-13, IGHV3-53, IGHV3-30, IGHV3-33, IGHV3-7, IGHV3-9, IGHV2-70, IGHV2-5, IGHV4-39, IGHV4-59, IGLV7-43, IGKV1-16, IGKV1D-39, IGKV3-11, IGKV2-30, IGKV4-1, IGKV5-2, IGHV4-34, IGHV1-2, IGLV3-21.
7 December 2016
- Removal of the gene and allele Macaca fascicularis IGHV(II)S16*01.
1 December 2016
- Addition of a new species: Crab-eating macaque (Macaca fascicularis)
  - Addition of 150 IGHV genes and alleles (62 F, 7 ORF, 81 P): IGHV(I)S1*01 P, IGHV(I)S2*01 P, IGHV(I)S3*01 P, IGHV(I)S4*01 P ,IGHV(II)S1*01 P, IGHV(II)S10*01 P, IGHV(II)S11*01 P, IGHV(II)S12*01 P ,IGHV(II)S13*01 P, IGHV(II)S14*01 P, IGHV(II)S15*01 P, IGHV(II)S16*01 ORF, IGHV(II)S17*01 P, IGHV(II)S2*01 P, IGHV(II)S3*01 P, IGHV(II)S4*01 P, IGHV(II)S5*01 P, IGHV(II)S6*01 P, IGHV(II)S7*01 P, IGHV(II)S8*01 P, IGHV(II)S9*01 P, IGHV(III)S1*01 P, IGHV(III)S10*01 P, IGHV(III)S11*01 P, IGHV(III)S12*01 P, IGHV(III)S13*01 P, IGHV(III)S2*01 P, IGHV(III)S3*01 P, IGHV(III)S4*01 P, IGHV(III)S5*01 P, IGHV(III)S6*01 P, IGHV(III)S7*01 P, IGHV(III)S8*01 P, IGHV(III)S9*01 P, IGHV1-1*01 F, IGHV1S1*01 F, IGHV1S10*01 F, IGHV1S11*01 P, IGHV1S12*01 P, IGHV1S13*01 P, IGHV1S14*01 P, IGHV1S2*01 F, IGHV1S3*01 P, IGHV1S4*01 P, IGHV1S5*01 P, IGHV1S6*01 P, IGHV1S7*01 P, IGHV1S8*01 P, IGHV1S9*01 F, IGHV2-1*01 F, IGHV2S1*01 F, IGHV2S2*01 F, IGHV2S3*01 P, IGHV3-10*01 F, IGHV3-11*01 F, IGHV3-12*01 F, IGHV3-14*01 F, IGHV3-20*01 F, IGHV3-21*01 ORF, IGHV3-22*01 F, IGHV3-24*01 P, IGHV3-5*01 ORF, IGHV3-6*01 F, IGHV3-7*01 F, IGHV3-9*01 F, IGHV3S1*01 P, IGHV3S10*01 F, IGHV3S11*01 F, IGHV3S12*01 P, IGHV3S13*01 P, IGHV3S14*01 P, IGHV3S15*01 F, IGHV3S16*01 F, IGHV3S17*01 F, IGHV3S18*01 F, IGHV3S19*01 F, IGHV3S2*01 P, IGHV3S20*01 F, IGHV3S21*01 F, IGHV3S22*01 F, IGHV3S23*01 F, IGHV3S24*01 P, IGHV3S25*01 F, IGHV3S26*01 F, IGHV3S27*01 P, IGHV3S28*01 P, IGHV3S29*01 F, IGHV3S3*01 P, IGHV3S30*01 F, IGHV3S31*01 P, IGHV3S32*01 F, IGHV3S33*01 P, IGHV3S34*01 P, IGHV3S35*01 F, IGHV3S36*01 P, IGHV3S37*01 P, IGHV3S38*01 P, IGHV3S39*01 P, IGHV3S4*01 F, IGHV3S40*01 F, IGHV3S41*01 F, IGHV3S42*01 P, IGHV3S43*01 F, IGHV3S44*01 F, IGHV3S45*01 F, IGHV3S46*01 F, IGHV3S47*01 P, IGHV3S48*01 ORF, IGHV3S49*01 P, IGHV3S5*01 F, IGHV3S50*01 P, IGHV3S51*01 P, IGHV3S52*01 P, IGHV3S53*01 P, IGHV3S6*01 P, IGHV3S7*01 P, IGHV3S8*01 P, IGHV3S9*01 ORF, IGHV4-2*01 F, IGHV4S1*01 P, IGHV4S10*01 F, IGHV4S11*01 F, IGHV4S12*01 F, IGHV4S13*01 F, IGHV4S14*01 F, IGHV4S15*01 F, IGHV4S16*01 F, IGHV4S17*01 F, IGHV4S18*01 F, IGHV4S19*01 F, IGHV4S2*01 ORF, IGHV4S2-2*01 P, IGHV4S4*01 P, IGHV4S5*01 F, IGHV4S6*01 F, IGHV4S7*01 F, IGHV4S8*01 P, IGHV4S9*01 F, IGHV5-1*01 ORF, IGHV5-2*01 F, IGHV5S1*01 F, IGHV6-1*01 F, IGHV7-1*01 F, IGHV7S1*01 F, IGHV7S2*01 P, IGHV7S3*01 P, IGHV7S5*01 P, IGHV7S6*01 P, IGHV7S7*01 P, IGHV7S9*01 P.
  - Addition of 8 IGHJ genes and alleles (6 F, 1 ORF, 1P): IGHJ1*01 F, IGHJ2*01 ORF, IGHJ3*01 F, IGHJ3P*01 P, IGHJ4*01 F, IGHJ5-1*01 F, IGHJ5-2*01 F, IGHJ6*01 F.
  - Addition of 40 IGHD genes and alleles (25 F, 15 ORF): IGHD1S1*01 ORF, IGHD1S10*01 F, IGHD1S16*01 F, IGHD1S21*01 ORF, IGHD1S27*01 ORF, IGHD1S33*01 ORF, IGHD1S39*01 F, IGHD1S5*01 F, IGHD2S11*01 F, IGHD2S17*01 F, IGHD2S2*01 ORF, IGHD2S22*01 F, IGHD2S28*01 F, IGHD2S34*01 F, IGHD3S12*01 ORF, IGHD3S18*01 F, IGHD3S23*01 ORF, IGHD3S29*01 F, IGHD3S35*01 ORF, IGHD3S6*01 F, IGHD4S13*01 ORF, IGHD4S19*01 ORF, IGHD4S24*01 F, IGHD4S30*01 F, IGHD4S36*01 F, IGHD4S7*01 ORF, IGHD5S14*01 ORF, IGHD5S25*01 ORF, IGHD5S3*01 ORF, IGHD5S31*01 F, IGHD5S37*01 F, IGHD5S8*01 F, IGHD6S15*01 ORF, IGHD6S20*01 F, IGHD6S26*01 F, IGHD6S32*01 F, IGHD6S38*01 F, IGHD6S4*01 F, IGHD6S9*01 F, IGHD7S40*01 F.
  - Addition of IGHD*01 constant gene and allele (ORF).
30 September 2016
- Removal of the allele Homo sapiens IGHV3-23D*02.
- Addition of the pseudogene Homo sapiens IGHV(III)-22-2D*01 gene and allele.
- The Homo sapiens IGHV(II)-23-2*01 gene and allele is renamed as IGHV(II)-22-1D*01.
05 July 2016
- The functionality of Ovis aries TRAV44S1*01 is F.
- The functionality of Ovis aries TRDV1S6*01 is F.
15 June 2016
- AC245166 is reference sequence for Homo sapiens IGHV(II)-23-2*01, IGHV(II)-26-2*01, IGHV(II)-30-21*01 and IGHV(II)-33-1*01.
14 June 2016
- The functionality of Rattus norvegicus IGHV1-18*01 is F.
23 May 2016
- Mus musculus IGHV5S4*02 has been assigned to Mus musculus IGHV5-9-2*01 F.
- Mus musculus IGHV5S9*01 has been assigned to Mus musculus IGHV5-9-1*01 F.
20 May 2016
- Deletion of 9 human (Homo sapiens) pseudogenes: IGHV(II)-30-43, IGHV(II)-30-31, IGHV(II)-44-3, IGHV(II)-44-2D, IGHV(II)-44-1D IGHV(II)-28-2, IGHV(II)-23-1, IGHV(II)-20-3, IGHV(III)-20-2.
28 April 2016
- The functionality of mouse (Mus musculus) IGHV1-67-1*01 is P (no INIT-CODON in the L-PART1).
27 April 2016
- The functionality of mouse (Mus musculus) IGHV16-1*01 is ORF because of no CONSERVED-TRP.
31 March 2016
- Addition of the Alpaca (Vicugna pacos) IGHC genes and alleles: IGHA*01, IGHD*01, IGHE*01, IGHG1A*01, IGHG1B*01, IGHG2B*01, IGHG2C*01, IGHM*01.
23 March 2016
- Addition of the Rat (Rattus norvegicus strain: BN; Sprague-Dawley) IGH gene positions in the in Rn_Celera (NCBI) Alternate Assembly.
21 March 2016
- Addition of 1 Sheep (Ovis aries) TRAV and TRDV genes and alleles (1 P):TRAV23S4*01 P.
16 March 2016
- Addition of 6 Sheep (Ovis aries) TRAV and TRDV genes and alleles (2 F, 4 P): TRDV2S2*01 F, TRDV1S7*01 P, TRAV34-1*01 P, TRAV6-1*01 P, TRAV4-1*01 F, TRAV42S2*01 P.
15 March 2016
- Addition of 16 Sheep (Ovis aries) TRAV and TRDV genes and alleles (10 F, 2 ORF, 4 P): TRAV44S1*01 ORF, TRAV44S6*01 F, TRAV44S7*01 P, TRAV45S5*01 F, TRAV45S2*01 F, TRAV3-1*01 F, TRDV1S9*01 P, TRDV1S12*01 F, TRDV1S15*01 P, TRDV1S16*01 F, TRDV1S20*01 F, TRDV1S21*01 ORF, TRDV1S22*01 F, TRDV1S26*01 P, TRAV3S4*01 F, TRAV45S1*01 F.
14 March 2016
- Addition of 25 Sheep (Ovis aries) TRAV and TRDV genes and alleles (18 F, 2 ORF, 5 P): TRDV2-1*01 F, TRDV3-1*01 F, TRDV4-1*01 F, TRAV1-1*01 F, TRAV2-1*01 ORF, TRAV5-1*01 F, TRAV8-1*01 P, TRAV10-1*01 F, TRAV12-1*01 F, TRAV13-1*01 F, TRAV16S1*01 F, TRAV17-1*01 F, TRAV21-1*01 F, TRAV27-1*01 F, TRAV35-1*01 P, TRAV36-1*01 P, TRAV37-1*01 P, TRAV38-1*01 F, TRAV39-1*01 ORF, TRAV41-1*01 F, TRAV45S3*01 F, TRAV45S4*01 F, TRAV18S2*01 F, TRAV18S1*01 F, TRAV22S7*01 P.
10 March 2016
- Addition of 51 Sheep (Ovis aries) TRAV genes and alleles (38 F, 3 ORF, 10 P): TRAV9S1*01 P, TRAV9S2*01 F, TRAV9S3*01 F, TRAV9S4*01 F, TRAV14S1*01 ORF, TRAV14S2*01 F, TRAV25S1*01 P, TRAV25S2*01 F, TRAV29S1*01 F, TRAV29S2*01 F, TRAV42S1*01 ORF, TRAV42S3*01 P, TRDV1S1*01 F, TRDV1S2*01 F, TRDV1S3*01 F, TRDV1S4*01 P, TRDV1S5*01 F, TRDV1S6*01 P, TRDV1S8*01 F, TRDV1S10*01 F, TRDV1S11*01 F, TRDV1S13*01 F, TRDV1S14*01 F, TRDV1S17*01 F, TRDV1S18*01 F, TRDV1S19*01 F, TRDV1S23*01 F, TRDV1S24*01 F, TRDV1S25*01 F, TRAV23S1*01 P, TRAV23S2*01 P, TRAV23S5*01 P, TRAV22S1*01 P, TRAV22S2*01 F, TRAV22S3*01 F, TRAV22S4*01 P, TRAV22S5*01 ORF, TRAV22S6*01 F, TRAV26S1*01 F, TRAV26S2*01 F, TRAV28S1*01 F, TRAV28S2*01 F, TRAV43S1*01 PF, TRAV43S2*01 F, TRAV43S3*01 F, TRAV43S4*01 F, TRAV43S5*01 F, TRAV44S2*01 F, TRAV44S3*01 F, TRAV44S4*01 P, TRAV44S5*01 F.
8 March 2016
- Addition of the Sheep (Ovis aries) TRAC*01 F and TRDC*01 F genes and alleles (2 F).
- Addition of 61 TRAJ genes and alleles (57 F, 2 ORF, 2P): TRAJ1*01 F, TRAJ10*01 F, TRAJ11*01 F, TRAJ12*01 F, TRAJ13*01 F, TRAJ14*01 F, TRAJ15*01 ORF, TRAJ16*01 F, TRAJ17*01 F, TRAJ18*01 F, TRAJ19*01 F, TRAJ2*01 F, TRAJ20*01 F, TRAJ21*01 F, TRAJ22*01 F, TRAJ23*01 F, TRAJ24*01 F, TRAJ25*01 F, TRAJ26*01 F, TRAJ27*01 F, TRAJ28*01 F, TRAJ29*01 F, TRAJ3*01 F, TRAJ30*01 F, TRAJ31*01 F, TRAJ32*01 F, TRAJ33*01 F, TRAJ34*01 F, TRAJ35*01 F, TRAJ36*01 F, TRAJ37*01 F, TRAJ38*01 F, TRAJ39*01 F, TRAJ4*01 F, TRAJ40*01 F, TRAJ41*01 F, TRAJ42*01 F, TRAJ43*01 F, TRAJ44*01 F, TRAJ45*01 F, TRAJ46*01 F, TRAJ47*01 F, TRAJ48*01 F, TRAJ49*01 F, TRAJ5*01 F, TRAJ50*01 F, TRAJ51*01 F, TRAJ52*01 P, TRAJ53*01 F, TRAJ54*01 F, TRAJ55*01 F, TRAJ56*01 F, TRAJ57*01 F, TRAJ58*01 F, TRAJ59*01 F, TRAJ6*01 ORF, TRAJ60*01 F, TRAJ61*01 P, TRAJ7*01 F, TRAJ8*01 F, TRAJ9*01 F.
- Addition of 4 TRDJ genes and alleles (3 F, 1 ORF): TRDJ1-1*01 F, TRDJ1-2*01 F, TRDJ1-3*01 ORF, TRDJ1-4*01 F.
- Addition of 7 TRDD genes and alleles (7 F): TRDD1*01 F, TRDD2*01 F, TRDD3*01 F, TRDD4*01 F, TRDD5*01 F, TRDD6*01 F, TRDD7*01 F.
3 March 2016
- Addition of 4 Alpaca (Vicugna pacos) IGHV pseudogenes with frameshifts: IGHV3S49*01, IGHV3S50*01, IGHV3S51*01 and IGHV3S52*01.
22 February 2016
- Addition of a new species: Alpaca (Vicugna pacos):
  - Addition of 84 IGHV genes and alleles (73 F, 1 ORF, 10 P): IGHV1-1*01 F, IGHV1S2*01 F, IGHV1S3*01 F, IGHV1S4*01 F, IGHV1S5*01 P, IGHV1S6*01 F, IGHV2S1*01 F, IGHV2S10*01 F, IGHV2S11*01 P, IGHV2S2*01 F, IGHV2S3*01 F, IGHV2S4*01 F, IGHV2S5*01 F, IGHV2S6*01 F, IGHV2S7*01 F, IGHV2S8*01 F, IGHV2S9*01 P, IGHV3-1*01 F, IGHV3-2*01 F, IGHV3-3*01 F, IGHV3S1*01 F, IGHV3S10*01 F, IGHV3S11*01 F, IGHV3S12*01 F, IGHV3S13*01 F, IGHV3S14*01 F, IGHV3S15*01 F, IGHV3S16*01 F, IGHV3S17*01 F, IGHV3S18*01 F, IGHV3S19*01 P, IGHV3S2*01 F, IGHV3S20*01 F, IGHV3S21*01 P, IGHV3S22*01 P, IGHV3S23*01 P, IGHV3S24*01 P, IGHV3S25*01 F, IGHV3S26*01 F, IGHV3S27*01 F, IGHV3S28*01 F, IGHV3S29*01 F, IGHV3S3*01 ORF, IGHV3S30*01 F, IGHV3S31*01 F, IGHV3S32*01 F, IGHV3S33*01 F, IGHV3S34*01 F, IGHV3S35*01 F, IGHV3S36*01 F, IGHV3S37*01 F, IGHV3S38*01 F, IGHV3S39*01 F, IGHV3S4*01 F, IGHV3S40*01 F, IGHV3S41*01 F, IGHV3S42*01 F, IGHV3S43*01 F, IGHV3S44*01 F, IGHV3S45*01 F, IGHV3S46*01 F, IGHV3S47*01 P, IGHV3S48*01 P, IGHV3S5*01 F, IGHV3S53*01 F, IGHV3S54*01 F, IGHV3S55*01 F, IGHV3S56*01 F, IGHV3S57*01 F, IGHV3S58*01 F, IGHV3S59*01 F, IGHV3S6*01 F, IGHV3S60*01 F, IGHV3S61*01 F, IGHV3S62*01 F, IGHV3S63*01 F, IGHV3S64*01 F, IGHV3S65*01 F, IGHV3S66*01 F, IGHV3S67*01 F, IGHV3S68*01 F, IGHV3S7*01 F, IGHV3S8*01 F, IGHV3S9*01 F.
19 February 2016
- Addition of a new species: Alpaca (Vicugna pacos):
  - Addition of 7 IGHJ genes and alleles (6 F, 1 ORF): IGHJ1*01 ORF, IGHJ2*01 F, IGHJ3*01 F, IGHJ4*01 F, IGHJ5*01 F, IGHJ6*01 F, IGHJ7*01 F.
  - Addition of 8 IGHD genes and alleles (8 F): IGHD1*01 F, IGHD2*01 F, IGHD3*01 F, IGHD4*01 F, IGHD5*01 F, IGHD6*01 F, IGHD7*01 F, IGHD8*01 F.
9 February 2016
- Addition of Sus scrofa IGKV3-1*01 P and IGKV7-2*01 P.

8 February 2016

Update of Mus musculus IGHD gene and allele names and functionalities:

Old Mus musculus IGHD name and allele	Old functionaliy	New Mus musculus IGHD name and allele	New functionality
IGHD5-7*01	ORF	IGHD6-3*01	F
IGHD5-8*01	ORF	IGHD6-4*01	F
IGHD6-1*01	P	IGHD6-1*02	F
IGHD6-1*02	P	IGHD6-1*01	F
IGHD6-2*01	P	IGHD6-2*02	F
IGHD6-2*02	P	IGHD6-1*01	F

1 February 2016
- The functionality of Rattus norvegicus IGHD2-1*01 is F.
- The functionality of Rattus norvegicus IGHD2-2*01 is F.
- The functionality of Rattus norvegicus IGHD3-1*01 is F.
- The functionality of Rattus norvegicus IGHD3-8*01 is F.
- The functionality of Rattus norvegicus IGHD4-6*01 is F.
19 January 2016
- The functionality of Rattus norvegicus IGHV8-28*01 is F (reference sequence AABR03049296).

15 December 2015

Update of the Rattus norvegicus IGHD gene nomenclature according to the chromosome 6 genomic scaffold alternate assembly Rn_Celera 342000077095705:

Update of IGHD gene names:

Old Rattus norvegicus IGHD name	New Rattus norvegicus IGHD name
IGHD1-5*01	IGHD1-10*01
IGHD1-1*01	IGHD1-6*01
IGHD1-2*01	IGHD1-7*01
IGHD1-3*01	IGHD1-8*01
IGHD1-4*01	IGHD1-9*01
IGHD2-1*01	IGHD2-5*01
IGHD2-2*01	IGHD2-6*01
IGHD2-3*01	IGHD2-8*01
IGHD3-1*01	IGHD3-4*01
IGHD3-2*01	IGHD3-5*01
IGHD3-4*01	IGHD3-7*01
IGHD4-1*01	IGHD4-3*01
IGHD4-2*01	IGHD4-4*01
IGHD1-6*01	IGHD1-11*01
IGHD3-3*01	IGHD3-8*01
IGHD4-3*01	IGHD4-5*01
IGHD4-4*01	IGHD4-6*01
IGHD5-1*01	IGHD5-1*01
IGHD1-8*01	IGHD1-12*03
IGHD1-7*01	IGHD1-12*02

Addition of 17 IGHD genes and alleles: IGHD1-12*01 F, IGHD3-6*01 ORF, IGHD2-7*01 F, IGHD3-3*01 F, IGHD2-4*01 ORF, IGHD1-5*01 ORF, IGHD1-4*01 ORF, IGHD3-2*01 F, IGHD2-3*01 ORF, IGHD1-3*01 ORF, IGHD4-2*01 ORF, IGHD2-2*01 ORF, IGHD1-2*01 F, IGHD4-1*01 ORF, IGHD3-1*01 ORF, IGHD2-1*01 ORF, IGHD1-1*01 ORF.

21 December 2015
- Update of the Rattus norvegicus IGHC reference directory according to the chromosome 6 genomic scaffold alternate assembly Rn_Celera 342000077108320:
  - Rattus norvegicus IGHA*01: the reference sequence is RatNor_6_chr6 (AABR03049801 becomes sequence from the literature).
  - Rattus norvegicus IGHD*01: the reference sequence is RatNor_6_chr6 (AABR03049259 becomes sequence from the literature).
  - Rattus norvegicus IGHE*02: the reference sequence is RatNor_6_chr6 (AABR03049801 becomes sequence from the literature).
  - Rattus norvegicus IGHG1*01: the reference sequence is RatNor_6_chr6 (AABR03048905 becomes sequence from the literature).
  - Rattus norvegicus IGHG2A*01: the reference sequence is RatNor_6_chr6 (AABR03049560 becomes sequence from the literature).
  - Rattus norvegicus IGHG2B*01: the reference sequence is RatNor_6_chr6 (AABR03048905 becomes sequence from the literature).
  - Rattus norvegicus IGHG2C*01: the reference sequence is RatNor_6_chr6 (AABR03049912 becomes sequence from the literature).
  - Rattus norvegicus IGHM*01: the reference sequence is RatNor_6_chr6 (AABR03049259 becomes sequence from the literature).
27 November 2015
- Update of the Rattus norvegicus IGHV reference directory according to the chromosome 6 genomic scaffold alternate assembly Rn_Celera 342000077095705:
  - Addition of 60 new genes and alleles: IGHV1-19*01 P, IGHV1-54*01 P, IGHV1-67*01 P, IGHV1-8*01 F, IGHV2-11*01 P, IGHV2-12*01 P, IGHV2-16*01 ORF, IGHV2-17*01 P, IGHV2-20*01 P, IGHV2-28*01 P, IGHV2-31*01 P, IGHV2-42*01 P, IGHV2-49*01 P, IGHV2-50*01 P, IGHV2-53*01 ORF, IGHV2-54*01 P, IGHV2-55*01 ORF, IGHV2-56*01 P, IGHV2-61*01 F, IGHV2-69*01 P, IGHV2-74*01 P, IGHV2-9*01 P, IGHV5-1*01 P, IGHV5-11*01 P, IGHV5-13*01 P, IGHV5-14*01 P, IGHV5-16*01 P, IGHV5-25*01 F, IGHV5-3*01 P, IGHV5-35*01 F, IGHV5-39*01 P, IGHV5-41*01 P, IGHV5-42*01 P, IGHV5-43*01 F, IGHV5-53*01 P, IGHV5-64*01 P, IGHV5-65*01 P, IGHV5-8*01 P, IGHV6-16*01 P, IGHV6-17*01 P, IGHV6-2*01 P, IGHV6-9*01 P, IGHV7-5*01 P, IGHV8-10*01 P, IGHV8-11*01 P, IGHV8-12*01 P, IGHV8-13*01 P, IGHV8-18*01 P, IGHV8-19*01 P, IGHV8-2*01 P, IGHV8-24*01 ORF, IGHV8-30*01 ORF, IGHV8-31*01 F, IGHV8-4*01 P, IGHV8-6*01 P, IGHV8-7*01 P, IGHV8-8*01 P, IGHV8-9*01 P, IGHV9-10*01 P, IGHV9-3*01 ORF, IGHV9-9*01 P.
  - Definition of IMGT definitive the nomenclature for 278 genes: see the correspondance between the definitive IMGT gene and allele name and the provisional one.

Major updates before 2014

28 November 2013
- The definitive IMGT gene name Homo sapiens IGHV1-69-2 has been assigned to IGHV1-f owing to its localization in AC245023 and AC245094 [Watson C.T. et al., Am. J. Hum. Genet., 92, 1-17 (2013)].
- The definitive IMGT gene name Homo sapiens IGHV1-38-4 has been assigned to IGHV1-c owing to its localization in AC241995 and AC234225 [Watson C.T. et al., Am. J. Hum. Genet., 92, 1-17 (2013)].
- The definitive IMGT gene name Homo sapiens IGHV3-38-3 has been assigned to IGHV3-d owing to its localization in AC241995 and AC234225 [Watson C.T. et al., Am. J. Hum. Genet., 92, 1-17 (2013)].
- The definitive IMGT gene name Homo sapiens IGHV3-71 (allele IGHV3-71*01) has been assigned to IGHV3-g.
23 October 2013
- The definitive IMGT gene name Homo sapiens IGHV3-69-1 has been assigned to IGHV3-h owing to its localization in AC245023 and AC245094 [Watson C.T. et al., Am. J. Hum. Genet., 92, 1-17 (2013)].
- The definitive IMGT gene name Homo sapiens IGHV4-38-2 has been assigned to IGHV4-b owing to its localization in AC233755 and KC162926 [Watson C.T. et al., Am. J. Hum. Genet., 92, 1-17 (2013)].
15 November 2012
- Entry of Homo sapiens RPI MH1Like Alpha MICA gene.
1 June 2012
- Entry of Oncorhynchus mykiss MH genes.
16 April 2012
- The IMGT/GENE-DB reference sequences of the D-REGION of D genes in amino acid are provided in the three reading frames.
- The FASTA header of IMGT/GENE-DB reference sequences has been updated:
  - Field 6. may be modified if:
    - a nucleotide has been added in 5' of a label, to obtain a complete first codon (for example for C-GENE exons if splicing frame 1 or 2): the added nucleotide is indicated followed by a comma before the start position.
      See for example the reference sequences of Homo sapiens IGHA1 gene .
      Note the number of added nucleotides in 5' is indicated in field 9.
    - a nucleotide has been deleted in 3' of a label, to obtain a complete last codon (for example for C-GENE exons if splicing frame 1 or 2): the end position is decreased by the number of deleted nucleotides in 3'.
      See for example the reference sequences of Homo sapiens IGHA1 gene .
      Note the number of removed nucleotides in 3' is indicated in field 10.
    - a nucleotide has been added in 3' of a label, to obtain the complete genomic sequence (for example for J-REGION reference sequence from cDNA): the end position is followed by a comma and the added nucleotides in 3'.
      See for example the reference sequences of Homo sapiens TRAJ47*02 allele .
      Note the number of added nucleotides in 3' is indicated in field 10.
  - Field 9. +n : number of nucleotides (nt) added in 5' compared to the corresponding label extracted from IMGT/LIGM-DB.
  - Field 10. +n or -n: number of nucleotides (nt) added or removed in 3' compared to the corresponding label extracted from IMGT/LIGM-DB.
22 February 2012
- Addition of 72 Macaca mulatta TRBV genes and alleles: TRBV1-1*01, TRBV1-2*01, TRBV1-3*01, TRBV10-1*01, TRBV10-2*01, TRBV10-3*01, TRBV11-1*01, TRBV11-2*01, TRBV11-3*01, TRBV12-1*01, TRBV12-2*01, TRBV12-3*01, TRBV12-4*01, TRBV13*01, TRBV14*01, TRBV15*01, TRBV16*01, TRBV18*01, TRBV19*01, TRBV2-1*01, TRBV2-2*01, TRBV2-3*01, TRBV20-1*01, TRBV21-1*01, TRBV22-1*01, TRBV23-1*01, TRBV24-1*01, TRBV25-1*01, TRBV27*01, TRBV28*01, TRBV29*01, TRBV3-1*01, TRBV3-2*01, TRBV3-3*01, TRBV3-4*01, TRBV30*01, TRBV4-1*01, TRBV4-2*01, TRBV4-3*01, TRBV5-1*01, TRBV5-10*01, TRBV5-2*01, TRBV5-3*01, TRBV5-4*01, TRBV5-5*01, TRBV5-6*01, TRBV5-7*01, TRBV5-8*01, TRBV5-9*01, TRBV6-1*01, TRBV6-2*01, TRBV6-3*01, TRBV6-4*01, TRBV6-5*01, TRBV6-6*01, TRBV6-7*01, TRBV6-8*01, TRBV7-10*01, TRBV7-1*01, TRBV7-2*01, TRBV7-3*01, TRBV7-4*01, TRBV7-5*01, TRBV7-6*01, TRBV7-7*01, TRBV7-8*01, TRBV7-9*01, TRBV8-1*01, TRBV9-1*01, TRBV26*01, TRBVA*01, TRBVB*01.
- Addition of 2 Macaca mulatta TRBD genes and alleles: TRBD1*01, TRBD2*01.
- Addition of 14 Macaca mulatta TRBJ genes and 17 alleles: TRBJ1-1*01, TRBJ1-2*01, TRBJ1-3*01, TRBJ1-4*01, TRBJ1-5*01, TRBJ1-6*01, TRBJ1-6*02, TRBJ2-1*01, TRBJ2-1*02, TRBJ2-2*01, TRBJ2-2P*01, TRBJ2-2P*02, TRBJ2-3*01, TRBJ2-4*01, TRBJ2-5*01, TRBJ2-6*01, TRBJ2-7*01.
- Addition of 2 Macaca mulatta TRBC genes and alleles: TRBC1*01, TRBC2*01.
19 January 2012
- Update of the external links to VEGA.
30 September 2011
- Addition of 38 Bos taurus TRGV genes and alleles: TRGV1-1*01, TRGV1-1*02, TRGV1-1*03, TRGV2-1*01, TRGV3-1*01, TRGV3-1*02, TRGV3-2*01, TRGV3-2*02, TRGV4-1*01, TRGV5-1*01, TRGV5-1*02, TRGV5-1*03, TRGV5-1*04, TRGV5-1*05, TRGV5-2*01, TRGV5-2*02, TRGV5-2*03, TRGV5-2*04, TRGV5-2*05, TRGV5-2*06, TRGV5-2*07, TRGV5-2*08, TRGV5-2*09, TRGV5-2*10, TRGV6-1*01, TRGV6-1*02, TRGV6-2*01, TRGV7-1*01, TRGV7-1*02, TRGV8-1*01, TRGV8-2*01, TRGV8-2*02, TRGV8-3*01, TRGV8-3*02, TRGV8-4*01, TRGV9-1*01, TRGV9-2*01, TRGV10-1*01.
- and 16 TRGJ 16 genes and alleles: TRGJ1-1*01, TRGJ1-2*01, TRGJ1-2*02, TRGJ1-2*03, TRGJ2-1*01, TRGJ2-1*02, TRGJ2-1*03, TRGJ2-2*01, TRGJ2-2*02, TRGJ2-2*03, TRGJ3-1*01, TRGJ3-1*02, TRGJ4-1*01, TRGJ4-2*01, TRGJ5-1*01, TRGJ6-1*01.
14 April 2011
- Addition of cross-references to NCBI Gene entries for mouse IG and TR genes in the IMGT/GENE-DB entries (in the 'External links' section).
25 February 2011
- Addition of the Homo sapiens IGHV3-NL1 gene and 31 Homo sapiens IGHV alleles sequenced from Papua (New Guinea): IGHV1-2*05, IGHV3-21*03, IGHV3/OR16-10*03, IGHV1-8*02, IGHV1-18*03, IGHV3-7*03, IGHV3-9*02, IGHV3-11*04, IGHV3-13*04, IGHV3-21*04, IGHV3-25*04, IGHV3-33*06, IGHV3-48*04, IGHV3-53*04, IGHV3-NL1*01, IGHV4-28*06, IGHV4-30-2*05, IGHV7-4-1*04, IGHV7-4-1*05, IGHV1/OR15-1*03, IGHV1/OR15-1*04, IGHV1/OR15-2*02, IGHV1/OR15-2*03, IGHV3/OR15-7*05, IGHV3/OR16-6*02, IGHV3/OR16-8*02, IGHV3-25*05, IGHV3-71*02, IGHV3-71*03, IGHV4/OR15-8*03, IGHV7-34-1*02.
24 February 2011
- Addition of 13 Mus musculus IGHV genes and 13 Mus musculus IGHV alleles: IGHV(I)-1, IGHV(II)-1, IGHV(II)-2, IGHV(II)-3, IGHV(II)-4, IGHV(II)-5, IGHV(III)-1, ICHV(III)-2, IGHV(III)-3, IGHV(III)-4, IGHV(III)-5, IGHV(III)-6, IGHV(III)-7.
25 January 2011
- Addition of 13 Camelus dromedarius IGHV genes and 13 Camelus dromedarius IGHV alleles: TRDV1S1, TRDV1S1, TRDV1S2, TRDV1S2, TRDV1S3, TRDV1S4, TRDV1S4, TRDV1S5, TRDV1S6, TRDV2S1, TRDV2S2, TRDV2S3, TRDV4S1.
7 December 2010
- Addition of the Homo sapiens IGKV1/OR2-118*01 genes and IGKV2/OR2-7D*01 and alleles.
16 September - 19 October 2010
- Addition of 34 Mus musculus TRAV genes and 56 alleles resulting from the expertise of the triplicated zone of the TRAV locus in the Mus musculus C57BL/6J strain: TRAV14D-2*03, TRAV3D-3*02, TRAV9D-4*05, TRAV5D-4*05, TRAV6D-7*04, TRAV7D-6*02, TRAV13D-3*02, TRAV8D-2*03, TRAV16D/DV11*04, TRAV13D-4*03, TRAV14D-3/DV8*08, TRAV7N-4*01, TRAV9N-1*01, TRAV15D-3*02, TRAV6N-5*01, TRAV10N*01, TRAV6N-6*01, TRAV11N*01, TRAV7N-5*01, TRAV12N-1*01, TRAV13N-1*01, TRAV14N-1*01, TRAV15N-1*01, TRAV3N-2*01, TRAV9N-2*01, TRAV4N-3*01,TRAV5N-2*01, TRAV12N-2*01, TRAV9N-3*01, TRAV5N-3*01, TRAV12N-3*01, TRAV13N-2*01, TRAV14N-2*01, TRAV15N-2*01, TRAV3N-3*01, TRAV9N-4*01, TRAV4N-4*01, TRAV5N-4*01, TRAV6N-7*01, TRAV7N-6*01, TRAV13N-3*01, TRAV8N-2*01, TRAV16N*01, TRAV13N-4*01, TRAV14N-3*01, TRAV15N-3*01, TRAV7-2*02, TRAV6-3*02, TRAV7-3*04, TRAV6-4*03, TRAV7-4*02, TRAV8-1*03, TRAV9-1*02, TRAV6-5*04, TRAV16D/DV11*02, TRAV15D-1/DV6D-1*02.
22 July 2010 - 17 August 2010
- Addition of:
  - 73 Bos taurus TRDV genes and alleles.
  - 5 Bos taurus TRDD genes and alleles.
  - 3 Bos taurus TRDJ genes and alleles.
  - 1 Bos taurus TRDC genes and alleles.
  - 52 Bos taurus TRAJ genes and alleles.
  - 1 Bos taurus TRAC genes and alleles.
9 June 2010
- Update of the human and mouse TRAV numbering in accordance with IMGT/3Dstructure-DB.
28 May 2010
- Addition of the orphon on chromosome 21 Homo sapiens IGHV1/OR21-1 gene and allele (1 ORF).
5 May 2010
- Addition of Homo sapiens IGLC2A, IGLC2B, IGLC2C, IGLC2D, IGLJ2A, IGLJ2B, IGLJ2C and IGLJ2D genes and alleles.
March 2010
- Addition of constant Danio rerio IGHM, IGHD, IGHZ genes and alleles (1 functional, 2 ORF).
- Addition of 41 Danio rerio IGHV genes and alleles (35 functional, 5 ORF and 1 pseudogene), 7 Oncorhynchus mykiss IGHJ genes and alleles (7 functional) and 7 Oncorhynchus mykiss IGHD genes and alleles (7 functional).
- Addition of 11 Oryctolagus cuniculus IGHC genes and 27 alleles (27 functional).
February 2010
- Addition of 41 Danio rerio IGHV genes and alleles (35 functional, 5 ORF and 1 pseudogene), 7 Danio rerio IGHJ genes and alleles (7 functional) and 7 Danio rerio IGHD genes and alleles (7 functional).
- Addition of the orphon on chromosome Y Homo sapiens IGKV1/ORY-1 gene and allele (1 pseudogene).
January 2010
- Addition of 55 Oncorhynchus mykiss IGHV genes and 57 alleles (56 functional and 1 pseudogene).
- Addition of constant Oncorhynchus mykiss IGHM, IGHD, IGHT genes and alleles (3 functional).
- Addition of 66 Oryctolagus cuniculus IGHV genes and alleles (38 functional, 28 ORF), 6 Oryctolagus cuniculus IGHJ genes and 11 alleles (11 functional) and 11 Oryctolagus cuniculus IGHD genes and alleles (10 functional, 1 ORF).
- Addition of 68 Oryctolagus cuniculus IGKV genes and 70 alleles (66 functional, 1 ORF, 3 pseudogenes).
18 December 2009
- Addition of 7 Oncorhynchus mykiss IGHJ genes and alleles (7 functional), 9 Oncorhynchus mykiss IGHD genes and alleles (9 functional).
11 December 2009
- Homo sapiens IGHV1-45*02: the reference sequence is AB019438 (Z12306 becomes sequence from the literature).
- Homo sapiens IGHV1-67*01: the reference sequence is AB019437 (X92212 becomes sequence from the literature).
- Homo sapiens IGHV3-25*02: the reference sequence is AB019439 (Z12355 becomes sequence from the literature).
- Homo sapiens IGHV3-48*03: the reference sequence is U03893 (Z12358 becomes sequence from the literature).
- Homo sapiens IGHV3-73*01: the reference sequence is X70197 (Z27508 becomes sequence from the literature).
- Homo sapiens IGHV3-75*01: the reference sequence is AB019437 (Z27510 becomes sequence from the literature).
- Homo sapiens IGHV3-76*01: the reference sequence is AB019437 (Z12341 becomes sequence from the literature).
- Homo sapiens IGHV4-34*01: the reference sequence is AB019439 (X92278 becomes sequence from the literature).
- Homo sapiens IGHV4-39*01: the reference sequence is AB019439 (L10094 becomes sequence from the literature).
- Homo sapiens IGHV4-59*01: the reference sequence is AB019438 (L10088 becomes sequence from the literature).
29 October 2009
- Addition of 45 Oncorhynchus mykiss TRBV genes and alleles (39 functional, 1 ORF and 5 pseudogenes).
23 October 2009
- Addition of 163 Rattus norvegicus IGKV genes and alleles (136 functional, 6 ORF and 21 pseudogenes).
20 October 2009
- Homo sapiens TRAV12-3*01: the reference sequence is AE000659 (X06193, is sequence from the literature).

LOCALIZATION IN GENOME ASSEMBLIES updates

01 December 2022
- The localizations of Gorilla gorilla gorilla (western lowland gorilla) TRG genes in the NCBI Susie3, chromosome 7, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
01 December 2022
- The localizations of Gorilla gorilla gorilla (western lowland gorilla) TRG genes in the NCBI Kamilah_GGO_v0, chromosome 7, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
01 December 2022
- The localizations of Gorilla gorilla gorilla (western lowland gorilla) IGK genes in the NCBI Susie3, chromosome 2A, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
01 December 2022
- The localizations of Gorilla gorilla gorilla (western lowland gorilla) IGK genes in the NCBI Kamilah_GGO_v0, chromosome 2A, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
08 April 2022
- The localizations of Gorilla gorilla gorilla (western lowland gorilla) IGH genes in the NCBI Susie3, chromosome 14, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
06 April 2022
- The localizations of Gorilla gorilla gorilla (western lowland gorilla) IGH genes in the NCBI Kamilah_GGO_v0, chromosome 14, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
29 March 2022
- The localizations of Macaca fascicularis (crab-eating macaque ) TRB genes in the NCBI Macaca_fascicularis_5.0, chromosome 3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
22 March 2022
- The localizations of Bos taurus (bovine) TRB genes in the NCBI ARS-UCD1.2, chromosome 4, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
16 March 2022
- The localizations of Mus musculus (mouse, C57BL/6J) IGH genes in the NCBI GRCm38.p6 assembly, chromosome 12, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
3 March 2022
- The localizations of Mus musculus (mouse, C57BL/6J) IGH genes in the NCBI GRCm39 assembly, chromosome 12, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
31 August 2021
- The localizations of Macaca mulatta (Rhesus monkey, AG07107) IGH genes in the NCBI Mmul_10 assembly, chromosome 7, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Macaca mulatta (Rhesus monkey, 17573) IGH genes in the NCBI Mmul_8.0.1 assembly, chromosome 7, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
27 April 2021
- The localizations of Macaca mulatta (Rhesus monkey, AG07107) IGK genes in the NCBI Mmul_10 assembly, chromosome 13, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Macaca mulatta (Rhesus monkey, AG07107) TRB genes in the NCBI Mmul_10 assembly, chromosome 3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Macaca mulatta (Rhesus monkey, 17573) TRB genes in the NCBI Mmul_8.0.1 assembly, chromosome 3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
25 August 2020
- The localizations of Canis lupus familiaris (dog, Boxer) IGK genes in the NCBI CanFam3.1 assembly, chromosome 17, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
06 August 2020
- The localizations of Canis lupus familiaris (dog, Basenji) IGK genes in the NCBI Basenji_breed-1.1 assembly, chromosome 17, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Bos taurus (bovine, Hereford) TRA genes in the NCBI ARS-UCD1.2 assembly, chromosome 10, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Bos taurus (bovine, Hereford) TRD genes in the NCBI ARS-UCD1.2 assembly, chromosome 10, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Ovis aries (sheep, Rambouillet) TRA genes in the NCBI Oar_rambouillet_v1.0 assembly, chromosome 7, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Ovis aries (sheep, Rambouillet) TRD genes in the NCBI Oar_rambouillet_v1.0 assembly, chromosome 7, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
06 July 2020
- The localizations of Ovis aries (sheep, Rambouillet) IGL genes in the NCBI Oar_rambouillet_v1.0 assembly, chromosome 17, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
19 June 2020
- The localizations of Camelus dromedarius (Arabian camel, African) IGK genes in the NCBI CamDro3 assembly, chromosome 28, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
07 April 2020
- Update of the version of Human GRCh38 assembly: gene localizations are provided for Genome Reference Consortium Human Build 38 patch release 13 (GRCh38.p13), GCF_000001405.39. No modification was noted, for Homo sapiens (human) locus between GRCh38.p13 and GRCh38.p12.
  (direct links: IGH, IGK, IGL, TRA, TRD, TRB TRG)
3 March 2020
- The localizations of Equus caballus (Horse, thoroughbred) IGK genes in the NCBI EquCab3.0 assembly, chromosome 15, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
18 February 2020
- Update of the version of Human GRCh38 assembly: gene localizations are provided for Genome Reference Consortium Human Build 38 patch release 12 (GRCh38.p12), GCF_000001405.38. No modification was noted, for Homo sapiens (human) loci between GRCh38.p12 and GRCh38.p7.
12 February 2020
- The localizations of Macaca mulatta (Rhesus monkey, AG07107) TRG genes in the NCBI Mmul_10 assembly, chromosome 3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
16 January 2020
- The localizations of Homo sapiens (human) TRAV46, TRAVA, TRAVB, TRAVC, TRAV11-1, TRAV14-1, TRAV8-6-1 genes in the NCBI GRCh38.7 assembly, chromosome 14, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Homo sapiens (human) TRAV1-2*03, TRAV6*07, TRAV8-2*03, TRAV9-2*02, TRAV10*02, TRAV20*02, TRAV23/DV6*05, TRAV26-1*02, TRAV27*03, TRAV28*02, TRAV29/DV5*04, TRAV30*05, TRAV31*02, TRAV32*01, TRAV35*03, TRAV36/DV7*05, TRAJ37*02, TRAJ32*02, TRAJ24*03, TRAJ16*02, TRAJ8*02 alleles in the NCBI GRCh38.7 assembly, chromosome 14, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
30 December 2019
- The localizations of Felis catus (cat, Abyssinian) TRB genes in the NCBI Felis_catus_9.0 assembly, chromosome A2, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Ovis aries (sheep, Texel) IGK genes in the NCBI Oar_v4.0 assembly, chromosome 3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Macaca mulatta (Rhesus monkey, 17573) TRA genes in the NCBI Mmul_8.0.1 assembly, chromosome 7, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Macaca mulatta (Rhesus monkey, 17573) TRD genes in the NCBI Mmul_8.0.1 assembly, chromosome 7, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
04 November 2019
- The localizations of Felis catus (cat, Abyssinian) TRA genes in the NCBI Felis_catus_9.0 assembly, chromosome B3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Felis catus (cat, Abyssinian) TRD genes in the NCBI Felis_catus_9.0 assembly, chromosome B3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
25 October 2019
- The localizations of Oncorhynchus mykiss (rainbow trout, Swanson) IGH genes in the NCBI Omyk_1.0 assembly, chromosome 13 (locus A), are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Oncorhynchus mykiss (rainbow trout, Swanson) IGH genes in the NCBI Omyk_1.0 assembly, chromosome 12 (locus B), are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
13 September 2019
- The localizations of Capra hircus (goat, San Clemente) IGL genes in the NCBI ARS1 assembly, chromosome 17, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
12 September 2019
- The localizations of Felis catus (cat, Abyssinian) IGK genes in the NCBI Felis_catus_9.0 assembly, chromosome A3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
30 July 2019
- The localizations of Capra hircus (goat, San Clemente) IGK genes in the NCBI ARS1 assembly, chromosome 11, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
22 July 2019
- The localizations of Bos taurus (bovine, Hereford) IGK genes in the NCBI ARS-UCD1.2 assembly, chromosome 11, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Bos taurus (bovine, Hereford) IGL genes in the NCBI ARS-UCD1.2 assembly, chromosome 17, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
16 May 2019
- The localizations of Ovis aries (sheep, Rambouillet) TRB genes in the NCBI Oar_rambouillet_v1.0 assembly, chromosome 4, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
7 May 2019
- The localizations of Felis catus (cat, Abyssinian) TRG genes in the NCBI Felis_catus_9.0 assembly, chromosome A2, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
1 April 2019
- The localizations of Felis catus (cat, Abyssinian) IGL genes in the NCBI Felis_catus_9.0 assembly, chromosome D3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Gallus gallus (chicken, Red Jungle fowl) IGL genes in the NCBI GRCg6a assembly, chromosome 15, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Gallus gallus (chicken, Red Jungle fowl) IGH genes in the NCBI GRCg6a assembly, chromosome 31, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Oryctlagus cuniculus (rabbit, Thorbecke inbred) TRA genes in the NCBI OryCun2.0 assembly, chromosome 17, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Oryctlagus cuniculus (rabbit, Thorbecke inbred) TRD genes in the NCBI OryCun2.0 assembly, chromosome 17, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
26 March 2019
- The localizations of Oryctlagus cuniculus (rabbit, Thorbecke inbred) TRG genes in the NCBI OryCun2.0 assembly, chromosome 10, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
19 March 2019
- The localizations of Sus scrofa (pig, Duroc) TRB genes in the NCBI Sscrofa11.1 assembly, chromosome 18, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
23 January 2019
- The localizations of Canis lupus familiaris (dog, boxer) IGL genes in the NCBI CanFam3.1 assembly, chromosome 26, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
26 July 2018
- The localizations of Canis lupus familiaris (dog, boxer) IGH genes in the NCBI CanFam3.1 assembly, chromosome 8, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
26 April 2018
- The localizations of Canis lupus familiaris (dog, boxer) TRG genes in the NCBI CanFam3.1 assembly, chromosome 18, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
24 November 2017
- The localizations of Danio rerio (zebrafish, Tuebingen) IGH genes in the NCBI GRCz11 assembly, chromosome 3, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
23 November 2017
- The localizations of Danio rerio (zebrafish, Tuebingen) TRA genes in the NCBI GRCz11 assembly, chromosome 2, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Danio rerio (zebrafish, Tuebingen) TRD genes in the NCBI GRCz11 assembly, chromosome 2, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
22 November 2017
- The localizations of Canis lupus familiaris (dog, boxer) TRB genes in the NCBI CanFam3.1 assembly, chromosome 16, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
21 November 2017
- The localizations of Canis lupus familiaris (dog, boxer) TRA genes in the NCBI CanFam3.1 assembly, chromosome 8, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
- The localizations of Canis lupus familiaris (dog, boxer) TRD genes in the NCBI CanFam3.1 assembly, chromosome 8, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
20 November 2017
- The localizations of Canis lupus familiaris (dog, boxer) IGK genes in the NCBI CanFam3.1 assembly, chromosome 17, are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
09 October 2017
- The localizations of Homo sapiens (human) IGL genes (22q11.2) in the NCBI GRCh38.7 assembly are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section of the IMGT/GENE-DB Query page.
  (direct link)
29 September 2017
- The localizations of Homo sapiens (human) IGK (2p11.2), TRA (14q11.2) and TRG (7p14) genes in the NCBI GRCh38.7 are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section.
  (direct links for IGK, TRA, TRG)
12 September 2017
- The localizations of Homo sapiens (human) TRD genes (14q11.2) in the NCBI GRCh38.7 assembly are integrated in the LOCALIZATION IN GENOME ASSEMBLIES section.
  (direct link)
1st July 2016
- Gene localizations are provided for Genome Reference Consortium Human Build 38 patch release 7, GRCh38.p7 (2016/03/21), Human genome Annotation Release 108, GCF_000001405.33. No modification was noted, for Homo sapiens (human) IGH (14q32) and TRB (7q34) between GRCh38.p7 and GRCh38.p2.
  (direct links for IGL, IGH, TRB)
9 June 2015
- Gene localizations are provided for Homo sapiens (human) IGH and TRB, assembly Genome Reference Consortium Human Build 38 patch release 2, GRCh38.p2 (2014/12/05), Human genome Annotation Release 107.

Created: 31/01/2003
Last updated: 22/08/2019

IMGT/GENE-DB data updates
IMGT®, the international ImMunoGeneTics information system®	http://www.imgt.org

IGKV gene old name	IGKV gene new name
IGKV(II)-6*01	IGKV(I)-6*01

TRDV gene old name	TRDV gene new name
TRDV2*01	TRDV5*01

TRAV gene old name	TRAV gene new name
TRAV43S2*01	TRAV13S2*01

IGLV gene old name	IGLV gene new name
IGLV1S6*01	IGLV1-15-1*01
IGLV1S9*01	IGLV1-21-1*01
IGLV1S10*01	IGLV1-21-2*02

TRDJ gene old name	TRDJ gene new name
TRDJ2*01	TRDJ4*01
TRDJ3*01	TRDJ2*01
TRDJ4*01	TRDJ3*01

TRG allele old name	TRG allele new name
TRGV2*01	TRGV2*02
TRGJ3*01	TRGJ3*02